基本介紹
研究領域,教育經歷,工作經歷,學術成就,出版教材,獲得獎勵,研究生培養,研發的新藥,發明專利,研究成就,學術論文代表作,社會職務,
研究領域
教育經歷
工作經歷
- 2012年2月至2014年12月,還擔任美國南佛羅里達大學(University of South Florida, USF)主管國際醫學發展項目的協理副校長(Associate Vice President)。
學術成就
出版教材
- SCI論文發表的知名雜誌包括ACS Nano、Adv Funct Mater、PNAS、Cancer Res、Chem Eng J、Clin Cancer Res、Small、BMC Med、Drug Discov Today、Drug Resist Update、Nanoscale、Clin Pharmacol Ther、 J Control Release、 J Am Soc Nephrol、Autophagy、 J Biol Chem、 Anal Chem、 J Pharmacol Exp Ther、 Biochem Pharmacol、 Drug Metab Dispos、Drug Metab Rev等。
- 主編或參編英文專著19本。
- 已發表學術會議摘要550篇以上。
- 已被全球180多家知名大學和附屬醫院邀請發表250次以上的專題學術演講。
獲得獎勵
- 在海內外多次獲得科研創新和教學優異獎。獲得南佛羅里達大學(University of South Florida, USF)2014年最佳研究和創新獎(全校該年僅4人獲得)。
研究生培養
研發的新藥
- 已經申報多項新藥、納米劑型設計、集成催化劑等方面的美國和中國專利。
發明專利
2. Zhou SF, Tan J, & Yin J. Self-assembled targeted inclusion complexes for drug delivery. 2016年2月4日申請,2018年1月25日批准,United States, 美國專利商標局(USPTO), 美國專利號:US20180021456A1。
3. Qin Y & Zhou SF. Targeted graphene quantum dot-based theranostics. 2019年12月3日批准,United States, 美國專利商標局(USPTO), 美國專利號:10493170.
研究成就
獲得的教學成果獎
獲評的擔任主講的福建省一流課程
- 2020年,《大學生健康教育與維護》,福建省線上一流課程;
- 2020年,《生物化學》(全英課),福建省線上線下混合式一流課程;
- 2020年,《蛋白質鑑定及生物藥合成路徑模擬虛擬仿真實驗》,福建省虛擬仿真實驗教學一流課程。
福建省本科高校教育教學改革研究項目
- 2017年,一般項目,福建省教育廳,基於工程教育認證標準的畢業要求評價體系的建立與驗證,主持,排名:1/6
獲評的擔任主講的華僑大學校級一流課程
- 華僑大學精品線上開放課程(2018年):《生物倫理學》、《人類的健康與疾病》
- 華僑大學2019年“課程思政”特色示範課堂:《生物倫理學》
- 華僑大學通識教育選修課程(2019年,第五批):《大學生健康教育與維護》、《生物倫理學》
- 華僑大學通識教育選修課程(2020年,第七批):《學術規範與論文寫作》
- 華僑大學通識教育選修課“金課”(第一批,2020年2月):《大學生健康教育與維護》、《生物倫理學》
華僑大學教師教學發展改革項目
- 2019年,華僑大學教師教學發展改革項目:本科專業基礎課程《生物化學》全英混合式教學的改革探索和效果評估,項目編號:19JF-JXGZ26,排名:1/4
學術論文代表作
- Fan L, Dai J, Huang Z, Xiao J, Li Q, Huang J*, Zhou SF*, & Zhan G*. Biomimetic Au/CeO2 catalysts decorated with hemin or ferrous phthalocyanine for improved CO oxidation via local synergistic effects. iScience 2020 Nov 23; 23(12): 101852. (影響因子:4.447)
- Fan L, Wang K, Xu K, Liang Z, Wang H, Zhou SF*, & Zhan G*. Structural isomerism of two Ce-BTC for fabricating Pt/CeO2 nanorods towards low-temperature CO oxidation. Small 2020 Oct; 16(40): e2003597. (影響因子:11.459)
- Hu P, Wu Z, Wang J, Huang Y, Liu Q, & Zhou SF*. Corrosion inhibiting performance and mechanism of protic ionic liquids as green brass inhibitors in nitric acid. Green Energy Environ 2020 Apr; 5(2): 214-222. (影響因子:6.350)
- Jiang W, Pei R, & Zhou SF*. 3D-printed xylanase within biocompatible polymers as excellent catalyst for lignocellulose degradation. Chem Eng J 2020 Jun 17; 400: 125920. (影響因子:10.650)
- Lai AN, Wang Z, Yin Q, Zhu RY, Hu PC, Zheng JW, & Zhou SF*. Comb-shaped fluorene-based poly (arylene ether sulfone nitrile) as anion exchange membrane. Int J Hydrogen Energy 2020 Apr 3; 45(19): 11148-11157. (影響因子:4.939)
- Liang S, Jiang W, Song Y, & Zhou SF*. Improvement and metabolomics-based analysis of D-lactic acid production from agro-industrial wastes by Lactobacillus delbrueckii submitted to adaptive laboratory evolution. J Agric Food Chem 2020 Jun 30; 68(28): 7660–7669. (影響因子:3.610)
- Liu D, Zhang Y, Zhu M, Yu Z, Ma X, Song Y, Zhou SF*, & Yang C*. A microfluidic-integrated multicolor immunosensor for visual detection of HIV-1 p24 antigen with the naked eyes. Anal Chem 2020 Jul 29; 92(17): 11826–11833. (影響因子:6.350)
- Pan ST, Zhou J, Yang F, Zhou SF*, & Ren T*. Proteomics reveals a therapeutic vulnerability via the combined blockade of APE1 and autophagy in lung cancer A549 cells. BMC Cancer 2020 Dec; 20(1): 1-11. (影響因子:3.150)
- Pei R, Fan LL, Zhao FG, Xiao JR, Yang Y, Lai AN, Zhou SF*, & Zhan GW*. 3D-Printed metal-organic frameworks within biocompatible polymers as excellent adsorbents for organic dyes removal. J Hazard Mater 2020 Feb 15; 384: 121418. (影響因子:8.000)
- Wu Z, Gao L, Wang J, Zhao F, Hua D*, Japip S, Xiao J, Zhang X, Zhou SF*, & Zhan G*. Preparation of glycine-mediated graphene oxide/g-C3N4 lamellar membranes for nanofiltration. J Membr Sci 2020 Mar 1; 601: 117948. (影響因子:7.210)
- Xiao J, Fan L, Zhao F, Huang Z, Zhou SF*, & Zhan GW*. Kinetic analysis of the synergistic effect of NaBH4 treatment and Co-Pi coating on Fe2O3 photoanodes for photo electrochemical water oxidation. J Catal 2020; 381: 139-149. (影響因子:7.888)
- Xiao J, Zhao F, Zhong J, Huang Z, L Fan, Peng L, Zhou SF*, & Zhan G*. Performance enhancement of hematite photoanode with oxygen defects for water splitting. Chem Eng J 2020 Dec 15; 402:126163. (影響因子:10.650)
- Zhao F, Zhan G*, & Zhou SF*. Intercalation of laminar Cu-Al LDH with molecular TCPP(M) (M=Zn, Co, Ni, Fe) towards high-performance CO2 hydrogenation catalysts. Nanoscale 2020 Jun 28; 12(24): 13145-13156. (影響因子:6.895)
- 陳志超,張紅,周樹鋒*,崔秀靈*. 過硫酸鉀促進2-炔芳基腈與亞磺酸鈉的自由基串聯環化:構築稠環環戊烯並[gh]菲啶(英文)有機化學 (Chin J Org Chem) 2020 Aug; 40: 1-9.
- Chen LC, Zhou SF, Su LC, & Song JB*. Gas-mediated cancer bioimaging and therapy. ACS Nano 2019 Oct 22; 13(10): 10887-10917. (影響因子:13.700)
- Fan LL, Zhao FG, Huang ZL, Chen B, Zhou SF*, & Zhan GW*. Partial deligandation of M/Ce-BTC nanorods (M = Au, Cu, au-cu) with “quasi-MOF” structures towards improving catalytic activity and stability. Appl Catal A-Gen 2019; 572: 34–43. (影響因子:5.006)
- Huang ZL, Fan LL, Zhao FG, Chen B, Xu KJ, Zhou SF, Zhang JL, Li QB, Hua D, & Zhan GW*. Rational engineering of multi-layered Co3O4/ZnO nanocatalysts through chemical transformations from Matryoshka-type ZIFs. Adv Funct Mater 2019 Oct 17; 29(42): 1903774. (影響因子:14.860)
- Lin XX, Su JL, Lin HG, Sun XY, Liu B, Kankala RK, & Zhou SF*. Luminescent carbon nanodots based aptasensors for rapid detection of kanamycin residue. Talanta 2019 Sep 1; 202: 452-459. (影響因子:4.930)
- Zhan GW*, Fan LL, Zhao FG, Huang ZL, Chen B, Yang X, & Zhou SF. Fabrication of ultrathin 2D Cu-BDC nanosheets and the derived integrated MOF nanocomposites. Adv Funct Mater 2019; 29(9): 1806720. (影響因子:14.860)
- Zhao FG, Fan LL, Xu KJ, Hua D*, Zhan GW*, & Zhou SF*. Hierarchical sheet-like Cu/Zn/Al nanocatalysts derived from LDH/MOF composites for CO2 hydrogenation to methanol. J CO2 Util 2019 Oct; 33: 222-232. (影響因子: 5.350)
- Zhan G, Fan L, Zhou SF, & Yang X. Fabrication of integrated Cu2O@HKUST-1@Au nanocatalysts via galvanic replacements towards alcohols oxidation application. ACS Appl Mater Inter 2018 Oct 17; 10(41): 35234-35243. (影響因子:8.330)
- Shang YY, Yao M, Zhou ZW, Jian-Cui, Li-Xia, Hu RY, Yu YY, Qiong-Gao, Biao-Yang, Liu YX, Dang J, Zhou SF*, & Nan-Yu*. Alisertib promotes apoptosis and autophagy in melanoma through p38 MAPK-mediated aurora a signaling. Oncotarget 2017 Nov 6; 8(63): 107076-107088. (影響因子:6.359)
- Yao M, Shang YY, Zhou ZW, Yang YX, Wu YS, Guan LF, Wang XY, Zhou SF*, & Wei X*. The research on lapatinib in autophagy, cell cycle arrest and epithelial to mesenchymal transition via Wnt/ErK/PI3K-AKT signaling pathway in human cutaneous squamous cell carcinoma. J Cancer 2017 Jan 15; 8(2): 220-226. (影響因子:3.565)
- He SJ, Shu LP, Zhou ZW, Yang T, Duan W, Zhang X, He ZX*, & Zhou SF*. Inhibition of Aurora kinases induces apoptosis and autophagy via AURKB/p70S6K/RPL15 axis in human leukemia cells. Cancer Lett 2016 Nov 28; 382(2): 215-230. (影響因子:5.992)
- Lu X, Wang F, Xu C, Soodvilai S, Peng K, Su J, Zhao L, Yang KT, Feng Y, Zhou SF, Gustafsson JÅ, & Yang T*. Soluble (pro)renin receptor via β-catenin enhances urineconcentration capability as a target of liver X receptor. Proc Natl Acad Sci U S A 2016 Mar 29;113(13):E1898-1906. (影響因子:9.674)
- Wang F, Lu X, Peng K, Fang H, Zhou L, Su J, Nau A, Yang KT, Ichihara A, Lu A, Zhou SF, & Yang T*. Antidiuretic action of collecting duct (pro)renin receptor downstream of vasopressin and PGE2 receptor EP4. J Am Soc Nephrol 2016 Oct; 27(10): 3022-3034. (影響因子:9.343)
- Cheng J, Li X, Morgan D, Gordon M, Chen X, Wang ZH, Li HN, He LJ, Zhou SF*, & Cao CH*. Dendritic and Langerhans cells respond to Aβ peptides differently: implication for AD immunotherapy. Oncotarget 2015 Nov 3; 6(34): 35443-35457. (影響因子:6.359)
- He ZX, Chen XW, Zhou ZW, & Zhou SF*. Impact of physiological, pathological and environmental factors on the expression and activity of human cytochrome P450 2D6 and implications in precision medicine. Drug Metab Rev 2015 Nov 16; 47(4): 470-519. (影響因子:5.356)
- Wang F, Lu X, Liu M, Feng Y, Zhou SF, & Yang T*. Renal medullary (pro)renin receptor contributes to angiotensin II-induced hypertension in rats via activation of the local renin–angiotensin system. BMC Med 2015 Nov 10; 13: 278. (影響因子:7.249)
- Yin JJ, Shumyak SP, Burgess C, Zhou ZW, He ZX, Zhang XJ, Pan ST, Yang TX, Duan W, Qiu JX, & Zhou SF*. Controllable drug uptake and nongenomic response through estrogen-anchored chclodextrin drug complex. Int J Nanomed 2015 Jul 27; 10: 4717-4730. (影響因子:4.383)
- Zhou ZW, Chen XW, Sneed KB, Yang YX, Zhang X, He ZX, Chow K, Yang T, Duan W, & Zhou SF*. Clinical association between pharmacogenomics and adverse drug reactions. Drugs 2015 Apr 21; 75(6): 589-631. (影響因子:6.189)
- Li M, Yang Y, He ZX, Zhou ZW, Yang T, Guo P, Zhang X, & Zhou SF*. MicroRNA-561 promotes acetaminophen-induced hepatotoxicityin HepG2 cells and primary human hepatocytes through down-regulation of the nuclear receptor co-repressor dosage-sensitive sex reversal adrenal hypoplasia congenital critical region on X chromosome, gene 1 (DAX-1). Drug Metab Dispos 2014 Jan; 42(1): 44-61. (影響因子:3.252)
- Li YC, He SM, He ZX, Li M, Yang Y, Tang JX, Zhang X, Chow K, Zhou Q, Duan W, Zhou ZW, Yang T, Huang GH, Liu A, Qiu JX, Liu JP, & Zhou SF*. Plumbagin induces apoptotic and autophagic cell death through inhibition of the PI3K/Akt/mTOR pathway in human non-small cell lung cancer cells. Cancer Lett 2014 Mar 28; 344(2): 239-259. (影響因子:5.992)
- Wang LL, Li Y, & Zhou SF*. A bioinformatics approach for the phenotype prediction of non-synonymous single nucleotide polymorphisms in human cytochrome P450s. Drug Metab Dispos 2009 May; 37(5): 977-991. (影響因子:3.252)
- Wang LL, Zhang Z, Li Q, Yang R, Pei X, Xu Y, Wang J, Li Y*, & Zhou SF*. Ethanol exposure induces differential microRNA and target gene expression and teratogenic effects which can be suppressed by folic acid supplementation. Human Reproduction 2009 Mar; 24(3): 562-579. (影響因子:4.569)
- Wang XD, Li JL, Su QB, Guan S, Chen J, Du J, He YW, Zeng J, Zhang JX, Chen X, Liu YH, Huang M*, & Zhou SF*. Impact of the haplotypes of the human pregnane X receptor gene on the basal and St John’s wort-induced activity of cytochrome P450 3A4 enzyme.Br J Clin Pharmacol 2009 Feb; 67(2): 255-261. (影響因子:3.878)
- Zhou SF. Polymorphism of human cytochrome P450 2D6 and its clinical significance. Part I. Clin Pharmacokinet 2009 Nov; 48(11): 689-723. (影響因子:5.053)
- Zhou SF. Polymorphism of human cytochrome P450 2D6 and its clinical significance. Part II. Clin Pharmacokinet 2009 Dec; 48(12): 761-804. (影響因子:5.053)
- Cheng MB, Wang JC*, Li YH, Liu XY, Zhang X, Chen DW, Zhou SF, & Zhang Q*. Characterization of water-in-oil microemulsion for oral delivery of earthworm fibrinolytic enzyme. J Control Release 2008 Jul 2; 129(1): 41-48. (影響因子:7.705)
- Cao J, Chen X, Liang J, Yu XQ, Xu AL, Chan E, Wei D, Huang M, Wen JY, Yu XY, Li XT, Sheu FS, & Zhou SF*. Role of P-glycoprotein in the intestinal absorption of glabridin, an active flavonoid extracted from the root of Glycyrrhiza glabra (licorice). Drug Metab Dispos 2007 Apr; 35(4): 539-553. (影響因子:3.252)
- Yu XY, Lin SG, Wang XM, Liu Y, Zhang B, Lin QX, Yang M, & Zhou SF*. Evidence for coexistence of three β-adrenoceptor subtypes in human peripheral lymphocytes. Clin Pharmacol Ther 2007 May; 81(5): 654-658. 17361123. (影響因子:7.903)
- Zhou SF*, Zhou ZW, Chen X,Yu X, Li CG, Xue CC, & Herington A. Identification of drugs that interact with herbal medicines. Drug Discov Today 2007 Aug; 12(15-16): 664-673. (影響因子:7.321)
- Chen J, Yang XX, Huang M, Hu ZP, He M, Duan W, Chan E, Sheu FS, Chen X, & Zhou SF*. Small interfering RNA-mediated silencing of cytochrome P450 3A4 gene. Drug Metab Dispos 2006 Sep; 34(9): 1650-1657.(影響因子:3.252)
- Hu ZP, Yang XX, Chan SY, Xu AL, Duan W, Zhu YZ, Sheu FS, Boelsterli UA, Chan E, Zhang Q, Wang JC, Ee PL, Koh HL, Huang M, & Zhou SF*. St. John’s wort attenuates irinotecan-induced diarrhea via down-regulation of intestinal pro-inflammatory cytokines and inhibition of intestinal epithelial apoptosis. Toxicol Appl Pharmacol 2006 Oct 15; 216(2): 225-237. (影響因子:3.705)
- Yang XX, Hu ZP, Xu AL, Duan W, Zhu YZ, Huang M, Sheu FS, Zhang Q, Bian JS, Chan E, Li X, Wang JC, & Zhou SF*. A mechanistic study on reduced toxicity of irinotecan by coadministered thalidomide, a tumor necrosisfactor-α inhibitor. J Pharmacol Exp Ther 2006 Oct; 319(1): 82-104. (影響因子:3.972)
- Yeong SS, Zhu Y, Smith D, Verma C, Lim WG, Tan BJ, Li QT, Cheung NS, Cai M, Zhu YZ, Zhou SF, Tan SL, & Duan W*. The last 10 amino acid residues beyond the hydrophobic motif are critical for the catalytic competence and function of protein kinase Cα. J Biol Chem 2006 Oct 13; 281(41): 30768-30781. (影響因子:4.573)
- Zhang J, Huang M, Guan S, Bi HC, Pan Y, Duan W, Chan SY, Chen X, Hong YH, Bian JS, Yang HY, & Zhou SF*. A mechanistic study of the intestinal absorption of cryptotanshinone, the major active constituent of Salvia miltiorrhiza. J Pharmacol Exp Ther 2006 Oct; 317(3): 1285-1294. (影響因子:3.972)
- Hu Z, Yang X, Ho PC, Chan SY, Heng PW, Chan E, Duan W, Koh HL, & Zhou SF*. Herb-drug interactions: a literature review. Drugs 2005 Jun; 65(9): 1-44. (影響因子:6.189)
- Zhang J, Tian Q, Chan SY, Duan W, & Zhou SF*. Insights into the resistance to oxazaphosphorines and potential approaches to its circumvention. Drug Resist Updat 2005 Oct; 8(5): 271-297. (影響因子:9.121)
- Zhou SF*,Chan SY, Goh BC, Chan E, Duan W, Huang M, & McLeod HL. Mechanism-based inhibition of CYP3A4 by therapeutic drugs. Clin Pharmacokinet 2005 Mar;44(3): 279-304. (影響因子:5.053)
- Zhu Y, Dong Q, Tan BJ, Lim WG, Zhou SF, & Duan W. The PKCα-D294G mutant found in pituitary and thyroid tumors fails to transduce extracellular signals. Cancer Res 2005 Jun 1; 65(11): 4520-4524. (影響因子:9.329)
- Zhou SF*, Kestell P, Baguley BC, & Paxton JW. Preclinical factors influencing the relative contributions of Phase I and II enzymes to the metabolism of the experimental anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid. Biochem Pharmacol 2003 Jan 1; 65(1): 109-120. (影響因子:5.009)
- Zhou SF*, Kestell P, Baguley BC, & Paxton JW. Preclinical factors affecting the interindividual variability in the clearance of the experimental anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid. Biochem Pharmacol 2003 Jun 1; 65(11): 1853-1865. (影響因子:5.009)
- Zhou SF, Paxton JW, Tingle MD, & Kestell P. Identification of the cytochrome P450 isoenzyme for the 6-methylhydroxylation of the novel antitumour agent 5,6-dimethylxanthenone-4-acetic acid.Drug Metab Dispos 2000 Dec 1; 28(12): 1449-1456. (影響因子:3.252)