preclinical,英語單詞,主要用作形容詞,作形容詞時譯為“臨床前的;現出症狀之前的潛伏期的”。
基本介紹
- 外文名:preclinical
- 詞性:形容詞
- 英式發音:[priː'klɪnɪk(ə)l]
- 釋義:臨床前的;現出症狀之前的潛伏期的
preclinical,英語單詞,主要用作形容詞,作形容詞時譯為“臨床前的;現出症狀之前的潛伏期的”。
臨床前 臨床前(preclinical)是2014年公布的藥學名詞。定義 為擬開發的新藥用於臨床試驗而開展的一系列實驗室研究工作的總稱。包括合成工藝、提取方法、理化性質及純度、處方篩選、製備工藝、檢驗方法、質量指標、穩定性、藥理毒理、動物藥動學等。出處 《藥學名詞》第二版。
④前期症狀者(presym- ptomatic),或前臨床病人(preclinical);⑤臨床病人。如得不到控制,可發展到下一個譜階;⑥死亡。基本概念 各譜階間界線互相交錯,並非截然分開。疾病一般由前階向後階發展,譜階演替過程的速度與病種、環境等多種因素有關,特別在前期階段,如採取某種防治措施或去除環境危險因素後則可...
美國國家醫學圖書館分類法是專門針對健康科學而設的分類法。NLM分類法與LC分類法很有關係,NLM分類法是利用LC分類法中的空號QS-QZ,用來表示醫預科學(preclinical science)和R(medicine),因為這些主題與NLM分類法重複。另外,美國國家醫學圖書館也極少使用LC分類表中的K(Law),而將有關醫學的法律作品依相關主題各入...
Preclinical candidate compounds ,臨床前候選化合物 物質簡介 有生物活性的物質很多,但是能夠成為藥物的卻很少,當一個化合物被合成出來,通過了諸如細胞活性,選擇性篩選,並進一步完成藥代動力學和各種毒性測試,安全性測試後,便基本上達到了臨床前候選化合物的標準。PCC不是最終的藥物,一個化合物符合PCC標準後,...
human diseases andmedical conditions. These products are part of our Infoknowmics™ Knowledgebasebecause they disclosed development activity in the past 9 years. The indexincludes all types of drugs across all clinical indications. It includes drugsthat are currently in the discovery, preclinical or...
臨床與衛生 (Clinical, Preclinical and Health) - 101-125 自然科學 (Physical Sciences) - 126-150 經濟學與商業 (Business and Economics) - 151-175 工程與技術 (Engineering and Technology) - 176-200 U.S.News 世界大學排名——2019 [29] 農業科學 (Agricultural Science) - 14 奧胡斯大學環境與生態學...
Reading Materials (Ⅱ) Preclinical Safety and Toxicology Testing of DNA Vaccine Additional Information Exercises Lesson 14 Text A Bioconversion of Cellulose and Hemicellulose to Ethanol Text B Algae-Based Fuels Set to Bloom Reading Materials (Ⅰ) Biodiversity Reading Materials (Ⅱ) Hydrogen Production by...
新藥臨床前藥效學(new drug preclinical pharmacodynamics)研究包括主要藥效學研究和一般毒理學研究。評價一個新藥一般主要是從它的主要藥效學作用入手,即從它預期用於臨床預防、診斷和治療的目的的藥理作用開始,通過對主要藥效學的評價,可進一步弄清新藥作用的強度和特點,如果可能還應闡明主要藥理的作用部位和作用機理。
甘肅省新藥臨床前研究重點實驗室(Key Lab of Preclinical Study for New Drugs of Gansu Province)(蘭州大學)是在甘肅省科技廳領導下、依託蘭州大學,聯合多學科、多專業組建的甘肅省首批省級重點實驗室之一。1999年5月籌建,2002年10月通過甘肅省科技廳組織的專家驗收,並正式對外開放,最初的名稱為甘肅省中藥...
[63] Zhai QQ, Gong GQ, Liu Z, Luo Y, Xia M, Xing GW, You XF, Wang YF*. Preclinical pharmacokinetic analysis of SNX-2112, a novel Hsp90 inhibitor, in rats. Biomed Pharmacother. 2011, 65(2):132-136.[64] Sun F, Liu JY, He F, Liu Z, Wang R, Wang DM, Wang YF*, Y...
Memory 114 Pharmacokinetics and Metabolism of Clausenamide Enantiomers 119 Metabolic Transformation of Clausenamide 142 Preclinical Safety Evaluation and General Pharmacology of (-)Clausenamide 148 Optical Separation and Quality Research of Clausenamide Enantiomers 157 Abstracts in English and Chinese 173 ...
新藥臨床毒理學new drug preclinical toxic}}.tior)新藥臨床毒理學是研究新藥的安全性。任何一種新藥被推薦卜臨床 之前,首要的是保證安全與有效,而保證安全是毒理學應回答 的問題,新藥臨床毒理學的任務在於回答藥物的安全劑量范 圍,即劑量和不良反應之間的關係。選擇性即藥物毒性作用 部位。毒性性質即藥物的毒性...
《Molecular cancer therapeutics》是2001年創辦的期刊。期刊適用範圍 Molecular Cancer Therapeutics strives to be the top choice for publishing the best science in the discovery and preclinical development of novel therapeutic agents for oncology, preclinical studies of approved therapeutics, mechanisms of drug...
13. Li, MY; Li, HQ; Cheng, XL; Wang, XP; Li, L;Zhou, TY*, and Lu, W*. Preclinical Pharmacokinetic/Pharmacodynamic Models to Predict Schedule-Dependent Interaction between Erlotinib and Gemcitabine. Pharm Res. 2013, 30, 1400-1408.14.Zhou, TY; Huang, CQ; Chen, Y; Xu, JJ; Shanbhag...
Development and preclinical characterization of a humanized antibody targeting CXCL12. Clin Cancer Res. 2013 Aug 15; 19(16):4433-45. Zhong C, Wang J, Li B, Xiang H, Ultsch M, Coons M, Wong T, Chiang NY, Clark S, Clark R, Quintana L, Gribling P, Suto E, Barck K, Corpuz R, ...
(2023) Chinese Preclinical Alzheimer’s Disease Study (C-PAS): Design and Challenge from PET Acceptance. The Journal of Prevention of Alzheimer’s Disease, https://doi.org/10.14283/jpad.2023.49 (IF(2021)= 5.020, 26.65%ile, Q2, 57/212, Clinical Neurology, SCIE) Han, Y.M.Y., Chan, M...
9PRECLINICAL TESTINGAND VALIDATION OF NOVELANTICANCER AGENTS I0SURROGATE END POINTS ANDBIOMARKERS FOR EARLY TRIALSOF NOVEL ANTICANCER AGENTS 11REGULATORY CONSIDERATIONSIN CLINICAL TRIALS OF NOVELANTICANCER DRUGS 12IMPROVING THE EFFICACYAND SAFETY OF ANTICANCERAGENTS—THE ROLEOF PHARMACOGENETICS 13 Imaging of ...
8.XuYouzhi,LuWenjie,YangPeng,PengWen,WangChunting,LiManli,LiYan,LiGuobo,MengNana,LinHongjun,KanLixin,WangSiying,YangShengyong,YuLuoting,ZhaoYingLan.AsmallmolecularagentYL529inhibitsVEGF-D-inducedlymphangiogenesisandmetastasisinpreclinicaltumormodelsinadditiontoitsknownantitumoractivities. BMCCancer. 2015Jul 18...
魚鱗病綜合徵是一組皮膚症狀表現為魚鱗病樣損害的遺傳性疾病。Preclinical progress has been achieved in the treatment of wounds, epidermolysis bullosa and ichthyosis.前期的臨床實驗在治療創傷,大皰性表皮鬆解症和魚鱗病上已經取得了進展。Ichthyosis's morbidity factor is various.魚鱗病的發病因素是多方面的。
the second is to develop anti-cancer chemical agents that target drug resistant cancers or molecular probes to understand biological processes. The drug development is a very long process. Our focus is to discover and optimize lead compounds, study the mechanism of action, and complete preclinical ...
Project Title: The preclinical research of monoclonal antibody drug treatment for diabetic foot targeting the blood vessels.Grant Duration: One year with non-cost extension of an additional year allowable.Grant Amount: Total amount: $60,000; $50,000 to Zhongshan School of Medicine, Sun ...