簡介,分類,病毒載體,非病毒載體,
簡介
gene delivery即基因載體，又稱為gene vector。可以將目的基因導入靶細胞內，然後釋放目的基因，使得目的基因進行表達，從而達到治療特定疾病的目的。
分類
病毒載體
即以滅活的病毒作為載體將目的基因導入靶細胞。
非病毒載體
即以非病毒載體如脂質體、陽離子聚合物等為載體將目的基因導入靶細胞。
簡介gene delivery即基因載體,又稱為gene vector。可以將目的基因導入靶細胞內,然後釋放目的基因,使得目的基因進行表達,從而達到治療特定疾病的目的。分類病毒載體即以...
他們開發了一種光誘導的基因傳遞系統(gene delivery system):將DNA分子和光敏感化合物組裝進一個簡單的結構中,進而使實驗操作對細胞的毒害降低到最小。...
基因治療載體材料(gene delivery material),或稱基因載體(gene vector)是為治療目的,將基因導入細胞的材料。基因載體可以把目的基因送入靶細胞內,然後將目的基因釋放...
3. Pack, D.W., Hoffman, A.S., Pun, S., Stayton, P.S.Design and development of polymers for gene delivery:Nature Reviews Drug Discovery ,2005:...
Zhuo,X.-L. Jiang*, Reduction Biodegradable Brushed PDMAEMA Derivatives Synthesized by ATRP and Click Chemistry for Gene Delivery, Acta Biomater, 2013, 9,...
“Cyclen-based cationic lipids for highly efficient gene delivery towards tumor cells” PLoS One 2011, 6(8), e23134.16. Huang, Q.-D.; Ou, W.-J...
Zhong*, Advanced Drug and Gene Delivery Systems Based on Functional Biodegradable Polycarbonates and Copolymers, J. Control. Release 2014, http://dx.doi....
Shuai*,“Polyethylenimine-grafted Copolymer of Poly(L-lysine) and Poly(ethylene glycol) for Gene Delivery”,Biomaterials,Doi:10.1016/j.biomaterials.2010.10...
4. Wang CQ, Wu JL, Zhuo RX, Cheng SX*, Protamine sulfate/calcium carbonate/plasmid DNA ternary nanoparticles for efficient gene delivery, Mol BioSyst ...
崔建民Ultrasound mediated drug/gene delivery 6. Zhou Y., Yang K., Cui J., Ye J.Y., Deng C.X. (2012) Controlled permeation of cell membrane by ...