程巳雪，博士，教授，武漢大學化學學院生物醫用高分子材料教育部重點實驗室（教授）
基本介紹
- 中文名：程巳雪
- 國籍：中國
- 出生日期：1971年4月
- 職業：教授
- 畢業院校：新加坡國立大學
- 職稱：教授（博導）
- 學歷學位：新加坡國立大學博士
- 研究方向：生物醫用高分子
人物經歷,主講課程,研究方向,主要貢獻,
人物經歷
1992年學士華南理工大學。
1995年碩士中國科學技術大學。
2000年博士新加坡國立大學。
2000年1月-2001年1月新加坡材料研究與工程研究所（研究助理）。
2001年1月-2003年11月武漢大學化學學院生物醫用高分子材料教育部重點實驗室（副教授）。
2003年11月武漢大學化學學院生物醫用高分子材料教育部重點實驗室（教授）。
主講課程
《化學套用英語》、《專業英語》。
研究方向
主要貢獻
科研課題
國家自然科學基金委面上項目《生物醫用液晶高分子複合材料的研究》、《可生物降解高分子仿生材料及其在藥物控制釋放和組織工程中的套用》。
代表論著
1. Chen B, Wu C, Zhuo RX, Cheng SX*, A self-assembled albumin based multiple drug delivery nanosystem to overcome multidrug resistance, RSC Adv 2015, 5, 6807-6814.
2. Liang P, Wang CQ, Chen H, Zhuo RX*, Si-Xue Cheng*, Multi-functional heparin–biotin/heparin/calcium carbonate/calcium phosphate nanoparticles for targeted co-delivery of gene and drug, Polym Inter DOI 10.1002/pi.4824.
3. Wu JL, Wang CQ, Zhuo RX, Cheng SX*, Multi-drug delivery system based on alginate/calcium carbonatehybrid nanoparticles for combination chemotherapy, Colloids Surf B: Biointerf 2014, 123, 498-505.
4. Wang CQ, Wu JL, Zhuo RX, Cheng SX*, Protamine sulfate/calcium carbonate/plasmid DNA ternary nanoparticles for efficient gene delivery, Mol BioSyst 2014, 10, 672-678.
5. Wang CQ, Gong MQ, Wu JL, Zhuo RX, Cheng SX*, Dual-functionalized calcium carbonate based gene delivery system for efficient gene delivery, RSC Adv 2014, 4, 38623–38629.
6. Zhao D, Wang CQ, Zhuo RX, Cheng SX*, Modification of nanostructured calcium carbonate for efficient gene delivery, Colloids Surf B: Biointerf 2014, 118, 111-116.
7. Liang P, Liu CJ, Zhuo RX, Cheng SX *, Self-assembled inorganic/organic hybrid nanoparticles with multi-functionalized surfaces for active targeting drug delivery, J Mater Chem B 2013, 1, 4243-4250.
8. Liang P, Zhao D, Wang CQ, Zong JY, Zhuo RX, Cheng SX*, Facile preparation of heparin/CaCO3/CaP hybrid nano-carriers with controllable size for anticancer drug delivery, Colloids Surf B: Biointerf 2013, 102, 783-788.
9. Wang J, Chen B, Zhao D, Peng Y, Zhuo RX, Cheng SX*, Peptide decorated calcium phosphate/carboxymethyl chitosan hybrid nanoparticles with improved drug delivery efficiency, Inter J Pharm 2013, 446, 205-210.
10. Chen S, Zhao D, Li F, Zhuo RX, Cheng SX*, Co-delivery of gene and drug with nanostructured calcium carbonate for cancer therapy, RSC Adv 2012, 2, 1820-1826.
11. Zhao D, Zhuo RX, Cheng SX*, Alginate modified nanostructured calcium carbonate with enhanced delivery efficiency for gene and drug delivery, Mol BioSyst 2012, 8, 753-759.
12. Zhao D, Liu CJ, Zhuo RX, Cheng SX*, Alginate/CaCO3 hybrid nanoparticles for efficient co-delivery of anti-tumor gene and drug. Mol Pharm 2012, 9, 2887-2893.
13. Zhao D, Zhuo RX, Cheng SX*, Modification of calcium carbonate based gene and drug delivery systems by a cell-penetrating peptide, Mol BioSyst 2012, 8, 3288–3294.
14. Zhang Q, Li F, Zhuo RX, Zhang XZ, Cheng SX*, Self-assembled complexes with dual-targeting property for gene delivery, J Mater Chem 2011, 21, 4636-4643.
15. Chen S, Cheng SX*, Zhuo RX, Self-assembly strategy for preparation of polymer-based nanoparticles for drug and gene delivery, Macromol Biosci 2011, 11, 576-589. (Invited feature article).
16. Wang J, Zong JY, Zhao D, Zhuo RX, Cheng SX*, In situ formation of chitosan-cyclodextrin nanospheres for drug delivery, Colloids Surf B: Biointerf 2011, 87, 198-202.
17. Chen S, Li F, Zhuo RX, Cheng SX*, Efficient non-viral gene delivery mediated by nanostructured calcium carbonate in solution-based transfection and solid-phase transfection, Mol BioSyst 2011, 7, 2841-2847.
18. Wang J, Chen JS, Zong JY, Zhao D, Li F, Zhuo RX, Cheng SX*, Calcium carbonate/carboxymethyl chitosan hybrid microspheres and nanospheres for drug delivery, J Phys Chem C 2010, 114, 18940-18945.
19. Zhang Q, Chen S, Zhuo RX, Zhang XZ, Cheng SX*, Self-assembled terplexes for targeted gene delivery with improved transfection, Bioconjugate Chem 2010, 21, 2086-2092.
20. Chen S, Zhuo RX, Cheng SX*, Enhanced gene transfection with addition of a cell-penetrating peptide in substrate-mediated gene delivery, J Gene Med 2010, 12, 705-713.
21. Zhang L, Hu CH, Cheng SX*, Zhuo RX*, Hyperbranched amphiphilic polymer with folate mediated targeting property, Colloids Surf B: Biointerf 2010, 79, 427-433.
22. Zhang L, Hu CH, Cheng SX*, Zhuo RX*, PEI grafted hyperbranched polymers with polyglycerol as a core for gene delivery, Colloids Surf B: Biointerf 2010, 76, 427-433.
23. Fu HL, Li YQ, Shao L, Cheng SX*, Zhang XZ, Zhuo RX, Gene expression mediated by dendrimer/DNA complexes encapsulated in biodegradable polymer microspheres, J Microencapsul 2010, 27, 345-354.
24. Yu CY, Jia LH, Cheng SX*, Zhang XZ, Zhuo RX, Fabrication of microparticle protein delivery systems based on calcium alginate, J Microencapsul 2010, 27, 171-177.
25. 付慧莉、程巳雪*、卓仁禧，用於基因傳遞系統控制釋放的可生物降解高分子材料, 高分子學報 2009, 2, 97-103.（邀請論文）.
26. Yu CY, Wei H, Zhang Q, Zhang XZ, Cheng SX*, Zhuo RX, Effect of ions on aggregation behavior of natural polymer alginate, J Phys Chem B 2009, 113, 14839–14843.
27. Zhang Q, Cheng SX*, Zhang XZ, Zhuo RX, Water soluble polymer protected Lipofectamine 2000/DNA complexes for solid-phase transfection, Macromol Biosci 2009, 9, 1262–1271.
28. Yu CY, Cao H, Zhang XC, Zhou FZ, Cheng SX*, Zhang XZ, Zhuo RX, Hybrid nanospheres and vesicles based on pectin as drug carriers, Langmuir 2009, 25, 11720-11726.
29. Li YQ, Li F, Zhang XZ, Cheng SX*, Zhuo RX, Three dimensional fast degrading polymer films for delivery of calcium phosphate/DNA co-precipitates in solid-phase transfection, J Mater Chem 2009, 19, 6733-6739.
30. Zhang Q, Zhao D, Zhang XZ, Cheng SX*, Zhuo RX*, Calcium phosphate/DNA co-precipitates encapsulated fast degrading polymer films for substrate-mediated gene delivery, J Biomed Mater Res B Appl Biomater 2009, 91B, 172-180.
31. Yu CY, Yin BC, Zhang W, Cheng SX*, Zhang XZ, Zhuo RX, Composite microparticle drug delivery systems based on chitosan, alginate and pectin with improved pH-sensitive drug release property, Colloids Surf B: Biointerf 2009, 68, 245-249.
32. 張橋、汪軍、趙東、程巳雪*，負載肝素及生物素化肝素修飾的納米粒子的基質介導基因傳遞系統，高分子學報 2011, 8, 824-831.（邀請論文）.
33. Yu CY, Jia LH, Yin BC, Zhang XZ, Cheng SX*, Zhuo RX, Fabrication of nanospheres and vesicles as drug carriers by self-assembly of alginate, J Phys Chem C 2008, 112, 16774–16778.
34. Fu HL, Cheng SX*, Zhang XZ, Zhuo RX, Dendrimer/DNA complexes encapsulated functional biodegradable polymer for substrate-mediated gene delivery, J Gene Med 2008, 10, 1334–1342.
35. Chen S, Zhang XZ,Cheng SX*, Zhuo RX, Gu ZW, Functionalized amphiphilic hyperbranched polymers for targeted drug delivery, Biomacromolecules 2008, 9, 2578-2585.
36. Yu CY, Zhang XC, Zhou FZ, Zhang XZ, Cheng SX*, Zhuo RX*, Sustained release of antineoplastic drugs from chitosan-reinforced alginate microparticle drug delivery systems, Inter J Pharm 2008, 357, 15-21.
37. Zhou YX, Li SL, Fu HL, Cheng SX*, Zhang XZ, Zhuo RX, Fabrication and in vitro drug release study of microsphere drug delivery systems based on amphiphilic poly-α,β-[N-(2-hydroxyethyl)-L-aspartamide]-g-poly(L-lactide) graft copolymers, Colloids Surf B: Biointerf 2008, 61, 164-169.
38. Fu HL, Cheng SX*, Zhang XZ, Zhuo RX, Dendrimer/DNA complexes encapsulated in a water soluble polymer and supported on fast degrading star poly(DL-lactide) for localized gene delivery, J Control Release 2007, 124, 181-188.
39. Fu HL, Zou T, Cheng SX*, Zhang XZ, Zhuo RX, Cholic acid functionalized star poly(DL-lactide) for promoting cell adhesion and proliferation, J Tissue Eng Regen Med 2007, 1, 368-376.
40. Zhang H, Tong SY, Zhang XZ, Cheng SX*, Zhuo RX, Li H, Novel solvent-free methods for fabrication of nano- and microsphere drug delivery systems from functional biodegradable polymers, J Phys Chem C 2007, 111, 12681-12685.
41. Zou T, Li SL, Zhang XZ, Wu XJ, Cheng SX*, Zhuo RX*, Synthesis and characterization of a biodegradable amphiphilic copolymer based on branched poly(ε-caprolactone) and poly(ethylene glycol), J Polym Sci A Polym Chem 2007, 45, 5256-5265.
42. Zou T, Li SL, Cheng SX*, Zhang XZ Zhuo RX*, Fabrication and in vitro drug release of drug-loaded star oligo/poly(DL-lactide) microspheres made by novel ultrasonic dispersion method, J Biomed Mater Res A 2007, 83A, 696-702.
43. Zou T, Li SL, Hu ZY, Cheng SX*, Zhuo RX, Synthesis and properties of star oligo/poly(trimethylene carbonate)s with cholic acid moieties as cores, J Biomater Sci Polym Edn 2007, 18, 519-530.
44. Fu HL, Yu L, Zhang H, Zhang XZ, Cheng SX*, Zhuo RX, Synthesis of novel cholic acid functionalized branched oligo/poly(ε-caprolactone)s for biomedical applications, J Biomed Mater Res A 2007, 81A, 186-194.
45. Zou T, Cheng SX*, Zhang XZ, Zhuo RX*, Novel cholic acid functionalized star oligo/poly(DL-lactide)s for biomedical applications, J Biomed Mater Res B Appl Biomater 2007, 82B, 400-407.
46. Miao ZM, Cheng SX*, Zhang XZ, Zhuo RX*, Study on drug release behaviors of poly-α,β-[N-(2-hydroxyethyl)-L-aspartamide]-g-poly(ε-caprolactone) nano- and microparticles, Biomacromolecules 2006, 7, 2020-2026.
47. Wan T, Liu Y, Yu JQ, Chen S, Li F, Zhang XZ, Cheng SX*, Zhuo RX, Synthesis and characterization of star oligo/poly(2,2-dimethyltrimethylene carbonate)s containing cholic acid moiety, J Polym Sci A Polym Chem 2006, 44, 6688-6696.
48. Yu L, Zhang H, Cheng SX*, Zhuo RX, Li H, Study on the drug release property of cholesteryl end-functionalized poly(ε-caprolactone) microspheres, J Biomed Mater Res B Appl Biomater 2006, 77B, 39-46.
49. Zou T, Li F, Cheng SX*, Zhuo RX, Synthesis and characterization of end-capped biodegradable oligo/poly(trimethylene carbonate)s, J Biomater Sci Polym Edn 2006, 17, 1093-1106.
50. Wan T, Zou T, Cheng SX*, Zhuo RX, Synthesis and characterization of biodegradable cholesteryl end-capped polycarbonates, Biomacromolecules 2005, 6, 524-529.
51. Zhang L, Wang QR, Jiang XS, Cheng SX*, Zhuo RX, Studies on functionalization of poly(ε-caprolactone) by cholesteryl moiety, J Biomater Sci Polym Edn 2005, 16, 1095-1108.
52. Zou T, Cheng SX*, Zhuo RX, Synthesis and enzymatic degradation of end-functionalized biodegradable polyesters, Colloid and Polym Sci 2005, 283, 1091-1099.
53. Zhang L, Peng T, Cheng SX*, Zhuo RX, Destabilization of liposomes by uncharged hydrophilic and amphiphilic polymers, J Phys Chem B 2004, 108, 7763-7770.
54. Cheng SX, Zhang JT, Zhuo RX, Macroporous poly(N-isopropylacrylamide) hydrogels with fast response rates and improved protein release properties, J Biomed Mater Res 2003, 67A, 96-103.
55. Cheng SX, Miao ZM, Wang LS, Zhuo RX, Synthesis and characterization of novel biodegradable copolymers of 5-benzyloxy-1,3-dioxan-2-one and glycolide, Macromol Rapid Commun 2003, 24, 1066-1069.
56. Cheng SX, Chung TS, Wang R, Vora RH, Gas-sorption properties of 6FDA-durene/1,4-phenylenediamine (pPDA) and 6FDA-durene/1,3-phenylenediamine (mPDA) copolyimides, J Appl Polym Sci 2003, 90, 2187-2193.
57. Cheng SX, Chung TS, Investigation of the effect of an ether moiety on the liquid crystallinity by thin film polymerization, Macromol Chem Phys 2002, 203, 122-128.
58. Cheng SX, Chung TS, Effect of a fluorine lateral moiety on the liquid crystallinity of wholly aromatic polyester-amides, Polymer 2002, 43, 7433-7441.
59. Cheng SX, Chung TS, Dynamic responses of a thermotropic main-chain liquid crystalline polyester during polymerization under electric fields, J Phys Chem B 2000, 104, 10506-10512.
60. Cheng S X, Chung TS, Configuration effects of ortho, meta and para linkages on liquid crystallinity during thin film polymerization of poly(ester-amide)s, J Polym Sci B Polym Phys 2000, 38, 2221-2231.
61. Cheng SX, Chung TS, Phase separation and coalescence, annihilation of liquid crystal textures during polymerization of main-chain liquid crystalline polyesters, J Phys Chem B 1999, 103, 4923-4932.
62. Cheng SX, Chung TS, Mullick S, Novel thin-film polymerization and time evolution of liquid crystal texture during polymerization, Chem Eng Sci 1999, 54, 663-674.
63. Cheng SX, Chung TS, Mullick S, Effects of monomer structures on evolution of liquid-crystal texture and crystallization during thin-film polymerization, J Polym Sci B Polym Phys 1999, 37, 3084-3096.
64. Cheng SX, Bai RK, Zou YF, Pan CY, Electro-optical properties of polymer dispersed liquid crystal materials, J Appl Phys 1996, 80, 1991-1995.
