中文別名 N,N-二甲基-10H-吩噻嗪-10-丙胺鹽酸鹽,英文名稱 Promazine hydrochloride,英文別名 N,N-Dimethyl-10H-phenothiazine-10-propanamine hydrochloride。
基本介紹
- 中文名:鹽酸丙嗪
- CASRN:53-60-1
- EINECS:200-179-7
- 分子式:C17H20N2SHCL
簡介
物質毒性
編號 | 毒性類型 | 測試方法 | 測試對象 | 使用乃捆阿劑凶束定灑量 | 毒性作用 |
1 | acute | Oral | Human | 20 mg/kg/D-I | 1.行為毒性捆驗想Behavioral - general anesthetic 2.行為毒性Behavioral - tremor 3.行為毒性Behavioral - antipsychotic |
2 | acute | Oral | Rodent - rat | 400 mg/kg | 1.Details of toxic effects not reported other than lethal dose value |
3 | acute | Intraperitoneal | Rodent - rat | 356 mg/kg | 1.眼毒付估請性棗謎采殼Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) 2.行為毒性Behavioral - changes in motor activity (specific assay) 3.肺部、胸部或者呼吸毒性Lungs, Thorax, or Respiration - respiratory depression |
4 | acute | Intravenous | Rodent - rat | 29 mg/kg | 1.Details of toxic effects not reported other than lethal dose value |
5 | acute | Subcutaneous | Rodent - mouse | 300 mg/kg | 1.Details of toxic effects not reported other than lethal dose value |
6 | acute | Intravenous | Rodent - mouse | 38 mg/kg | 1.Details of toxic effects not reported other than lethal dose value |
7 | acute | Intramuscular | Rodent - mouse | 28 mg/kg | 1.Details of toxic effects not reported other than lethal dose value |
8 | acute | Intramuscular | Mammal - dog | 4400 ug/kg | 1.Details of toxic effects not reported other than lethal dose value |
9 | acute | Intravenous | Rodent - rabbit | 21 mg/kg | 1.Details of toxic effects not reported other than lethal dose value |