基本介紹
研究方向,個人榮譽,人物經歷,教育經歷,工作經歷,主講課程,研究領域,學術成果,
研究方向
主要研究方向包括合理藥物設計,蛋白結構-功能關係,藥物信息學等。
個人榮譽
人物經歷
教育經歷
工作經歷
2006年3月-2007年2月,在義大利Insubria大學結構與功能生物學系進行博士後研究;
2007年3月-2008年6月,在香港科技大學和北京大學做博士後研究,合作導師:吳雲東院士;
2008年6月-,蘭大萃英人才計畫引進人才,蘭州大學藥學院教授,藥物化學專業博士生導師。
主講課程
博士生課程:《計算機輔助藥物設計》、《藥物設計學》、《藥物信息學》。
研究領域
現今其主要研究方向包括合理藥物設計,蛋白結構-功能關係,藥物信息學等。
學術成果
在相關領域的SCI源期刊如Molecular Pharmaceutics, Journal of Chemical Information and Computer Science, Chemical Research in Toxicology, Journal of Computer-Aided Molecular Design, Journal of Physical chemistry B, Combinatorial Chemistry and High Throughput Screening等雜誌上已發表論文50餘篇,其中第一作者19篇,被引用250餘次。
In Silico Identification of the Potential Drug Resistance Sites over 2009 Influenza A (H1N1) Virus Neuraminidase
Author(s): Liu, HX; Yao, XJ; Wang, CQ, et al.
Source: MOLECULAR PHARMACEUTICS Volume: 7 Issue: 3 Pages: 894-904 Published: 2010
Molecular Basis of the Interaction for an Essential Subunit PA-PB1 in Influenza Virus RNA Polymerase: Insights from Molecular Dynamics Simulation and Free Energy Calculation
Author(s): Liu, HX; Yao, XJ
Source: MOLECULAR PHARMACEUTICS Volume: 7 Issue: 1 Pages: 75-85 Published: 2010
The Applications of Machine Learning Algorithms in the Modeling of Estrogen-Like Chemicals
Author(s): Liu, HX; Yao, XJ; Gramatica, P
Source: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING Volume: 12 Issue: 5 Pages: 490-496 Published: 2009
Optimal conditions for hydropriming lucerne seeds
Author(s): Liu, HX; Guo, ZG; Wang, YR
Source: NEW ZEALAND JOURNAL OF AGRICULTURAL RESEARCH Volume: 51 Issue: 1 Pages: 69-75 Published: 2008
Study on adsorption behavior of volatile and semivolatile organic vapors to air-dry soils based on QSPR methods
Author(s): Liu, HX; Yao, XJ; Liu, MC, et al.
Source: ENVIRONMENTAL POLLUTION Volume: 147 Issue: 1 Pages: 41-49 Published: MAY 2007
Prediction of gas-phase reduced ion mobility constants (K-0) based on the multiple linear regression and projection pursuit regression
Author(s): Liu, HX; Yao, XJ; Liu, MC, et al.
Source: TALANTA Volume: 71 Issue: 1 Pages: 258-263 Published: JAN 15 2007
The accurate QSPR models to predict the bioconcentration factors of nonionic organic compounds based on the heuristic method and support vector machine
Author(s): Liu, HX; Yao, XJ; Zhang, RS, et al.
Source: CHEMOSPHERE Volume: 63 Issue: 5 Pages: 722-733 Published: MAY 2006
Prediction of retention in micellar electrokinetic chromatography based on molecular structural descriptors by using the heuristic method
Author(s): Liu, HX; Yao, XJ; Liu, MC, et al.
Source: ANALYTICA CHIMICA ACTA Volume: 558 Issue: 1-2 Pages: 86-93 Published: FEB 3 2006