《G Protein-Coupled Receptors》是2010年出版的圖書,作者是 Poyner, David R.; Wheatley, Mark。
基本介紹
- 中文名:G Protein-Coupled Receptors
- 作者: Poyner, David R.; Wheatley, Mark
- 出版時間:2010年3月
- 頁數:310 頁
- ISBN:9780470749142
- 類別:圖書
- 定價:795 元
《G Protein-Coupled Receptors》是2010年出版的圖書,作者是 Poyner, David R.; Wheatley, Mark。
《G Protein-Coupled Receptors》是2010年出版的圖書,作者是 Poyner, David R.; Wheatley, Mark。內容簡介 G-Protein Coupled Receptors (GPCRs) are not only the largest protein family in the human genome but are also the ...
MRGF(MAS-related GPR, member F)是與小鼠同源的一種人類G蛋白偶聯受體(G protein-coupled receptors,GPCRs),作為受體蛋白MRGF有G蛋白偶聯受體活性和信號傳導活性,但作為一種孤兒GPCRs(orphan GPCRs,oGPCRs),MRGF基因的研究...
G蛋白偶聯受體(G protein coupled receptors,GPCR)有800多個成員,組成了細胞膜最大的受體家族,這些受體控制了很多基本的生理過程,比如神經傳遞,激素、酶的釋放,炎症和血壓調節等等[[14]]。GRK-2(G protein-coupled receptor kinase-...
這些激素刺激黑色素細胞表面的G蛋白耦合性受體(G-protein coupled receptors),之後訊號輾轉進入細胞內部。黑色皮質素能使色素分散,而褪黑激素與黑色素凝集激素則使色素集中。許多魚類與蛙類的黑色皮質素、褪黑激素與黑色素凝集激素的受體...
protein kinase,tpk)完成的,tpk特異的抑制因子除莠黴素a可以阻礙細胞的黏附[11]。在cd34分子參與下,hsc持續表達g蛋白耦聯受體(gprotein coupled receptors,gpcrs):cxcr4、cyslt1、s1p、s1p1等[12],促使細胞發生趨化、黏著從而...
G Protein-Coupled Receptors(G蛋白偶聯受體)G Proteins and Effectors(G蛋白和效應物)Growth Factor Receptors(生長因子受體)Growth Hormone(GH)(生長激素)Growth Hormone-Binding Proteins(生長激素結合蛋白)Guanylyl Cyclase ...
GTP Hydrolysis by Gα and Its Regulation by RGS Proteins Gβγ Dimers GPR/GoLoco Motifs Gα–GPCR Interactions Section B: Vertical Receptors Chapter 23: Structure and Function of G-Protein-Coupled Receptors: Lessons from...
眾所周知,GPCR(G蛋白偶聯受體,G-protein coupled receptors)作為人類基因組編碼的最大類別膜蛋白超家族,有800多個家族成員,與人體生理代謝幾乎各個方面都密切關聯。它們的構象高度靈活,調控非常複雜,天然豐度很低,起初非常難以研究。
3. Youyong Li, Tingjun Hou*, William A. Goddard III*, Molecular modeling of structure-function of G Protein-Coupled Receptors with applications for drug design, Current Medicinal Chemistry, 2010, 17, 1167-1180.4. ...
Intraneuronal trafficking of G-protein-coupled receptors in vivo Véronique Bernard, Marion Décossas, Isabel Liste and Bertrand Free radicals and aging Gustavo Barja自由基與衰老 A novel role for abscisic acid emerges from ...
10. Tan, Liang; Yan, Wenzhong; McCorvy, John D.*; Cheng, Jianjun*. Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure-Functional Selectivity Relationships (SFSRs) and Therapeutic Potential. Journal of ...
《Structure of a bd oxidase indicates similar mechanisms for membrane-integrated oxygen reductases》《Cell-free synthesis of isotopically labelled peptide ligands for the functional characterization of G protein-coupled receptors》...
14. Jastrzebska Beata, Salom David, Jin Hui, Cao Pengxiu, Sun Wenyu, Palczewski Krzysztof, Feng Zhaoyang. (2013) Expression of mammalian Gprotein-coupled receptors in Caenorhabditis elegans. Methods ...
6. Katidou, M., Grosmaitre, X., Lin, J., Mombaerts, P. (2018). G-protein coupled receptors Mc4r and Drd1a can serve as surrogate odorant receptors in mouse olfactory sensory neurons. Molecular and Cellular ...
13. Xin W.K., Yang X., Rich T.C., Krieg T., Barrington R., Cohen M.V., and Downey J.M. 2012. All Preconditioning-Related G Protein-Coupled Receptors Can be Demonstrated in the Rabbit Cardiomyocyte. J ...
7. Pin JP, Kniazeff J, Liu JF, Binet V, Goudet C, Rondard P, Prézeau L. (2005) Allosteric functioning of dimeric class C G-protein-coupled receptors. FEBS Journal., 272(12): 2947-2955. (IF 3.26).8. *...
8.Du C, Xie X. G protein-coupled receptors as therapeutic targets for multiple sclerosis.Cell Research, 2012, 22(7):1108-1128.9.Du C, Yang R, Song S, Wang Y, Kang J, Zhang R, Su D, Xie X. Magnesium ...
■ Zhijun Liu, Lin Geng, Ruxin Li,Xiangping He,James Q Zheng and Zuoping Xie. Frequency modulation of synchronized Ca++ spike in cultured hippocampal networks through G-Protein-coupled receptors. The Journal. of ...
21. Zhan-Chao Li, Xuan Zhou, Zong Dai, and Xiao-Yong Zou(*), Classification of G-protein Coupled Receptors Based on Support Vector Machine with Maximum Relevance Minimum Redundancy and Genetic Algorithm. BMC Bioinformatics...
(2)依託“十二五”新藥創製重大專項課題“新型G蛋白偶聯受體靶向藥物篩選體系建立及其關鍵技術研究”,圍繞與AD治療相關的G蛋白偶聯受體( G protein-coupled receptors,GPCRs),建立GPCR穩轉細胞株及其高通量篩選模型,實現G蛋白偶聯受體新藥...
Jin M, Fu P, Zhang N, Luo J, Li D, Liu M, Zhou Y,Yongqun Zhu.Crystal Structure of LGR4-Rspo1 Complex: Insights into the divergent mechanisms of ligand recognition by Leucine-rich G-protein-coupled receptors (LG...
Chen YR, Gao W, Guo XP, Ding DW, Yoshida A, Osatomi K, Yang JL*. 2018. Effects on larval metamorphosis in the mussel Mytilus coruscus of compounds that at on downstream effectors of G-protein-coupled receptors. ...
(31) Wang, J., Weng, J., Cai, Y., Penland, R., Liu, M., and Ittmann, M. (2006) The prostate specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to ...
A.A, Liu W, Roth C.B, Griffith M.T., Katritch V, Kunken J, Xu F, Cherezov V, Hanson M.A, Stevens R.C. “Fusion Partner Toolchest for the Stabilization and Crystallization of G Protein-Coupled Receptors” ...