關國平,男,工學博士,東華大學紡織學院副教授。英國Textile Institute、中國生物材料學會/上海市生物醫學工程學會會員。Textile Research Journal、Fibers and Polymers、IEEE 國際學術會議審稿人。主要研究方向為生物醫用紡織材料及醫用材料的生物學評價。
基本介紹
- 中文名:關國平
- 出生日期:1980年8月
- 學位/學歷:工學博士
- 專業方向:生物醫用紡織材料及醫用材料的生物學評價
主講及參與課程,學習及工作經歷,研究方向,近年來承擔的科研項目,發表論著,論文,專利,專著,國內外交流與合作,
主講及參與課程
- 生物學及醫學基礎
- 生物醫用紡織品
- 紡織生物醫用材料與技術
- 紡織生物醫用材料成型與評價
- 組織工程學
- 專業前沿課
學習及工作經歷
- 2012.9至今,東華大學,副教授;
- 2011.9-2012.8,東華大學,講師;
- 2009.9-2011.8,東華大學博士後,研究方向為紡織基小口徑人造血管的製備與評價;
- 2006.9-2009.6,蘇州大學,獲紡織工程工學博士學位,研究方向為絲蛋白基生物材料;
- 2003.9-2006.6,西南大學,獲細胞生物學理學碩士學位;
- 1999.9-2003.6,西南農業大學,獲動物醫學農學學士學位;
研究方向
- 生物醫用材料的設計與製備;
- 醫用材料的生物學評價;
- 生物材料表面及界面分析、改性及細胞與分子機制的探索;
近年來承擔的科研項目
- 主持2011年國家自然科學基金青年基金資助1項,抗血栓及促內皮化混構小口徑人造血管研究,項目編號:51003014,19萬,2011.1-2013.12;
- 主持2011年東華大學中央高校基本科研業務費(追加)專項基金重點項目1項,仿真環境下絲滌小口徑人造血管與血管內皮細胞相互作用機制研究,項目編號:2011D1180118, 30萬,2011.10-2012.10;
- 主持中國博士後科學基金面上項目資助1項,3萬,編號:20100480570;
- 主持東華大學青年教師科研啟動基金項目1項,具抗凝血及促內皮化雙功能小徑人造血管的製備,2009.10-2011.09, 2萬,項目編號:101-10-0044019;
- 主持紡織面料教育部重點實驗室開放課題1項,絲滌混構小徑管狀織物的成型及其結構調控,1.5萬,2011.10-2012-10,項目編號:P1103;
- 指導上海市大學生創新計畫課題1項,絲素纖維-PET小徑人造血管的製備及其抗凝血性能研究,王銀雁,王宇驊,何南霏等,2009.4-2011.4,2萬;
- 指導上海市大學生創新計畫課題1項,真絲含量及分布對絲滌混構小口徑人造血管性能影響,胡星友,曾水林,張露瑩等,2011.6-2013.6,2萬;
- 指導上海市大學生創新計畫課題1項,人造血管水滲透性測試方法的標準化細節探索,徐睿,王義斌,何欣煜等,2012.6-2014.6,2萬;
- 作為主要研究人員申請並參與2010年上海市科學技術委員會非政府間國際合作項目1項,輔助體內血管原位再生的纖維集合體小徑人造血管,2010.7 -2012.7,15萬,項目編號:10520706600;
- 作為主要研究人員申請並參與2010年博士點基金(博導類)1項,項目編號:20100075110001,6萬,2011.1-2013.12;
- 作為主要研究人員申請並參與多層貫穿三維仿真結構的小口徑人造血管設計與成型,東華大學紡織生物醫用材料科學與技術創新引智基地2010年重點項目("111"計畫)資助,2010.09-2011.08,15萬,項目編號:B07024-SP1007;
- 家蠶細胞系的建立、篩選、鑑定及套用,“863”項目,項目編號:2004AA2Z1020;主要承擔細胞系的建立與鑑定;
- 家蠶細胞系的建立、篩選、鑑定及套用,國家自然科學基金項目,項目編號:30471312;主要承擔細胞系的建立與鑑定;
- 家蠶主要經濟性狀功能基因組與分子改良研究,國家重點基礎研究發展計畫課題(“973”課題),項目編號:2005CB121000;主要承擔細胞系的建立與鑑定、基因的克隆與功能分析;
發表論著
論文
- M. Fazley ELAHI, Guoping GUAN and Lu WANG. Improved Hemocompatibility of Silk Fibroin Fabric Using Layer-by-Layer Polyelectrolyte Deposition and Heparin Immobilization. J. App. Polym. Sci. 2014, 131,40772 (SCI)2014.4.14 DOI: 10.1002/app.40772
- M. Fazley ELAHI, Guoping GUAN and Lu WANG. Influence of layer-by-layer polyelectrolyte deposition and EDC/NHS activated heparin immobilization onto silk fibroin fabric. Materials. 2014, 7(4), 2956-2977 (SCI)收錄號000336091400028
- M. Fazley ELAHI, Guoping GUAN and Lu WANG. Hemocompatibility of surface modified silk fibroin materials: a review. Reviews on Advnanced Materials Science Journal. Reviews on Advnanced Materials Science Journal. 2014 (38) :148-159(SCI)2011年影響因子0.915,2014.2.18Vol38N2 Oct Rev. Adv. Mater. Sci.
- 關穎,關國平,楊小元,彭蕾,王璐,絲滌混構小口徑人造血管的實驗研究(一)——設計與成型,東華大學學報,2014
- 關穎,關國平,楊小元,彭蕾,王璐,絲滌混構小口徑人造血管的實驗研究(二)——結構與性能,東華大學學報,2014
- 陳肖會,關國平,王璐,環氧化合物交聯明膠水凝膠的製備及表征,生物醫學工程學進展,2014, 35(1) :18-22
- 關國平,關紅濤,王璐,韌帶損傷及人工韌帶套用與研究進展,生物醫學工程學進展,2013,34(4):234-238.
- GUAN Guo-ping(關國平),Md. Fazley Elahi, WANG Lu(王璐), SHEN Gao-tian(沈高天), CHEN Xiao-hui(陳肖會), ZHOU Hao(周浩), XU Rui(徐睿), Promoted Cytocompatibility of Silk Fibroin Fiber Vascular Graft through Chemical Grafting with Bioactive Molecules, Journal of Donghua University ( Eng. Ed. ) Vol. 30, No. 5 (2013) :362-366(EI)
- YANG Xiao-yuan(楊小元), WANG Lu(王璐), GUAN Guo-ping(關國平), GUAN Ying(關穎), KING W Martin. Preparation and mechanical performance of blended polyester/silk small diameter arterial prostheses. Journal of Donghua University ( Eng. Ed. ) Vol. 30, No. 5 (2013) :356-358(EI)
- Guoping Guan, Lu Wang, Mingzhong Li and Lun Bai, In vivo biodegradation of porous silk fibroin films implanted beneath the skin and muscle of the rat, Bio-Medical Materials and Engineering 24 (2014) 789–797(SCI)
- 高洪泉,李學敏,吳彩琴,關國平,王富軍,王璐,王克強,張紅旗,豬動脈及心臟瓣膜內皮細胞的形態學特徵,解剖學報,2013,44(4):541-546
- 李學敏,潘天岳,王璐,關國平,王克強,楊琳,張紅旗,豬頸總動脈有形成分與血管順應性的關係,復旦學報(醫學版),2013,40(4):413-418
- Elahi MF, Lu W, Guoping G, Khan F (2013) Core-shell Fibers for biomedical Applications-A Review. J Bioengineer & Biomedical Sci 3: 121. doi:10.4172/2155-9538.1000121
- Xiaoyuan Yang, Lu Wang*, Guoping Guan, Martin W. King, Yuling Li, Lei Peng, Ying Guan, Xingyou Hu. Preparation and evaluation of bicomponent and homogeneous polyester silk small diameter arterial prostheses. Journal of Biomaterials Applications. 2014, Vol 28(5) 676–687 DOI: 10.1177/0885328212472216 (SCI,二區)
- YANG Xiaoyuan, WANG Lu, GUAN Guoping, et al. What is the Optimum Cover Factor? Applied Mechanics and Materials. 2013(302), 292-297. (EI收錄)
- YANG Xiao-yuan, WANG Lu, GUAN Guo-ping, Peng Lei et al, Fabrication and mechanical evaluation of woven silk-polyester blended small diameter prototype arterial prostheses, 2012 International Forum on Biomedical Textile Materials. 216-220, 2012 (ISTP).
- Peng Lei, WANG Lu, GUAN Guo-ping, YANG Xiao-yuan et al, Degumming of woven silk/polyester prototype vascular graft, 2012 International Forum on Biomedical Textile Materials. 185-190, 2012 (ISTP).
- YANG Xiao-yuan, GUAN Guo-ping, WANG Lu, Peng Lei, WANG Yin-yan, WANG Yu-hua, ZHAN Quan, LI Yu-ling, Martin W KING, Preparation and Evaluation of Prototype of Woven Small-caliber Artificial Blood Vessels, 2011 International Forum on Biomedical Textile Materials, 2011:433-437(ISTP)
- ZHAN Quan, GUAN Guo-ping, YANG Xiao-yuan, PENG Lei, WANG Qi, WANG Lu, Robert GUIDOIN, Plasma and Ultraviolet Irradiation Initiated Grafting Treatment of PET, 2011 International Forum on Biomedical Textile Materials, 2011:194-200(ISTP)
- PENG Lei, GUAN Guo-ping, ZHAN Quan, YANG Xiao-yuan, WANG Lu, ZHOU Hao, Preliminary Study on Heparin-immobilization of Silk Fibroin Fibers. 2011 International Forum on Biomedical Textile Materials, 2011:161-165(ISTP)
- DAI Hong-qin(戴宏欽), BAI Lun(白倫), ZHAN Kui-hua(詹葵花), SUN Zi-ling(孫自玲), GUAN Guo-ping(關國平), Computer Simulation of Random Packing of Spherical Particles in Two Dimensions, Journal of Donghua University ( Eng, Ed.) 2011, Vol. 28 (1):31-34(EI)
- Guoping Guan, Lun Bai, Baoqi Zuo, Mingzhong Li, Zhengyu Wu, Yonglin Li and Lu Wang, Promoted Dermis Healing from Full-thickness Skin Defect by Porous Silk Fibroin Scaffolds (PSFSs), Bio-Medical Materials and Engineering. 2010(20) :295-308(SCI).
- Guoping Guan, Lun Bai, Baoqi Zuo, Mingzhong Li, Zhengyu Wu, Lu Wang, Yonglin Li, Distinct Tissue Responses to Porous Silk Fibroin Scaffolds (PSFSs) and Polyvinyl Alcohol (PVA) Sponges in vivo, IEEE, The 3rd International Conference on BioMedical Engineering and Informatics (BMEI 2010) and the 3rd International Congress on Image and Signal Processing (CISP 2010), 2010(4) :1668-1672 (EI).
- Guoping GUAN, Lun BAI, Baoqi ZUO, Mingzhong LI, Zilin SUN, Zhengyu WU, Neovascularization of Porous Silk Fibroin Films (PSFFs) as Dermis Substitutes Implanted in Rats, Materials Science Forum, Vols. 610-613 (2009) pp 1113-1119 (EI).
- Guoping Guan, Lun Bai, Baoqi Zuo, Mingzhong Li, Zhengyu Wu, Yonglin Li, Scaffolds Decorated by in vivo Environment Improve Cell Proliferation and Wound Healing, IEEE, The 2nd International Congress on Image and Signal Processing &The 2nd International Conference on BioMedical Engineering and Informatics, 2009(3): 1151-1156 (EI).
- Lun Bai, Baoqi Zuo, Guoping Guan, Lixing Dai, Yongzhen Chen, Zhenyu Zhou, Jianmei Xu, Zhenyu Wu: On the Growth Morphous of the Capillaries and Tissue in the Porous Silk Fibroin Films, Front.Mater.Sci.China, 2008, 2(3):266-270. (EI)
- Kui-hua Zhan, Lun Bai, Guo-ping Guan and Hong-qin Dai, Characterization of Angiogenesis during Skin Wound Repair by Porous Silk Fibroin Film, Advanced Materials Research, 2011, 175-176:181-185 (EI).
- Bai Lun, Xu Jianmei, Sun Qilong, Di Chuanxia, Zuo Baoqi, Guan Guoping, Wu Zhengyu, Density of Capillaries and the Oxygen Diffusion Model in the Porous Silk Fibroin Film, Front. Mater. Sci. China, 2007, 1(3): 237-242. (EI)
- Sun ZiLing, Bai Lun, Guan GuoPing, Zhuan KuiHua, Dai HongQin, Protein Adsorption and Biocompatibility of Porous Silk Fiboin Films, IEEE for The 2nd International Congress on Image and Signal Processing & The 2nd International Conference on BioMedical Engineering and Informatics, 2009(3): 1143-1146 (EI).
- Kuihua ZHAN, Lun BAI, Hongqin DAI, Guoping GUAN, Ziling SUN, The Models and Oxygen Distribution of Two-dimensional Capillary Network, Proceedings of the 5th China-Japan Conference on Mechatronics 2008, August 23, 2008, Atsugi, Japan (ISTP).
- 關國平,潘敏慧,魯成,一種家蠶卵巢原代細胞製作方法探索,西南農業大學學報,2006, (02): 326-328.
- 關國平,潘敏慧,陳敏,魯成,家蠶胚胎細胞系(BmE-SWU2)同工酶的研究,蠶業科學,2006, (01): 110-113.
- 謝敏,關國平,劉輝鳳,伍冬平,白倫,血管新生及絲蛋白材料血管化過程,現代生物醫學進展, 2009, 9(08): 1551-1554.
- 柴春利,錢平,關國平,徐偉,李文學,夏慶友,魯成,家蠶vasa基因的結構及表達研究,蠶業科學,2006, (04): 469-476.
專利
- 一種餐飲行業從業人員專用口罩
- 關國平,王俊梅,王璐,付譯鋆,具茶几功能的行李箱,中國發明專利,申請號:,申請日期:2014年月日;
- 關國平,沈高天,王璐,王富軍,胡星友,徐睿,黃健濤,一種管道器官澆注成型裝置及其使用方法,中國發明專利,申請號:201410218617.0,申請日期:2014年5月22日;公開號:CN 103989537,公開日:2014年8月20日;
- 關國平,王璐,沈高天,王富軍,胡星友,徐睿,黃健濤,管狀纖維集合體增強管道器官澆注成型裝置及其使用方法,中國發明專利,申請號:201410219839.4,申請日期:2014年5月22日;公開號:CN 103989538,公開日:2014年8月20日;
- 關國平,王璐,楊小元,湛權,李毓陵,彭蕾,周浩,王銀雁,一種三層機織小口徑人造血管及其製備方法,中國發明專利,申請號:201110142604.6,申請日期:2011年5月30日;公開號:CN102212918A,公開日:2011年10月12日;專利號ZL 2011 1 0142604.6
- 楊小元,關國平,周浩,王宇驊,何南霏,王璐,一種變速式水平給紗機,中國實用新型,授權專利號:ZL 2011 2 0177639.9,授權日期:2012年2月1日;
- 楊小元,王璐,周浩,關國平等,一種一體成型三層機織仿真人造血管,中國發明專利,授權專利號:ZL 2011 1 0142605.0,授權日期:2012年11月07日;
- 王璐,沈高天,林婧,關國平,王富軍,金馬汀,人造血管體外模擬彎折疲勞老化裝置及其測試方法,中國發明專利,專利號:ZL 2011 1 0049112.2,申請日期:2011年3月1日。授權公告日:2013年4月3日;
- 王璐,陳方,王文祖,尚亞峰,鄒婷,王富軍,周君梅,謝華,關國平等,一種可逐步降解的編織型輸尿管支架管及其製備方法.發明專利申請號:201110241408.4,申請日期:2011年8月。專利號:ZL 2011 1 0241408.4授權公告日:2014年04月16日
- 王璐,劉冰,林婧,王富軍,關國平,金馬汀.腔內隔絕術用人造血管扭轉疲勞模擬裝置及其測試方法,授權專利號:ZL 201210001843.4,發明專利申請號201210001843.4,申請日期:2011年1月5日,申請人:東華大學,公開號:102564877A,公開日:2012年7月11日;
- 林婧,王璐,付譯鋆,王富軍,關國平,管曉寧,宋戈,杜佳,陳基揚.微創血管支架扭轉彎折疲勞模擬裝置及其測試方法,發明專利申請號:201210546550.4,申請日期:2012年12月14日,申請人:東華大學;
- 王璐,楊小元,李毓陵,關國平,關穎.一種機織人造血管的製備方法,發明專利申請號:201210445091.0,申請日期:2012年11月8日,申請人:東華大學。發明專利公開號:CN102920531A,公開日:2013年2月13日。
- 王璐、沈高天、關國平、王富軍、金馬汀。一種管狀纖維基人造血管塗層/接枝裝置及使用方法。發明專利申請號:201310459942.1,申請日期:2013年9月27日。申請人:東華大學。發明專利公開號:CN 103498308A,公開日:2014年01月08日
專著
- 參編《生物醫用紡織品》第2章醫用紡織品的生物學基礎,主編王璐,Martin W KING,2011年11月,北京:中國紡織出版社,ISBN: 978-7-5064-7889-2;
- 參編“十二五”規劃教材《生物醫用紡織品功能設計與製備》、《生物醫用紡織品測試與評價》及《生物醫用紡織品實驗教程》,待出版。
國內外交流與合作
- Guoping Guan, Lu Wang, Mingzhong Li and Lun Bai, In vivo biodegradation of porous silk fibroin films implanted under the skin and muscle of the rat, The 2nd International Conference on Biomedical Engineering and Biotechnology (iCBEB 2013), 11-13 Oct. 2013, Wuhan.
- Guoping Guan, Md. Fazley Elahi, Lu Wang*, Gaotian Shen, Xiaohui Chen, Hao Zhou, Rui Xu, Promoted Cytocompatibility of Silk Fibroin Fiber Vascular Graft through Chemical Grafting with Bioactive Molecules, MedTex13, North Carolina State University, North Carolina State, US, May 13-15 2013
- Guoping Guan, Lu Wang, Xiaoyuan Yang, Quan Zhan, Lei Peng and Martin W. King. Fabrication and Biocompatibility Assessment of Woven Silk Fibroin and Polyester (PET) Small Diameter Prototype Vascular Prostheses. the 9th World Biomaterials Congress (WBC), June 1-5, 2012, Chengdu, China(Accepted)
- Guoping GUAN, Lu WANG, Quan ZHAN, Xiaoyuan YANG, Yuling LI, Robert GUIDOIN, Martin W. KING, Cellular compatibility and hemocompatibility of a silk fibroin-PET based small diameter vascular graft, International Conference on Fibrous Products in Medical and Health Care(FiberMed11), Tampere, Finland, June 28-30, 2011, oral presentation.
- GUAN Guoping, YANG Xiaoyuan, ZHAN Quan, WANG Lu, LI Yuling, WANG Fujun, Robert Guidoin, Martin W. KING, A Novel Silk Fibroin and PET Blended Textile for Small Diameter Vascular Graft, The Textile Institute Centenary World Conference Textiles: a Global Vision, 3 & 4 November 2010, Manchester, UK,Oral presentation;
- Guoping Guan, Lun Bai, Baoqi Zuo, Mingzhong Li, Zhengyu Wu, Lu Wang, Yonglin Li, Distinct Tissue Responses to Porous Silk Fibroin Scaffolds (PSFSs) and Polyvinyl Alcohol (PVA) Spongesin vivo,The 3International Conference on BioMedical Engineering and Informatics (BMEI 2010) and the 3International Congress on Image and Signal Processing (CISP 2010), 16-18 October 2010, Yantai, China,Oral presentation;
- 關國平,許建梅,詹葵華,戴宏欽,孫自玲,左保齊,李明忠,王富軍,王璐,白倫,一種評價生物材料體內降解速率的方法,2010 CCBM-全國生物材料大會, 4月15-18日,成都,口頭報告;
- Guan Guo Ping, Bai Lun, Xu Jian Mei, Zhan Kui Hua, Dai Hong Qin, Sun Zi Ling, A Semi-quantitive Method for Evaluating Degradation Rate of Degradable Biomaterials, The 2nd China-Europe Symposium on Biomaterials in Regenerative Medicine, 16-20th November 2009, Barcelona, Palau de la Música Catalana, el Petit Palau, Accepted as poster;
- Guoping Guan, Lun Bai, Baoqi Zuo, Mingzhong Li, Zhengyu Wu, Yonglin Li, Scaffolds Decorated byin vivoEnvironment Improve Cell Proliferation and Wound Healing,The 2International Conference on BioMedical Engineering and Informatics, 17-19 October 2009, Tianjin, China, Oral presentation;
- Guoping Guan, Lun Bai, Baoqi Zuo, Mingzhong Li, Zhengyu Wu, Yonglin Li, Distinct tissue responses to porous silk fibroin scaffolds (PSFSs) and polyvinyl alcohol (PVA) spongesin vivo, The 5th International Conference on Materials for Advanced Technologies (ICMAT 2009) and International Union of Materials Research Societies - International Conference in Asia (IUMRS-ICA 2009), 28 June-3 July 2009, Singapore, Oral representation;
- 關國平,李明忠,左保齊,吳徵宇,李永林,白倫,絲素蛋白基人工皮膚修復大鼠缺損真皮的效果觀察,第六屆全國創傷修復與組織再生會議,2008年10月,口頭報告,獲得優秀論文獎;
- Guoping GUAN, Lun BAI, Baoqi ZUO, Mingzhong LI, Zilin SUN, Zhengyu WU, Neovascularization of Porous Silk Fibroin Films (PSFFs) as Dermis Substitutes Implanted in Rats,MRS International Materials Research Conference, 2008.06, Chongqing. Oral presentation;
- International Forum on Textile Science and Engineering for Doctoral Candidates, 2006.11, Donghua University, Shanghai.