錢若燦，女，1987年7月出生，博士，華東理工大學化學與分子工程學院特聘副研究員，碩士生導師。
基本介紹
- 中文名：錢若燦
- 學位/學歷：博士
- 職業：教師
- 專業方向：單細胞分析與納米電化學分析
- 任職院校：華東理工大學化學與分子工程學院
個人經歷,研究方向,學術成果,
個人經歷
2009年南京大學化學系本科畢業。
2014年獲南京大學分析化學博士學位。
2014年-2016年在華東理工大學化學與分子工程學院從事博士後研究工作。
2016年起任華東理工大學特聘副研究員。
研究方向
主要研究方向為單細胞分析與納米電化學分析。
學術成果
圍繞單細胞內腫瘤相關分子表達及其通路開展研究，結合納米材料和生物化學感測方法，將納米電化學分析、等離激元納米光譜、雷射共聚焦顯微成像等技術聯用，並引入腫瘤相關分子的多通道檢測、成像和通路分析，從檢測原理和成像機制上實現創新，提出了螢光“關-開”靶向識別動態成像模式和“超微納米孔道”單細胞精準控制成像技術，建立了多種高選擇性、高信噪比的單細胞內腫瘤相關分子原位檢測成像及相關通路分析新方法，取得了一系列創新性成果。作為課題負責人主持國家自然科學基金青年科學基金項目一項。發表相關SCI論文24篇（IF＞5刊物19篇），他引550餘次，單篇最高引用105次。第一作者論文12篇，包括J. Am. Chem. Soc. 2篇、Angew. Chem. Int. Ed. 2篇、Anal. Chem. 2篇、Chem. Commun. 1篇；通訊作者論文3篇。其中1篇論文入選Nature Index的Research Highlight專欄。獲2016年上海市“晨光學者”稱號。
代表性文章：
(1)Ruo-Can Qian, Yue Cao, Li-Jun Zhao, Zhen Gu, Yi-Tao Long*,A two-stage dissociation system for multilayer imaging of cancer biomarker-synergic networks in single cells,Angewandte Chemie International Edition,
(2)Ruocan Qian, Yue Cao, Yi-Tao Long*, Dual-targeting nanovesicles for in situ intracellular imaging of and discrimination between wild-type and mutant p53,Angewandte Chemie International Edition,
(3)RuocanQian, Lin Ding, Liwen Yan, Manfei Lin, Huangxian Ju*, A robust probe for lighting up intracellular telomerase via primer extension to open a nicked molecular beacon, Journal of the American Chemical Society,
(4)RuocanQian, Lin Ding, Huangxian Ju*, Switchable fluorescent imaging of intracellular telomerase activity using telomerase-responsive mesoporous silica nanoparticle, Journal of the American Chemical Society,
(5)Ruo-Can Qian, Yue Cao, Yi-Tao Long*, Binary system for microRNA-targeted imaging in single cells and photothermal cancer therapy, Analytical Chemistry
(6)Ruocan Qian, Lin Ding, Liwen Yan, Manfei Lin, Huangxian Ju*, A smart vesicle kit for in situ monitoring of intracellular telomerase activity using a telomerase-responsive probe, Analytical Chemistry,
(7)Ruocan Qian, Lin Ding, Lei Bao, Shujun He, Huangxian Ju*, In situ electrochemical assay of cell surface sialic acids featuring highly efficient chemoselective recognition and a dual-functionalized nanohorn probe, Chemical Communications,
(8)Ruo-Can Qian, Jian Lv, Hao-Wen Li, and Yi-Tao Long*, Sugar-coated nanobullet: growth inhibition of cancer cells induced by metformin loaded glyconanoparticles. ChemMedChem,
(9)Ruo-Can Qian, and Yi-Tao Long*, Wearable chemosensors: a review of recent progress.ChemistryOpen,
(10)Ruocan Qian, LinDing, Huangxian Ju*, Fluorescence imaging for in situ detection of cell surface sialic acid by competitive binding of 3-(dansylamino)phenylboronic acid, Analytica Chimica Acta,
(11) Jian Lv,Ruo-Can Qian, Yong-Xu Hu, Shao-Chuang Liu, Yue Cao, Yong-Jie Zheng, Yi-Tao Long*, Raman/fluorescence dual-sensing and imaging of intracellular pH distribution, Chemical Communications,
(12)Yue-Yi Peng,Ruo-Can Qian, Mahmoud Elsayed Hafez, Yi-Tao Long*, Stochastic collision nanoelectrochemistry: a review of recent developments, Chemelectrochem,
(13)Jian Lv, Li-Jun Zhao,Ruo-Can Qian*, Yi-Tao Long, Off-on fluorescence monitoring of intracellular Agin single living cells using an Ag-responsive probe, Methods and Applications in Fluorescence,
(14)Li-Jun Zhao, Ru-Jia Yu, Wei Ma, Huan-Xing Han, He Tian,Ruo-Can Qian*, Yi-Tao Long*, Sensitive detection of protein biomarkers using silver nanoparticles enhanced immunofluorescence assay, Theranostics,
(15) Yue Cao, Yao Lin,Ruo-Can Qian*, Yi-Lun Ying*, Wei Si, Jingjie Sha*, Yunfei Chen, Yi-Tao Long*, Evidence of single-nanoparticle translocation through a solid-state nanopore by plasmon resonance energy transfer, Chemical Communications,
