谷戰軍:人物經歷,研究方向 ,主要成就, 所獲榮譽 ,人物評價,

谷戰軍，中國科學院高能物理研究所研究員，國家優秀青年基金獲得者（2018）。

基本介紹

中文名：谷戰軍
外文名：Zhanjun Gu
國籍：中國
民族：漢族
出生地：北京
畢業院校：中科院化學所
職業：教育科研工作者

人物經歷,研究方向 ,主要成就, 所獲榮譽 ,人物評價,

人物經歷

1998-2002 華中科技大學精細化工學士

2002-2007 中科院化學所物理化學博士

2007-2009 美國喬治亞大學博士後

2009.10-2016.12，中科院高能物理研究所，副研究員

2016.12-至今，中科院高能物理研究所，研究員

研究方向

主要研究方向為納米材料的可控合成及其生物效應研究。多年來一直從事新型多功能納米材料的設計合成及其在生物成像，癌症治療和納米生物安全性的研究工作。以多功能納米材料的設計合成為核心，以材料的功能化為導向，以癌症綜合治療為目的，開發出過渡金屬離子摻雜、多重核殼納米結構調控、質子插層等納米材料製備新方法，構建了一系列具有特定功能的螢光上轉換、過渡金屬硫化物/硒化物、多酸納米糰簇等新型納米粒子；針對生物納米材料的客觀需求，利用同步輻射、生物成像等手段系統研究了這些納米粒子的生物分布、轉化、代謝和清除過程，獲取理化特性對其體內過程及生物安全性的影響規律；進一步地，利用納米粒子獨特的理化性質和多藥物共輸運能力，探索了納米材料介導的熱療/化療/放療/光動力治療等多模態協同治療策略，揭示了納米材料介導的不同治療手段的協同增效機制，為最佳化納米材料介導的腫瘤綜合治療提供了依據，同時也為臨床最佳化腫瘤綜合治療策略提供了借鑑。

主要成就

代表性論文

[1] Gu Zhanjun, Zhu Shuang, Yan Liang, Zhao Feng, Zhao Yuliang.Graphene-Based Smart Platforms for Combined Cancer Therapy. Advanced Materials. 2019,31,9:1800662.

[2] Gu Zhanjun, Yan Liang, Tian Gan, Li Shoujian, Chai Zhifang, Zhao Yuliang. Recent Advances in Design and Fabrication of Upconversion Nanoparticles and Their Safe Theranostic Applications. Advanced Materials. 2013;25:3758-3779.

[3] Xie Jiani, Gong Linji, Zhu Shuang, Yong Yuan, Gu Zhanjun, Zhao Yuliang. Emerging Strategies of Nanomaterial-Mediated TumorRadiosensitization. Advanced Materials. 2019,31,1802244.

[4] Yan Liang, Zhao Feng, Wang Jing, Zu Yan, Gu Zhanjun*, ZhaoYuliang*. A Safe-by-Design Strategy towards Safer Nanomaterials inNanomedicines. Advanced Materials. 2019,1805391.

[5] Du Zhen, Zhang Xiao, Guo Zhao, Xie Jiani, Dong Xinghua, Zhu Shuang, Du Jiangfeng, Gu Zhanjun, Zhao Yuliang. X-Ray-Controlled Generation of Peroxynitrite Based on Nanosized LiLuF₄:CeScintillators and their Applications for Radiosensitization. Advanced Materials. 2018,1804046.

[6] Guo Zhao, Zhu Shuang, Yong Yuan, Zhang Xiao, Dong Xinghua, Du Jiangfeng, Xie Jiani, Wang Qing, Gu Zhanjun, Zhao Yuliang. Synthesis of BSA-Coated BiOI@Bi₂S₃ Semiconductor HeterojunctionNanoparticles and Their Applications for Radio/Photodynamic/PhotothermalSynergistic Therapy of Tumor. Advanced Materials. 2017;29,1704136.

[7] Du Jiangfeng, Gu Zhanjun, Yan Liang, Yong Yuan, Yi Xuan, Zhang Xiao, Liu Jing, Wu Renfei, Ge Cuicui, Chen Chunying, Zhao Yuliang. Poly(Vinylpyrollidone)- and Selenocysteine-Modified Bi₂Se₃Nanoparticles Enhance Radiotherapy Efficacy in Tumors and PromoteRadioprotection in Normal Tissues. Advanced Materials. 2017;29,1701268.

[8] Tian Gan, Zhang Xiao, Gu Zhanjun, Zhao Yuliang. Recent Advances in Upconversion Nanoparticles-BasedMultifunctional Nanocomposites for Combined Cancer Therapy. Advanced Materials. 2015;27:7692-7712.

[9] Zhong Yeteng, Tian Gan, Gu Zhanjun, Yang Yijun, Gu Lin, Zhao Yuliang, Ma Ying, Yao Jiannian. Elimination of Photon Quenchingby a Transition Layer to Fabricate a Quenching-Shield Sandwich Structure for800 nm Excited Upconversion Luminescence of Nd-SensitizedNanoparticles. Advanced Materials. 2014;26:2831-2837.

[10]Tian Gan, Gu Zhanjun, Zhou Liangjun, Yin Wenyan, Liu Xiaoxiao, Yan Liang, Jin Shan, Ren Wenlu, Xing Gengmei, Li Shoujian, Zhao Yuliang. Mn Dopant-ControlledSynthesis of NaYF₄:Yb/Er Upconversion Nanoparticles for in vivoImaging and Drug Delivery. Advanced Materials. 2012;24:1226-1231.

[11] Wang Xin, Guo Zhao, Zhang Chenyang, Zhu Shuang, Li Lele, Gu Zhanjun*, Zhao Yuliang. Ultrasmall BiOI Quantum Dots with Efficient Renal Clearance for EnhancedRadiotherapy of Cancer. Advanced Science. 2020;0:1902561.

[12] Zhang Xiao, Du Jiangfeng, Guo Zhao, Yu Jie, Gao Qin, Yin Wenyan, Zhu Shuang, Gu Zhanjun*, Zhao Yuliang*. Efficient Near-Infrared Light Triggered NitricOxide Release Nanocomposites for Sensitizing Mild Photothermal Therapy. Advanced Science. 2019,6,3,1801122.

[13] Zhu Shuang, Gong Linji, Li Yijian, XuHaiwei*, Gu Zhanjun*, Zhao Yuliang. Safety Assessment of Nanomaterials to Eyes: An Important but Neglected Issue. Advanced Science. 2019;0:1802289.

[14] Zhang Xiao, Tian Gan, Yin Wenyan, Wang Liming, Zheng Xiaopeng, Yan Liang, Li Jinxia, Su Haoran, Chen Chunying, Gu Zhanjun, Zhao Yuliang. Controllable Generation of Nitric Oxide by Near-Infrared-SensitizedUpconversion Nanoparticles for Tumor Therapy. Advanced Functional Materials. 2015;25:3049-3056.

[15] Gu Zhanjun, Paranthaman M. Parans, Xu Jun, Pan Zhengwei. Aligned ZnO Nanorod Arrays Grown Directly on Zinc Foils and Zinc Spheres by a Low-Temperature Oxidization Method. ACS Nano. 2009;3:273-278.

[16] Dong Xinghua, Cheng Ran, Zhu Shuang, Liu Huimin, Zhou Ruyi, Zhang Chenyang, Chen Kui, Mei Linqiang, Wang Chengyan, Su Chunjian, Liu Xiangfeng*, Gu Zhanjun*, Zhao Yuliang*. A Heterojunction Structured WO_2.9-WSe₂Nanoradiosensitizer Increases Local Tumor Ablation and Checkpoint BlockadeImmunotherapy upon Low Radiation Dose. ACS Nano. 2020.

[17] Wang Xin, Zhang Chenyang, Du Jiangfeng, DongXinghua, Jian Shan*, Yan Liang*, Gu Zhanjun*, Zhao Yuliang. Enhanced Generation of Non-Oxygen Dependent FreeRadicals by Schottky-Type Heterostructures of Au-Bi₂S₃ Nanoparticles via X-Ray-Induced Catalytic Reaction for Radiosensitization. ACS Nano. 2019,13,5,5947-5958.

[18] Yong Yuan, Zhang Chunfang, Gu Zhanjun, Du Jiangfeng, Guo Zhao, Dong Xinghua, Xie Jiani, Zhang Guangjin, LiuXiangfeng, Zhao Yuliang. Polyoxometalate-based radiosensitization platform for treating hypoxic tumors by attenuating radioresistance and enhancing radiation response. ACS Nano. 2017;11:7164-7176.

[19] Yin Wenyan, Yu Jie, Lv Fengting, Yan Liang, Zheng Li Rong, Gu Zhanjun, Zhao Yuliang. Functionalized Nano-MoS₂with Peroxidase Catalytic and Near-Infrared Photothermal Activities for Safe and Synergetic Wound Antibacterial Applications. ACS Nano. 2016;10:11000-11011.

[20] Liu Jing, Zheng Xiaopeng, Yan Liang, Zhou Liangjun, Tian Gan, Yin Wenyan, Wang Liming, Liu Ying, Hu Zhongbo, Gu Zhanjun, Chen Chunying, Zhao Yuliang. Bismuth Sulfide Nanorodsas a Precision Nanomedicine for in Vivo Multimodal Imaging-Guided PhotothermalTherapy of Tumor. ACS Nano. 2015;9:696-707.

[21]Yong Yuan, Cheng Xiaju, Bao Tao, Zu Mian, YanLiang, Yin Wenyan, Ge Cuicui, Wang Dongliang, Gu Zhanjun, Zhao Yuliang. Tungsten Sulfide Quantum Dots as Multifunctional Nanotheranostics for In Vivo Dual-ModalImage-Guided Photothermal/Radiotherapy Synergistic Therapy. ACS Nano. 2015;9:12451-12463.

[22]Yin Wenyan, Yan Liang, Yu Jie, Tian Gan, Zhou Liangjun, Zheng Xiaopeng, Zhang Xiao, Yong Yuan, Li Juan, Gu Zhanjun, ZhaoYuliang. High-Throughput Synthesis of Single-Layer MoS₂Nanosheets as a Near-Infrared Photothermal-Triggered Drug Delivery for Effective Cancer Therapy. ACS Nano. 2014;8:6922-6933.