李婷婷 博士，研究員、博士生導師、PI，現為北京大學基礎醫學院醫學信息學系研究員、長聘副教授；國家傑出青年科學基金項目獲得者。
李婷婷的主要研究方向為生物大分子凝聚體組成及動態調控的計算解析。在PNAS、Genome Biology、Nucleic Acids Research等期刊發表SCI論文40餘篇。作為課題負責人承擔國家重點研發計畫蛋白質專項，作為負責人承擔國家自然科學基金4項，作為骨幹參加973計畫等國家級課題3項。
基本介紹
人物經歷,研究方向,社會任職,研究論文,
人物經歷
1999.9-2003.7 西安交通大學自動化專業 學士
2003.9-2009.1 清華大學 生物信息學專業博士，導師為張學工教授
2009.8-2012.7 北京大學基礎醫學院醫學信息學系 講師
2012.8-2022.7 北京大學基礎醫學院醫學信息學系 副教授
2022.8-2024.1 北京大學基礎醫學院醫學信息學系 研究員、長聘副教授 博士生導師
2024.2 - 至今 博雅特聘教授、長聘正教授
研究方向
1) 生物信息學
2) 生物大分子相分離與相變
3) 蛋白質翻譯後修飾
社會任職
中國人工智慧學會生物信息學與人工生命專委會委員
中國自動化學會智慧型健康與生物信息專委會委員
中國計算機學會生物信息學專委會委員、生物物理學會生物大分子相分離與相變分會委員
研究論文
1. Zhaoming Chen#, Chao Hou#, Liang Wang#, Chunyu Yu, Taoyu Chen, Boyan Shen, Yaoyao Hou, Pilong Li*, Tingting Li*; Screening Membraneless Organelle Participants with Machine Learning Models that Integrate Multimodal Features; PNAS, 2022;119:e2115369119.
2. Fugang Duan#, Yifan Wang#, Taoyu Chen#, Zhu Zhu#, Meng Yu, Hui Dai, Shangen Zheng, Yinying Lu*, Tingting Li*, Xiaoyan Qiu*; A novel strategy for identifying biomarker in serum of patient with COVID-19 using immune complex; Signal Transduction and Targeted Therapy, 2022;7:63.
3. Minglei Shi#*, Kaiqiang You#, Taoyu Chen, Chao Hou, Zhengyu Liang, Mingwei Liu, Jifeng Wang, Taotao Wei, Jun Qin, Yang Chen*, Michael Q Zhang*, Tingting Li*; Quantifying the phase separation property of chromatin-associated proteins under physiological conditions using an anti-1,6-hexanediol index; Genome Biology, 2021;22(1):229.
4. Chunyu Yu#, Yunzhi Lang#, Chao Hou, Ence Yang, Xianwen Ren*, Tingting Li*; Distinctive Network Topology of Phase-Separated Proteins in Human Interactome; Journal of Molecular Biology, 2021;167292.
5. Boyan Shen#, Zhaoming Chen#, Chunyu Yu, Taoyu Chen, Minglei Shi, Tingting Li*; Computational Screening of Biological Phase-separating Proteins; Genomics, Proteomics & Bioinformatics; 2021 Feb;19(1):13-24
6. Kaiqiang You#, Qi Huang#, Chunyu Yu#, Boyan Shen, Cristoffer Sevilla, Minglei Shi, Henning Hermjakob*, Yang Chen*, Tingting Li*; PhaSepDB: a database of liquid–liquid phase separation related proteins; Nucleic Acids Research, 2020;48(D1):D354-D359.
7. Chunyu Yu, Boyan Shen, Kaiqiang You, Qi Huang, Minglei Shi, Congying Wu, Yang Chen, Chaolin Zhang, Tingting Li*; Proteome-scale analysis of phase-separated proteins in immunofluorescence images; Briefings in Bioinformatics, 2020;bbaa187.
8. Chao Hou#, Haotai Xie#, Yang Fu#, Yao Ma#, Tingting Li *; MloDisDB: a manually curated database of the relations between membraneless organelles and diseases; Briefings in Bioinformatics, 2020;bbaa271.
9. Rongting Huang#, Yuanhua Huang#, Yubin Guo#, Shangwei Ji, Ming Lu, Tingting Li*; Systematic Characterization and Prediction of Post-Translational Modification Cross-Talk between proteins; Bioinformatics; 2019,35(15):2626-2633.
10. Mengsha Tong#, Chunyu Yu#, Dongdong Zhan, Ming Zhang, Bei Zhen, Weimin Zhu, Yi Wang, Congying Wu, Fuchu He*, Jun Qin*, Tingting Li*; Molecular subtyping of cancer and nomination of kinase candidates for inhibition with phosphoproteomics: reanalysis of CPTAC ovarian cancer; EBioMedicine; 2019,40:305-317.
11. Yipeng Du*#, Hao Hu#, Saisi Qu#, Jifeng Wang, Chaoju Hua, Jialing Zhang, Peng Wei, Xiaolong He, Junfeng Hao, Pingsheng Liu, Fuquan Yang, Tingting Li *, Taotao Wei*. SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice, EBioMedicine, 2018.
12. Ying Li, Xueya Zhou, Zichao Zhai, Tingting Li*. Co-occurring protein phosphorylation are functionally associated, PLoS Computational Biology, 2017;13(5):e1005502.
13. Yipeng Du, Zichao Zhai, Ying Li, Ming Lu, Tanxi Cai, Bo Zhou, Lei Huang, Taotao Wei*, Tingting Li*. Prediction of lysine acylation by integrating multiple protein functional features, Journal of Proteome Research, 2016;15(12):4234-4244.
14. Kaili Gu#, Qiang Zhang#, Ying Yan#, Tingting Li#, Feifei Duan, Jing Hao, Xiwen Wang, Ming Shi, Daren Wu, Wenting Guo, Yangming Wang*. Pluripotency associated miR-290/302 family of microRNAs promote the dismantling of naive pluripotency. Cell Research, 2016;3:350-366.
15. Yuanhua Huang, Bosen Xu, Xueya Zhou, Ying Li, Ming Lu, Rui Jiang, Tingting Li*. Systematic characterization and prediction of post-translational modification cross-talk, Mol Cell Proteomics, 2015;14:761-770.
