人物經歷
1987年獲得南開大學學士學位;
1994於美國印第安納大學醫學院獲得生物化學博士學位;
1995年受聘於美國Avantis製藥公司任Sr.Research Scientist;
1998-2001年於杜克大學從事癌症與免疫T細胞信號轉導研究;
2002年回國至今為南開大學特聘教授、博士生導師;天津市特聘教授,教育部新世紀優秀人才獲得者。
研究方向
T細胞激活與凋亡信號轉導機制;病毒蛋白與宿主免疫分子作用機制。
學術論文
1.周卓,尹潔,竇植洵,唐鈞,張翠竹,曹又佳. The calponin homology domain of Vav1 associates with calmodulin and is prerequisite to T cell antigen receptor-induced calcium release in Jurkat T lymphocytes. JOURNAL OF BIOLOGICAL CHEMISTRY 282-32-23737-23744. 2007-1-1
2.賈雲芳; 秦 明; 張宏凱; 牛文成; 李 蕭; 王立凱; 李 欣; 白雲鵬; 曹又佳;馮喜增* . Label-free biosensor: A novel phage-modified light addressable potentiometric sensor system for cancer cell monitoring. BIOSENSORS & BIOELECTRONICS 22-12-3261-3266. 2007-1-1
3.張翠竹,唐鈞,謝佳,張宏愷,李亞鵬,張傑,Verpooten D,何斌,曹又佳. A conserved domain of herpes simplex virus ICP34.5 regulates protein phosphatase complex in mammalia. FEBS Lett. 582--171-176 . 2008-1-23
4.Guo Y, Rumschlag-Booms E, Wang J, Xiao H, Yu J, Wang J, Guo L, Gao GF, Cao Y, Caffrey M, Rong L. Analysis of hemagglutinin-mediated entry tropism of H5N1 avian influenza.. Virology Journal 6-39-1-13. 2009-4-1
5.Hongkai Zhang, Xin Li,Yunpeng Bai,Ruifang Niu,Yunfang Jia,Cuizhu Zhang,Lin Zhang,Xizeng Feng and Youjia Cao. Metastatic cell detection using a phage peptide modified light addressable potentiometric sensor. Biotechnol. Appl. Biochem. 53-3-185-192. 2009-7-1
6.Verpooten D, Feng Z, Valyi-Nagy T, Ma Y, Jin H, Yan Z, Zhang C, Cao Y, He B. Dephosphorylation of eIF2{alpha} Mediated by the {gamma}134.5 Protein of Herpes Simplex Virus 1 Facilitates Viral Neuroinvasion.. JOURNAL OF VIROLOGY, 83-23-12626–12630. 2009-12-1
7.Jin H, Ma Y, Prabhakar BS, Feng Z, Valyi-Nagy T, Yan Z, Verpooten D, Zhang C, Cao Y, He B. The gamma 1 34.5 protein of herpes simplex virus 1 is required to interfere with dendritic cell maturation during productive infection.. Journal of Virology 83-10-4984-4994. 2009-5-1
8.Miao Guo, Yu Yan, Hongkai Zhang, Husheng Yan, Youjia Cao, Keliang Liu, Shourong Wan, Junsheng Huang and Wei Yue. Magnetic and pH-responsive nanocarriers with multilayer core–shell architecture for anticancer drug . Journal of Materials Chemistry 18--5104-5112. 2008-9-1
9.Cao, Y., Janssen, E.M., Duncan, A. W., Altman,A., Billadeau,D.D., and Abraham, R.T. . Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line. EMBO J. 21-18-4809-4819. 2002-9-16