卿勇(四川大學華西藥學院副教授)

卿勇(四川大學華西藥學院副教授)

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卿勇,男,博士,四川大學華西藥學院副教授。

基本介紹

  • 中文名:卿勇
  • 國籍中國
  • 畢業院校日本京都大學 
  • 學位/學歷:博士 
  • 職業:教師
  • 專業方向:分子醫學 
  • 性別:男
  • 職稱:副教授 
人物經歷,研究方向,研究課題,發表論文,

人物經歷

2004/4 - 2008/3,日本京都大學,分子醫學,博士
2002/4 - 2004/3,日本京都工藝纖維大學,套用生物學,碩士
1986/9 - 1991/7,西南醫科大學,醫學學士
2011/12 - 至今,四川大學,華西藥學院,副教授
2008/4-2010/9,日本京都大學,醫學研究科放射遺傳學研究室,教務輔佐、COE研究員

研究方向

1.以DNA損傷修復為靶向的抗腫瘤藥物開發研究
2.藥物遺傳毒性分子機制研究

研究課題

1. DNA修復缺陷系統的建立與抗腫瘤靶向藥物研究(四川大學引進人才科研啟動經費資助項目, 2012-2014, 負責人)
2. 基於UBC13缺失腫瘤細胞的Deltonin高特異毒性機制研究(國家自然科學基金,主研,批准號:81373431)
3.抗B肝病毒核苷/核苷酸類似物遺傳毒性分子機制研究

發表論文

1. Ying Liu, Xiaohua Wu*, Xiaoqing Hu, Ziyuan Chen, Hao Liu, Shunichi Takeda,Yong Qing*,Multiple repair pathways mediate cellular tolerance to resveratrol-induced DNA damage,Toxicology in Vitro,2017,42: 130–138.
2. Lei Jiang, Xiaohua Wu, Fang He, Ying Liu, Xiaoqing Hu, Shunichi Takeda, Yong Qing*, Genetic Evidence for Genotoxic Effect of Entecavir, an Anti-Hepatitis B Virus Nucleotide Analog, PLoS ONE, 2016, 11(1): e0147440.
3. Qingyi Tong, Yong Qing*, Yang Wu, Xiaojuan Hu, Lei Jiang, Xiaohua Wu*, Dioscin inhibits colon tumor growth and tumor angiogenesis through regulating VEGFR2 and AKT/MAPK signaling pathways, Toxicology and Applied Pharmacology, 2014, 281 (2): 166–173.
4. Xiaojuan Hu, Xiaohua Wu, Yunfei Huang, Qingyi Tong, Shunichi Takeda, Yong Qing*, Berberine induces double-strand DNA breaks in Rev3 deficient cells, Molecular Medicine Reports, 2014; 9(5): 1883-1888.
5. Qing-Yi Tong, Yang He, Qing-Bing Zhao, Yong Qing*, Wen Huang*, Xiao-Hua Wu*, Cytotoxicity and apoptosis-inducing effect of steroidal saponins from Dioscorea zingiberensis Wright against cancer cells, Steroids, 2012, 77(12): 1219–1227.
6. Yi Li, Zhen-ling Wang, Fang He, Yang Wu, Wen Huang, Yang He, Qing-yi Tong, Yu-quan Wei, Yong Qing*, Li Yang* and Xiaohua Wu*, TP-58, a Novel Thienopyridine Derivative, Protects Mice from ConcanavalinA-Induced Hepatitis by Suppressing Inflammation, Cellular Physiology and Biochemistry, 2012, 29(1-2): 31-40.
7. Yong Qing#, Mitsuyoshi Yamazoe#, Kouji Hirota, Donniphat Dejsuphong, Wataru Sakai, Kimiyo N. Yamamoto, Douglas K. Bishop, XiaoHua Wu, Shunichi Takeda, The Epistatic Relationship between BRCA2 and the Other RAD51 Mediators in Homologous Recombination, PLoS Genetics , 2011, 7(7): e1002148.
8. Dan Shu#, Yong Qing#, Qingyi Tong, Yang He, Zhihua Xing, Yinglan Zhao, Yi Li, Yuquan Wei, Wen Huang, Xiaohua Wu, Deltonin Isolated from Dioscorea zingiberensis Inhibits Cancer Cell Growth through Inducing Mitochondrial Apoptosis and Suppressing Akt and Mitogen Activated Protein kinase Signals, Biological & Pharmaceutical Bulletin, 2011, 34(8) : 1231–1239.
9. Qing-Yi Tong#, Yong Qing#, Dan Shu, Yang He, Ying-Lan Zhao, Yi Li, Zhen-Ling Wang, Shi-Yuan Zhang, Zhi-hua Xing, Cheng Xu, Yu-Quan Wei, Wen Huang and Xiao-Hua Wu, Deltonin, a Steroidal Saponin, Inhibits Colon Cancer Cell Growth in Vitro and Tumor Growth in Vivo via Induction of Apoptosis and Antiangiogenesis, Cellular Physiology And Biochemistry, 2011, 27(3-4): 233-242.
10. Yoshimasa Takizawa#, Yong Qing#, Motoki Takaku, Takako Ishida, Yuichi Morozumi, Takashi Tsujita, Toshiaki Kogame, Kouji Hirota, Masayuki Takahashi, Takehiko Shibata, Hitoshi Kurumizaka and Shunichi Takeda, GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination, Nucleic Acids Research, 2010, 38(15): 5059–5074.

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