丁顯廷，1984年5月出生，上海交通大學生物醫學工程學院教授，博士生導師，生物醫學工程學院分子與納米醫學平台主任，個性化醫學研究院常務副院長，民盟上海交通大學委員會副主委。
基本介紹
人物經歷,研究方向,主要成就,學術成果,承擔項目,代表性論文專著,獲獎記錄,社會任職,
人物經歷
2012年3月獲得美國加州大學洛杉磯分校（UCLA）博士學位，2013年1月進入上海交通大學任特別研究員，與美國工程院院士、美國科學促進會（AAAS）院士、台灣中央研究院院士、美國UCLA前科研副校長何志明(Chih-Ming Ho)院士共同創建上海交通大學個性化醫學研究院，並擔任研究院常務副院長。
研究方向
1. 單細胞蛋白組學技術、單細胞多組學技術
3. 痕量功能蛋白質富集、捕獲、成像的納米材料
主要成就
學術成果
丁顯廷已發表包括Science Advances, Biosensors & Bioelectronics, Biofabrication, Nature Communications, PNAS, Nature Protocols, Analytical Chemistry在內的國際期刊論文70餘篇，申請國內外發明專利30餘項。
承擔項目
丁顯廷擔任比爾.蓋茨基金會(Bill & Melinda Gates Foundation)國際重大專項負責人、國家”重大新藥創製“科技重大專項負責人、國家重點研發計畫”生物安全技術“專項負責人、科技部APEC國際合作項目負責人、軍委科技委國防創新特區第一批啟動項目負責人、國家重點研發計畫”前沿和共性技術創新“課題負責人、國家“愛滋病和病毒性肝炎等重大傳染病防治”重大科技專項課題負責人、國際人類表型組計畫課題負責人、上海市科技創新行動計畫負責人、國家自然基金項目負責人等。
代表性論文專著
1. Jingqi Dang, Hongxia Li, Lulu Zhang, Sijie Li, Ting Zhang, Shiyi Huang, Yiyang Li, Chengjie Huang, Yuqing Ke, Guangxia Shen*, Xiao Zhi* and Xianting Ding*, New Structure Mass Tag based on Ab functionalized Zr-NMOF in Mass Cytometry for Multiparameter and Sensitive Single-Cell Biomarker Interrogating, Advanced Materials, 2021, 202008297
2. Shanhe Li#, Ze Wen, Behafarid Ghalandari, Tianhao Zhou, Antony R. Warden, Ting Zhang, Peng Dai, Youyi Yu, Wenke Guo, Mofang Liu, Haiyang Xie*, and Xianting Ding*, Single-cell transfection analysis chip enables high-throughput screening and accurate profiling of exogenous gene expression in single host cells, Advanced Materials, 2021, 2101108
3. Sijia Yan#, Khan Zara Ahmad, Sijie Li, Antony R. Warden, Jing Su, Yu Zhang, Youyi Yu, Xiao Zhi, Xianting Ding*, Precoated antibody proximity extension-enhanced biomarker (PROPER) assay enables trace protein detection with single-digit accuracy, Biosensors & Bioelectronics, 2021, 183:113211
4.Sijie Li#, Shiyi Huang, Yuqing Ke, Hongjun Chen, Jingqi Dang, Chengjie Huang, Wenjia Liu, Daxiang Cui, Jinglin Wang, Xiao Zhi*, Xianting Ding*, A HiPAD Integrated with rGO/MWCNTs Nano-Circuit Heater for Visual Point-of-Care Testing of SARS-CoV-2, Advanced Functional Materials, 2021, 2100801
5.Sijia Yan#, Khan Zara Ahmad, Antony R. Warden, Yuqing Ke, Nokuzola Maboyi, Xiao Zhi, Xianting Ding*. One-pot pre-coated interface proximity extension assay for ultrasensitive co-detection of anti-SARS-CoV-2 antibodies and viral RNA, Biosensors & Bioelectronics, 2021, 193 (2021) 113535
6.Yuqing Ke#, Shiyi Huang, Behafarid Ghalandari, Sijie Li, Antony R Warden, Jingqi Dang, Lin Kang, Yu Zhang, Yunqing Wang, Yiqing Sun, Jinglin Wang, Daxiang Cui , Xiao Zhi*, Xianting Ding*, Hairpin-spacer crRNA enhanced CRISPR/Cas13a system promotes the specificity of single nucleotide polymorphisms (SNPs) identification, Advanced Science, 2021, 2003611
7.Ting Zhang#, Antony R. Warden, Yiyang Li, and Xianting Ding*, Progress and applications of mass cytometry in sketching immune landscapes, Clinical and Translational Medicine (CTM), 2020, 10(6)
8.Ting Zhang, Shanhe Li, Antony R. Warden, Behafarid Ghalandari, Hongxia Li, Xiao Zhi, Haiyang Xie*, and Xianting Ding*, A Photoclick Hydrogel for Enhanced Single-cell Immunoblotting, Advanced Functional Materials, 2020, 10, 1002: 1910739
9.Youyi Yu, Jingqi Dang, Xiao Liu, Liping Wang, Shanhe Li, Ting Zhang, Xianting Ding*, Metal-labeled Aptamers as Novel nanoprobes for Imaging Mass Cytometry Analysis, Analytical Chemistry, 2020, 92, 9, 6312-6320
10. Yu Zhang#, Antony R. Warden, Khan Zara Ahmad, Yanlei Liu, Xijun He, Minqiao Zheng, Xinlong Huo, Xiao Zhi, Yuqing Ke, Hongxia Li, Sijia Yan, Wenqiong Su, Deng Cai, Xianting Ding*. Single-Cell Microwell Platform Reveals Circulating Neural Cells as a Clinical Indicator for Patients with Blood-Brain Barrier Breakdown, Research, 2021: 9873545
11.Xiao Liu#, Weichen Song#, Brandon Yi-ning Wong, Ting Zhang, Shunying Yu, Guan Ning Lin*, Xianting Ding*, A comparison framework and guideline of clustering methods for mass cytometry data, Genome Biology, 2019, (2019) 20:297
12. Yilin Cai#, Shiyi Huang#, Zhinan Zhang*, Jiazheng Zhang, Xingyue Zhu, Xiaoxiang Chen, Xianting Ding*. Bioinspired Rotation Microneedles for Accurate Transdermal Positioning and Ultra-Minimal-Invasive Biomarker Detection with Mechanical Robustness, Research, 2022, 2022(5):1-15
13. Hongxia Li#, Antony R. Warden, Jie He, Guangxia Shen*, Xianting Ding*. Expansion Microscopy with Nine-fold Swelling (NIFS) Hydrogel Permits Cellular Ultrastructure Imaging on Conventional Microscope, Science Advances,2022, abm4003
14. Xianting Ding*, Zach Njus, Taejoon Kong, Wenqiong Su, Chih-Ming Ho and Santosh Pandey*, Effective drug combination for Caenorhabditis elegans nematodes discovered by output-driven feedback system control technique, Science Advances, 2017,3(10):eaao1254
15. Lulu Zhang#, Xiao Liu#, Xiaoxiang Chen, Antony R Warden, Youyi Yu, Baozhen Huang, Xianting Ding*. SCANCell reveals diverse inter-cluster interaction patterns in systemic lupus erythematosus across the disease spectrum, Bioinformatics, 2021, Volume 38, Issue 5, Pages 1361–1368
16.Youyi Yu#, Xin Wang#, Xiaolong Jia, Lulu Zhang, Hongxia Li, Jie He, Guangxia Sheng*, Xianting Ding*. Aptamer Probes Labeled with Lanthanide-Doped Carbon Nanodots permit Dual-Modal Fluorescence and Mass Cytometric Imaging, Advanced Science, 2021, 2102812
17.Boqian Wang#, Antony R.Warden, Xianting Ding*. The Optimization of Combinatorial Drug Therapies: Strategies and Laboratorial Platforms, Drug Discovery Today, 2021, 26 (11), pp.2646-2659
獲獎記錄
國家科技領軍人才、國家海外高層次人才、國家優秀青年科學基金、國家重點實驗室PI、求是基金會“求是傑出青年學者獎”、廣慈基金會“轉化醫學創新獎”、唐仲英基金會“仲英青年學者”、上海市“曙光計畫”學者、上海市科協“飛翔計畫”學者、上海市優秀黨外雙創人才、上海交通大學“凱原十佳教師“、世界經濟論壇（World Economic Forum, WEF）青年科學家、世界頂尖科學家論壇（World Laureates Forum, WLF）青年科學家、美國南加州中華科學家工程師協會青年科學家、微納系統與工程(Microsystems & Nanoengineering, MINE) Young Scientist Award、國際實驗室自動化與篩查協會(Society for Laboratory Automatiom and Screening, SLAS) Tony B. Academic Award、iCANX Young Scientist Award。
社會任職
中國民主同盟第十三屆中央委員會委員，民盟上海市委員，民盟上海交通大學副主委，上海市徐匯區政協委員。
中央JW科技委GF科技創新特區變革性交叉科學技術領域專家組專家委員、中國婦幼保健協會青年工作委員會醫教研產一體化協作組副組長、全國腫瘤人工智慧專業委員會委員、全國發酵工程技術工作委員會智慧型製造專業委員會委員、全國衛生產業協會實驗醫學專家委員會青年委員會委員、世界華人醫師協會前沿科技與臨床轉化專業委員會委員、上海市免疫學會免疫遺傳專業委員會常務委員、上海市藥學會藥物治療專業委員會委員、上海醫學會神經免疫學會委員、中國醫藥生物技術技術協會生物安全專業委員會委員。
擔任法國國家科研署（ANR）國際通訊評審、澳大利亞國立健康與醫學研究理事會（NHMRC）國際通訊評審、以色列科技部（MOST Israel）國際通訊評審、波蘭國家科學中心（NCN）國際通訊評審、塞爾維亞科學基金會（Science Fund of the Republic of Serbia）、UK Pancreatic Cancer Research Fund (英國慈善科研機構)、Bill & Melinda Gates Foundation（美國慈善科研機構）國際通訊評審。
