基本介紹
- 中文名：齊雪峰
- 出生日期：1977年3月
- 畢業院校：四川農業大學
- 學位/學歷：博士
- 職業：教師
- 專業方向：預防獸醫學
- 任職院校：西北農林科技大學
- 性別：男
人物經歷,研究方向,開設課程,代表論著,科研項目,社會兼職,
人物經歷
2005/09 - 2008/06畢業於四川農業大學動物醫學院預防獸醫學專業，獲得博士學位；
2002/09 - 2005/06畢業西南民族大學生命科學與技術學院預防獸醫學專業，獲得碩士學位；
1997/09 - 2001/06畢業於西南民族大學生命科學與技術學院動物醫學，獲得學士學位。
2019/01 - 至今，任職於西北農林科技大學動物醫學學院，教授；
2012/01 - 2018/12，任職於西北農林科技大學動物醫學學院，副教授；
2013/08 - 2014/09，在普渡大學（Purdue University）生物科學學院，訪問學者；
2008/06 - 2011/12任職於西北農林科技大學動物醫學學院，講師。
研究方向
獸醫微生物與免疫學，羊類疫病致病與免疫機制
開設課程
本科生:《獸醫生物製品學》；研究生《獸醫生物製品研製與套用》
代表論著
[1]Qi XF,Wang T,Xue Q,Li Z,Yang B,Wang J. MicroRNA expression profiling of goat peripheral blood mononuclear cells in response to peste des petits ruminants virus infection. Veterinary Research 2018, 49:62.
[2]Yang B,Qi XF (Co-first author),Chen Z,Chen S,Xue Q,Jia P,Wang T,Wang J. Binding and entry of peste des petits ruminants virus into caprine endometrial epithelial cells profoundly affect early cellular gene expression. Veterinary Research 2018, 49:8.
[3]Wang X,Qi XF (Co-first author),Yang B,Chen S,Wang J. Autophagy Benefits the Replication of Egg Drop Syndrome Virus in Duck Embryo Fibroblasts.Frontiers in Microbiology 2018, 9:1091.
[4] Qi XF, Qin L, Du R, Chen Y, Lei M, Deng M, Wang J*. Lipopolysaccharide Upregulated Intestinal Epithelial Cell Expression of Fn14 and Activation of Fn14 Signaling Amplify Intestinal TLR4-Mediated Inflammation. Frontiers in Cellular and Infection Microbiology 2017, 7:315.
[5] Qi XF, Zhang H, Wang Q, Wang J*. Down-regulation of cellular protein heme oxygenase-1 inhibits proliferation of avian influenza virus H9N2 in chicken oviduct epithelial cells. Journal of General Virology 2017, 99:36-43.
[6] Qi XF, Xu J, Wang Z, Wang X, Wang J*. The role of hexon in egg drop syndrome virus (EDSV) inducing apoptosis in duck embryo fibroblast cells. Research in Veterinary Science 2017,114:395-400.
[7] Qi XF, Liu C, Li R, Zhang H, Xu X, Wang J*. Modulation of the innate immune-related genes expression in H9N2 avian influenza virus-infected chicken macrophage-like cells (HD11) in response to Escherichia coli LPS stimulation. Research in Veterinary Science 2017, 111:36-42
[8] Qi XF, Tan D, Wu C, Tang C, Li T, Han X, Wang J, Liu C, Li R, Wang J*. Deterioration of eggshell quality in laying hens experimentally infected with H9N2 avian influenza virus. Veterinary Research 2016, 47:35.
[9] Qi XF, Lei M, Qin L, Xie M, Zhao D, Wang J*. Endogenous TWEAK is critical for regulating the function of mouse uterine natural killer cells in an immunological model of pregnancy loss. Immunology 2016, 148:70-82.
[10] Qi XF, Zhang H, Wang Q, Wang J* The NS1 protein of avian influenza virus H9N2 induces oxidative-stress-mediated chicken oviduct epithelial cells apoptosis. Journal of General Virology 2016, 97:3183-3192.
[11] Mingzhu Lei, Lijuan Qin, Aihua Wang, Yaping Jin, Xianjun Zhao, Xuefeng Qi*. Fn14 receptor appears as a modulator of ovarian steroid-related regulation of goat endometrial epithelial cell IL-18 expression. American Journal of Reproductive Immunology 2015,73（5）：428-436.
[12] Lijuan Qin, Mingzhu Lei, Dandan Zhao, Aihua Wang, Yaping Jin, Xuefeng Qi*. Goat uterine DBA+ leukocytes differentiation and cytokines expression respond differently to cloned versus fertilized embryos. PLoS One 2015,10(1):e0116649.
[13] Mingzhu Lei, Lijuan Qin, Dandan Zhao, Aihua Wang, Xianjun Zhao, Yaping Jin, Xuefeng Qi*. Tumor necrosis factor-like weak inducer of apoptosis regulates the phenotype and cytotoxic activity of goat uterine natural killer cells. Journal of Animal Science 2015,93(2):589-597.
[14] Xuefeng Qi, Zhichun Nan, Yaping Jin, Yanyan Qu, Xianjun Zhao, Aihua Wang. Stromal-epithelial interactions modulate the effect of ovarian steroids on goat uterine epithelial cell interleukin-18 release. Domestical Animal Endocrinology 2012;42:210-9.
[15] Xuefeng Qi, Yanyan Qu, Zhichun Yaping Jin, Xianjun Zhao, Aihua Wang. Caprine endometrial stromal cells modulate the effects of steroid hormones on cytokine secretion by endometrial epithelial cells in vitro. Reproductive Biology 2012;12:309-15.
[16] Qi, X.F., Yang, X.Y., Cheng, A.C., Wang, M.S., Zhu, D.K., Jia, R.Y., Luo, Q.H., Chen, X.Y. Intestinal mucosal immune response against virulent duck enteritis virus infection in ducklings. Research in Veterinary Science 2009, 87(2):218-225.
[17] Qi, X.F., Yang, X.Y., Cheng, A.C., Wang, M.S., Guo, Y.F., Jia, R.Y. Replication kinetics of duck virus enteritis vaccine virus in ducklings immunized by the mucosal or systemic route using real-time quantitative PCR. Research in Veterinary Science 2009, 86(1):63-67.
[18] Qi, X.F., Yang, X.Y., Cheng, A.C., Wang, M.S., Zhu, D.K., Jia, R.Y. The pathogenesis of duck virus enteritis in experimentally infected ducks: a quantitative time-course study using TaqMan PCR. Avian Pathology 2008,37(3):307-310.
[19] Qi, X.F., Yang, X.Y., Cheng, A.C., Wang, M.S., Zhu, D.K., Jia, R.Y. Quantitative analysis of virulent duck enteritis virus loads in experimentally infected ducklings. Avian Diseases 2008, 52(2):338-344.
[20] Yang XY, Qi XF (Co-first author), Cheng, A.C., Wang, M.S., Zhu, D.K., Jia, R.Y., Chen, X.Y. Intestinal mucosal immune response in ducklings following oral immunisation with an attenuated duck enteritis virus vaccine. Veterinary Journal 2010, 185(2):199-203.
[21] Qi, X.F., Bai, D.N, Zhao, X.J., Wang, A.H. Probiotic activities of lab in endometritis: Probiotic activities of three Lactic acid bacteria strains isolated from healthy bovine cervix: in vitro adherence to immortalized endometrial epithelial cells and antimicrobial properties. Journal of Animal and Veterinary Advances 2011, 10(4):484-488.
[22] Qi, X.F., Jin, Y.P., Liu, H.M., Wang, A.H., Zhzo, X.J. Microencapsulation of Lactobacillus brevis and preliminary evaluation of their therapeutic effect on the diarrhea of neonatal calf. Journal of Animal and Veterinary Advances 2011, 10(2):151-156.
[23] Qi, X.F., Wang, F., Wang, D.H., Wang, A.H., Wang, A.H., Wang, C.J., Yang, J.L., Zhao, B., Zhzo, X.J. Effect of enterotoxin on promotion of adhesion of enterotoxigenic Escherichia coli. Journal of Food, Agriculture & Environment 2011, 9(3-4):576-579.
[24] Qi, X.F., Huang, N., Zhao, B., Wang, C.J., Zhzo, X.J. Prevalence serogroup and genotypes for fimbriae and enterotoxins in Escherichia coli isolated from diarrheic piglets in western China. Journal of Swine Health and Production 2012, 20(2):290-293.
科研項目
國家自然科學基金面上項目，31572588、TWEAK對山羊uNK細胞分化和功能的調節作用及其機制、2016/01-2019/12、64萬元、在研、主持。
陝西省重點研發項目（一般項目），S2018-ZDYF-YBXM-NY-0003、奶山羊繁殖障礙疫病的綜合防治技術研究與集成示範、2018/01-2019/12、15萬元、在研、主持。
教育部留學回國科研項目，TWEAK/IL-18對山羊uNK細胞分泌調節機制、2016/01-2017/12、2.6萬元、結題、主持。
教育部直屬高校科研基本業務費重點項目，NF-κB信號通路介導uNK細胞對子宮內膜容受性的作用及分子機制研究、2013/01-2016/12、20萬、結題、主持。
國家自然科學基金青年項目，30901089、山羊胚胎與子宮內膜細胞對uNK細胞活化和分泌表達的影響、2010/01-2012/12、20萬元、結題、主持。
教育部高等學校博士學科點青年教師科研專項，20090204120011、山羊胚胎與子宮內膜細胞對CD4+CD25+Tr細胞活化和分泌表達的影響、2010/01-2012/12、3.6萬元、結題、主持。
