基本介紹
- 中文名:黃開勛
- 國籍:中國
- 民族:漢族
- 職業:博士生導師
社會兼職主要有,本科教學與研究生教育,科學研究與開發,發表論文,
社會兼職主要有
教育部科技委化學化工學部委員
湖北省硒資源開發與利用促進會理事長
本科教學與研究生教育
本科生教學:
《基礎化學》、《藥物化學導論》、《化學文獻》
研究生教學:
《蛋白質與核酸的化學》(碩士生)、《化學生物學專題》(博士生)
《藥物的分子設計與新藥研究》(博士生)
碩士研究生招生:
博士研究生招生:
無機化學(生物無機化學、納米材料的合成與生物安全性)
科學研究與開發
目前主持在研項目:⑴國家自然科學基金(20671037):硒和活性氮對胰島素信號傳導系統的調控作用及機理;⑵973項目子課題(2006CB705606A):納米材料TiO2安全性解決方案的探索;⑶益聯醫藥有限公司(境外合成課題):降鈣素口腔噴霧劑的臨床前研究。
發表論文
在國內外學術期刊發表論文100多篇,其中SCI論文60餘篇,作為副主編出版有硒的專著1本,參編專著3本,代表性論文如下:
⒈Pingtang Zhao,Jinmin Wang,Guoe Cheng,and Kaixun Huang*. Fabrication of Symmetric
Hierarchical Hollow PbS Microcrystals via a Facile Solvothermal Process. Journal of Physical
Chemistry B. 2006,110,22400-22406.
⒉Guoe Cheng,Jinmin Wang,Xiangwen Liu,Kaixun Huang*. Self-Assembly Synthesis of
Single- Crystalline Tin Oxide Nanostructures by a Poly (acrylic acid) (PAA)-Assisted
Solvothermal Process. Journal of Physical Chemistry B. 2006,110,16208-16211.
⒊Qingzhi Wu,Kaixun Huang*. Protective effect of ebselen on cytotoxicity induced by
cholestane-3 beta,3 5 alpha,6 beta-triol in ECV-304 cells. Biochimica et Biophysica
Acta- molecular and cell biology of lipids. 2006,1761: 350–359.
⒋Chen-Xiao Zhang,Kai-Xun Huang*. Mechanism of apoptosis induced by a polysaccharide,
from the loach Misgurnus anguillicaudatus (MAP) in human hepatocellular carcinoma cells.
Toxicology and Applied Pharmacology. 2006,210: 236-245.
⒌Yili Ge,Hong Peng,Kaixun Huang*. 31P-NMR study on the autophosphorylation of
insulin receptor in the plasma membrane. Analytical and Bioanalytical Chemistry. 2006,
385⑸: 834–839.
⒍Rong Tang,Hongmei Liu,Tiebing Wang,Kaixun Huang*. Mechanisms of selenium inhibition
of cell apoptosis induced by oxysterols in rat vascular smooth muscle cells. Archives of
Biochemistry and Biophysics. 2005,441: 16–24.
⒎Wen-xun Guo,Kai-xun Huang*,Rong Tang,Hui-bi Xu. Synthesis,characterization
of novel injectable drug carriers and the antitumor efficacy in mice bearing Sarcoma-180
tumor. Journal of Controlled Release. 2005,107: 513–522.
⒏Quan Chi,Tielin Wang,Kaixun Huang*. Effect of insulin nitration by peroxynitrite on
its biological activity. Biochemical and Biophysical Research Communications. 2005,
330: 791–796.
⒐Tang R,Huang KX*. Inhibiting effect of selenium on oxysterols-induced apoptosis
of rat vascular smooth muscle cells. Journal of Inorganic Biochemistry. 2004,98: 1678–1685.
⒑Wu Q,Huang K*,and Xu H. Effects of long-term selenium deficiency on glutathione
peroxidase and thioredoxin reductase activities and expressions in rat aorta. Journal of
Inorganic Biochemistry. 2003; 94⑷: 301-6