高彩吉，男，博士，華南師範大學生命科學學院教授，博士生導師。
基本介紹
- 中文名：高彩吉
- 學位/學歷：博士
- 職業：教師
- 專業方向：植物細胞生物學
- 任職院校：華南師範大學生命科學學院
個人經歷,研究方向,學術成果,榮譽獎項,
個人經歷
2016年3月~至今：華南師範大學生命科學學院（SCNU），教授（Principle Investigator）。
2012年11月~ 2016年2月：香港中文大學（CUHK），博士後研究員（Postdoctoral Researcher）。
2012年7月~ 2012年10月：香港中文大學（CUHK），助理研究員（Research Assistant）。
2008年8月~ 2012年6月：香港中文大學生命科學學院，生物學，博士。
2005年9月~ 2008年6月：華南師範大學，光學（生物物理學方向），碩士。
2001年9月~ 2005年7月：臨沂大學，生物科學，本科。
研究方向
以擬南芥和玉米為研究材料，立足植物細胞生物學研究熱點和前沿問題，結合生化、分子細胞、遺傳及各類組學手段重點開展如下研究：
植物細胞囊泡運輸及其調控植物環境適應的分子機制
植物自噬及其調控植物環境適應的分子機理
泛素化蛋白分選及液泡介導的植物蛋白降解
學術成果
霍英東教育基金會第十七屆高等院校青年科學基金，主持人。
國家自然基金面上項目：植物特有蛋白FS4調控細胞內吞作用和植物對硼元素吸收轉運的分子機制研究，主持人。
廣東省普通高校特色創新類項目，主持人。
國家自然基金面上項目：囊泡運輸調控蛋白FREE1參與植物應答ABA和鹽脅迫信號的分子機制研究，主持人。
1.Yang, C., Shen, W., Yang, L., Sun, Y., Li, X., Lai, M., Wei, J., Wang, C., Xu, Y., Li, F., Liang, S., Zhong, S., Luo, M*., andGao, C*.(2020). HY5-HDA9 Module Transcriptionally Regulates Plant Autophagy in Response to Light-to-Dark Conversion and Nitrogen Starvation.Molecular Plant
2.Li, H., Li, Y., Zhao, Q., Li, T., Wei, J., Li, B., Shen, W., Yang, C., Zeng, Y., Rodriguez, P.L., Zhao, Y., Jiang, L*., Wang, X*., andGao, C*.(2019). The plant ESCRT component FREE1 shuttles to the nucleus to attenuate abscisic acid signalling.Nature Plants
3.Zhao, Q., Shen, J.,Gao, C.,Cui, Y., Wang, Y., Cui, J., Cheng, L., Cao, W., Zhu, Y., Huang, S., Zhou, Q., Leong, C.K., Leung, K.P., Chen, X., and Jiang, L*. (2019). RST1 Is a FREE1 Suppressor That Negatively Regulates Vacuolar Trafficking in Arabidopsis.Plant Cell
4.Liu, C., Shen, W., Yang, C., Zeng, L., andGao, C*.(2018). Knowns and unknowns of plasma membrane protein degradation in plants.Plant Science
5.Gao, C.,Zhuang, X., Shen, J., and Jiang, L*. (2017). Plant ESCRT Complexes: Moving Beyond Endosomal Sorting.Trends in Plant Science
6.Shen, W., Xiao, Z., Shen, J., andGao, C*.(2017). Analysis of Golgi-Mediated Protein Traffic in Plant Cells.Methods in Molecular Biology,
7.Shen, J.,Gao, C.,Zhao, Q., Lin, Y., Wang, X., Zhuang, X., and Jiang, L. AtBRO1 Functions in ESCRT-I Complex to Regulate Multivesicular Body Protein Sorting. (2016).Molecular Plant.
8.Gao, C.,Zhao, Q., and Jiang, L. (2015). Vacuoles protect plants from high magnesium stress.Proc Natl Acad Sci USA
9.Gao, C.,Zhuang, X., Cui, Y., Fu, X., He, Y., Zhao, Q., Zeng, Y., Shen, J., Luo, M., and Jiang, L. (2015b). Dual roles of an Arabidopsis ESCRT component FREE1 in regulating vacuolar protein transport and autophagic degradation.Proc Natl Acad Sci USA
10.Woo, C.H.,Gao, C.,Yu, P., Tu, L., Meng, Z., Banfield, D.K., Yao, X., and Jiang, L. (2015). Conserved function of the lysine-based KXD/E motif in Golgi retention for endomembrane proteins among different organisms.Molecular Biology of the Cell
11.Gao, C.,Luo, M., Zhao, Q., Yang, R., Cui, Y., Zeng, Y., Xia, J., and Jiang, L. (2014). A unique plant ESCRT component, FREE1, regulates multivesicular body protein sorting and plant growth.Current Biology
12.Gao, C.,Cai, Y., Zhuang, X., and Jiang, L. (2014). Analysis of prevacuolar compartment-mediated vacuolar proteins transport.Methods in Molecular Biology,
13.Gao, C.,Cai, Y., Wang, Y., Kang, B.H., Aniento, F., Robinson, D.G., and Jiang, L*. (2014). Retention mechanisms for ER and Golgi membrane proteins.Trends in Plant Science
14.Cai, Y., Zhuang, X.,Gao, C.,Wang, X., and Jiang, L*. (2014). The Arabidopsis Endosomal Sorting Complex Required for Transport III Regulates Internal Vesicle Formation of the Prevacuolar Compartment and Is Required for Plant Development.Plant Physiology
15.Gao, C.,Yu, C.K., Qu, S., San, M.W., Li, K.Y., Lo, S.W., and Jiang, L. (2012). The Golgi-localized Arabidopsis endomembrane protein12 contains both endoplasmic reticulum export and Golgi retention signals at its C terminus.Plant Cell
Other publications
16.Zhu, D., Zhang, M.,Gao, C.,and Shen, J. (2020). Protein trafficking in plant cells: Tools and markers.Science China Life Science
17.Wang, X., Xu, M.,Gao, C.,Zeng, Y., Cui, Y., Shen, W*., and Jiang, L. (2020). The roles of endomembrane trafficking in plant abiotic stress responses.Journal of Integrative Plant Biology
18.Ge, C.,Gao, C.,Chen, Q., Jiang, L., and Zhao, Y*. (2019). ESCRT-dependent vacuolar sorting and degradation of the auxin biosynthetic enzyme YUC1 flavin monooxygenase.Journal of Integrative Plant Biology
19.Cui, Y., Cao, W., He, Y., Zhao, Q., Wakazaki, M., Zhuang, X., Gao, J., Zeng, Y.,Gao, C.,Ding, Y., Wong, H.Y., Wong, W.S., Lam, H.K., Wang, P., Ueda, T., Rojas-Pierce, M., Toyooka, K., Kang, B.H., and Jiang, L. (2019). A whole-cell electron tomography model of vacuole biogenesis in Arabidopsis root cells.Nature Plants
20.Huang, X., Zheng, C., Liu, F., Yang, C., Zheng, P., Lu, X., Tian, J., Chung, T., Otegui, M.S., Xiao, S.,Gao, C.,Vierstra, R.D., and Li, F. (2019). Genetic Analyses of the Arabidopsis ATG1 Kinase Complex Reveal Both Kinase-Dependent and Independent Autophagic Routes during Fixed-Carbon Starvation.Plant Cell
21.Yang, C., Shen, W., Chen, H., Chu, L., Xu, Y., Zhou, X., Liu, C., Chen, C., Zeng, J., Liu, J., Li, Q.,Gao, C.,Charron, J.B., and Luo, M. (2018). Characterization and subcellular localization of histone deacetylases and their roles in response to abiotic stresses in soybean.BMC Plant Biology
22.Shen, J., Zhao, Q., Wang, X.,Gao, C.,Zhu, Y., Zeng, Y., and Jiang, L. (2018). A plant Bro1 domain protein BRAF regulates multivesicular body biogenesis and membrane protein homeostasis.Nature Communications
23.Lui, N.C., Tam, W.Y.,Gao, C.,Huang, J.D., Wang, C.C., Jiang, L., Yung, W.H., and Kwan, K.M. (2017). Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin.Nature Communications
24.Gimeno-Ferrer, F., Pastor-Cantizano, N., Bernat-Silvestre, C., Selvi-Martinez, P., Vera-Sirera, F.,Gao, C.,Perez-Amador, M.A., Jiang, L., Aniento, F., and Marcote, M.J. (2017). alpha2-COP is involved in early secretory traffic in Arabidopsis and is required for plant growth.Journal of Experimental Botany
25.Cui, Y., Zhao, Q., Xie, H.T., Wong, W.S., Wang, X.,Gao, C.,Ding, Y., Tan, Y., Ueda, T., Zhang, Y., and Jiang, L. (2017). MONENSIN SENSITIVITY1 (MON1)/CALCIUM CAFFEINE ZINC SENSITIVITY1 (CCZ1)-Mediated Rab7 Activation Regulates Tapetal Programmed Cell Death and Pollen Development.Plant Physiology
26.Zhuang, X., Chung, K.P., Cui, Y., Lin, W.,Gao, C.,Kang, B.H., and Jiang, L. (2017). ATG9 regulates autophagosome progression from the endoplasmic reticulum in Arabidopsis.Proc Natl Acad Sci USA
27.Tan, X., Cao, K., Liu, F., Li, Y., Li, P.,Gao, C.,Ding, Y., Lan, Z., Shi, Z., Rui, Q., Feng, Y., Liu, Y., Zhao, Y., Wu, C., Zhang, Q., Jiang, L., and Bao, Y. (2016). Arabidopsis COG Complex Subunits COG3 and COG8 Modulate Golgi Morphology, Vesicle Trafficking Homeostasis and Are Essential for Pollen Tube Growth.PLoS Genetics12.
28.Sancho-Andres, G., Soriano-Ortega, E.,Gao, C.,Bernabe-Orts, J.M., Narasimhan, M., Muller, A.O., Tejos, R., Jiang, L., Friml, J., Aniento, F., and Marcote, M.J. (2016). Sorting Motifs Involved in the Trafficking and Localization of the PIN1 Auxin Efflux Carrier.Plant Physiology
29.Cui, Y., Shen, J.,Gao, C.,Zhuang, X., Wang, J., and Jiang, L. (2016). Biogenesis of Plant Prevacuolar Multivesicular Bodies.Molecular Plant
30.Belda-Palazon, B., Rodriguez, L., Fernandez, M.A., Castillo, M.C., Anderson, E.M.,Gao, C.,Gonzalez-Guzman, M., Peirats-Llobet, M., Zhao, Q., De Winne, N., Gevaert, K., De Jaeger, G., Jiang, L., Leon, J., Mullen, R.T., and Rodriguez, P.L. (2016). FYVE1/FREE1 Interacts with the PYL4 ABA Receptor and Mediates Its Delivery to the Vacuolar Degradation Pathway.Plant Cell
31.Zhao, Q.,Gao, C.,Lee, P., Liu, L., Li, S., Hu, T., Shen, J., Pan, S., Ye, H., Chen, Y., Cao, W., Cui, Y., Zeng, P., Yu, S., Gao, Y., Chen, L., Mo, B., Liu, X., Xiao, S., Zhao, Y., Zhong, S., Chen, X., and Jiang, L. (2015). Fast-suppressor screening for new components in protein trafficking, organelle biogenesis and silencing pathway in Arabidopsis thaliana using DEX-inducible FREE1-RNAi plants.Journal of Genetics and Genomics
32.Zhuang, X., Cui, Y.,Gao, C.,and Jiang, L. (2015). Endocytic and autophagic pathways crosstalk in plants.Current Opinion in Plant Biology
33.Zeng, Y., Chung, K.P., Li, B., Lai, C.M., Lam, S.K., Wang, X., Cui, Y.,Gao, C.,Luo, M., Wong, K.B., Schekman, R., and Jiang, L. (2015). Unique COPII component AtSar1a/AtSec23a pair is required for the distinct function of protein ER export in Arabidopsis thaliana.Proc Natl Acad Sci USA
34.Cui, Y., Zhao, Q.,Gao, C.,Ding, Y., Zeng, Y., Ueda, T., Nakano, A., and Jiang, L. (2014). Activation of the Rab7 GTPase by the MON1-CCZ1 Complex Is Essential for PVC-to-Vacuole Trafficking and Plant Growth in Arabidopsis.Plant Cell
35.Shen, J., Ding, Y.,Gao, C.,Rojo, E., and Jiang, L. (2014). N-linked glycosylation of AtVSR1 is important for vacuolar protein sorting in Arabidopsis.Plant Journal
36.Meng, W., Hsiao, A.S.,Gao, C.,Jiang, L., and Chye, M.L. (2014). Subcellular localization of rice acyl-CoA-binding proteins (ACBPs) indicates that OsACBP6::GFP is targeted to the peroxisomes.New Phytologist
37.Ma, X., Chen, Z., Hua, D., He, D., Wang, L., Zhang, P., Wang, J., Cai, Y.,Gao, C.,Zhang, X., Zhang, F., Wang, T., Hong, T., Jin, L., Qi, X., Chen, S., Gu, X., Yang, D., Pan, Q., Zhu, Y., Chen, Y., Chen, D., Jiang, L., Han, X., Zhang, Y., Jin, J., and Yao, X. (2014). Essential role for TrpC5-containing extracellular vesicles in breast cancer with chemotherapeutic resistance.Proc Natl Acad Sci USA
38.Zhuang, X., Wang, H., Lam, S.K.,Gao, C.,Wang, X., Cai, Y., and Jiang, L. (2013). A BAR-domain protein SH3P2, which binds to phosphatidylinositol 3-phosphate and ATG8, regulates autophagosome formation in Arabidopsis.Plant Cell
39.Jia, T.,Gao, C.,Cui, Y., Wang, J., Ding, Y., Cai, Y., Ueda, T., Nakano, A., and Jiang, L. (2013). ARA7(Q69L) expression in transgenic Arabidopsis cells induces the formation of enlarged multivesicular bodies.Journal of Experimental Botany
40.Cai, Y., Zhuang, X., Wang, J., Wang, H., Lam, S.K.,Gao, C.,Wang, X., and Jiang, L. (2012). Vacuolar degradation of two integral plasma membrane proteins, AtLRR84A and OsSCAMP1, is cargo ubiquitination-independent and prevacuolar compartment-mediated in plant cells.Traffic
41.Cai, Y., Jia, T., Lam, S.K., Ding, Y.,Gao, C.,San, M.W., Pimpl, P., and Jiang, L. (2011). Multiple cytosolic and transmembrane determinants are required for the trafficking of SCAMP1 via an ER-Golgi-TGN-PM pathway.Plant Journal
42.Zhang, L., Xu, Q., Xing, D.,Gao, C.,and Xiong, H. (2009). Real-time detection of caspase-3-like protease activation in vivo using fluorescence resonance energy transfer during plant programmed cell death induced by ultraviolet C overexposure.Plant Physiology
43.Zhang, L., Li, Y., Xing, D., andGao, C.(2009). Characterization of mitochondrial dynamics and subcellular localization of ROS reveal that HsfA2 alleviates oxidative damage caused by heat stress in Arabidopsis.Journal of Experimental Botany
44.Gao, C.,Zhang, L., Wen, F., and Xing, D. (2008). Sorting out the role of reactive oxygen species during plant programmed cell death induced by ultraviolet-C overexposure.Plant Signal Behav3, 197-198.
45.Gao, C.,Xing, D., Li, L., and Zhang, L. (2008). Implication of reactive oxygen species and mitochondrial dysfunction in the early stages of plant programmed cell death induced by ultraviolet-C overexposure.
榮譽獎項
2018年教育部高等學校科學研究自然科學獎二等獎（第二獲獎人）。
2012年度香港中文大學生命科學學院研究生最佳研究論文獎。
