陳文(雲南大學化學科學與工程學院副研究員)

陳文，博士，雲南大學化學科學與工程學院副研究員。

基本介紹

• 中文名：陳文
• 國籍：中國
• 畢業院校：雲南大學
• 學位/學歷：博士
• 專業方向：有機化學

人物經歷

2008年7月獲雲南民族大學理學學士學位；

2011年7月獲雲南民族大學理學碩士學位；

2014年12月獲雲南大學理學博士學位；

2015年7月至今，雲南大學工作。

教學課程

承擔多名本科生畢業論文指導工作

研究領域

複雜天然產物的不對稱全合成

學術成果

論文、專著

[11] Chen, W., Yang, X. D., Tan, W. Y., Zhang, X. Y., Liao, X. L., & Zhang, H. Total Synthesis of (−)‐Vindorosine. Angewandte Chemie International Edition,2017, 56(40):12327-12331.

[10] Wen Chen, Hongbin Zhang, Asymmetric construction of all-carbon quaternary stereocenters in the total synthesis of natural products, Science China Chemistry 2016, DOI: 10.1007/s11426-016-0055-0.

[9] Wen Chen, Jian Ren, Minshou Wang, Lingjing Dang, Xianfu Shen, Xiaodong Yang Hongbin Zhang, Iodine mediated deprotection of N-tert-butanesulfinyl amines: a functional group compatible method, Chemical Communications 2014, 50, 6259-6262.

[8] Wen Chen, Xiao-Dong Yang, Yan Li, Li-Juan Yang, Xue-Quan Wang, Gao-Lan Zhang, Hong-Bin Zhang, Design, synthesis and cytotoxic activities of novel hybrid compounds between dihydrobenzofuran and imidazole, Organic & Biomolecular Chemistry 2011, 9, 4250-4255.

[7] Wen Chen, Xiao-Yan Deng, Yan Li, Li-Juan Yang, Wei-Chao Wan, Xue-Quan Wang, Hong-Bin Zhang, Xiao-Dong Yang, Synthesis and cytotoxic activities of novel hybrid 2-phenyl-3-alkylbenzofuran and imidazole/triazole compounds, Bioorganic & Medicinal Chemistry Letters 2013, 23, 4297-4302.

[6] Wen Chen, Li-Juan Yang, Shui-Xian Ma, Xiao-Dong Yang, Bao-Min Fan, Jun Lin, Crassicauline A/β-Cyclodextrin host–guest system: Preparation, characterization, inclusion mode, solubilization and stability, Carbohydrate Polymers, 2011, 84, 1321-1328.

[5] Wen Chen, Li-Juan Yang, Yan Li, Xue-Quan Wang, Shao-Jie Wang, Wei-Chao Wan, Hong-Bin Zhang, and Xiao-Dong Yang, Novel Tricyclic Indeno[5,6-b]furan -imidazole Hybrid Compounds: Design, Synthesis and Antitumor Activity, Letters in Drug Design & Discovery 2013, 10, 561-571.

[4] Wei-Chao Wan, Wen Chen, Lan-Xiang Liu, Yan Li, Li-Juan Yang, Xiao-Yan Deng, Hong-Bin Zhang, Xiao-Dong Yang, Synthesis and cytotoxic activity of novel hybrid compounds between 2-alkylbenzofuran and imidazole, Medicinal Chemistry Research 2014, 23, 1599-1611. (共同第一作者)

[3] Shui-Xian Ma, Wen Chen, Xiao-Dong Yang, Na Zhang, Shao-Jie Wang, Lin Liu, Li-Juan Yang, Alpinetin/hydroxypropyl-cyclodextrin host-guest system: Preparation, characterization, inclusion mode, solubilization and stability, Journal of Pharmaceutical and Biomedical Analysis, 2012, 67-68: 193-200. (共同第一作者)

[2] Li-Juan Yang, Wen Chen, Shui-Xian Ma, Yun-Tao Gao, Rong Huang, Sheng-Jiao Yan, Jun Lin. Host–Guest System of Taxifolin and Native Cyclodextrin or Its Derivative: Preparation, Characterization, Inclusion Mode, and Solubilization, Carbohydrate Polymers 2011, 85, 629-637. (第一作者為導師)

[1] Li-Juan Yang, Wen Chen, Yi-Ping Luo, Gan-Peng Li, Xiao-Dong Yang, Liang Li, Lignans and ketonic compounds from Litsea chinpingensis, Biochemical Systematics and Ecology 2009, 37, 696-698. (第一作者為導師)

科研項目、成果和專利

1.鹵代吖丙啶類化合物的不對稱合成及其抗腫瘤活性研究，雲南省套用基礎研究計畫(2016FD007)，2016.9-2019.9。（負責）

2. 羊曉東，張洪彬，陳文，汪學全，楊麗娟，李良，二氫呋喃並茚烷-咪唑鹽類化合物及其製備方法，CN201210237387.3，申請時間：2012年7月9日。

3. 羊曉東，張洪彬，汪學全，陳文，李良，劉建平，2-苄基取代苯並呋喃—咪唑鹽類化合物及其製備方法，CN201210237371.2，授權時間：2014年10月15日。

學術兼職

Chemical Biology & Drug Design雜誌審稿人