人物簡介
陳學偉,男,博士,
四川農業大學特聘教授,研究員,博士生導師,四川省“百人計畫”特聘專家,四川省學術帶頭人,教育部“新世紀優秀人才”。
教育經歷
四川農業大學,茶學,1993級,學士
四川農業大學,作物遺傳育種專業,1997級,碩士
中國科學院遺傳與發育生物所,2003年,博士
研究方向
利用
遺傳學,
分子生物學,
植物病理學,
生物化學,生物信息學等多學科知識和技術手段對水稻抗病蟲害及其他重要農藝性性狀控制基因的分子克隆及分子作用機制研究,為培育高抗、高產、優質水稻品種提供理論及套用基礎。
科學研究
發表論著
1 Xuewei Chen*, Shimin Zuo , Benjamin Schwessinger, Mawsheng Chern, Patrick E. Canlas, Deling Ruan, Xiaogang zhou, Jing Wang, Arsalan Daudi, Christopher J. Petzold, Joshua L. Heazlewood and Pamela C. Ronald*. 2014 An XA21-Associated Kinase (OsSERK2) regulates immunity mediated by the XA21 and XA3 immune receptors, Molecular Plant doi:10.1093/mp/ssu003
2 Xuewei Chen, Miguel E. Vega-Sánchez, Yves Verhertbruggen, Dawn Chiniquy, Patrick E. Canlas, Alexandra Fagerström, Lina Prak, Ulla Christensen, Ai Oikawa, Mawsheng Chen, Shimin Zuo, Fan Lin, Manfred Auer, William G.T. Willats, Laura Bartley, Jesper Harholt, Henrik V. Scheller, and Pamela C. Ronald. 2012 Inactivation of OsIRX10 leads to decreased xylan content in ricestem cell walls and improved biomass saccharification. Molecular Plant 6(1): doi: 10.1093/mp/sss135.
3 Mawsheng Chern, Wei Bai, Xuewei Chen, Pamela Ronald. 2013, Reduced expression of glycolate oxidase leads to enhanced disease resistance in rice. Peer Journal 1:e28. doi: 10.7717/peerj.28.
4 Miguel E. Vega-Sánchez, Yves Verhertbruggen, Ulla Christensen, Xuewei Chen, Vaishali Sharma, Patanjali Varanasi, Stephen A. Jobling, Mark Talbot, Rosemary G. White, Michael Joo, Seema Singh, Manfred Auer, Henrik V. Scheller and Pamela C. Ronald. 2012, Loss of Cellulose Synthase-Like F6 Function Affects Mixed-Linkage Glucan Deposition, Cell Wall Mechanical Properties, and Defense Responses in Vegetative Tissues of Rice. Plant Physiology 159:56-69.
5 Xuewei Chen and Pamela C. Ronald. 2011, Innate immunity in rice. Trends in Plant Science.16:451-459.
6 Xuewei Chen, Mawsheng Chern, Patric E. Canlas, Deling Ruan, Caiying Jiang, Pamela C. Ronald. 2010, The rice XB24 ATPase promotes autophosphorylation of XA21 and inhibits XA21-mediated immunity. Proceedings of the National Academy of Sciences (Track II).107:8029-8034.
7 Xuewei Chen, Mawsheng Chern, Patric E. Canlas, Deling Ruan, Caiying Jiang, Pamela C. Ronald A conserved threonine residue in the juxtamembrane domain of the XA21 pattern recognition receptor is critical for kinase autophosphorylation and XA21-mediated immunity. 2010, Journal of Biological Chemistry. 285: 10454-10463.
8 Junjun Shang, Yong Tao, Xuewei Chen (co-first author), Yan Zou, Cailin Lei, Jing Wang, Xiaobing Li, Xianfeng Zhao, Meijun Zhang, Zhike Lu, Jichen Xu, Zhukuan Cheng, Jianmin Wan, Lihuang Zhu. 2009, Identification of a new rice blast resistance gene, Pid3, by genome-wide comparison of paired NBS-LRR genes and their pseudogene alleles between the two sequenced rice genomes. Genetics, 182:1303-1311.
9 Xuewei Chen, Junjun Shang, Cailin Lei, Jichen Xu, Shigui Li, Lihuang Zhu. 2008. Genetic and Molecular Analyses of Blast Resistance in a Universal Blast Resistant Variety, Digu. G.-L. Wang, B. Valent (eds.) Advances in Genetics, Genomics and Control of Rice Blast Disease, 149-159.
10 Xuewei Chen, Junjun Shang, Dexi Chen, Cailin Lei, Yan Zou, Wenxue Zhai, Guozhen Liu, Jichen Xu, Zhongzhuan Ling, Gang Cao, Bingtian Ma, Yuping Wang, Xianfeng Zhao, Shigui Li, Lihuang Zhu. 2006, A B-lectin receptor kinase gene conferring rice blast resistance. The Plant Journal, 46 (5), 794–804.
11 Chang-Jin Park, Ying Peng, Xuewei Chen, Christopher Dardick, DeLing Ruan, Rebecca Bart, Patrick E. Canlas, Pamela C. Ronald. 2008, Rice XB15, a Protein Phosphatase 2C, Negatively Regulates Cell Death and XA21-Mediated Innate Immunity. PLoS Biology, 6(9) e231.
12 Chang-Jin Park, Sang-Wook Han, Xuewei Chen, and Pamela C. Ronald. 2010, Elucidation of XA21-mediated innate immunity. Cellular Microbiology, 12(8):1017-25.
13 CHEN De-xi, CHEN Xue-wei, MA Bing-tian, WANG Yu-ping, ZHU Li-huang, LI Shi-gui. 2010, Genetic Transformation of Rice with Pi-d2 Gene Enhances Resistance to Rice Blast Fungus Magnaporthe oryzae. Rice Science, 17(1)
14 Ying Peng, Laura E. Bartley, Xuewei Chen, Christopher Dardick, Mawsheng Chern, Randy Ruan, Patrick E. Canlas, Pamela C. Ronald. 2008, OsWRKY62 is a Negative Regulator of Basal and Xa21-Mediated Defense against Xanthomonas oryzae pv. oryzae in Rice. Molecular Plant. 1: 446-458.
15 Lei Li, Xiangfeng Wang, Rajkumar Sasidharan, Viktor Stolc, Wei Deng, Hang He,Jan Korbel, Xuewei Chen, Waraporn Tongprasit, Pamela Ronald, Runsheng Chen, Mark Gerstein, Xing Wang Deng. 2007, Global Identification and Characterization of Transcriptionally Active Regions in the Rice Genome. PLoS ONE, 2(3): e294.
16 Young-Su Seo, Mawsheng Chern, Laura E. Bartley, Muho Han, Ki-Hong Jung,Insuk Lee, Harkamal Walia, Xia Xu, Peijian Cao, Wei Bai, Rajeshwari Ramanan,Fawn Amonpant, Loganathan Arul, Patrick E. Canlas, Randy Ruan, Chang-Jin Park,Xuewei Chen, Sohyun Hwang, Jong-Seong Jeon, and Pamela C. Ronald. 2011, Towards Establishment of a Rice Stress Response Interactome. PLoS Genet, 7(4): e1002020.
17 X.W. Chen, S.G. Li, W.X. Zhai, J.C. Xu, Z.Z. Ling, W.M. Wang, X.B. Li, Y.P. Wang, G. Cao, J.J. Shang, Y.Q. Ma, K.D. Zhou, L.H. Zhu. 2004, Identification of Two Blast Resistance Genes in Rice Digu. Jounal of Phytopathology 152:77–85
18 Zheng X, Chen X, Zhang X, Lin Z, Shang J, Xu J, Zhai W, Zhu L.2004, Isolation and identification of a gene in response to rice blast disease in rice. Plant Molecular Biology, 54: 99–109
19 Wenxue Zhai, Caiyan Chen, Xuefeng Zhu, Xuewei Chen, Dechun Zhang, Xiaobing Li, Lihuang Zhu. 2004, Analysis of T-DNA- Xa21 loci and bacterial blight resistance effects of the transgene Xa21 intransgenic rice.Theoretic Applied Genetics.109: 534–542
20 ZHONG Yiming, JIANG Guanghuai, CHEN Xuewei, XIA Zhihui, LI XiaobingZHU Lihuang, ZHAI Wenxue Identification and gene prediction of a 24 kb region containing xa5, a recessive bacterial blight resistance gene in rice (Oryza sativa L.) 2003, Chinese Science Bulletin. 48(1), 2725-2729.
21 Yu, J., …, Chen,X., …., and Yang, H. 2002, A draft sequence of the rice genome (Oryza sativa L. ssp. indica).Science. 296, 79-92.
22 CHEN Xuewei, Li Shigui, WANG Wenming, Li Hanyun, ZHOU Kaida, ZHU Lihuang. 2001, Molecular tagging of a genic male-sterile gene MS-P in rice. Chinese Science Bulletin. 46(1),66-69. (In English).
23 YU Jun, HU Songnian, -,CHEN Xuewei,-,YANG Huanming. 2001, A draft sequence of the rice (Oryza sativa ssp. indica) genome. Chinese Science Bulletin. 46:1937-1942.
24 W. Wang, W. Zhai, M. Luo, G. Jiang, X. Chen, X. Li, R. A. Wing, L. Zhu. 2001, Chromosome landing at the bacterial blight resistance gene Xa4 locus using a deep coverage rice BAC library., Molecular Genetics and Genomics. 265,118-125.
25 W.M. Wang, W.X. Zhai, G.H. Jiang, X.W. Chen, X.B. Li, L. H. Zhu. 2000, Construction of a BAC contig containing Xa4 locus on Chromosome 11., Rice Genetics Newsletter 17,74-76.
26 Wang Wenmin, ZHOU Yongli, JIANG Guanhuai, MA Bojun, CHEN Xuewei, ZHANG Qi, ZHU Lihuang, ZHAI Wenxue. Fine mapping of the rice bacterial blight resistance gene Xa-4 and its co-segregation marker. 2000, Chinese Science Bulletin. 45(19),1779-1782. (SCI: IF:0.68)
27 W.M. Wang, W.X. Zhai, G.H. Jiang, X.W. Chen, X.B. Li, L. H. Zhu. Construction of a BAC contig containing Xa4 locus on Chromosome 11. 2000, Rice Genetics Newsletter 17,74-76.
28 Xuewei Chen, Li Shigui, Wenming Wang, Hanyun Li, Kaida Zhou, Lihuang Zhu. Molecular mapping of a genic male-sterile gene in rice. 2000, Chinese Science Bulletin. 45(15), 1644-1648. (In Chinese).
29 陳德西,陳學偉,雷財林,馬炳田,王玉平,李仕貴. 2010, 轉Pi-d2基因水稻對稻瘟病的抗性分析,中國水稻科學, 24(1): 31-35.
30 樊穎倫,陳學偉,王春連,朱立煌,章琦,趙開軍. 2006,水稻抗白葉枯病基因Xa23的RFLP標記定位及其STS標記的轉化. 作物學報, 32(06):931-935.
31 陳學偉, 李仕貴, 馬玉清, 黎漢雲, 周開達, 朱立煌. 2004, 水稻抗稻瘟病基因Pi-d(t)1、Pi-b、Pi-ta2的聚合及分子標記選擇.生物工程學報.20 (5):708-714.
32 朱雪峰, 陳學偉, 李曉兵, 錢前, 黃大年, 朱立煌, 翟文學. 轉Xa21基因水稻中T-DNA整合的遺傳定位. 2002, 遺傳學報, 29(10),880-886.
32 王文明, 周永力, 江光懷, 馬伯軍, 陳學偉, 章琦, 朱立煌, 翟文學. 2000, 水稻抗白葉枯病基因Xa-4的精細定位及其共分離分子標記,科學通報,45(19),1779-1782.
科研項目
2018年8月3日,國家自然科學基金委員會公布了2018年度國家傑出青年科學基金建議資助項目申請人名單,陳學偉位列其中。
所獲榮譽
2019年9月20日,獲得2019年科學探索獎。