鄧盛元(南京理工大學環境與生物工程學院副教授)

鄧盛元，出生於1984年10月， 南京理工大學環境與生物工程學院副教授、博士生導師。

基本介紹

• 中文名：鄧盛元
• 國籍：中國
• 出生日期：1984年10月
• 畢業院校：南京大學
• 職業：教師
• 學術代表作：化學與社會 (校級核心公選課)
• 職稱：南京理工大學環境與生物工程學院副教授

研究領域

體外診斷(IVD)、即時檢測(POCT)相關套用場景的分析方法、檢驗技術與終端設備的研發。

教育背景

2003年09月~2007年06月：南京大學，基礎學科理科強化部(匡亞明學院)，本科

2007年09月~2013年01月：南京大學，化學化工學院(生命分析化學國家重點實驗室)，博士(導師：鞠熀先)

2013年01月~2015年04月：南京理工大學，環境與生物工程學院，講師

2014年04月~2014年05月：加拿大多倫多大學，生物分子科學系，訪問學者(合作導師：Shana Kelly)

2015年05月~至今：南京理工大學，環境與生物工程學院，副教授

2016年04月~2018年10月：賓夕法尼亞州立大學，化學與分子生物學系，博士後(合作導師：Paul Cremer)

主講課程

生物納米材料、Biosensors、Biochemistry I、化學與社會、Biocatalysis & Biotransformation

承擔項目

主持課題

01國家自然科學基金面上項目《基於卟啉ECL的多腫瘤標誌物成像新方法研究》(21775072)

02江蘇省基礎研究計畫優秀青年基金項目《基於卟啉ECL的多組分生物分子成像新方法研究》(BK20170093)

03中國博士後科學基金第62批面上資助《卟啉的電致化學發光特性及其分子成像套用研究》(172750)

04企業委託開發《硒糖標誌物的POCT快檢法及在人尿測試中的套用研究》(1191021150)、《硒蛋白P免疫分析法的建立及在人血檢測中的套用研究》

05南京理工大學自主科研專項計畫“新型冠狀病毒肺炎”應急專項《基於側流金層析比色的POCT快檢系統的研製及其在2019-nCoV疑似感染診斷中的套用研究》(30920010015)

06南京理工大學自主科研“傑青/優青”培育專項《基於生物正交化學的循環腫瘤細胞膜糖基定址定量及其藥物介導下的信號轉導研究》

07國家自然科學基金青年基金《基於卟啉仿生納米探針的電致化學發光核酸感測器的研究》(21305067)

08江蘇省自然科學基金青年基金《卟啉@類石墨烯仿生分子探針的設計及電致發光核酸分析套用研究》(BK20130754)

09教育部高等學校博士學科點專項科研基金《新型卟啉基仿生納米探針的設計及其固態電致化學發光核酸感測套用研究》(0133219120019)

10國家留學基金委員會“未來科學家”博士後留學計畫資助項目《循環腫瘤DNA感測技術》(201506840137)

11中央高校基礎研究計畫專項基金《基於納米靜電紡絲的海洋放射性核素綜合利用技術》(30920130112012)

12南京大學生命分析化學國家重點實驗室開放研究基金項目《非貴金屬仿生催化在電致發光生物感測中的套用研究》(SKLACLS1302)

參與課題

01國家自然科學基金面上項目《基於肽核酸入侵的微電極陣列高靈敏雙鏈DNA直接測定研究》(21575066)

02國家自然科學基金青年基金《基於核酸分子門控染料釋放的多色螢光信號同時獲取感測器陣列用於腫瘤標誌物檢測》(21505073)

03國家自然科學基金面上項目《卟啉−半導體納米複合物的組裝與光電生物感測》(21075060)

04國家自然科學基金主任基金《叉指微電極器件上的核酸分子超靈敏電檢測研究》(21345002)

05國家自然科學基金面上項目《面向腫瘤預警與早期診斷的生物標誌物高靈敏檢測新方法研究》(21135002)

06中央高校基礎研究計畫專項基金《生物感測技術在海洋監測中的套用》(30920140112009)

發表論文

通訊或第一作者：

01Terminal−Conjugated Non−Aggregated Constraints of Gold Nanoparticles on Lateral Flow Strips for Mobile Phone Readouts of Enrofloxacin, Biosensors and Bioelectronics2020, 160, 112218

02Porphyrin Trio−Pendant Fullerene Guest as an In Situ Universal Probe of High ECL Efficiency for Sensitive miRNA Detection, Biosensors and Bioelectronics2020, 150, 111963

03In Situ Terminus−Regulated DNA Hydrogelation for Ultrasensitive On−Chip MicroRNA assay, Biosensors and Bioelectronics2019, 137, 263

04Enhanced Electrochemiluminescent Brightness and Stability of Porphyrins by Supramolecular Pinning and Pinching for Sensitive Zinc Detection, Analytical and Bioanalytical Chemistry2019, 411, 4797 (Topical Collection of Young Principal Investigator in (Bio-)Analytical Chemistry)

05In Situ Formed Copper Nanoparticles Templated by TdT−Mediated DNA for Enhanced SPR Sensor−Based DNA Assay, Biosensors and Bioelectronics2017, 97, 1

06Polymerization Amplified SPR−DNA Assay on Noncovalently Functionalized Graphene, Biosensors and Bioelectronics2017, 89, 319

07Electro−Photodynamic Visualization of Singlet Oxygen Induced by Zinc Porphyrin Modified Microchip in Aqueous Media, ACS Applied Materials and Interfaces2016, 8, 34833

08Dumbbell−Shaped Carbon Quantum Dots/AuNCs Nanohybrid as an Efficient Ratiometric Fluorescent Probe for Sensing of Cadmium(II) Ions and L−Ascorbic Acid, Carbon2016, 96, 1034

09Cathodic Electrochemiluminescence of Singlet Oxygen Induced by the Electroactive Zinc Porphyrin in Aqueous Media, Electrochimica Acta2016, 190, 64

10Specific Electrochemiluminescence of Aptamer−Functionalized Quantum Dots with Lysozyme and Hemin as Co−Triggers, Chinese Journal of Chemistry2016, 34, 331

11Detection of Zinc Finger Protein (EGR1) Based on Electrogenerated Chemiluminescence from Singlet Oxygen Produced in a Nanoclay−Supported Porphyrin Environment, Analytical Chemistry2015, 87, 9155

12Carbon Nitride Nanosheet−Supported Porphyrin: A New Biomimetic Catalyst for Highly Efficient Bioanalysis, ACS Applied Materials and Interfaces2015, 7, 543

13Mass Effect of Redox Reactions: A Novel Mode for Surface Plasmon Resonance−Based Bioanalysis, Biosensors and Bioelectronics2015, 74, 183

14Pyrocatechol Violet−Assisted In Situ Growth of Copper Nanoparticles on Carbon Nanotube: the Synergic Effect for Non−Enzymatic Electro−Chemical Sensing of Hydrogen Peroxide, Electrochimica Acta2015, 155, 78

15Unusual Fe(CN)₆ Capture Induced by Synergic Effect of Electropolymeric Cationic Surfactant and Graphene: Characterization and Biosensing Application, ACS Applied Materials and Interfaces2014, 6, 21161

16Chronopotentiometric Synthesis of Quantum Dots with Efficient Surface−Derived Near−Infrared Electrochemi- luminescence for Ultrasensitive Microchip−Based Ion−Selective Sensing, RSC Advances2014, 4, 29239

17Electrochemiluminescent Quenching of Quantum Dots for Ultrasensitive Immunoassay through Oxygen Reduction Catalyzed by Nitrogen−Doped Graphene−Supported Hemin, Analytical Chemistry2013, 85, 5390

18Label−Free Electrochemiluminescent Detection of DNA by Hybridization with Molecular Beacon to Form Hemin/G−Quadruplex Architecture for Signal Inhibition, Nanoscale2013, 5, 5435

19A Ferrocenyl−Terminated Dendrimer as Efficient Quencher via Electron and Energy Transfer for Cathodic Electrochemiluminscent Immunoassay, Chemical Communications2013, 49, 2106 (Inside Front Cover)

20Synthesis and Low−Potential Electrogenerated Chemiluminescence of Surface Passivated Phenol Formaldehyde Resin@CdS Quantum Dots, Journal of Materials Chemistry C2013, 1, 299

21Electrogenerated Chemiluminescence of Nanomaterials for Bioanalysis, Analyst2013, 138, 43 (ESI, "Top Ten Most Accessed Articles in 2013")

22Electrocatalytic Reduction of Coreactant by Highly Loaded Dendrimer−Encapsulated Palladium Nanoparticles for Sensitive Electrochemiluminescent Immunoassay, Chemical Communications2012, 48, 9159

23Signal Amplification by Adsorption−Induced Catalytic Reduction of Dissolved Oxygen on Nitrogen−Doped Carbon Nanotubes for Electrochemiluminescent Immunoassay, Chemical Communications2011, 47, 12107

24Amplified Electrochemiluminescence of Quantum Dots by Electrochemically Reduced Graphene Oxide for Nanobiosensing of Acetylcholine, Biosensors and Bioelectronics2011, 26, 4552

25A Glucose Biosensor Based on Direct Electrochemistry of Glucose Oxidase Immobilized on Nitrogen-Doped Carbon Nanotubes, Biosensors and Bioelectronics2009, 25, 373 (ESI, "Most Cited Biosensors and Bioelectronics Articles")

其他：

01Aptamer−Initiated On−Particle Template−Independent Enzymatic Polymerization (Aptamer− OTEP) for Electrochemical Analysis of Tumor Biomarkers, Biosensors and Bioelectronics2016, 86, 536

02Preparation of Amidoximated Coaxial Electrospun Nanofibers for Uranyl Uptake and Their Electrochemical Properties, Separation and Purification Technology2016, 171, 44

03Ultrasensitive Electrochemical Aptasensor Based on Surface−Initiated Enzymatic Polymerization, Chinese Journal of Chemistry2016, 34, 337

04Magnetic Zirconium Hexacyanoferrate(II) Nanoparticle as Tracing Tag for Electrochemical DNA Assay, Analytical Chemistry2015, 87, 9093

05Aptamer−Wrapped Gold Nanoparticles for the Colorimetric Detection of Omethoate, Science China Chemistry2015, 59, 237 (Annual Excellent Paper)

06Influence of 4−Tert−Butylpyridine/Guanidinium Thiocyanate Co−Additives on Band Edge Shift and Recombination of Dye−Sensitized Solar Cells: Experimental and Theoretical Aspects, Electrochimica Acta2015, 185, 69

07Ferricyanide Confined into the Integrative System of Pyrrolic Surfactant and SWCNTs: The Enhanced Electrochemical Sensing of Paracetamol, Electrochimica Acta2015, 186, 16

08Sequential Electro−Deposition of Highly Stable Cu−Fe Prussian Blue Coordination Polymers at Indium Tin Oxide Electrode: Characterization and the Enhanced Sensing Application, Journal of the Electrochemical Society2015, 162, H918

09Platinum Nanodendrites Functionalized Graphene Nanosheets as Nonenzymatic Label for Electrochemical Immunosensing, Journal of Materials Chemistry B2014, 1, 5347

10Electrochemical Studies on the Interfacial Behaviors for the Eco−Friendly Magnetic Nanoparticles Based on Gamma−Fe₂O₃, Electrochimica Acta2014, 138, 486

11Ionic Iridium Complex Coordinated with Tetrathiafulvalene−Fused Phenanthroline Ligand: Synthesis, Photophysical, Electrochemical and Electrochemiluminescence Properties, Journal of Organometallic Chemistry2014, 750, 7

12Bioinspired Polydopamine as the Scaffold for the Active AuNPs Anchoring and the Chemical Simultaneously Reduced Graphene Oxide: Characterization and the Enhanced Biosensing Application, Biosensors and Bioelectronics2013, 49, 466

13Graphene−Supported Ferric Porphyrin as Peroxidase Mimic for Electrochemical DNA Biosensing, Chemical Communications2013, 49, 916 (ESI)

14Chemiluminescence Excited Photoelectrochemistry Using Graphene−Quantum Dots Nanocomposite for Biosensing, Chemical Communications2012, 48, 6535

15Ultrasensitive Immunoassay of Protein Biomarker Based on Electrochemiluminescent Quenching of Quantum Dots by Hemin Bio−Bar−Coded Nanoparticle Tags, Analytical Chemistry2011, 83, 5214

16Electrochemical Synthesis of Reduced Graphene Sheet−AuPd Alloy Nanoparticle Composites for Enzymatic Biosensing, Biosensors and Bioelectronics2011, 29, 159

17Disposable Electrochemiluminescent Biosensor Using Bidentate−Chelated CdTe Quantum Dots as Emitter for Sensitive Detection of Glucose, Analyst2011, 137, 140

18Carbon Nanospheres Enhanced Electrochemiluminescence of CdS Quantum Dots for Biosensing of Hypoxanthine, Talanta2011, 85, 2154

19Pt−Dispersed Flower−Like Carbon Nanosheet Aggregation for Low−Overpotential Electrochemical, Biosensing, Biosensors and Bioelectronics2010, 26, 432

20Electrochemiluminescence of CdSe Quantum Dots Composited with Nitrogen-Doped Carbon Nanotubes, Electroanalysis2009, 21, 2495

21Ultra−Large Scale Molecular Dynamics Simulation for Nano−Engineering, Chemical Research in Chinese Universities2008, 24, 367

22Where, and How, Does a Nanowire Break?Nano Letter2007, 7, 1208

授權專利

[1](專利號：201710051776.X)《(3,4,5-三(十二烷氧基)苯甲基)三苯基四氟硼酸鏻及其在電致化學發光中的套用》(授權日：2019年06月25日)

[2](專利號：2017104130370)《一種基於ZnTCPP@MOF的電化學免疫檢測微囊藻毒素的方法》(授權日：2018年12月03日)

[3](專利號：201510478459.7)《一種ZnTCPP/TOAB發光電極、製備方法及其在發光成像平台中的套用》(授權日：2018年06月12日)

[4](專利號：201510501355.3)《基於間四苯基卟啉鋅的電致化學發光體、製備方法及其套用》(授權日：2017年11月14日)

[5](專利號：201510107736.3)《基於ZnPPIX電致化學發光的離子選擇性電極及其套用》(授權日：2017年04月19日)

[6](專利號：201410241361.5)《一種過氧化物模擬酶、製備及其套用》(授權日：2016年04月20日)

會議報告

01Ligand Binding Causes Electro−Reduced Porphyrin Receptors to Chemotax, 5 International Symposium on Electrochemistry: "Electrochemistry at Nanostructured Interfaces", Cape Town, South Africa, 2019 (Oral)

02Enhanced Electrochemiluminescent Brightness and Stability of Porphyrins by Supramolecular Pinning and Pinching for Sensitive Zinc Detection, 70 Annual Meeting of the International Society of Electrochemistry, Durban, South Africa, 2019

03Glucose Fuel Cell−Stimulated Robotics of Janus Structure, International Symposium on "Energy Storage and Industry 4.0: Challenges and Prospects", Sun City, South Africa, 2019

04Molecular Binding Induced Chemotaxis, Annual Motors' Meeting of Materials Research Science and Engineering Centers (MRSEC), University Park, U.S., 2017 (Oral)

05Electro−Photodynamic Visualization of Singlet Oxygen Induced by Zinc Porphyrin Modified Microchip in Aqueous Media, 253 National Meeting of the American Chemical Society (ACS) on Advanced Materials, Technologies, Systems, and Processes, Philadelphia, U.S., 2017

06Label−Free Biomimetic Electrocatalysis−Induced Precipitation for Ultrasensitive Bioanalysis, 65 Annual Meeting of the International Society of Electrochemistry,Lausanne, Switzerland, 2014

07Cathodic Electrochemiluminescence of Porphyrin for Solid−State Ion−Selective Sensing,1 International Meeting on Electrogenerated Chemiluminescence (ECL' 2014), Bertinoro, Italy, 2014

08Rational Design of Bioinspired Oxygen Reductase for Electrochemiluminescent Determination of Sequence−Encoding Hemagglutinin of Avian Influenza Virus, 14 Topical Meeting of the International Society of Electrochemistry − Electrochemistry for Life Science and Bioanalysis, Nanjing, China, 2013

09Surface−Derived Near−Infrared Electrochemiluminescence from Electrogenerated Antidote− Stabilized Quantum Dots for Microsensing of Bordeaux Mixture Residue, 14 International Symposium on Electroanalytical Chemistry(14 ISEAC), Changchun, China, 2013

10G−Quadruplex Promoted Electrogenerated Phosphorescence of Zinc(II) Protoporphyrin IX as DNAzyme for Molecular Scale Signal Transduction, 15 Topical Meeting of the International Society of Electrochemistry − Interfacial Electrochemistry at Atomic, Molecular and Nanoscale Domains, Niagara, Canada, 2013

11Electrochemical Synthesis of Reduced Graphene Sheet−AuPd Alloy Nanoparticle Composites for Enzymatic Biosensing, 220 The Electrochemical Society (ECS) Annual Meeting and Electrochemical Energy Summit, Boston, U.S., 2011

獎勵榮譽

(1)南京理工大學校級一類獎勵“2015~2016年度青年教師進步獎”，2016年09月；

(2)江蘇高校“青藍工程”優秀青年骨幹教師培養對象，2016年04月；

(3)教育部高等教育司“中國大學視頻公開課”精品視頻公開課《神奇的化學元素》，2015年04月，排名3；

(4)高等教育學會“大學素質教育精品通選課”A類《化學與社會》，2015年04月，排名2；

(5)南京市“第十一屆自然科學學術論文獎”《氮化碳納米薄片支撐的卟啉一種新穎的仿生催化劑用於高效的生物分析》，2015年04月；

(6)南京理工大學“卓越計畫”之“紫金之星”第一層次培養對象《面向腫瘤早期診斷的新型分子診斷和細胞成像技術研究》，2015年01月；

(7)教育部“高等學校科學研究優秀成果獎自然科學獎”一等獎《生物分子與細胞高效檢測新原理與分析新方法研究》，2014年03月，排名8。