基本介紹
- 中文名：鄒望遠
- 學位/學歷：博士
- 職業：教師
- 專業方向：麻醉學
- 任職院校：中南大學
個人經歷,研究方向,學術成果,榮譽獎項,
個人經歷
教育經歷
2008.9-2011.6中南大學| 麻醉學 博士學位| 博士研究生畢業 湘雅醫院
2001.9-2004.6中南大學| 麻醉學 碩士學位| 碩士研究生畢業 湘雅醫院
1996.9-2001.6 中南大學| 麻醉學 學士學位| 大學本科畢業 湘雅醫學院
工作經歷
2014.9-至今麻醉科| 湘雅醫院
2013.12-2014.12神經科學系| 約翰·霍普金斯大學醫學院 | 國家公派留學訪問學者
2013.9-至今麻醉科| 湘雅醫院
2007.9-2013.8麻醉科| 湘雅醫院
2004.7-2007.8麻醉科| 湘雅醫院
社會兼職
社會兼職內容：開始時間：2019-10-01 結束時間： 2022-09-01
中華醫學會麻醉學分會青年委員
中國醫師協會麻醉醫師分會青年委員
國家科技專家庫專家
社會兼職內容：開始時間：2015-09-01 結束時間： 2019-09-01
中國研究型醫院協會麻醉學分會委員
湖南省麻醉學分會青年委員
美國神經科學協會會員
中南大學青年科協成員
研究方向
1、慢性疼痛及阿片耐受的機制研究
2、圍術期過敏反應及類過敏反應
3、圍術期氣道管理及其轉化研究
學術成果
論文成果
1. Zhang Z, Deng M, Huang J, et al.Microglial Annexin A3 downregulation alleviates bone cancer-induced pain viainhibiting the Hif-1α/VEGF signaling pathway [published online ahead of print,2020 Jun 18]. Pain. doi:10.1097/j.pain.0000000000001962. (SCI, IF=6.024, JCR Q1).
2. Wang J, Xu W, Kong Y,Huang J, Ding Z, Deng M, Guo Q, Zou W*.SNAP-25Contributes to Neuropathic Pain by Regulationof VGLuT2 Expression in Rats.Neuroscience. 2019 Nov 6.
3. Weng Y, Wu J, Li L,Shao J, Li Z, Deng M, Zou W*.Circular RNA expression profilein the spinal cord of morphine tolerated rats and screen of putative key circRNAs. Mol Brain. 2019 Sep 18;12(1):79.
4. Huang J, Wang J, GuoQ, ZouW*. Emerging roles of microRNAs in morphine
tolerance. J Pain Res.2019;12:1139-1147.
5. Liang X, Huang J, Xing M, He L, Zhu X,Weng Y, Guo Q, Zou W*. Risk factors and outcomes of urosepsis inpatients with calculous pyonephrosis receiving surgical intervention: asingle-center retrospective study. BMC Anesthesiol.2019;19(1):61.
6. Huang J, Liang X, Wang J, Kong Y, Zhang Z,Ding Z, Song Z, Guo Q, Zou W*.
miR-873a-5p Targets A20 to Facilitate MorphineTolerance in Mice.Front Neurosci.2019;13:347.
7. Huang J, Zhang C, Wang J, Guo Q, Zou W*.Oral Lactobacillus reuteri LR06 or
Bifidobacterium BL5b supplement do not produceanalgesic effects on neuropathic and inflammatory pain in rats. BrainBehav. 2019;9(4):e01260.
8. Shao J, Wang J, HuangJ, Liu C, Pan Y, Guo Q, Zou W*. Identification of lncRNA expression profiles and ceRNAanalysis in the spinal cord of morphine-tolerant rats. Mol Brain.2018;11(1):21.
9. Gui Y, Li A, Zhang J, Li G, Ruan X, Guo Q,Zou W*.α-Asarone Alleviated Chronic Constriction Injury-InducedNeuropathic Pain Through Inhibition of Spinal Endoplasmic Reticulum Stress inan Liver X Receptor-Dependent Manner. Anesth Analg. 2018;127(3):775-783. (SCI, JCR Q1).
10. Zou W*, Xu W, Song Z, Zhong T, Weng Y, Huang C, Li M, Zhang C,Zhan X, Guo Q*. Proteomic Identification of an Upregulated Isoform of AnnexinA3 in the Spinal Cords of Rats in a Neuropathic Pain Model. FrontNeurosci. 2017 5;11:484. (SCI, IF=3.566).
11. Zou W*, Shao J, LiangX, Li L, He Z, Guo Q. A randomized comparison of the
prone ventilation endotracheal tube versus thetraditional endotracheal tube in adult patients undergoing prone positionsurgery. Sci Rep. 2017;7(1):1769. (SCI,IF=5.228, JCR Q1).
12. Wang J, Xu W, Shao J, He Z, Ding Z, HuangJ, Guo Q, Zou W*. miR-219-5p targets CaMKIIγ to attenuate morphinetolerance in rats. Oncotarget. 2017;8(17):28203-28214.
13. Wang J, Xu W, Zhong T, Song Z, Zou Y, DingZ, Guo Q, Dong X, Zou W*. miR-365 targets β-arrestin 2 to reversemorphine tolerance in rats. Sci Rep. 2016;6:38285. (SCI, IF=5.228, JCR Q1).
14. Weng HJ, Patel KN, Jeske NA, Bierbower SM, Zou W, Tiwari V, Zheng Q, Tang Z, Mo GC, Wang Y, Geng Y, Zhang J, Guan Y, Akopian AN, Dong X. Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain. Neuron. 2015;85(4):833-846. (SCI, IF=15.982).
15. Zhong T, Guo Q, Zou W, Zhu X, Song Z, Sun B, He X, Yang Y. Neonatal isoflurane exposure induces neurocognitive impairment and abnormal hippocampal histone acetylation in mice. PLoS One. 2015;10(4):e0125815.
16. Zhong T, Qing QJ, Yang Y, Zou WY, Ye Z, Yan JQ, Guo QL. Repression of contexual fear memory induced by isoflurane is accompanied by reduction in histone acetylation and rescued by sodium butyrate. Br J Anaesth. 2014;113(4):634-643.
17. He Z, Guo Q, Xiao M, He C, Zou W*.. Intrathecal Lentivirus-mediated Transfer of Interleukin-10 Attenuates Chronic Constriction Injury-induced Neuropathic Pain through Modulation of Spinal High-mobility Group Box 1 in Rats. Pain Physician.2013 ,16(5):E615-625. Intrathecal Lentivirus-mediated Transfer of Interleukin-10 Attenuates Chronic Constriction Injury-induced Neuropathic Pain through Modulation of Spinal High-mobility Group Box 1 in Rats.pdf
18. Zou W, Song Z, Guo Q, Liu C, Zhang Z, Zhang Y. Intrathecal Lentiviral-Mediated RNA Interference Targeting PKCγ Attenuates Chronic Constriction Injury-Induced Neuropathic Pain in Rats. Hum Gene Ther. 2011; 22(4):465-475.
19. Zou W, Zhan X, Li M, Song Z, Liu C, Peng F, Guo Q. Identification of differentially expressed proteins in the spinal cord of neuropathic pain models with PKCgamma silence by proteomic analysis. Brain Res.2012;1440:34-46.
20. Song Z, Guo Q, Zhang J, Li M, Liu C, Zou W*. Proteomic Analysis of PKCγ-Related Proteins in the Spinal Cord of Morphine-Tolerant Rats. PLoS One.2012;7(7):e42068.
21. Song Z, Zou W*, Liu C, Guo Q. Gene knockdown with lentiviral vector-mediated intrathecal RNA interference of protein kinase C gamma reverses chronic morphine tolerance in rats. J Gene Med. 2010;12(11):873-880.
22. Zou W, Zhang W, Li X, Guo Q. A randomized crossover comparison of the prone ventilation endotracheal tube versus the traditional endotracheal tube in pediatric patients undergoing prone position surgery. Paediatr Anaesth. 2013;23(1):98-100. A randomized crossover comparison of the prone ventilation endotracheal tube versus the traditional endotracheal tube in pediatric patients undergoing prone position surgery.pdf
23. Zou W, Huang C, Yang Y, Pan Y, Yan J, Guo Q. Microinjection of HSV-1 amplicon vector-mediated human proenkephalin into the periaqueductal grey attenuates neuropathic pain in rats. Int J Neurosci. 2012; 122(4):189-194.
24. Zou W, Guo Q, Chen C, Yang Y, Wang E. Intrathecal herpes simplex virus type 1 amplicon vector-mediated human proenkephalin reduces chronic constriction injury-induced neuropathic pain in rats. Mol Med Report. 2011;4(3):529-533.
25. Zou W, Hu H, Guo Q, Liu Y, Ren F, Yan J. A case of unusual difficult airway because of an intracranial foreign body of bamboo chopstick. Paediatr Anaesth.2009;19(9):921-923.
26. Zou W, Guo Q, Wang E, Cai J, Cheng Z. Intrathecal morphine suppresses immune function in rats with inflammatory-induced pain. J Int Med Res, 2007;35(5):626-636.
27. Liu C, Guo QL, Huang CS, Zou WY, Song ZB. Suppressing SNAP-25 and reversing glial glutamate transporters relieves neuropathic pain in rats by ameliorating imbalanced neurotransmission. Chin Med J (Engl). 2013 , 126(21):4100-4104.
28. Huang C, Zou W, Lee K, Wang E, Zhu X, Guo Q. Different symptoms of neuropathic pain can be induced by different degrees of compressive force on the C7 dorsal root of rats. Spine J. 2012;12(12):1154-1160.
29. Kuang X, Huang Y, Gu HF, Zu XY, Zou WY, Song ZB, Guo QL. Effects of intrathecal epigallocatechin gallate, an inhibitor of Toll-like receptor 4, on chronic neuropathic pain in rats. Eur J Pharmacol. 2012;676(1-3):51-56.
30. Zhu XY, Huang CS, Li Q, Chang RM, Song ZB, Zou WY, Guo QL. p300 exerts an epigenetic role in chronic neuropathic pain through its acetyltransferase activity in rats following chronic constriction injury (CCI). Mol Pain. 2012； 23;8(1):84.
31. Wang Y, Liu C, Guo QL, Yan JQ, Zhu XY, Huang CS, Zou WY. Intrathecal 5-azacytidine inhibits global DNA methylation and methyl- CpG-binding protein 2 expression and alleviates neuropathic pain in rats following chronic constriction injury. Brain Res. 2011; 1418:64-69.
32. Pan YD, Guo QL, Wang E, Ye Z, He ZH, Zou WY, Cheng ZG, Wang YJ. Intrathecal infusion of pyrrolidine dithiocarbamate for the prevention and reversal ofneuropathic pain in rats using a sciatic chronic constriction injury model. Reg Anesth Pain Med. 2010;35(3):231-237.
科研項目
[2]國家自然科學基金面上項目：microRNA-219-5p和microRNA-365調控慢性嗎啡耐受的分子機制研究
[3]國家自然科學基金青年基金項目：PKCγ基因調控慢性嗎啡耐受的比較蛋白質組學研究
[4]中南大學湘雅醫院“優秀青年科研人才培育計畫”：脊髓背角miRNA-219-5p和miRNA-365參與慢性嗎啡耐受的機制研究
[5]中南大學湘雅醫院2013年“臨床科研基金”培養項目：俯臥位通氣氣管導管的臨床套用研究
[6]國家自然科學基金面上項目：PKCγ基因調控神經病理性疼痛的蛋白質組學研究
[7]國家自然科學基金青年基金項目：P300/CBP介導調控神經病理性疼痛的表觀遺傳學研究
[8]國家自然科學基金青年基金項目：GDNF通過激活Ret介導信號通路參與骨癌痛-嗎啡耐受的機制研究
專利成果
[1]一種內源性的非編碼小 RNA miR-873的套用
[2]一種針對PKCγ基因RNA干擾的重組慢病毒載體及其構建和套用
[3]俯臥位通氣氣管導管
[4]一種針對PKCγ基因RNA干擾的重組慢病毒載體及其構建和套用
著作成果
[1]分子麻醉學
榮譽獎項
[1]湖南省醫學科技獎二等獎（2013年）
[2]湖南省科技進步獎三等獎（2013年）
[3]湖南省第十四屆自然科學優秀學術論文一等獎（2012年）
[4]湖南省醫學會醫學優秀學術論文獎一等獎（2012年）
[5]中南大學醫療新技術獎（2012年）
[6]湘雅醫院醫療新技術成果獎（2012年）
[7]全國麻醉學年會中青年優秀論文大賽一等獎（2011年）
[8]全國中青年麻醉醫師學科論壇三等獎（2009年）
[9]湖南省第二屆恩華杯中青年麻醉醫師論文大賽一等獎（2009年）
[10]湖南省第十二屆自然科學優秀學術論文二等獎（2008年）
[11]湖南省首屆恩華杯中青年麻醉醫師論文大賽一等獎（2008年）
