遺傳學——從基因到基因組
科學版研究生教學叢書 | ||||
Hartwell，L.H.(美) 著 | ||||
科學出版社 | 2003年6月出版 | |||
定價：78.00 | 語種：英文 | |||
標準書號：7-03-011098-6 | 裝幀：平裝 | |||
版本：第一版 影印版 | 開本：大16開 | |||
責任編輯：蓋宇 | 字數：1866千字 | |||
讀者對象：本科以上文化程度 | 頁數：865 | |||
書類：研究生教育類 | 冊/包：3 | |||
編輯部： 科學生物分社 | ||||
附註： | ||||
本書目錄
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20世紀大家見證了生物學核心領域遺傳學的興起。鑑定單個基因及其功能後，遺傳學研究者逐漸意識到，沒有基因是單獨作用的，各種生命事件是經由基因和蛋白質網路複雜分子的相互作用。
本書試圖集成當代遺傳學知識和方法，內容主要包括經典遺傳學——基因傳遞規律；分子遺傳學——DNA結構及其如何指導蛋白質合成；基因組學——基因分離新技術和有機體完整基因組深入分析；人類遺傳學——基因如何調控健康和疾病狀態；生命形式的統一——來自不同有機體的信息合成為一個整體核心；分子進化——物種如何進化和趨異。
本書適用於高等院校生命科學、醫藥衛生、農林漁牧等專業師生使用，並可供相關專業研究人員閱讀參考。
本書試圖集成當代遺傳學知識和方法，內容主要包括經典遺傳學——基因傳遞規律；分子遺傳學——DNA結構及其如何指導蛋白質合成；基因組學——基因分離新技術和有機體完整基因組深入分析；人類遺傳學——基因如何調控健康和疾病狀態；生命形式的統一——來自不同有機體的信息合成為一個整體核心；分子進化——物種如何進化和趨異。
本書適用於高等院校生命科學、醫藥衛生、農林漁牧等專業師生使用，並可供相關專業研究人員閱讀參考。
目錄
About the Autmor
Preface
PROLOGUE
PART Ⅰ Basic Principles:How Traits Are Transmitted
CHAPTER 1 Mendel\'s Breakthrough:Patterns,Particles,and Principles of Heredity
CHAPTER 2 Extensions to Mendel:Complexities in Relating Genotype to Phenotype
CHAPTER 3 The Chromosome Theory of Inheritance
CHAPTER4 Linkage,Recombination,and the Mapping of Genes on Chromosomes
PART Ⅱ What Genes Are and What They Do
CHAPTER 5 DNA:How the Molecule of Heredity Carries,Replicate,and Recombines
CHAPTER 6 Anatomy and Function of a Gene:Dissection Through Mutation
CHAPTER 7 Gene Expression:The Flow of Genetic Information from DNA via RNA to Protein
PART Ⅲ Using Genetic Engineering to Unravel the Information in Genomes
CHAPTER 8 DNA a High Resolution:Use of DNA Cloning,PCR,and Hybridization as the Tools of Genetic Analysis
CHAPTER 9 The Direct Detection of Genotype
CHAPTER 10 The Mapping and Analysis of Genomes
PART Ⅳ How Genes Travel
CHAPTER 11 The Eukaryotic Chromosome:An Organelle for Packaging and Managing DNA
CHAPTER 12 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes
CHAPTER 13 The Prokaryotic Chromosome:Genetic Analysis in Bacteria
CHAPTER 14 The Chromosomes of Organelles Outside the Nucleus Exhibitis NonMendelian Patterns of Inheritance
PART Ⅴ How Genes Are Regulated
CHAPTER 15 Gene Regulation in Prokaryotes
CHAPTER 16 Gene Regulation in Eukaryotes
CHAPTER 17 Cell-Cycle Regulation and the Genetics of Cancer
PART Ⅵ Gene Regulation and Development:Portraits of Model Eukaryotic Organisms
USING GENETICS TO STUDY DEVELOPMENT
An Introduction to the Genetic Portraits
CHAPTER 18 Saccharomyes cerevisiae:A Genetic Portrait of Yeast
CHAPTER 19 Arabidopsis thalinana:Genetic Portrait of a Model Plant
CHAPTER 20 Caenorhabditis elegans:Genetic Portrait of a Simple Multicellular Animal
CHAPTER 21 Drosophila melanogaster:Genetic Portrait of the Fruit Fly
CHAPTER 22 Mus musculus:A Genetic Portrait of the House Mouse
PART Ⅶ How Genes Change
CHAPTER 23 The Genetic Analysis of Populations and How They Evolve
CHAPTER 24 Evolution at the Molecular Level
EPILOGUE Human Genetics and the Future of
APPENDIX A Guidelines for Gene Nomenclature
APPENDIX B Brief Answers Section
GLOSSARY
CREDITS
INDEX
Preface
PROLOGUE
PART Ⅰ Basic Principles:How Traits Are Transmitted
CHAPTER 1 Mendel\'s Breakthrough:Patterns,Particles,and Principles of Heredity
CHAPTER 2 Extensions to Mendel:Complexities in Relating Genotype to Phenotype
CHAPTER 3 The Chromosome Theory of Inheritance
CHAPTER4 Linkage,Recombination,and the Mapping of Genes on Chromosomes
PART Ⅱ What Genes Are and What They Do
CHAPTER 5 DNA:How the Molecule of Heredity Carries,Replicate,and Recombines
CHAPTER 6 Anatomy and Function of a Gene:Dissection Through Mutation
CHAPTER 7 Gene Expression:The Flow of Genetic Information from DNA via RNA to Protein
PART Ⅲ Using Genetic Engineering to Unravel the Information in Genomes
CHAPTER 8 DNA a High Resolution:Use of DNA Cloning,PCR,and Hybridization as the Tools of Genetic Analysis
CHAPTER 9 The Direct Detection of Genotype
CHAPTER 10 The Mapping and Analysis of Genomes
PART Ⅳ How Genes Travel
CHAPTER 11 The Eukaryotic Chromosome:An Organelle for Packaging and Managing DNA
CHAPTER 12 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes
CHAPTER 13 The Prokaryotic Chromosome:Genetic Analysis in Bacteria
CHAPTER 14 The Chromosomes of Organelles Outside the Nucleus Exhibitis NonMendelian Patterns of Inheritance
PART Ⅴ How Genes Are Regulated
CHAPTER 15 Gene Regulation in Prokaryotes
CHAPTER 16 Gene Regulation in Eukaryotes
CHAPTER 17 Cell-Cycle Regulation and the Genetics of Cancer
PART Ⅵ Gene Regulation and Development:Portraits of Model Eukaryotic Organisms
USING GENETICS TO STUDY DEVELOPMENT
An Introduction to the Genetic Portraits
CHAPTER 18 Saccharomyes cerevisiae:A Genetic Portrait of Yeast
CHAPTER 19 Arabidopsis thalinana:Genetic Portrait of a Model Plant
CHAPTER 20 Caenorhabditis elegans:Genetic Portrait of a Simple Multicellular Animal
CHAPTER 21 Drosophila melanogaster:Genetic Portrait of the Fruit Fly
CHAPTER 22 Mus musculus:A Genetic Portrait of the House Mouse
PART Ⅶ How Genes Change
CHAPTER 23 The Genetic Analysis of Populations and How They Evolve
CHAPTER 24 Evolution at the Molecular Level
EPILOGUE Human Genetics and the Future of
APPENDIX A Guidelines for Gene Nomenclature
APPENDIX B Brief Answers Section
GLOSSARY
CREDITS
INDEX
