趙鐳，男，博士，華南理工大學生物科學與工程學院副教授、碩士生導師。
基本介紹
- 中文名：趙鐳
- 職業：教師
- 畢業院校：清華大學
- 學位/學歷：博士
- 專業方向：化學
- 任職院校：華南理工大學
人物經歷,研究方向,開設課程,科研興趣,代表論文,
人物經歷
2006.09 – 2012.06清華大學化學系博士
2008.08 – 2008.11德國柏林洪堡大學化學系聯合培養博士
2009.06 – 2009.09德國柏林洪堡大學化學系聯合培養博士
2002.09 – 2006.06南京大學化學化工學院本科
2017.12 –至今華南理工大學生物科學與工程學院副教授
2012.09 – 2017.04德國馬普分子生理學研究所馬普學會化學基因組中心博士後研究員
研究方向
開設課程
本科生教學
主講本科《無機化學》
本科生導師制
研究生教學
主講研究生實驗課《生命科學高等儀器原理及套用二》
科研興趣
多肽與蛋白質化學。包括多肽的化學與生物合成、修飾多肽的合成、蛋白質的半合成、蛋白翻譯後修飾、蛋白質標記、蛋白-蛋白相互作用的研究、疾病相關蛋白的功能研究等。
代表論文
Lei Zhao, Christiane Ehrt, Oliver Koch, Yao-Wen Wu*.One-Pot N2C/C2C/N2N Ligation To Trap Weak Protein-Protein Interactions, Angew Chem Int Ed Engl. 2016 Jul 4;55(28):8129-33
Aimin Yang,Lei Zhao, Yao-Wen Wu*, Chemical Synthesis and Biological Function of Lipidated Proteins, Topics in Current Chemistry, 2015; 362: 137-82 (#共同一作) (IF: 4.014)
Yao-Wen Wu*,Lei Zhao, Elucidation of Protein Function by Chemical Modification, Concepts and Case Studies in Chemical Biology, 06/2014: 83-104 (Wiley出版化學生物學教材第四版)
Fu Li, Long Yi,Lei Zhao, Aymelt Itzen, Roger S Goody, Yao-Wen Wu*, The role of the hypervariable C-terminal domain in Rab GTPases membrane targeting, Proceedings of the National Academy of Sciences 02/2014; 111(7): 2572-7 (IF: 9.423)
Stephanie Voss,Lei Zhao, Xi Chen, Frank Gerhard, Yao-Wen Wu*, Generation of an intramolecular three-color fluorescence resonance energy transfer probe by site-specific protein labeling, Journal of Peptide Science 02/2014; 20(2) (IF: 1.951)
Lei Zhao, Zhi-Wen Hu, Pei Tong, Yong-Xiang Chen*, Yu-Fen Zhao and Yan-Mei Li*, Addition of Artificial Salt Bridge by Ile646Lys Mutation in gp41 Coiled-Coil Domain Regulate Six-Helical Bundle Formation, Bioorg Med Chem Lett.2013, 23(9):2727-2732 (IF: 2.486)
Jing-Wen Ma,Lei Zhao, Qian Liu, De-Sheng Zhao, Yong-Xiang Chen, Chong Liu, Yu-Fen Zhao, Yan-Mei Li*, Covalently reactive group-modified peptide that specifically react with Lysine16 in Amyloid β, Chem. Commun., 2012 Sep, 48, 10565-10567 (IF: 6.567)
Lei Zhao, Pei Tong, Yong-Xiang Chen , Zhi-Wen Hu , Kun Wang, Yu-Ning Zhang, De-Sheng Zhao, Li-Feng Cai, Ke-Liang Liu, Yu-Fen Zhao and Yan-Mei Li*, A multi-functional peptide as an HIV-1 entry inhibitor based on self-concentration, recognition, and covalent attachment, Org Biomol Chem.2012 Aug 28;10(32):6512-20 (IF: 3.559)
Chen YX,Zhao L,Huang ZP,Zhao YF,Li YM, Facilesynthesis of cyclopeptide-centered multivalent glycoclusters with 'click chemistry' and molecular recognition study by surface plasmon resonance, Bioorg Med Chem Lett.2009 Jul 15;19(14):3775-8 (IF: 2.486)
Wu WH, Sun X, Yu YP, Hu J,Zhao L, Liu Q, Zhao YF, Li YM, TiO2 nanoparticles promote beta-amyloid fibrillation in vitro, Biochem Biophys Res Commun. 2008 Aug 22;373(2):315-8 (IF: 2.371)
Chen YX, Zhao W,Zhao L, Zhao YF, Li YM, Facile synthesis of a pentasaccharide mimic of a fragment of the capsular polysaccharide of Streptococcus pneumoniae type 15C, Carbohydr Res. 2008 Mar 17;343(4):607-14 (IF: 1.817)
