趙宇嵐

趙宇嵐

趙宇嵐,女,博士,華東師範大學生命科學學院副研究員。

基本介紹

  • 中文名:趙宇嵐
  • 學位/學歷:博士
  • 職業:教師
  • 專業方向:炎症及免疫反應、腫瘤的免疫治療、神經發育相關疾病
  • 就職院校:華東師範大學生命科學學院
研究方向,學術成果,

研究方向

1、炎症及免疫反應:主攻朊蛋白對各種細胞炎症及免疫反應的調節作用,以及最終對相關疾病發生髮展的影響,比如腫瘤、自身免疫性疾病。
2、腫瘤的免疫治療:通過改造特定基因的表達來改善免疫細胞的抗腫瘤作用。
3、神經發育相關疾病:研究某些神經發育相關臨床綜合徵的發病機制。

學術成果

發表論文
1.Tang Z, Ma J, Zhang W, Gong C, He J, Wang Y, Yu G, Yuan C, Wang X, Sun Y, Ma J, Liu F*,Zhao Y*. The Role of Prion Protein Expression in Predicting Gastric Cancer Prognosis. J Cancer.
2.He J, Zhu J, Gong C, Qi J, Xiao H, Jiang B*,Zhao Y*. Label-Free Direct Detection of miRNAs with Poly-Silicon Nanowire Biosensors. PLoS One.
3.Gong C, Wei D, Wang Y, Ma J, Yuan C, Zhang W, Yu G,Zhao Y*. A Meta-Analysis of C-Reactive Protein in Patients With Alzheimer's Disease. Am J Alzheimers Dis Other Demen.
4.He X*, Yin W, Ding Y, Cui SJ, Luan J, Zhao P, Yue X, Yu C, Laing X*,Zhao Y*. Higher Serum Angiotensinogen Is an Indicator of IgA Vasculitis with Nephritis Revealed by Comparative Proteomes Analysis. PLoS One.
5.Yu G, Liu H, Zhou W, Zhu X, Yu C, Wang N, Zhang Y, Ma J,Zhao Y, Xu Y, Liao L, Ji H, Yuan C, Ma J*. In vivo protein targets for increased quinoprotein adduct formation in aged substantia nigra. Exp Neurol.
6.He J, Zhang F, Wu Y, Zhang W, Zhu X, He X, Zhao Y, Zhang W,Zhao Y*. Prognostic role of microRNA-155 in various carcinomas: results from a meta-analysis.Dis Markers.
7.Zhu X, Zhang F, Zhang W, He J,Zhao Y*, Chen X*. Prognostic role of epidermal growth factor receptor in head and neck cancer: a meta-analysis.J Surg Oncol.
8.Zhao D, Zhang F, Zhang W, He J,Zhao Y*, Sun J*. Prognostic role of hormone receptors in ovarian cancer: a systematic review and meta-analysis.Int J Gynecol Cancer.
9.Zhang W, He J, Zhang F, Huang C, Wu Y, Han Y, Zhang W,Zhao Y*.Prognostic role of C-reactive protein and interleukin-6 in dialysis patients: a systematic review and meta-analysis.J Nephrol.
10.He X,Zhao Y, Li Y, Kang S, Ding Y, Luan J, Zhao P, Liu N, Yin W. Serum amyloid A levels associated with gastrointestinal manifestations in Henoch-Schönlein purpura.Inflammation.
11.Han Y, Mao F, Wu Y, Fu X, Zhu X, Zhou S, Zhang W, Sun Q,Zhao Y*. Prognostic role of C-reactive protein in breast cancer: a systematic review and meta-analysis.Int J Biol Markers.
12.Fu X, Han Y, Wu Y, Zhu X, Lu X, Mao F, Wang X, He X, Zhao Y,Zhao Y*. Prognostic role of microRNA-21 in various carcinomas: a systematic review and Meta-analysis.Eur J Clin Invest.
13.Wu Y,Zhao Y*. Editorial Comment to Erythrocyte sedimentation rate kinetics as a marker of treatment response and predictor of prognosis in Chinese metastatic renal cell carcinoma patients treated with sorafenib.Int J Urol.
14.Li D,Zhao Y, Liu C, Chen X, Qi Y, Jiang Y, Zou C, Zhang X, Liu S, Wang X, Zhao D, Sun Q, Zeng Z, Dress A, Lin MC, Kung HF, Rui H, Liu LZ, Mao F, Jiang BH, Lai L*. Analysis of miR-195 and miR-497 expression, regulation and role in breast cancer.Clin Cancer Res.
15.Wu Y, Fu X, Zhu X, He X, Zou C, Han Y, Xu M, Huang C, Lu X,Zhao Y*. Prognostic role of systemic inflammatory response in renal cell carcinoma: a systematic review and meta-analysis.J Cancer Res Clin Oncol.
16.Li H,Zhao Y, Zhou S, Heng CK. Serum amyloid A activates peroxisome proliferator-activated receptor γ through extracellularly regulated kinase 1/2 and COX-2 expression in hepatocytes. Biochemistry.
17.Zhao Y, Chan MY, Zhou S, Heng CK. Effects of atherogenic diet and atorvastatin treatment on gene expression profiles in the C57BL/6J mouse liver. Gene Expr.
18.Zhao Y, Zhou S, Heng CK. Celecoxib inhibits serum amyloid a-induced matrix metalloproteinase-10 expression in human endothelial cells. J Vasc Res.
19.Chan MY,Zhao Y, Heng CK. Sequential responses to high-fat and high-calorie feeding in an obese mouse model. Obesity (Silver Spring).
20.Zhao Y, Zhou S, Heng CK. Impact of serum amyloid A on tissue factor and tissue factor pathway inhibitor expression and activity in endothelial cells. Arterioscler Thromb Vasc Biol.
21.石學桂,趙宇嵐*,王秋傑。血清澱粉樣蛋白A通過NFκB途徑誘導人臍靜脈內皮細胞E-選擇素的表達。《南京醫科大學學報(自然科學版)》。

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