《藥品快速檢測技術研究與套用（英文版）》是2019年化學工業出版社出版的圖書，作者是金少鴻。
基本介紹
- 書名：藥品快速檢測技術研究與套用（英文版）
- 作者：金少鴻
- 類別：醫學
- 出版社：化學工業出版社
- 出版時間：2019年06月
- 定價：¥298.00
- 開本：16 開
- 裝幀：精裝
- ISBN：9787122338532
編輯推薦,內容簡介,作者簡介,目錄,
編輯推薦
本書是“十三五”國家重點出版項目，書中內容具有原創性，對推廣藥品快檢技術有積極意義。
內容簡介
《藥品快速檢測技術的研究與套用（英文版）》為國家十三五重點出版物，對化學藥品的快速檢測理論與方法進行了詳細的闡述,收錄了化學藥品近紅外快速分析技術和HPLC的快速檢測方法。本書由權威部門編寫,內容原創。適用於從事藥物質量監督與管理的人員。
作者簡介
金少鴻，中國食品藥品檢定研究院，前副所長、研究員。從事化學藥品檢定工作30多年，是我國藥品檢定方面的專家。曾任中國藥品生物製品檢定所常務副所長、國家食品藥物監督管理局藥品評價中心主任等職務。從事藥品質量分析研究30年中，共獲國家科技進步獎3項，省部級科技進步獎8項。擔任中國藥學會理事、中國藥學會抗生素分科學會副主任委員、中國藥典委員會抗生素專業委員會主任委員、國家藥品監督管理局藥品審評專家、農業部獸用藥品審評審員、WHO西太區耐藥性監測網監測員、世界衛生組織國際藥典和藥品專家委員會委員。同時，兼任《中國抗生素雜誌》、《藥物分析雜誌》、《中國藥事》、《中國新藥雜誌》、《中國抗感染化療雜誌》、《中國臨床藥理學雜誌》等雜誌編委。
目錄
Rapid Analysis of Chemical Drugs Using the Near-infraredSpectroscopic Technology
Chapter 1 NIR Spectrometer / 7
Classification and Characteristics of NIR Spectrometer /7
Key Performance Indicators of NIR Spectroscopic Instrument / 11
Acquisition of NIR Spectrum / 16
NIR Spectrometer in Mobile lab / 17
Chapter 2 Introduction Near-infrared Analysis Methods / 20
Spectral Data Preprocessing Methods / 21
Qualitative Analysis Method / 25
Cluster Analysis / 31
Quantitative Analysis / 35
Conformity Test Analysis / 45
Correlation Coefficient Analysis / 49
Methods of Model Transfer / 52
Chapter 3 Application of NIR Methods in Drug Analysis / 58
Analysis of Antibiotics Using NIR Methods / 59
CASE STUDY 1 Establishment of Qualitative NIR Modelsfor the Analysis of Cephalosporin Injection Powder Products / 61
CASE STUDY 2 Rapid Determination of Cefuroxime SodiumContent Using NIR Analysis / 66
CASE STUDY 3 Construction of a Universal NIR Model forQuantitative Analysis of Cefradine Capsules / 73
CASE STUDY 4 Development of a Universal NIR Model forQuantitative Analysis of Phenoxymethylpenicillin Potassium Tablets / 79
CASE STUDY 5 Universal NIR Models for the QuantitativeAnalysis of Ceftriaxone and Water Contents in Ceftriaxone Sodium InjectionProducts / 85
Analysis of Chemical Drugs Using NIR Methods / 96
CASE STUDY 6 Construction of a Quantitative Model forSimvastatin Tablets / 98
CASE STUDY 7 NIR Models for Quantitative Analysis ofAminosalicylate and Water Contents in Sodium Aminosalicylate Injections / 102
CASE STUDY 8 Rapid Analysis of PotassiumDehydroandrographolide Succinate Injection Using NIRDRS / 108
CASE STUDY 9 NIR Identification and Analysis ofCompound Paracetamol and Amantadine Hydrochloride Tablets / 115
Application of NIR Spectroscopy in the Analysis of Traditional ChineseMedicines (TCM) / 120
CASE STUDY 10 Establishment of a Qualitative NIR Modelfor Cortex Magnoliae officinalis / 122
CASE STUDY 11 Analysis of Water Content in LiuweiDihuang Pills Using NIR Spectroscopy / 129
CASE STUDY 12 Qualitative Analysis of Different Brandsof Jianwei Xiaoshi Tablets Using NIR Spectroscopy / 131
CASE STUDY 13 Identification of Decoction Pieces ofCommon Yam Rhizome by NIR Method / 133
NIR Analysis of Illegal Additives in Medicinal Products / 143
CASE STUDY 14 Illegal Addition of Sildenafil Citrateinto Chinese Patent Medicine / 144
CASE STUDY 15 Norfloxacin Addition in LopermideHydrochloride Capsules / 146
CASE STUDY 16 NIR Correlation Analysis of IllegalAdded Phenformin Hydrochloride in Chinese Patent Medicines / 147
NIR Analysis of Liquid Formulations / 152
CASE STUDY 17 Construction NIR Quantitative Model forGlucose Injection / 154
Applications of NIR Methods on Mobile Laboratory Vehicles / 161
CASE STUDY 18 The Establishment and Application ofBlank Models Used for Spectra Comparison / 164
CASE STUDY 19 Establishment and Application of theCharacteristic Spectral Range Screening Method / 171
Chapter 4 Prospect of NIR Analysis Methods / 184
Development Prospect of NIR Analytical Instruments /185
Prospect of the Application of NIR Analysis Method /186
Prospect of NIR Analysis Methods being Listed in the National Drug Standards ofDifferent Countries / 190
References / 192
Rapid HPLC Forensic Analysis of Chemical Medicines
Chapter 5 Basic Principles and Methods for Rapid HPLCAnalysis / 202
Identification / 202
Content Determination / 202
Establishment and Validation of the Rapid HPLC Forensic Method / 203
Chapter 6 Applications of Rapid HPLC Analysis / 220
β-lactam Antibiotics / 221
Macrolide Antibiotics / 257
Quinolone Antibiotics / 276
Adrenocortical Hormone Drugs / 290
Sex Hormone Drugs / 306
Antidiabetic Drugs / 318
Calcium Channel Blockers / 332
Chapter 7 Progress of Rapid HPLC Analysis / 347
Establishment of Reference Database and Applications /347
Rapid Analysis by LC-MS / 349
References / 353
