董琳，女，四川人，博士，四川大學華西藥學院教授，博士生導師。
基本介紹
- 中文名：董琳
- 畢業院校：中國科學院成都有機化學研究所
- 學位/學歷：博士
- 性別：女
人物經歷,獲獎情況,研究方向,科研項目,發表論文,
人物經歷
1994-1998 鄭州大學化學系，化學專業，理學學士
2001-2006 中國科學院成都有機化學研究所，有機化學專業，碩博連讀，師從龔流柱教授
2006-2009 澳大利亞昆士蘭大學化學系，博士後，師從Craig M. Williams教授
2009-2011 新加坡科技研究局化學與工程科學研究院，研究科學家，師從著名化學家K. C. Nicolaou 教授
2011-2016 四川大學華西藥學院，副教授
2016-至今 四川大學華西藥學院，教授
獲獎情況
1、2012年 四川省引進海外高層次人才“百人計畫”，四川省特聘專家
2、2012年 四川大學優秀青年骨幹教師獎勵
3、2014年 大學生課外科技實踐活動優秀指導教師
4、2016年 四川大學唐立新優秀學者獎
研究方向
1、有機合成方法學研究
2、天然產物與藥物合成
科研項目
1、2013-2015 國家自然科學基金-青年基金
2、2016-2019 國家自然科學基金-面上項目
發表論文
[1] Liu, C.-F.; Zhang, G.-T.; Sun, J.-S.; Dong, L.*, “Access to π-conjugated azaindole derivatives via rhodium(III)-catalyzed cascade reaction of azaindoles and diazo compounds”, Org. Biomol. Chem. 2017, 15, 2902–2905.
[2] Xia, Y.-Q.; Dong, L.*, “Ruthenium(II)-Catalyzed Indolo[2,1-a]isoquinolines Synthesis by Tandem C−H Allylation and Oxidative Cyclization of 2-Phenylindoles with Allyl Carbonates”, Org. Lett., 2017, 19, 2258−2261.
[3] Zhang, G.-T.; Dong, L.*, “Synthesis of Polycyclic Amides via Tandem RhIII-Catalyzed C-H
Activation and Annulation from Dioxazolones and Alkynes”, Asia. J. Org. Chem. 2017, 6, 812 – 816.
[4] Wu, L.; Dong, L.*, “The application of Morita-Baylis-Hillman reaction: Synthetic studies on perophoramidine”, Tetrahedron 2017, 73, 3966-3972.
[5] Li, S.-S.; Liu, C.-F.; Zhang, G.-T.; Xia, Y.-Q.; Li, W.-H.; Dong, L.*, “A Convenient One-Pot Route to Screw-Shaped [5]Azahelicenes via Rhodium(III)-Catalyzed Multiple C-H Bond Activation”, Chem. Asia. J. 2017, 12, 415-418.
[6] Li, S.-S.; Xia, Y.-Q.; Liu, C.-F.; Zhang, G.-T.; Su, F.; Zhang, X.-M.; Dong, L.*, “Diverse Reactivity in a Rhodium(III)-Catalyzed Vinylic sp2 C–H Bond Functionalization: Synthesis of Fused Polycyclic Heteroarenes or Conjugated Dienes”, Adv. Synth. Catal. 2016,358(23), 3724 –3729.
[7] Lin, H.; Dong, L.*, “One-Pot Synthesis of Decahydropyrene via Tandem C−H Activation/Intramolecular Diels−Alder/1,3-Dipolar Cycloaddition”; Org. Lett., 2016, 18, 5524−5527.
[8] Li, S.-S.; Xia, Y.-Q.; Hu, F.-Z.; Liu, C.-F.; Su, F.; Dong, L.*, “Ir-Catalyzed One-Pot Cascade ynthesis of Pentacyclic-Fused Carbazoles from Indoles and Diazoes”, Chem. Asia. J. 2016, 11, 3165 – 3168.
[9] Li, W.-H.; Wu, L.; Li, S.-S.; Liu, C.-F.; Zhang, G.-T.; Dong, L.*, “Rhodium-Catalyzed Hydrogen-Releasing ortho-Alkenylation of 7-Azaindoles”, Chem. Eur. J. 2016, 22(50), 17926– 17929.
[10] Zhu, Y.-Q.; Qin, L.; Song, Q.; Su, F.; Xu, Y.-J.; Dong, L.*, “Rhodium(III)-catalyzed ortho-alkenylation using a cyclic N-phosphoryl ketimine as the directing group”, Org. Biomol. Chem. 2016, 14, 9472–9475.
[11] Li, S.-S.; Wu, L.; Qin, L.; Zhu, Y.-Q.;Su, F.; Xu, Y.-J.; Dong, L.*, “Iridium(III)-Catalyzed Tandem [3 + 2] Annulation: Synthesis of Spirocyclic Phosphoramide Derivatives”,Org. Lett., 2016, 18 (17), 4214–4217.
[12] Li, S.-S.; Li, W.-H.; Zhang, G.-T.; Xia, Y.-Q.; Liu, C.-F.; Su, F.; Zhang, X.-M.; Dong, L.*, “One-pot construction of fused polycyclic heteroarenes involving 7-azaindoles and α,β-unsaturated ketones”, Org. Biomol. Chem., 2016, 14, 7859–7863.
[13] Wang, C.-Q.; Zhang, W., Lin, H.; Su, F.; Dong, L.*, “Synthesis of Isoquinolinium Salts via Rh(III)-catalyzed Oxidative Annulation between Aldehyde Imines and Alkynes”, HETEROCYCLES, 2016, 92（9）,1674-1686.
[14] Li, S.-S.; Lin, H.; Liu, C.-F.; Xia, Y.-Q.; Zhang, X.-M.; Dong, L.*, “Rhodium-Catalyzed Tandem Annulation Reactions of 7-Azaindoles with Electron-Deficient Olefins via Double C-H Activation”, Adv. Synth. Catal. 2016, 358, 1595 –1601.
[15] Li, S.-S.; Liu, C.-F.; Xia, Y.-Q.; Li, W.-H.; Zhang, G.-T.; Zhang, X.-M.; Dong, L.*, “A unique annulation of 7-azaindoles with alkenyl esters to produce π-conjugated 7-azaindole derivatives”, Org. Biomol. Chem., 2016, 14, 5214–5218.
[16] Li, S.-S.; Qin, L.; Dong, L.*, “Rhodium-catalyzed C–C coupling reactions via double C–H activation”, Org. Biomol. Chem., 2016,14, 4554-4570.
[17] Li, S.-S.; Wang, C.-Q.; Li, W.-H.; Zhang, X.-M.; Dong, L.*, “Rhodium-catalyzed selective oxidative coupling of 7-azaindoles”, Tetrahedron 2016, 72, 2581-2586.
[18] Zhang, W., Wang, C.-Q.; Lin, H.; Dong, L.*, Xu, Y.-J, “Synthesis of Mesoionic Isoquinolines by Rhodium(III)-Catalyzed C-H Activation”, Chem. Eur. J. 2016, 22, 907-910.
[19] Li, S.-S.; Wang, C.-Q.; Lin, H.; Zhang, X.-M.; Dong, L.*, “Rhodium(III)-catalyzed C–C coupling of 7-azaindoles with vinyl acetates and allyl acetates”, Org. Biomol. Chem., 2016, 14, 229–237.
[20] Zhu, Y.-Q.;Dong, L.*, “One-Pot Synthesis of Polysubstituted Spirofluorene−Indene via Ru(II)-Catalyzed [3 + 2] Annulation and Intramolecular Friedel−Crafts Cyclization”, J. Org. Chem. 2015, 80 (20), 9973−9979
[21] Lin, H.; Li, S.-S.; Dong, L.*, “Synthesis of indoles and polycyclic amides via ruthenium(II)-catalyzed C-H activation and annulation”, Org. Biomol. Chem. 2015, 13, 11228-11234
[22] Li, S.-S.; Wang, C.-Q.; Lin, H.; Zhang, X.-M.; Dong, L.*, “Rhodium(III)-Catalyzed Oxidative Annulation of 7‑Azaindoles and Alkynes via Double C−H Activation” Org. Lett. 2015, 17, 3018-3021.
[23] Huang, J.-R.; Qin, L.; Zhu, Y.-Q.; Song, Q.;Dong, L.* “Multi-site Cyclization via Initial C-H Activation Using Rhodium(III) Catalyst: Rapid Assembly of Frameworks Containing Indoles and Indolins” Chem. Comm. 2015, 51, 2844-2847.
[24] Li, S.-S.; Lin, H.; Zhang, X.-M.; Dong, L.* “Ruthenium-Catalyzed Direct C3 Alkylation of Indoles with α,β-Unsaturated Ketones”, Org. Biomol. Chem. 2015, 13,1254-1263.
[25] Zhang, W.; Zhang, Q.-R.; Dong, L.* “Rhodium-catalyzed [2+2+2] cycloaddition reactions of terminal alkynes with N-sulfonyl ketimines”, Tetrahedron Letters 2015, 56, 546–548.
[26] Zhang, Q.-R.; Huang, J.-R.; Zhang, W.; Dong, L.* “Highly Functionalized Pyridines Synthesis fromN-Sulfonyl Ketimines and Alkynes Using N-S Bond as an Internal Oxidant”, Org. Lett. 2014, 16, 1684-1687.
[27] Huang, J.-R.; Song, Q.; Zhu, Y.-Q.; Qin, L.; Qian, Z.-Y.; Dong, L.* “Rhodium(III)-Catalyzed Three-Component Reactions of Imines, Alkynes, and Aldehydes via C–H Activation”, Chem. Eur. J. 2014, 20, 16882-16886.
[28] Dong, L.*; Qu, C.-H.; Huang, J.-R.; Zhang, W.; Zhang, Q.-R.; Deng, J.-G. “Rhodium-catalyzed Spirocyclic Sultam Synthesis by [3+2] Annulation with Cyclic N-Sulfonyl Ketimines and Alkynes”,Chem. Eur. J. 2013, 19, 16537-16540.
[29] Dong, L.*; Huang, J.-R.; Qu, C.-H.; Zhang, Q.-R.; Zhang, W.; Han, B.; Peng, C.* “Rhodium(III)-catalyzed vinylic sp2 C–H bond functionalization: efficient synthesis of pyrido[1,2-α]-benzimidazoles and imidazo[1,2-α]pyridines”, Org. Biomol. Chem. 2013, 11, 6142–6149.
[30] Huang, J.-R.; Zhang, Q.-R.; Qu, C.-H.; Sun, X.-H.; Dong, L.* Chen. Y.-C.* “Rhodium(III)-Catalyzed Direct Selective C(5)-H Oxidative Annulations of 2-Substituted Imidazoles and Alkynes by Double C-H Activation”, Org. Lett. 2013, 15, 1878-1881.
[31] Huang, J.-R.; Dong, L.*; Han, B.; Peng, C.; Chen. Y.-C. “Synthesis of Aza-Fused Polycyclic Quinolines via Double C-H Bond Activations”, Chem. Eur. J. 2012, 18, 8896-8898.
