范永強，男，博士，東北大學生命科學與健康學院教授、博士生導師。
基本介紹
- 中文名：范永強
- 職業：教師
- 畢業院校：大連理工大學
- 學位/學歷：博士
- 專業方向：生物化工
- 任職院校：東北大學
人物經歷,學習經歷,工作經歷,研究方向,發表論文,
人物經歷
學習經歷
2002-2006大連理工大學生物工程專業，學士
2006-2012大連理工大學環境科學與生命學院生物化工專業，博士
2013-2018德克薩斯州立大學休斯頓健康中心，博士後
工作經歷
2018-至今 東北大學生命科學與健康學院，教授，博士生導師
研究方向
本課題組著重於研究蛋白質翻譯的質量監控，利用分子生物學、基因組學、合成生物學以及生物信息學等學科手段在以下領域解決具體的科學問題：（1）病原微生物的致病因子及其致病機理；（2）病原微生物的耐藥性機理；（3）病原微生物與宿主的相互作用；（4）通過對工業微生物及環境微生物進行改造，與金屬材料學科進行合作交叉研究，結合合成生物學，進行微生物金屬腐蝕機理的研究以及新型生物材料的研發。
發表論文
1. Yongqiang Fan, Christopher R. Evans, Kalyn J. Weiss,Jiqiang Ling. (2018).Errors during Gene Expression: Single-Cell Heterogeneity, Stress Resistance, and Microbial-Host Interactions. mBio. 9(4): pii: e01018-18.
2. Yongqiang Fan, Christopher R. Evans, Karl W. Barber, Kinshuk Banerjee, Kalyn J. Weiss, William Margolin, Oleg A. Igoshin, Jesse Rinehart, Jiqiang Ling. (2017). Heterogeneity of Stop Codon Readthrough in Single Baterial Cells and Implications for Population Fitness. Molecular Cell.67(5):826-836.
3. Yongqiang Fan, Christopher R. Evans, Jiqiang Ling. (2017). Rewiring protein synthesis: From natural to synthetic amino acids. Biochimica et Biophysica Acta(BBA) – General Subjects, 01.014.
4. Yongqiang Fan, Christopher R. Evans, Jiqiang Ling. (2016). Reduced protein synthesis fidelity inhibits flagellar biosynthesis and motility. Scientific Report 6, 30960.
5. Yongqiang Fan, Jiang Wu, Matthew H. Ung, Nicholas De Lay, Chao Cheng and JiqiangLing. (2015). Protein mistranslation protects bacteria against oxidative stress. Nucleic Acids Research, 43(3):1740-1748.
6. Jiang Wu, Yongqiang Fan, Jiqiang Ling. (2014). Mechanism of oxidant-induced mistranslation by threonyl-tRNA synthetase. Nucleic Acids Research, 42(10):6523-6531.
7. Yongqiang Fan, Hongjian Liu, Li Yan, Yushi Luan, JunMo Yang, Haimeng Zhou, Yulong Wang. (2013). Optimized transformation of Streptomyce sp. ATCC 39366 producing leptomycin by electroporation. The Journal of Microbiology, 51(3):318-22.
8.Yongqiang Fan, Hongjian Liu, Chang Li, Yushi Luan, JunMo Yang, Yulong Wang. (2013). Inactivation of recombinant human brain-type creatine kinase during denaturation by guanidine hydrochloride in a macromolecular crowding system. Applied Biochemistry and Biotechnology, 169(1): 268-280.
9. Yongqiang Fan, Jinhyuk Lee, Sangho Oh, Hongjian Liu, Chang Li, Yushi Luan, JunMo Yang, Haimeng Zhou, ZhirongLü, Yulong Wang. (2012). Effects of osmolytes on human brain-type creatine kinase folding in dilute solutions and crowding systems. International Journal of Biological Macromolecules, 51(5): 845-858.
10. Yongqiang Fan, Hongjian Liu, Chang Li, Yushi Luan, JunMo Yang, Yulong Wang. (2012). Effects of macromolecular crowding on refolding of recombinant human brain-type creatine kinase. International Journal of Biological Macromolecules, 51(1-2): 113-118.
11. Yongqiang Fan, Yushi Luan, Lijia An, Kun Yu. (2008). Arbuscular mycorrhizae formed by Penicillium pinophilum improve the growth, nutrient uptake and photosynthesis of strawberry with two inoculum-types. Biotechnol. Lett., 30(8): 1489-1494.
12.Yongqiang Fan, Yushi Luan, Lu Feng. (2008). Selection of antagonistic microorganisms against blueberry spot disease pathogen and optimization of fermentation conditions. Journal of Fruit Science, 25(3): 426-430.
13. Lu Feng, Yushi Luan, Yongqiang Fan. (2007). The inhibiting effects of extracts from the ginkgo (ginkgo biloba L.) testas against pathogen Cylindrocladiumcolhounii. Bulletin Botanical Research, 27(4): 509-512.
14. Lu Feng, Yushi Luan, Yongqiang Fan, Han Zhong. (2007). Pathogen indentification of leaf spot disease on blueberry. Journal of Northeast Agricultural University, 38(5): 614-618.
