羅增偉，博士，華中科技大學同濟藥學院講師。
基本介紹
- 中文名：羅增偉
- 畢業院校：武漢大學
- 學位/學歷：博士
- 職業：教師
- 任職院校：華中科技大學
個人經歷,學術成果,
個人經歷
1998.9~2002.7 南昌大學化學系獲學士學位
2002.9~2007.12 武漢大學有機化學專業獲博士學位
2008.1~2009.12 上海藥明康德
2010.1~2012.12 華中科技大學同濟藥學院天然藥物化學教研室/湖北省天然藥物化學與資源評價重點室 博士後
2013.4至今 華中科技大學同濟藥學院天然藥物化學教研室/湖北省天然藥物化學與資源評價重點室 講師
學術成果
主持與參與的項目
1． 國家自然科學基金《新型PTP1B抑制劑金線蓮苷構效關係及降糖作用機制研究》，25萬（2012.01~2014.12），主持
2．國家重大新藥創製專項課題《化藥一類降血糖新藥KD10臨床前研究》500萬，2011.1-2013.12，參與
3．武漢長聯來福生化藥業有限責任公司課題《新型PTP1B抑制劑Kinsenoside結構類似物一類新藥研究》250萬元，2010.1-2014.12，參與
4．國家自然科學基金《基於抑制Streptomyces 85E氣生菌絲生成從照山白中尋找新穎蛋白激酶抑制劑先導化合物》，25萬(,2011.01~2013.12)，參與
5．國家自然科學基金《黃芫花中抗腫瘤二萜活性成分及抑制腫瘤侵襲轉移作用機制研究》，35萬(,2011.01~2013.12)，參與
發表的文章
(1) Yuan, Ming; Chen, Li; Wang, Junwei; Chen, Shenjie; Wang, Kongchao; Xue, Yongbo; Yao, Guangmin;Luo, Zengwei*; Zhang, Yonghui*. Transition-Metal-Free Synthesis of Phenanthridinones from Biaryl-2-oxamic Acid under Radical Conditions.Organic Letters,2015,
(2) Zengwei Luo,Bo Yang, Cheng Zhong, Fang Tang, Min Yuan, Yongbo Xue, Guanmin Yao, Jingwen Zhang*, Yonghui Zhang* . A dual-channel probe for selective fluoride determination and application in live cell imaging.Dyes and Pigments,2013,
(3) Zengwei Luo#, Fuqian Wang#, Jinwen Zhang, Xingyao Li, Mengke Zhang, Xincai Hao, Yongbo Xue, Yan Li, F. David Horgen, Guangmin Yao*, and Yonghui Zhang*. Cytotoxic Alkaloids from the Whole Plants ofZephyranthes candida,Journal of Natural Products,2012,
(4) Zengwei Luo,Baohua Li, Xiantao Fan, Kai Hu, Xiaojun Wu, Enqin Fu*.Novel chiral solvating agents derived from natural amino acid: enantiodiscrimination for chiral α-arylalkylamines,Tetrahedron Letters, 2007,
(5) Zengwei Luo,Cheng Zhong, Xiaojun Wu, Enqin Fu*.Novel amphiphilic chiral receptors as efficient chiral solvating agents for both lipophilic and hydrophilic Carboxylic Acid,Tetrahedron Letters, 2008,
(6) Yuanyuan Lu(#), Yongbo Xue(#)(*), Junjun Liu, Guangmin Yao, Dongyan Li, Bin, Sun, Jinwen Zhang, Yanfei Liu, Changxing Qi, Ming Xiang,Zengwei Luo, Guang Du(*), Yonghui Zhang(*), (±)-Acortatarinowins A–F, Norlignan, Neolignan, and Lignan Enantiomers from Acorus tatarinowii.Journal of Natural Products,2015,
(7) Hucheng Zhu(#), Chunmei Chen(#), Yongbo Xue(#), Qingyi Tong, Xiao-Nian Li, Xintao Chen, Jianping Wang, Guangmin Yao,Zengwei Luo, and Yonghui Zhang(*), Asperchalasine A, a Cytochalasan Dimer with an Unprecedented Decacyclic Ring System, from Aspergillus flavipes.Angewandte Chemie-International Edition,2015,
(8) Hucheng Zhu(#), Chunmei Chen(#), Qingyi Tong, Xintao Chen, Jing Yang, Junjun Liu, Bin Sun, Jianping Wang, Guangmin Yao,Zengwei Luo, Yongbo Xue(*), and Yonghui Zhang(*), Hyperisampsins H−M, Cytotoxic Polycyclic Polyprenylated Acylphloroglucinols from Hypericum sampsonii,Scientific Reports,2015, (Accepted).
(9) Liang Lei(#), Yong-bo Xue(#), Zhong Liu, Si-si Peng, Yan He, Yang Zhang, Rong Fang, Jian-ping Wang,Zeng-wei Luo, Guang-minYao, Jin-wen Zhang, Geng Zhang, Hong-ping Song(*), Yong-hui Zhang(*), Coumarin derivatives from Ainsliaea fragrans and their anticoagulant activity,Scientific Reports,2015,
(10) Yongji Lai, Tingting Liu, Rongjian Sa, Xialan Wei, Yongbo Xue, Zhaodi Wu,Zengwei Luo, Ming Xiang, Yonghui Zhang(*), and Guangmin Yao(*), Neolignans with a Rare 2-Oxaspiro[4.5]deca-6,9-dien-8-one Motif from the Stem Bark of Cinnamomum subavenium,Journal of Natural Products, 2015,
(11) Chunmei Chen, Jianping Wang, Junjun Liu, Hucheng Zhu, Bin Sun, Jing Wang, Jinwen Zhang,Zengwei Luo, Guangmin Yao, Yongbo Xue(*), and Yonghui Zhang(*), Armochaetoglobins A−J: Cytochalasan Alkaloids from Chaetomium globosum TW1-1, a Fungus Derived from the Terrestrial Arthropod Armadillidium vulgare, Journal of Natural Products, 2015,
(12) Chunmei Chen, Hucheng Zhu, Jianping Wang, Jing Yang, Xiao-Nian Li, Jing Wang, Keliang Chen, Yanyan Wang,Zengwei Luo, Guangmin Yao, Yongbo Xue(*), and Yonghui Zhang(*), Armochaetoglobins K–R, Anti-HIV Pyrrole-based Cytochalasans from Chaetomium Globosum TW1-1,European Journal of Organic Chemistry, 2015:
(13) Dongyan Li, Hucheng Zhu, Changxing Qi, Yongbo Xue(*), Guangmin Yao,Zengwei Luo, Jianping Wang, Jinwen Zhang, Guang Du(*), and Yonghui Zhang(*), Two New adamantyl-Like polyprenylated Acylphloroglucinols from Hypericum attenuatum Choisy, Tetrahedron Letters, 2015,
(14) Chunmei Chen(#), Hucheng Zhu(#), Xiao-Nian Li, Jing Yang, JianpingWang, Gentao Li, Yan Li, Qingyi Tong, Guangmin Yao,Zengwei Luo, Yongbo Xue(*), and Yonghui Zhang(*), Armochaeglobines A and B, Two New Indole-Based Alkaloids from the Arthropod-Derived Fungus Chaetomium globosum,Organic Letters, 2015,
(15) Hucheng Zhu, Chunmei Chen., Jing Yang, Xiao-Nian Li, Junjun Liu, Bin Sun, Sheng-Xiong Huang, Dongyan Li, Guangmin Yao,Zengwei Luo, Yan Li, Jinwen Zhang, Yongbo Xue(*), and Yonghui Zhang(*), Bioactive Acylphloroglucinols with Adamantyl Skeleton from Hypericum sampsonii,Organic letters, 2014,
(16) Zhengxi Hu, Jianping Wang, Xiaobin Bi, Jinwen Zhang, Yongbo Xue(*), Yingda Yang,Zengwei Luo, Guangmin Yao, and Yonghui Zhang(*), Colletotrichumine A, a novel indole-pyrazine alkaloid with an unprecedented C16N3-type skeleton from cultures of Colletotrichum capsici,Tetrahedron Letters, 2014,
(17) Junfen Zeng, Yongbo Xue, Penghua Shu, Huiqin Qian, Rongjian Sa, Ming Xiang, Xiao-Nian Li,Zengwei Luo, Guangmin Yao(*), and Yonghui Zhang(*), Diterpenoids with Immunosuppressive Activities from Cinnamomum cassia,Journal of Natural Products, 2014,
(18) Hucheng Zhu(#), Lijun Huan(#), Chunmei Chen, Jing Yang, Jiangbo He, Yong Chen, Guangmin Yao,Zengwei Luo,Yongbo Xue(*), and Yonghui Zhang(*), A Pair of Unprecedented Cyclohexylethanoid Enantiomers Containing Unusual Trioxabicyclo[4.2.1]nonane Ring from Clerodendrum bungei,Tetrahedron Letters, 2014,
(19) 25. Heng Zheng, Qiong Chen, Mengke Zhang, Yongji Lai, Liang Lei, Penghua Shu, Jinwen Zhang, Yongbo Xue,Zengwei Luo, Yan Li, Guangmin Yao(*), and Yonghui Zhang(*), Cytotoxic ent-Kaurane Diterpenoids from Salvia cavaleriei,Journal of Natural Products, 2013,
(20) Mengke Zhang, Yan Zhu, Guanqun Zhan, Penghua Shu, Rongjian Sa, Liang Lei, Ming Xiang, Yongbo Xue,Zengwei Luo, Qian Wan, Guangmin Yao(*), and Yonghui Zhang(*), Micranthanone A, a New Diterpene with an Unprecedented Carbon Skeleton from Rhododendron micranthum,Organic Letters, 2013,
