章小清

章小清

同濟大學醫學院教授,博士生導師。主要研究聚焦人胚胎幹細胞或人工誘導多能幹細胞的神經定向分化、人神經發育、神經系統疾病與神經再生。在國際性學術期刊發表SCI論文30餘篇,包括Cell、CellStem Cell、Development、CellResearch、Stem Cell Reports 等國際著名雜誌。

基本介紹

  • 中文名:章小清
  • 職業:教師
  • 研究方向:幹細胞定向神經分化 
  • 職稱:教授 
  • 性別:男
主要任職,代表性論文,

主要任職

同濟大學特聘教授、博導;
國家重大科學研究計畫(2012年)和國家重點研發計畫(2018年)首席科學家;
上海市神經再生高校重點實驗室負責人;
上海市優秀學術帶頭人;
入選上海市“浦江人才”計畫、“曙光”計畫、教育部“新世紀優秀人才”支持計畫。

代表性論文

1. Smad5 actsas an intracellular pH messenger and maintains bioenergetic homoeostasis. CellResearch 2017, 27(9):1083-1099.
2. Nucleosome eviction along withH3K9ac deposition enhances Sox2 binding during human neuroectodermalcommitment. Cell Death Differ 2017, 24(6):1121-1131.
3. Dysregulation of the SIRT1/OCT6Axis Contributes to Environmental Stress-induced Neural Induction Defects. StemCell Reports 2017, 8(5):1270-1286.
4. Targeted differentiation ofregional ventral neuroprogenitors and related neuronal subtypes from humanpluripotent stem cells. Stem Cell Reports. 2016.7(5):941-954.
5. Efficient CRISPR/Cas9-mediated versatile, predictable, and donor-free geneknockout in human pluripotent stem cells. Stem Cell Reports. 2016.7(3):496-507.
6. The dorsoventral patterning of human forebrain follows an activation/transformationmodel. Cerebral Cortex. 2016. Online.
7. Smad2 and Smad3 have differential sensitivity in relaying TGFbeta signalingand inversely regulate early lineage specification. Scientific Reports.2016.6:21602.
8. Pax6 is a human neuroectodermcell fate determinant. Cell Stem Cell.2010. 7(1): 90-100.
9. Hypothalamic IKKbeta/NF-kappa B and ER stress link overnutrition to energyimbalance and obesity. Cell. 2008.135(1): 61-73.

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