《病理生理學》是2018年清華大學出版社出版的圖書。
基本介紹
- 中文名：病理生理學
- 作者：[美] 休·E.許特（Sue E.Huether） 等
- 出版時間：2018年10月1日
- 出版社：清華大學出版社
- ISBN：9787302463382
內容簡介,圖書目錄,作者簡介,
內容簡介
《病理生理學》是一門研究疾病發生、發展和轉歸規律的基礎醫學學科。它既是一門醫學基礎學科，也是一門醫學交叉學科。由於它是運用生理學、生物化學、微生物學、免疫學等基礎學科的相關知識解釋疾病發生機制，所以被稱為溝通基礎醫學與臨床醫學的橋樑。
圖書目錄
Contents
目.錄
Chapter 1
Altered Cellular and Tissue Biology…………………………………………………………………………… 1
Cellular Injury ………………………………………………………………………………………………………… 1
Cellular Death ……………………………………………………………………………………………………… 10
agIng anD altereD Cellular anD tIssue BIology …………………………………………………… 11
somatIC Death ……………………………………………………………………………………………………… 12
Chapter 2
Fluids and Electrolytes, Acids and Bases ………………………………………………………………… 13
DIstrIButIon of BoDy fluIDs anD eleCtrolytes ………………………………………………………… 13
alteratIons In Water movement …………………………………………………………………………… 15
soDIum, ChlorIDe, anD Water BalanCe …………………………………………………………………… 16
alteratIons In soDIum, ChlorIDe, anD Water BalanCe …………………………………………… 18
alteratIons In PotassIum anD other eleCtrolytes ………………………………………………… 21
aCID-Base BalanCe ………………………………………………………………………………………………… 27
aCID-Base ImBalanCes……………………………………………………………………………………………… 30
Chapter 3
Stress and Disease ……………………………………………………………………………………………… 33
hIstorICal BaCkgrounD anD general ConCePts ……………………………………………………… 33
the stress resPonse ………………………………………………………………………………………………… 37
stress, PersonalIty, CoPIng, anD Illness ………………………………………………………………… 46
Chapter 4
Biology of Cancer ……………………………………………………………………………………………… 50
CanCer termInology anD CharaCterIstICs……………………………………………………………… 50
the BIology of CanCer Cells …………………………………………………………………………………… 51
ClInICal manIfestatIons of CanCer ………………………………………………………………………… 61
DIagnosIs, CharaCterIzatIon, anD treatment of CanCer………………………………………… 63
Chapter 5
Cancer Epidemiology ………………………………………………………………………………………… 67
genetICs, ePIgenetICs, anD tIssue …………………………………………………………………………… 68
In utero anD early lIfe ConDItIons ………………………………………………………………………… 68
envIronmental-lIfestyle faCtors ………………………………………………………………………… 68
Chapter 6
Pain, Temperature and Sleep ………………………………………………………………………………… 80
PaIn ……………………………………………………………………………………………………………………… 80
temPerature regulatIon………………………………………………………………………………………… 86
sleeP ……………………………………………………………………………………………………………………… 90
Chapter 7
Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function ……………… 92
alteratIons In CognItIve systems …………………………………………………………………………… 92
alteratIons In CereBral hemoDynamICs ………………………………………………………………… 106
alteratIons In neuromotor funCtIon …………………………………………………………………… 109
Chapter 8
Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction ……… 113
Central nervous system DIsorDers ………………………………………………………………………… 113
PerIPheral nervous system anD neuromusCular junCtIon DIsorDers ……………………… 131
Chapter 9
Alterations of Hormonal Regulation ……………………………………………………………………… 133
meChanIsms of hormonal alteratIons…………………………………………………………………… 133
alteratIons of the hyPothalamIC-PItuItary system ……………………………………………… 134
alteratIons of thyroID funCtIon …………………………………………………………………………… 139
alteratIons of ParathyroID funCtIon …………………………………………………………………… 143
DysfunCtIon of the enDoCrIne PanCreas: DIaBetes mellItus …………………………………… 144
alteratIons of aDrenal funCtIon ………………………………………………………………………… 154
tumors of the aDrenal meDulla …………………………………………………………………………… 157
Chapter 10
Structure and Function of the Hematologic System …………………………………………………… 159
ComPonents of the hematologIC system ………………………………………………………………… 159
meChanIsms of hemostasIs ……………………………………………………………………………………… 165
antICoagulant system …………………………………………………………………………………………… 169
Chapter 11
Alterations of Hematologic Function……………………………………………………………………… 171
alteratIons of erythroCyte funCtIon …………………………………………………………………… 171
alteratIons of leukoCyte funCtIon ……………………………………………………………………… 179
hemorrhagIC DIsorDers anD alteratIons of Platelets anD CoagulatIon ……………… 185
Chapter 12
Regulation of Cardiovascular Function ………………………………………………………………… 194
the CIrCulatory system ………………………………………………………………………………………… 194
the systemIC CIrCulatIon ……………………………………………………………………………………… 197
Chapter 13
Alterations of Cardiovascular Function ………………………………………………………………… 205
DIseases of the arterIes ………………………………………………………………………………………… 205
manIfestatIons of heart DIsease …………………………………………………………………………… 225
shoCk …………………………………………………………………………………………………………………… 230
Chapter 14
Function of the Pulmonary System ……………………………………………………………………… 241
funCtIon of the Pulmonary system ………………………………………………………………………… 241
Chapter 15
Alterations of Pulmonary Function ……………………………………………………………………… 251
ClInICal manIfestatIons of Pulmonary alteratIons ……………………………………………… 251
Pulmonary DIsorDers …………………………………………………………………………………………… 258
Chapter 16
Function of the Renal and Urologic Systems …………………………………………………………… 280
regulatIon of renal BlooD floW …………………………………………………………………………… 280
kIDney funCtIon …………………………………………………………………………………………………… 281
tests of renal funCtIon ………………………………………………………………………………………… 285
Chapter 17
Alterations of Renal and Urinary Tract Function ……………………………………………………… 288
urInary traCt oBstruCtIon …………………………………………………………………………………… 288
urInary traCt InfeCtIon ………………………………………………………………………………………… 295
glomerular DIsorDers …………………………………………………………………………………………… 298
aCute kIDney Injury ……………………………………………………………………………………………… 301
ChronIC kIDney DIsease…………………………………………………………………………………………… 305
Chapter 18
Alterations of the Female Reproductive System ……………………………………………………… 311
Chapter 19
Alterations of Digestive Function ………………………………………………………………………… 331
DIsorDers of the gastroIntestInal traCt ……………………………………………………………… 331
DIsorDers of the aCCessory organs of DIgestIon …………………………………………………… 347
CanCer of the DIgestIve system ……………………………………………………………………………… 358
Chapter 20
Alterations of Musculoskeletal Function ………………………………………………………………… 362
musCuloskeletal InjurIes ……………………………………………………………………………………… 362
DIsorDers of Bones ………………………………………………………………………………………………… 371
DIsorDers of joInts ………………………………………………………………………………………………… 380
DIsorDers of skeletal musCle ………………………………………………………………………………… 394
musCuloskeletal tumors ……………………………………………………………………………………… 402
作者簡介
徐哲龍教授於1998年獲得日本山形大學醫學博士學位，1999年進入美國南阿拉巴馬大學進行博士後研究，2001年以研究員身份就職於美國北卡羅來納大學麻醉系，2006年升至助理教授，2011年被聘為“天津市特聘教授”及“‘211工程’特聘教授”，2012年被任命為“天津醫科大學基礎醫學院生理學與病理生理學系系主任”。主要研究方向為缺血心臟的保護機制，先後主持多項美國國立衛生研究院（NIH）基金課題及國家自然基金課題，以一作者或一通訊作者發表SCI論文30餘篇，被引用700多次，並在多個高水平雜誌擔任編委，如： Basic Research in Cardiology (IF 7.4)及Managing Editor for Frontiers in Bioscience (IF 3.7)。
