暨南大學基礎醫學院組織學與胚胎學系副教授，碩士生導師。2006年畢業於濟南大學生物技術系，2010年在佳木斯大學獲得醫學碩士學位，2013年在暨南大學獲得醫學博士學位。博士畢業後在暨南大學組織學胚胎學系從事教科研工作，同年12月進入暨南大學中西醫結合博士後流動站進行師資博士後研究，2016年出站。近年來主要研究方向為胚胎早期發育過程中的基因調控及先天性疾病的防治。主持國家自然科學基金、中國博士後基金、廣東省科技計畫項目等10餘項，獲得“廣州市珠江科技新星”等人才項目資助。在Cell Death & Disease、Mol Biol Cell、Cell Cycle、J Exp Biol等國際優秀雜誌發表論文近40篇。
基本介紹
- 中文名：王廣
- 國籍：中華人民共和國
- 民族：漢
- 出生地：山東省
- 出生日期：1985年
- 職業：教師
- 畢業院校：濟南大學；佳木斯大學；暨南大學
- 學位/學歷：博士
- 專業方向：胚胎早期發育與先天性疾病
[1] Gao L R, Li S ; Zhang J, Liang C, Chen E N ; Zhang S Y ; Chuai M ; Bao Y; Wang G*, Yang X*. Excess imidacloprid exposure causes the heart tube malformation of chick embryos. J Agric Food Chem, 64(47):9078-9088. 2016 (IF:2.857, JCR一區，通訊作者)
[2] Wang G, Yeung C K, Wong W Y, Zhang N, Wei Y F, Zhang J L, Yan Y, Wong C Y, Tang J J, Chuai M, Lee K K, Wang L J , Yang X*. Liver fibrosis can be induced by high salt intake through excess reactive oxygen species (ros) production. J Agric Food Chem, 64(7):1610-7. 2016 (IF:2.857, JCR一區，第一作者)
[3] Wang G., Huang W.Q., Cui S.D., Li S., Wang X.Y., Li Y., Chuai M., Cao L., Li J.C., Lu D.X.*, Yang X*. Autophagy is involved in high glucose-induced heart tube malformation. Cell Cycle. 14(5): 772-783. 2015 (IF:3.952,第一作者)
[4] Wang G., Li Y, Wang X.Y., Chuai M., Chan J.Y., Lei J., Münsterberg A., Lee K.K.*, Yang X*. Mis-expression of BRE gene in the developing chick neural tube affects neurulation and somitogenesis. Mol Biol Cell. 26(5): 978-92. 2015 (IF:4.037, 第一作者)
[5] Wang G., Li Y., Wang X. Y., Han Z., Chuai M., Wang L. J., Ho Lee K. K., Geng J. G. *, Yang X*. Slit/Robo1 signaling regulates neural tube development by balancing neuroepithelial cell proliferation and differentiation. Exp Cell Res 319 (8):1083-1093. 2013 (IF: 3.372,第一作者)
[6]Wang G., Zhong S, Zhang S.Y., Ma Z. L., Chen J. L., Lu W. H., ChengX, ChuaiM, Lee K K, Lu D.X.*, Yang X*. Angiogenesis is repressed by ethanol exposure during chick embryonic development. J Appl Toxicol. 2016 May;36(5):692-701. (IF: 2.722,第一作者)
[7]Wang G, Yeung C K, Zhang J L, Hu X W, Ye Y X, Yang Y X, Li J C, Lee K K, Yang X*, Wang L J*. High salt intake negatively impacts ovarian follicle development. Ann Anat, 200:79-87. 2015 (IF: 1.308,第一作者)
[8]Wang G., Zhang N., Wei Y F., Jin Y M, Zhang S Y., Cheng X., Ma Z L., Zhao S Z., Chen Y P., Chuai M, Hocher B., Yang X*. The impact of high salt exposure on cardiovascular development in the early chick embryo. J Exp Biol. 218(Pt 21):3468-77. 2015(IF: 2.914,第一作者)
[9] Yeung C K,Wang G, Yao Y, Liang J, Chung C Y, Chuai M, Lee K K*, Yang X*. BRE modulates granulosa cell death to affect ovarian follicle development and atresia in the mouse. Cell Death & Disease. Accepted. 2017(IF: 5.378, 共第一作者)
[10] Wang CJ, Wang G, Wang XY, Liu M, Chuai M, Lee KK, He XS, Lu DX, Yang X*. Imidacloprid Exposure Suppresses Neural Crest Cells Generation during Early Chick Embryo Development. 15;64(23):4705-15. J Agric Food Chem. 2016 (IF:2.857, JCR一區，共第一作者)
[11] Jin Y, Wang G, Han SS, He MY, Cheng X, Ma ZL, Wu X, Yang X*, Liu GS*. Effects of oxidative stress on hyperglycaemia-induced brain malformations in a diabetes mouse model. 10;347(1):201-11. Exp Cell Res, 2016. (IF:3.378,共第一作者)
[12] He MY, Wang G, Han SS, Jin Y, Li H, Wu X, Ma ZL, Cheng X, Tang X, Yang X*, Liu GS*. Nrf2 signaling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placenta. Open Biol. 6(7).pii: 160064. 2016 (IF:4.822,共第一作者)
[13] Liu M, Wang G, Zhang SY, Zhong S, Qi GL, Wang CJ, Chuai M, Lee KK, Lu DX, Yang X*. Exposing imidacloprid interferes with neurogenesis through impacting on chick neural tube cell survival. 153(1):137-48. Toxicol Sci. 2016. (IF: 3.88 ,共第一作者)
[14] Ma Z. L., Wang G., Lu W. H., Cheng X, Chuai M, Lee K K, Yang X*. Investigating the effect of excess caffeine exposure on placental angiogenesis using chicken “functional” placental blood vessel network. J Appl Toxicol. Feb;36(2):285-95. 2016(IF: 2.722, 共第一作者)
[15] Li S, Wang G, Gao L R, Lu W H, Wang X Y, Chuai M, K Lee K K, Cao L, Yang X *. Autophagy is involved in ethanol-induced cardia bifida during chick cardiogenesis. Cell Cycle. 14(20):3306-17. 2015. (IF:3.952,共第一作者)
[16] Han S, Wang G, Jin Y, Ma Z L, Jia W J, Wu X, Wang X Y , He M Y, Cheng X, Li W J, Yang X *, Liu G S*. Investigating the mechanism of hyperglycemia-induced fetal cardiac hypertrophy. PloS one. 10(9):e0139141. 2015. (IF: 3.057,共第一作者)
[17] Cheng X , Luo R , Wang G *, Xu C J, Feng X, Yang R H, Ding E, He Y Q, Chuai M, Lee K K, Yang X*. Effects of 2,5-hexanedione on angiogenesis and vasculogenesis in chick embryos. Reprod Toxicol. 2015, 51C:79-89. (IF: 2.85, 共第一作者&通訊作者)
[18] Jin Y. M., Wang G., Zhang N., Wei Y. F., Li S., Chen Y. P., Chuai M, Lee H. S., Hocher B., Yang X.*. Changes in the osmolarity of the embryonic microenvironment induces neural tube defects. Mol Reprod Dev. 82(5):365-76. 2015. (IF: 2.141,共第一作者)
[19] Lu W.H., Wang G., Li Y., Li S., Song X.Y., Wang X.Y., Chuai M., Lee K. K., Cao L.*, Yang X*. Autophagy functions on EMT in gastrulation of avian embryo. Cell Cycle. 13(17) :2752-2764. 2014 (IF: 4.565, 共第一作者)
[20] Ma Z. L., Wang G., Cheng X., Chuai M., Kurihara H., Lee K. K., Yang X*. Excess caffeine exposure impairs eye development during chick embryogenesis. J Cell Mol Med. 18 (6):1134-1143. 2014 (IF:4.014, 共第一作者)
[21] Chen Y., Wang G., Wang X. Y., Ma Z. L., Chen Y.P., Chuai M., Websky K., Hocher B. *, Yang X*. Effects of high salt-exposure on the development of retina and lens in 5.5-day chick embryo. Cell Physiol Biochem. 34(3):804-17. 2014 (IF:2.875, 共第一作者)
[22] Cheng X., Wang G., Ma Z. L., Chen Y. Y., Fan J. J., Zhang Z. L., Lee K. K., Luo H. M.*, Yang X*. Exposure to 2,5-hexanedione can induce neural malformations in chick embryos. Neurotoxicology 33 (5):1239-1247. 2012 (IF: 2.652, 共第一作者)
[23] Ma Z. L., Qin Y., Wang G., Li X. D., He R. R., Chuai M., Kurihara H. *, Yang X*. Exploring the caffeine-induced teratogenicity on neurodevelopment using early chick embryo. PloS one 7 (3):e34278. 2012 (IF: 3.73, 共第一作者)
[24] Cheng X. *, Wang G., Lee K. K., Yang X*. Dexamethasone use during pregnancy: potential adverse effects on embryonic skeletogenesis. Curr Pharm Des. 20(34):5430-7. 2014 (IF:3.452, 第二作者)
[25] Chen Y., Wang G., Ma Z. L., Li Y., Wang X. Y., Cheng X., Chuai M., Tang S. Z., Lee K. K., Yang X*. Adverse effects of high glucose levels on somite and limb development in avian embryos. Food Chem Toxicol 71C:1-9. 2014 (IF:2.895, 第二作者)
[26] Wang X Y, Li S, Wang G, Ma Z L, Chuai M L, Cao L, Yang X*. High glucose environment inhibits cranial neural crest survival by activating excessive autophagy in the chick embryo. Sci Rep. 5:18321. 2015 (IF:5.228, 第三作者)
[27] Gu Q., Wang C., Wang G., Han., Li Y., Wang X., Li j., Qi C., Xu T., Yang X.*, Wang L. J*. Glipizide suppresses embryonic vasculogenesis and angiogenesis through targeting natriuretic peptide receptor A. Exp Cell Res. 333(2):261-72. 2015. (IF:3.246,第三作者)
[28] Cheng Y S, Wang X Y,Wang G, LI Y, Chen Y L, Chuai M, Lee K K, Ding X Y*, Yang X*. Effects of anti-tumor drug sorafenib on chick embryo development. The Anatomical Record, 298(7):1271-81. 2015. (IF:1.542, 第三作者)
[29] Wang X. Y., Li Y., Wang G., Münsterberg A., Chuai M., Lee K. K., Wang L. J. *, Yang X*. Combinational electroporation and transplantation approach of studying gene functions in avian embryos. Chin Sci Bull. 59(7):616–624. 2014 (IF:1.579, 第三作者)
[30] Cheng X, Li H, Yan Y, Wang G, Berman Z, Chuai M, Yang X*. Usage of dexamethasone increases the risk of cranial neural crest dysplasia in the chick embryo. Toxicol Sci. Accepted. 2017 (IF: 3.854, 第四作者)
[31] Lu WH, Shi YX, Ma ZL, Wang G, Liu L, Chuai M, Song X, Münsterberg A, Cao L*, Yang X*. Proper autophagy is indispensable for angiogenesis during chick embryo development. Cell Cycle 15(13):1742-54. 2016. (IF:3.952,第四作者)
[32] Li P., Zhu W. J., Ma Z. L., Wang G., Peng H., Chen Y., Lee K. K., Yang X*. Enhanced beta-catenin expression and inflammation are associated with human ectopic tubal pregnancy. Human reproduction (Oxford, England) 28 (9):2363-2371. 2013 (IF: 4.585, 第四作者)
[33] Chen Y., Fan J. X., Zhang Z. L., Wang G., Cheng X., Chuai M., Lee K. K. *, Yang X*. The negative influence of high-glucose ambience on neurogenesis in developing quail embryos. PloS one 8 (6):e66646. 2013 (IF: 3.534, 第四作者)
[34] Hu X, Li J, Zhang Q, Zheng L,Wang G, Zhang X, Zhang J, Gu Q, Ye Y, Guo SW, Yang X*, Wang L*. Phosphoinositide 3-Kinase (PI3K) Subunit p110δ Is Essential for Trophoblast Cell Differentiation and Placental Development in Mouse. Sci Rep. Jun 16;6:28201. 2016. (IF:5.228, 第五作者)
[35] Cheng X, Yan Y, Chen J.L., Ma Z.L., Yang R.H., Wang G., Chuai M., Lee K.K., Yang X*. Dexamethasone exposure accelerates endochondral ossification of chick embryos via angiogenesis. Toxicol Sci. 2015. 149(1):167-77.(IF: 3.854, 第六作者)
[36] Yu Yan, Xin Cheng, Ren-hao Yang, He Li, Jian-long Chen, Zheng-lai Ma,Guang Wang, Manli Chuai, Xuesong Yang. Exposure to excess phenobarbital negatively influences the osteogenesis of chick embryos. Frontiers in Pharmacology. 2016 30;7:349. eCollection 2016.(IF: 4.418, 第七作者)
[37] Xiang Q., Hong D., Liao Y., Cao Y., Liu M., Pang J., Zhou J.,Wang G., Yang R., Wang M., Xiang A. P. Overexpression of Gremlin1 in Mesenchymal Stem Cells Improves Hindlimb Ischemia in Mice by Enhancing Cell Survival. J Cell Physiol. 2016 Aug 31. doi: 10.1002/jcp.25578.(IF: 4.155, 第八作者)
[38] Li W, Huang L, J Zeng, W Lin, K Li, J Sun, W Huang, J Chen,Wang G, Q Ke, J Duan, X Lai,R Chen, M Liu, Y Liu, T Wang, X Yang, Y Chen, H Xia and AP Xiang. Characterization and transplantation of enteric neural crest cells from human induced pluripotent stem cells. Molecular Psychiatry 2016. doi: 10.1038/mp.2016.191 (IF: 13.314, 第九作者)
[39] Li J., Ye Y., Zhang R., Zhang L., Hu X., Han D., Chen J., He X., Wang G., Yang X. *, Wang L. J*. Robo1/2 regulate follicle atresia through manipulating granulosa cell apoptosis in mice. Sci Rep. 5:9720. 2015. (IF:5.228, 第九作者)
