沈建忠(中國農業大學教授)

人物任職

學術任職

國家獸藥安全評價中心主任，國家獸藥殘留基準實驗室主任，農業部獸用化藥和中草藥創製與安全評價重點開放實驗室主任，農業部獸藥安全監督檢驗測試中心（北京）常務副主任。2015年當選為中國工程院院士，隸屬農學學部。

社會兼職

兼任中國畜牧獸醫學會獸醫藥理學與毒理學分會副理事長，中國畜牧獸醫學會藥品學分會副理事長，中國毒理學會飼料毒理學專業委員會副主任，國家農產品質量安全風險評估專家委員會委員，農業部第八屆科技委員會委員，中國獸藥典委員會委員，農業部獸藥殘留專家委員會委員，第五屆農業轉基因生物安全委員會委員。

研究領域

在獸醫藥理學與毒理學和動物性食品安全研究領域，

從事新獸藥創製、獸藥殘留檢測技術、動物及動物性食品中病原生物耐藥性產生與擴散及風險評估和獸藥環境生態毒理學等方面的研究教學工作。

主要成就

學術成就

主持完成和正在主持科研項目30餘項，包括十一五科技支撐計畫、十五國家科技攻關計畫、傑出青年科學基金項目、教育部新世紀優秀人才獎勵計畫、國家食品安全重大科技專項課題、國家自然科學基金項目、農業部殘留專項及國家農業行業標準制定項目等，研究經費超過4000萬元。

獲得獎勵

2009年獲得新中國60年畜牧獸醫科技貢獻獎（傑出人物） 2008年獲“首都教育體系奧運工作先進工作者”稱號 2006年度北京市教育創新標兵； 2006年獲國家科學技術進步二等獎； 2006年獲中國畜牧獸醫學會“感動中國畜牧獸醫科技創新領軍人物”稱號； 2005年獲北京市科學技術一等獎； 2005年獲北京市科學技術二等獎； 2005年獲全國優秀農業科技工作者稱號； 2004年獲寶鋼教育基金優秀教師獎； 2003年獲湖北省科技進步二等獎； 2001年獲北京市科技進步二等獎。

2018年11月，第六屆中華農業英才獎獲獎。

主要作品

論文

在AnalChem、JAgrFoodChem、FEMSMicrobiolLett、IntJAntimicrobAg、JClinMicrobiol、JAOACInt等國際學術刊物和中國農業科學、畜牧獸醫學報等國內學術刊物上發表論文150餘篇，其中SCI收錄論文95篇，EI收錄28篇，累計影響因子超過140，他引超過1000次HaiyangJiang,WeihongZhai,XiXia,ShuangyangDing,FeiXu,JianzhongShen*,XiaoweiLi,JinfengLiu.LCDeterminationofNosiheptideinSwineKidneyandLiver.Chromatographia.2010,71,131-134. 2. PengjieLuo,XiaChen,ChunlaiLiang,HuaKuang,LimingLu,ZhigangJiang,ZhanhuiWang,CunLi,SuxiaZhang,JianzhongShen.Simultaneousdeterminationofthiamphenicol,florfenicolandflorfenicolamineinswinemusclebyliquidchromatography–tandemmassspectrometrywithimmunoaffinitychromatographyclean-up.JournalofChromatographyB,2010,878(2),207-212 3. LimingLu,LeiDai,YangWang,CongmingWu,XiaChen,LinLi,YonghuaQi,LiningXia,JianzhongShen.CharacterizationofantimicrobialresistanceandintegronsamongEscherichiacoliisolatedfromanimalfarmsinEasternChina.ActaTropica,2010,113(1),20-25 4. XiXia,ShuangyangDing,XiaoweiLi,XiaoGong,SuxiaZhang,HaiyangJiang,JianchengLi,JianzhongShen.Validationofaconfirmatorymethodforthedeterminationofmelamineineggbygaschromatography–massspectrometryandultra-performanceliquidchromatography–tandemmassspectrometry.AnalyticaChimicaActa,2009,651(2),196-200 5. YonghuaQi,CongmingWu,SuxiaZhang,ZhanhuiWang,SiyangHuang,LeiDai,ShaochenWang,LiningXia,KaiWen,XingyuanCao,YongningWu,JianzhongShen*.SelectionofAnti-SulfadimidineSpecificScFvsfromaHybridomaCellbyEukaryoticRibosomeDisplay.2009.PLoSONE4(7):e6427.doi:10.1371/journal.pone.0006427. 6. JianzhongShen,XiXia,HaiyangJiang,CunLi,JianchengLi,XiaoweiLi,ShuangyangDing.Determinationofchloramphenicol,thiamphenicol,florfenicol,andflorfenicolamineinpoultryandporcinemuscleandliverbygaschromatography-negativechemicalionizationmassspectrometry.JournalofChromatographyB,2009,877(14-15),1523-1529 7. PengjieLuo,HaiyangJiang,ZhanhuiWang,CaimaoFeng,FangyangHe,JianzhongShen*.Simultaneousdeterminationofflorfenicolanditsmetaboliteflorfenicolamineinswinemuscletissuebyaheterologousenzyme-linkedimmunosorbentassay.JAOACInt,2009,92(3),981-988 8. PengjieLuo,XingyuanCao,ZhanhuiWang,HaiyangJiang,SuxiaZhang,XiaChen,JianpingWang,CaimaoFeng,JianzhongShen*.Developmentofanenzyme-linkedimmunosorbentassayforthedetectionofflorfenicolinfishfeed.FoodAgric.Immun.2009,20(1),57-65 9. WuCongming,WangYang,CaoXingyuan,LinJuchun,QinShangshang,MiTiejun,HuangSiyang,Shenjianzhong*.Emergenceofplasmid-mediatedquinoloneresistancegenesinEnterobacteriaceaeisolatedfromchickensinChina.JAntimicrobChemother.2009,63(2):408-411 10. WangYuping,LiLin,ShenJianzhong,YangFujiang,WuYongning*.Quinolone-resistanceinSalmonellaisassociatedwithdecreasedmRNAexpressionofvirulencegenesinvAandavrA,growthandintracellularinvasionandsurvival.VetMicrobiol.2009,133(4),328-334 11. HuaKuang,YongNingWu,XiaoLinHou,HongMiao,GongZhang,JianZhongShen,ChuanLaiXu.SynthesisofderivativesandproductionofantiserumforclassspecificdetectionofpyrethroidsbyindirectELISA.InternationalJournalofEnvironmentalAnalyticalChemistry,2009,89(6),423-437 12. ShenJianzhong,XiaXi,JiangHaiyang,LiCun,LiJiancheng,LiXiaowei,DingShuangyang*.Determinationofchloramphenicol,thiamphenicol,florfenicol,andflorfenicolamineinpoultryandporcinemuscleandliverbygaschromatography-negativechemicalionizationmassspectrometry.JChromatogrBAnalytTechnolBiomedLifeSci.2009,877(14-15):1523-1529. 13. 程林麗，張素霞，沈建忠*，王戰輝，李彥伸，馮培生.高效液相色譜法快速檢測豬組織中泰妙菌素殘留.2009.分析化學.37(5)，718-720 14. 劉勇軍，吳銀良，姜艷彬，沈建忠*.高效液相色譜-串聯質譜法測定豬肉中泰拉黴素殘留.分析化學.2009，10，1489-1493 15. 李存，江海洋，吳銀良，王戰輝，趙思俊，李建成，石玉祥，沈建忠*.高效液相色譜-螢光-紫外法測定動物肌肉組織中多類藥物殘留.分析化學.2009，8，1102-1106 16. 趙思俊，鄭增忍，曲志娜，江海洋，張素霞，沈建忠*.免疫親和色譜-HPLC-FLD法測定動物肝臟中10種喹諾酮類藥物殘留.2009.分析化學.37(3)，335-340 17. XiaXi,LiXiaowei,DingShuangyang,ZhangSuxia,JiangHaiyang,LiJiancheng,ShenJianzhong*.Ultra-high-pressureliquidchromatography-tandemmassspectrometryfortheanalysisofsixresorcylicacidlactonesinbovinemilk.JChromatogrA.2009,1216(12):2587-2591. 18. ZhaoSijun,LiXuelian,RaYounkyoung,LiCun,JiangHaiyang,LiJiancheng,QuZhina,ZhangSuxia,HeFangyang,WanYuping,FengCaiwei,ZhengZengren,ShenJianzhong*.Developingandoptimizinganimmunoaffinitycleanuptechniquefordeterminationofquinolonesfromchickenmuscle.JAgricFoodChem.2009,57(2):365-371. 19. XiaXi,LiXiaowei,DingShuangyang,ZhangSuxia,JiangHaiyang,LiJiancheng,ShenJianzhong*.Determinationof5-nitroimidazolesandcorrespondinghydroxymetabolitesinswinekidneybyultra-performanceliquidchromatographycoupledtoelectrospraytandemmassspectrometry.AnalChimActa.2009,637(1-2):79-86. 20. LiXiubo,WuWenxue*,SuDan,WangZhijian,JiangHaiyang,ShenJianzhong.Pharmacokineticsandbioavailabilityofcefquinomeinhealthypiglets.2008.JVetPharmacolTherap.31,523-527 21. 王戰輝，丁雙陽，張素霞，沈建忠.分子模擬技術研究17種磺胺類藥物與抗體親和力構效關係.化學學報.2008.66(23)，2613-2619 22. ShenJianzhong,LiHaiyan,JiangHaiyang,ZhouDegang,XuFei,LiJiancheng,DingShuangyang*.Simultaneousdeterminationof13quinolonesineggsusingcolumnhigh-performanceliquidchromatography/electrosprayionization-tandemmassspectrometryanddepletionofpefloxacinmethanesulfonateineggs.JAOACInt.2008,91(6):1499-1506. 23. LiBingyu,LiCun,JiangHaiyang,WangZhanhui,CaoXingyuan,ZhaoSijun,ZhangSuxia,ShenJianzhong*.Purificationofninesulfonamidesfromchickentissuesbyimmunoaffinitychromatographyusingtwomonoclonalantibodies.JAOACInt.2008,91(6):1488-1493. 24. YounkyoungRa,CunLi,HaiyangJiang,SuxiaZhang,SijunZhao,XiaoweiLi,JianzhongShen*.Immunoaffinitychromatographyclean-upandLCforanalysisofsalinomycinandnarasininchickenmuscle.Chromatographia.2008,69,701-706. 25. ZhangSuxia,LiuZhongwei,GuoXia,ChengLinli,WangZhanhui,ShenJianzhong*.Simultaneousdeterminationandconfirmationofchloramphenicol,thiamphenicol,florfenicolandflorfenicolamineinchickenmusclebyliquidchromatography-tandemmassspectrometry.JChromatogrBAnalytTechnolBiomedLifeSci.2008,875(2):399-404. 26. CunLi,ZhanhuiWang,XingyuanCao,BCBeier,SuxiaZhang,ShuangyangDing,XiaoweiLi,JianzhongShen*Developmentofanimmunoaffinitycolumnmethodusingbroad-specificitymonoclonalantibodiesforsimultaneousextractionandcleanupofquinoloneandsulfonamideantibioticsinanimalmuscletissues.JChromatogrA,2008,1209(1-2),1-9. 27. XiXia,XiaoweiLi,SuxiaZhang,ShuangyangDing,HaiyangJiang,JianchengLi,JianzhongShen∗.Simultaneousdeterminationof5-nitroimidazolesandnitrofuransinporkbyhigh-performanceliquidchromatography–tandemmassspectrometry.JChromatogrA.2008,1208(1-2):101-108 28. LeiDai,LimingLu,CongmingWu,BeibeiLi,SiyangHuang,ShaochenWang,YonghuaQi,JianzhongShen*.CharacterizationofantimicrobialresistanceamongEscherichiacoliisolatesfromchickensinChinabetween2001and2006.2008.FEMSMicrobiolLett.286,178-183 29. YanZhu,LinLi,ZhanhuiWang,YiqiangChen,ZhengmiaoZhao,LiangZhu,XiaopingWu,YupingWan,FangyangHe,JianzhongShen*.Developmentofanimmunochromatographystripfortherapiddetectionof12fluoroquinolonesinchickenmuscleandliver.2008.JAgrFoodChem.56,5469–5474 30. HaiyangJiang,DegangZhou,HaiyanLi,FeiXu,CunLi,JianzhongShen,XiaoweiLi,ShuanyangDing*.LC-fluorescencedetectionofabamectin,ivermectin,doramectin,andeprinomectininrabbitfeces.2008.Chromatographia.68,259-262 31. CunLi,HaiyangJiang,SijunZhao,SuxiaZhang,ShuangyangDing,JianchengLi,XiaoweiLi,JianzhongShen*.SimultaneousdeterminationoffluoroquinolonesandsulfonamidesinchickenmusclebylcwithfluorescenceandUVdetection.2008.Chromatographia.68,117-121 32. 王戰輝，張素霞，沈建忠*.螢光偏振免疫分析測定磺胺甲基嘧啶研究.光譜學與光譜分析.2008.28（7），1621-1625 33. 吳銀良，李存，劉勇軍，姜艷彬，劉興國，沈建忠*.高效液相色譜法快速測定鴨肉和鴨蛋中蘇丹紅染料.2008.分析化學.3，843-845 34. 王戰輝，張素霞，丁雙陽，沈建忠*.螢光偏振免疫分析法研究17種磺胺類藥物與抗體親和力的構效關係.2008.高等學校化學學報.29（6），1107-1111 35. WangYang,WuCongming,LuLiming,NaRenGaowa,CaoXingyuan,ShenJianzhong*.Macrolide–lincosamide-resistantphenotypesandgenotypesofStaphylococcusaureusisolatedfrombovineclinicalmastitis.2008.VetMicrobiol.130(1-2),118-125 36. WangGuiqin,WuCongming,DuXiangdang,ShenZhangqi,SongLihong,ChenXia,ShenJianzhong*.Characterizationofintegrons-mediatedantimicrobialresistanceamongEscherichiacolistrainsisolatedfrombovinemastitis.2008.VetMicrobiol.127,73-78 37. ZhangSuxia,LiuZongwei,ZhouNaiyuan,WangZhanhui,ShenJianzhong*.Aliposomeimmunelysisassayforenrofloxacinincarpandchickenmuscle.2008.AnalChimActa.612,83-88 38. ZhanhuiWang,SuxiaZhang,NailyaR.Murtazina,SergeiA.Eremin,JianzhongShen*.Determinationoftheveterinarydrugmaduramicininfoodbyfluorescencepolarisationimmunoassay.2008.InternationalJFoodSciTech,43(1),114-122 39. ZhanhuiWang,SuxiaZhang,ShuangyangDing,SergeiA.Eremin,JianzhongShen*.Simultaneousdeterminationofsulphamerazine,sulphamethazineandsulphadiazineinhoneyandchickenmusclebyanewmonoclonalantibody-basedfluorescencepolarisationimmunoassay.2008.FoodAdditContam,25(5),574-582 40. 王戰輝，張素霞，沈建忠*，SergeiAEremin.螢光偏振免疫分析在農藥和獸藥殘留檢測中的研究進展.2007.光譜學與光譜分析.27（11），2299-2306 41. Zhang,Xiaoguang;Li,Jiancheng;Jiang,Haiyang;Shen,Jianzhong*.Residuedepletionofcefquinomeinswinetissuesafterintramuscularadministration.2007.JAgrFoodChem.55(25),10493-10498. 42. JianzhongShen,FeiXu,HaiyangJiang,ZhanhuiWang,JingTong,PengjuGuo,ShuangyangDing*.Characterizationandapplicationofquantumdotnanocrystal–monoclonalantibodyconjugatesforthedeterminationofsulfamethazineinmilkbyfluoroimmunoassay.2007.AnalBioanalChem.389,2243-2250 43. HaiyangJiang,ShuangyangDing,FeiXu,SijunZhao,JihongHe,JinfengLiu,XiaolinHou,JianzhongShen*.DeterminationofeprinomectininbovineurineandfecesusingHPLCwithfluorescencedetection.2007.Chromatographia.66,411-414 44. WuYinliang*,LiCun,LiuYongjun,ShenJianzhong*.ValidationmethodforthedeterminationofsulfonamideresiduesinbovinemilkbyHPLC.2007.Chromatographia.66(3-4),191-195 45. 趙思俊，李存，江海洋，李炳玉，沈建忠*.高效液相色譜檢測動物肌肉組織中7種喹諾酮類藥物的殘留.2007.分析化學.35(6)，786-790 46. 王戰輝，張素霞，沈建忠*.螢光偏振免疫分析方法分析磺胺二甲基嘧啶.2007.分析化學.35(6)，819-824 47. ZhanhuiWang,SuxiaZhang,IrinaS.Nesterenko,SergeiA.Eremin,JianzhongShen*.Monoclonalantibody-basedfluorescencepolarizationimmunoassayforsulfamethoxypyridazineandsulfachloropyridazine.2007.JAgrFoodChem.55,6871-6878 48. SuxiaZhang,ZhanhuiWang,IrinaS.Nesterenko,SergeiA.Eremin,JianzhongShen*.Fluorescencepolarisationimmunoassaybasedonamonoclonalantibodyforthedetectionofsulphamethazineinchickenmuscle.2007.IntJFoodSciTech.42,36–44 49. WangZhanhui,ZhuYan,DingShuangyang,HeFangyang,BeierRC,LiJiancheng,JiangHaiyang,FengCaiwei,WanYuping,ZhangSuxia,KaiZenpeng,YangXinling,ShenJianzhong*.Developmentofamonoclonalantibody-basedbroad-specificityelisaforfluoroquinoloneantibioticsinfoodsandmolecularmodelingstudiesofcross-reactivecompounds.2007.AnalChem.79(12),4471-4483 50. ZhiyiQiang,FenqinShentu,BingWang,JianpingWang,JianyuChang,andJianzhongShen*.Residuedepletionofractopamineanditsmetabolitesinswinetissues,urine,andserum.2007.JAgrFoodChem.55(11),4319-4326 51. ZhaoSijun,JiangHaiyang,LiXuelian,MiTiejun,LiCun,ShenJianzhong*.Simultaneousdeterminationoftracelevelsof10quinolonesinswine,chicken,andshrimpmuscletissuesusingHPLCwithprogrammablefluorescencedetection.2007.JAgrFoodChem.55(10),3829-3834. 52. ZhaoSijun,JiangHaiyang,DingShuangyang,LiXuelian,WangGuiqin,LiCunandShenJianzhong*.Areliablelcmethodwithfluorescencedetectionforquantificationof(fluoro)quinoloneresiduesinchickenmuscle.2007.Chromatographia.65,539-544. 53. XiaolinHou,YongningWu,JianzhongShen*,LeiWang,ShuangyangDing.Multi-residueanalysisofavermectinsinbovineliverandmusclebyliquidchromatography–fluorescencedetector.2007,Chromatographia.65,77-80 54. ZhouJinhui,ShenJianzhong,XuoXiaofeng,ZhaoJing,LiYi,ZhangJinzhen,ZhangSuxia*.Simultaneousdeterminationofnitroimidazoleresiduesinhoneysamplesbyhigh-performanceliquidchromatographywithultravioletdetection.2007.JAOACInt.90(3),872-878 55. JianzhongShen,ZhenZhang,YanYao,WeiminShi,YibingLiu,SuxiaZhang*.Time-resolvedfluoroimmunoassayforractopamineinswinetissue.2007,AnalBioanalChem.387(4),1561-1564 56. XiaXi,LiXiaowei,ZhangSuxia,DingShuangyang,JiangHaiyang.ShenJianzhong*.Confirmationoffournitroimidazolesinporcineliverbyliquidchromatography-tandemmassspectrometry.2007.AnalChimActa.586,394-398 57. JianchengLi,ShuangyangDing,SuxiaZhang,CunLi,XiaoweiLi,ZhongweiLiu,JinfengLiu,JianzhongShen*.Residuedepletionofflorfenicolanditsmetaboliteflorfenicolamineinswinetissuesafterintramuscularadministration.2006.JAgrFoodChem.54,9614-9619 58. ZhuoWang,XunSuo,XiXia,andJianzhongShen*.InfluenceofmonensinoncationinfluxandNa+-K+-atpaseactivityofeimeriatenellasporozoitesinvitro.2006.JParasitol.92(5),1092-1096 59. WeiZhang,HejiaWang,JianpingWang,XiaoweiLi,HaiyangJiang,JianzhongShen*.MultiresiduedeterminationofzeranolandrelatedcompoundsinbovinemusclebyGC/MSwithimmunoaffinitycleanup.2006.JAOACInt.89(6),1677-1681 60. WangJianping,LiXiaowei,ZhangWei,ShenJianzhong*.Developmentofimmunoaffinitysample-purificationforgc–msanalysisofractopamineinswinetissue.2006.Chromatographia.64,613-617 61. 吳銀良，劉素英，劉勇軍，沈建忠*，王海，單吉浩.固相萃取-氣相色譜-質譜法測定豬組織中沙丁胺醇殘留量.分析化學.2006，34，23-26 62. SuxiaZhang,FengyunSun,JianchengLi,LinliCheng,andJianzhongShen*.Simultaneousdeterminationofflorfenicolandflorfenicolamineinfish,shrimpandswinemusclebygaschromatographywithamicrocellelectroncapturedetector.2006.JAOACInt.89(5),1437-1441 63. 吳銀良，李曉薇，劉素英，沈建忠*，楊挺.氣相色譜-質譜法測定肝臟組織中鹽酸克倫特羅和鹽酸萊克多巴胺.2006.分析化學.34（8），1083-1086 64. JianzhongShen,ZhenZhang,YanYao,WeiminShi,YibingLiuandSuxiaZhang*.Amonoclonalantibody-basedtime-resolvedfluoroimmunoassayforchloramphenicolinshrimpandchickenmuscle.2006.AnalChimActa.575(2),262-266 65. WeiminShi,JihongHe,HaiyangJiang,XiaolinHou,JunhongYang,JianzhongShen*.DeterminationofmultiresidueofavermectinsinbovineliverbyanindirectcompetitiveELISA.2006.JAgrFoodChem.54(17),6143-6146 66. ShuangyangDing,JunxiaChen,HaiyangJiang,JihongHe,WeiminShi,WenshenZhao,andJianzhongShen*.Theapplicationofquantumdot-antibodyconjugatesfordetectionofsulfamethazineresidueinchickenmuscletissue.2006.JAgrFoodChem.54(17),6139-6142 67. SuxiaZhang,ZhenZhang,WeiminShi,SergeiA.Eremin,andJianzhongShen*.Developmentofchemiluminescentelisafordeterminingchloramphenicolinchickenmuscle.2006.JAgrFoodChem.54(16),5718-5722 68. XiaXi,LiXiaowei,ShenJianzhong*,ZhangSuxia,DingShuangyang,JiangHaiyang.Determinationofnitroimidazoleresiduesinporcineurineusingliquidchromatography-tandemmassspectrometry.2006.JAOACInt.89(4),1116-1119 69. HouXiaolin,JiangHaiyang,DingShuangyang,ZhangSuxia,LiXiaowei,ShenJianzhong*.Multi-residueanalysisofavermectinsincattleliverbyliquidchromatography-tandemmassspectrometry.2006.JAOACInt.89(4),1110-1115 70. HaiyangJiang,ShuangyangDing,JianchengLi,DianjinAn,CunLi,JianzhongShen*.Residuedepletionoftilmicosinincattleaftersubcutaneousadministration.2006.JAgrFoodChem.54(14),5208-5213 71. XiaolinHou,XiaoweiLi,ShuangyangDing,JihongHe,HaiyangJiangandJianzhongShen*.Simultaneousanalysisofavermectinsinbovinetissuesbylc-ms-mswithimmunoaffinitychromatographycleanup.2006.Chromatographia.63,543-550 72. ZhuoWang,JianzhongShen*,XunSuo,ShiyunZhao,XingyuanCao.Experimentallyinducedmonensin-resistantEimeriatenellaandmembranefluidityofsporozoites.2006.VetParasitol.138,186-193 73. WangJianping,ZhangSuxia,ShenJianzhong*.Amonoclonalantibodybased-immunoassayfordeterminationofractopamineinswinefeeds.2006.JAnimSci.84,1248-1251 74. XingyuanCao,MeiDong,JianzhongShen*,BeibeiWu,CongmingWu,XiangdangDu,ZhuoWang,YitaoQi,BingyuLi.Tilmicosinandtylosinhaveanti-inflammatorypropertiesviamodulationofCOX-2andiNOSgeneexpressionandproductionofcytokinesinLPS-inducedmacrophageandmonocytes.2006.IntJAntimicrobAg.27(5),431-438 75. 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沈建忠(中國農業大學教授)

基本介紹