梁曉暉:女,武漢大學公共衛生學院副教授
湖南醫科大學醫療系學士,新加坡國立大學博士,美國約翰霍普金斯醫學院腫瘤科博士後。曾在中南大學湘雅醫院感染科,清華大學醫院內科和武漢大學人民醫院任臨床醫生,2012年進入公共衛生學院。科研方面曾以第一作者發表SCI論文5篇,通訊作者2篇,參與作者發表SCI文章4篇。教學方面,參與的教學課程包括:衛生學,勞動衛生學,衛生法律法規與監督學,醫學文獻檢索,環境污染與人類健康,全球健康概論和專業英文。
主要研究課題:
1,全球健康信息平台構建
2. 兒童鉛中毒的臨床調查
3. 食品藥品安全
4. 環境與腫瘤
代表性論著
1. Liang XiaoHui, Heng Chew Kiat, Cheung Wai, Wang De Yun. Absent of the toll-like receptor 4 gene polymorphisms Asp200G1y and Thr399I1e in Singaporean Chinese. Therapeutics and clinical risk management, 2005: 1(3): 243-46。
2. Liang XiaoHui, Cheung Wai, Heng Chew Kiat, Wang De Yun. Reduced transcriptional activity in individuals with interleukin-18 gene variants detected from functional but not association study. Biochemical and Biophysical Research Communication, 2005: 338: 736-41
3. Liang XiaoHui, Heng Chew Kiat, Cheung Wai, Liu Jian Jun, Li Chun Wei, Lim Bing, Wang De Yun. CD14 promoter polymorphisms have no functional significance and are not associated with atopic phenotypes. Pharmacogenetics and Genomics, 2006: 16: 229-36
4. Liang XH, Lau QC, Salto-Tellez M, Putti TC, Loh M, Sukumar S. Mutational hotspot in exon 20 of PIK3CA in breast cancer among Singapore Chinese. Cancer Biol Ther. 2006: 5 (5): 544-8
5. Chen H, Zhang H, Lee J, Liang X, Wu X, Zhu T, Lo PK, Zhang X, Sukumar S. HOXA5 acts directly downstream of retinoic acid receptor beta and contributes to retinoic acid-induced apoptosis and growth inhibition. Cancer Res. 2007 Sep 1;67(17):8007-13.
6. Liang XiaoHui, Cheung Wai, Wang De Yun. Differential and opposed transcriptional effects of IL-18 gene polymorphisms (-137, +113 and +127) in human HepG2, Hela, U937 and THP-1 cells. Med Sci Monit, 2008; 14(1): BR8-13.
7. Chen H, Lee JS, Liang X, Zhang H, Zhu T, Zhang Z, Taylor ME, Zahnow C, Feigenbaum L, Rein A, Sukumar S. Hoxb7 inhibits transgenic HER-2/neu-induced mouse mammary tumor onset but promotes progression and lung metastasis. Cancer Res. 2008 May 15;68(10):3637-44. Epub 2008 May 7。
8. Lo PK, Watanabe H, Cheng PC, Teo WW, Liang X, Argani P, Lee JS, Sukumar S. J Mol Diagn. MethySYBR, a novel quantitative PCR assay for the dual analysis of DNA methylation and CpG methylation density. 2009 Sep;11(5):400-14.
9. Lo PK, Lee JS, Liang X, Han L, Mori T, Fackler MJ, Sadik H, Argani P, Pandita TK, Sukumar S. Epigenetic inactivation of the potential tumor suppressor gene FOXF1 in breast cancer.Cancer Res. 2010 Jul 15;70(14):6047-58. Epub 2010 Jun 29.
10.Li Y, Wu S, Xiang Y, Liang X.An investigation of outpatient children's blood lead level in Wuhan China. PLoS One. 2014 Apr 16; 9(4): e95284.(Corresponding author)
11. Shao J, Li Y, Zhao P, Yue X, Jiang J, Liang X, He X. Association of mTOR polymorphisms with cancer risk and clinical outcomes: a meta-analysis. LoS One. 2014 May 9;9(5):e97085.(Co-Corresponding author)。