李富花

李富花

李富花，女，1965年11月出生，中國科學院海洋研究所實驗海洋生物學重點實驗室研究員，博士生導師。研究方向：甲殼動物繁殖與遺傳。 長期從事海洋動物特別是甲殼動物的繁殖和遺傳研究。作為課題負責人主持瑞典國際基金項目2項，國家自然科學基金面上項目5項，國際合作重點項目1項，國家973項目課題1項，國家863計畫項目4項。現為農業部蝦產業技術體系崗位專家，任蝦產業技術體系病害控制功能實驗室主任。在對蝦的繁殖發育、遺傳育種和功能基因組學研究方面取得了一系列成果，已在國內外學術刊物發表論文100餘篇，其中SCI收錄論文80餘篇。獲國際發明專利授權1項，申請或獲得國家發明專利10餘項；獲山東省自然科學二等獎2項，國家海洋局科技創新成果二等獎2項

基本介紹

  • 中文名：李富花
  • 出生日期：1965年11月
  • 性別：女
  • 研究方向：甲殼動物繁殖與遺傳
人物經歷,教育經歷,工作簡歷,發表文章,

人物經歷

1987年畢業於廈門大學生物系獲學士學位，1990年獲廈門大學海洋系海洋生物學專業碩士學位，1999年獲中國科學院海洋研究所海洋生物學專業博士學位。自1990年起在中科院海洋研究所工作，期間，作為訪問學者，曾赴美國、法國、澳大利亞等國進行合作研究：美國康州大學細胞及分子生物學系訪問學者（1998.1-1999.5），法國IFREMER和蒙彼利埃第二大學高級訪問學者（2005.1-2005.4），澳大利亞聯邦科學和工業組織（CSIRO）動物研究所高級訪問學者（2009.2-2009.3）。

教育經歷

1983年9月—1987年7月：廈門大學生物系動物學專業學習，獲學士學位
1987年9月—1990年10月：廈門大學海洋系海洋生物專業學習，獲碩士學位
1993年9月—1999年7月：中科院海洋研究所在職博士生，獲博士學位

工作簡歷

1990年10月—1993年2月：中科院海洋研究所，研究實習員；
1993年2月—1996年2月：中科院海洋所，助理研究員；
1996年2月—2001年10月: 中科院海洋所，副研究員；
2001年10月-至今：中科院海洋研究所研究員；
1998年1月—1999年5月：美國康州大學細胞及分子生物學系，訪問學者。
2005年1月-2005年4月：法國蒙彼利埃第二大學，高級訪問學者
2009年2月-2009年3月: 澳大利亞聯邦科學與工業組織（CSIRO）動物研究所，高級訪問學者。

發表文章

在國內外學術刊物發表論文100餘篇，其中SCI收錄論文80餘篇
近五年發表的主要SCI收錄論文（*代表通訊作者）：
  1. Shihao Li, Shuyue Guo, Fuhua Li*, Jianhai Xiang, 2014. Characterization and function analysis of an anti-lipopolysaccharide factor (ALF) from the Chinese shrimp Fenneropenaeus chinensis. Developmental and Comparative Immunology 46: 349-355.
  2. Yumiao Sun,Fuhua Li*, Zheng Sun , Xiaojun Zhang, Shihao Li, Chengsong Zhang, Jianhai Xiang, 2014. Transcriptome analysis of the initial stage of acute WSSV infection caused by temperature change. PLoS ONE 9(3): e90732.
  3. Shuyue Guo, Shihao Li, Fuhua Li*, Xiaojun Zhang, Jianhai Xiang, 2014. Modification of a synthetic LPS-binding domain of anti-lipopolysaccharide factor from shrimp reveals strong structure-activity relationship in their antimicrobial characteristics. Developmental and Comparative Immunology. 45, 227-232.
  4. Rong Wen, Fuhua Li*, Shihao Li, Jianhai Xiang, 2014. Function of Shrimp STAT during WSSV Infection. Fish& Shellfish Immunology 38: 354-260.
  5. Rong Wen, Fuhua Li*, Yusu Xie, Shihao Li, Chengsong Zhang, Kuijie Yu & Jianhai Xiang (2014): Cloning and expression analysis on a homolog of spermatogonial stem-cell renewal factor in Fenneropenaeus chinensis. Invertebrate Reproduction & Development, DOI: 10.1080/07924259.2014.905501
  6. Jingwen Liu, Yang Yu, Fuhua Li*, Xiaojun Zhang, Jianhai Xiang, 2014. A new anti-lipopolysaccharide factor (ALF) gene with its SNP polymorphisms related to WSSV resistance of L. vannamei. Fish and shellfish immunology, 39:24-33.
  7. Zheng Sun, Shihao Li, Fuhua Li*, Junbin Zhang, Jianhai Xiang, 2014. Prediction on the invasion route of WSSV infection to shrimp by bioinformatics analysis. BioMed Research International, Volume 2014, Article ID 416543, 9 pages.
  8. Yang Yu, Jiankai Wei, Xiaojun Zhang, Jingwen Liu, Chengzhang Liu, Fuhua Li*, Jianhai Xiang, 2014. SNP discovery in the transcriptome of White Pacific Shrimp Litopenaeus vannamei by next generation sequencing. PLoS ONE 9(1): e87218..
  9. Ningning Feng, Dongdong Wang, Rong Wen, Fuhua Li*, 2014. Functional analysis on immune deficiency (IMD) homolog gene in Chinese shrimp Fenneropenaeus chinensis. Molecular Biology Reports, 41(3): 1437-1444.
  10. Hao Jiang, Fuhua Li, Jiquan Zhang, Jinkang Zhang, Bingxin Huang, Yang Yu, Jianhai Xiang, 2014. Comparison of protein expression profiles of the hepatopancreas in Fenneropenaeus chinensis with heat-inactivated Vibrio anguillarum and white spot syndrome virus. Marine Biotechnology 16(1)：111-123.
  11. Chengsong Zhang,Fuhua Li, Jianhai Xiang, 2014. Effect of starvation on survival, growth, and development of Exopalaemon carinicauda larvae, Aquaculture Research，2014: 1-11.
  12. Chengsong Zhang, Fuhua Li, Jianhai Xiang, 2014. Acute effects of cadmium and copper on survival, oxygen consumption, ammonia-N excretion, and metal accumulation in juvenile Exopalaemon carinicauda, Ecotoxicology and Environmental Safety, Ecotoxicology and Environmental Safety 104:209-214.
  13. Fuhua Li, Jianhai Xiang, 2013. Recent advances in researches on the innate immunity of shrimp in China. Developmental and Comparative Immunology 39: 11-26.
  14. Fuhua Li, Jianhai Xiang, 2013. Signaling pathways regulating innate immune responses in shrimp. Fish and Shellfish Immunology 34:973-980.
  15. Yumiao Sun,Fuhua Li*, Jianhai Xiang, 2013. Analysis on the dynamic changes of the amount of WSSV in Chinese shrimp Fenneropenaeus chinensis. Aquaculture 376-379: 124-132.
  16. Rong Wen,Fuhua Li*, Zheng Sun, Shihao Li, Jianhai Xiang, 2013. Shrimp MyD88 Responsive to Bacteria and White Spot Syndrome Virus. Fish & Shellfish Immunology 34(2):574-581.
  17. Dongdong Wang, Fuhua Li*, Shihao Li, Yanhong Chi, Rong Wen, Ningning Feng, Jianhai Xiang, 2013. An IκB homologue (FcCactus) in Chinese shrimp Fenneropenaeus chinensis. Developmental and Comparative Immunology 39(4):352-362.
  18. Shihao Li, Xiaojun Zhang, Zheng Sun, Fuhua Li*, Jianhai Xiang, 2013. Transcriptome analysis on Chinese shrimp Fenneropenaeus chinensis during WSSV acute infection. PLoS ONE 8(3): e58627.
  19. Dongdong Wang, Shihao Li, Fuhua Li*, 2013. Screening of genes regulated by Relish in Chinese shrimp Fenneropenaeus chinensis. Developmental and Comparative Immunology 41, 209-216.
  20. Yanhong Chi, Fuhua Li*, Yumiao Sun, Rong Wen, Shihao Li, 2013. Expression and function analysis of Rac1 homolog in Chinese shrimp Fenneropenaeus chinensis. Fish & Shellfish Immunology 35(3): 927-932.
  21. Hao Jiang, Fuhua Li, Jiquan Zhang, Jinkang Zhang, Bingxin Huang, Yang Yu, Jianhai Xiang, 2013. Comparison of protein expression profiles of the hepatopancreas in Fenneropenaeus chinensis with heat-inactivated Vibrio anguillarum and white spot syndrome virus. Marine Biotechnology. DOI 10.1007/s10126-013-9538-8.
  22. Liyan Wang, Fuhua Li, Bing Wang, Jianhai Xiang, 2013. A new shrimp peritrophin-like gene from Exopalaemon carinicauda involved in white spot syndrome virus (WSSV) infection. Fish & Shellfish Immunology 35(3): 840-846.
  23. Rong Wen, Fuhua Li*, Yusu Xie, Shihao Li, Jianhai Xiang, 2012. A Homolog of Cell Apoptosis Susceptibility Gene Involved in the Ovary Development of Chinese Shrimp Fenneropenaeus chinensis. Biology of Reproduction 86(1):1-7.
  24. Dongdong Wang, Fuhua Li*, Shihao Li, Rong Wen, Jianhai Xiang, 2012. Expression profiles of antimicrobial peptides (AMPs) and their regulation by Relish. Chinese Journal of Oceanology and Limnology, 30 ( 4): 611-619.
  25. Dongdong Wang, Fuhua Li*, Yanhong Chi, Jianhai Xiang, 2012. Functional relationship among the major antioxidant enzymes in eliminating hydrogen peroxide in penaeid shrimp. Cell Stress and Chaperone, 17(4): 423-433.
  26. Shihao Li, Fuhua Li*, Zheng Sun, Jianhai Xiang,2012. Two spliced variants of insulin-like androgenic gland hormone gene in the Chinese shrimp, Fenneropenaeus chinensis. General and Comparative Endocrinology 177(2012): 246-255.
  27. Shihao Li, Fuhua Li*, Rong Wen, Jianhai Xiang, 2012. Identification and characterization of the sex-determiner transformer-2 homologue in Chinese shrimp, Fenneropenaeus chinensis. Sexual Development 6: 267–278.
  28. Liyan Wang, Fuhua Li, Bing Wang, Jianhai Xiang, 2012. Structure and partial protein profiles of the peritrophic membrane (PM) from the gut of the shrimp Litopenaeus vannamei. Fish & Shellfish Immunology 33(6): 1285-1291.
  29. M.J. Sellars, Fuhua Li, N.P. Preston, J. Xiang, 2010. Penaeid shrimp polyploidy: Global status and future direction. Aquaculture 310:1-7.
  30. Fuhua Li, Dongdong Wang, Shihao Li, Hui Yan, Jinkang Zhang, Bing Wang, Jiquan Zhang, Jianhai Xianga, 2010. A Dorsal homolog (FcDorsal) in the Chinese shrimp Fenneropenaeus chinensis is responsive to both bacteria and WSSV challenge. Developmental and Comparative Immunology 34,874–883.
  31. Shihao Li, Fuhua Li*, Bing Wang, Yusu Xie, Rong Wen, Jianhai Xiang, 2010. Cloning and expression profiles of two isoforms of a CHH-like gene specifically expressed in male Chinese shrimp, Fenneropenaeus chinensis. General and Comparative Endocrinology 167, 308-316.
  32. Jinkang Zhang, Fuhua Li* , Hao Jiang, Yang Yu, Chengzhang Liu, Shihao Li, Bing Wang, Jianhai Xiang , 2010. Proteomic analysis of differentially expressed proteins in lymphoid organ of Fenneropenaeus chinensis response to Vibrio anguillarum stimulation. Fish & Shellfish Immunology 29, 186-194.
  33. Yusu Xie, Fuhua Li*, Bing Wang, Shihao Li, Dongdong Wang, Hao Jiang, Chengsong Zhang, Kuijie Yu, Jianhai Xiang, 2010. Screening of genes related to ovary development in Chinese shrimp Fenneropenaeus chinensis by suppression subtractive hybridization. Comparative Biochemistry and Physiology, Part D 5 (2010) 98–104
  34. Wei Luan, Fuhua Li*, Jiquan Zhang, Rong Wen, Yutao Li and Jianhai Xiang, 2010. Identification of a novel inducible cytosolic Hsp70 gene in Chinese shrimp Fenneropenaeus chinensis and comparison of its expression with the cognate Hsc70 under different stresses. Cell Stress & Chaperone 15: 83-93.
  35. Fuhua Li*, Hui Yan, Dongdong Wang, T.A. Jose Priya, Shihao Li, Bing Wang, Jiquan Zhang, Jianhai Xiang，2009. Identification of a novel relish homolog in Chinese shrimp Fenneropenaeus chinensis and its function in regulating the transcription of antimicrobial peptides. Developmental and Comparative Immunology 33, 1093-1101.
  36. Fuhua Li*, Wei Luan, Chengsong Zhang et al., 2009. Cloning of cytoplasmic heat shock protein 90 (FcHSP90) from Fenneropenaeus chinensis and its expression response to heat shock and hypoxia. Cell Stress Chaperones 14，161-172。
  37. Hao Jiang, Fuhua Li, Yusu Xie, Bingxin Huang, Jinkang Zhang, Jiquan Zhang, Chengsong Zhang, Shihao Li, Jianhai Xiang, 2009. Comparative proteomic profiles of the hepatopancreas in Fenneropenaeus chinensis response to hypoxic stress. Proteomics. Proteomics 9, 3353–3367.
  38. Yichen Liu, Fuhua Li, Bing Wang, Bo Dong, Xiaojun Zhang, Jianhai Xiang, 2009. A serpin from Chinese shrimp Fenneropenaeus chinensis is responsive to bacteria and WSSV challenge. Fish and Shellfish Immunology 26, 345–351.

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