成瀛，男，博士，西安交通大學生命科學與技術學院副教授，博士生導師。
基本介紹
- 中文名：成瀛
- 畢業院校：中國科學院
- 學位/學歷：博士
- 職業：教師
- 專業方向：中樞神經系統和外周組織對能量穩態調控的研究
- 任職院校：西安交通大學生命科學與技術學院
- 職稱：副教授
研究方向,個人經歷,榮譽獎項,學術成果,
研究方向
1. 中樞神經系統和外周組織對能量穩態調控的研究
2. 線粒體與複雜代謝疾病的研究
個人經歷
2017-至今 西安交通大學生命科學與技術學院， 副教授，博士生導師
2016-2017 美國 費城兒童醫院， Research Associate
2011-2016 美國賓夕法尼亞大學醫學院、費城兒童醫院， 博士後
2010 中國科學院上海生命科學研究院， 博士
2004 西安交通大學生命科學與技術學院， 學士
榮譽獎項
2016 Postdoctoral Fellow Award from University of Pennsylvania School of Medicine and the Children’s Hospital of Philadelphia, USA.
2015 上海市科學技術獎三等獎
2012-2014 Postdoctoral fellowship from American Heart Association
學術成果
Kim, E., Cheng, Y., Bolton-Gillespie, E., Cai, X., Ma, C., Tarangelo, A., Le, L., Jambhekar, M., Raman, P., Hayer, K.E., et al. (2017). Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression. The Journal of experimental medicine 214
Lv, K., Jiang, J., Donaghy, R., Riling, C.R., Cheng, Y., Chandra, V., Rozenova, K., An, W., Mohapatra, B.C., Goetz, B.T., et al. (2017). CBL family E3 ubiquitin ligases control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies. Genes & development 31
Cheng, Y., Chikwava, K., Wu, C., Zhang, H., Bhagat, A., Pei, D., Choi, J.K., and Tong, W. (2016). LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors. The Journal of clinical investigation 126
Zhang, Q., Liu, B., Cheng, Y., Meng, Q., Xia, T., Jiang, L., Chen, S., Liu, Y., and Guo, F. (2014). Leptin signaling is required for leucine deprivation-enhanced energy expenditure. The Journal of biological chemistry 289
Jiang, J., Balcerek, J., Rozenova, K., Cheng, Y., Bersenev, A., Wu, C., Song, Y., and Tong, W. (2012). 14-3-3 regulates the LNK/JAK2 pathway in mouse hematopoietic stem and progenitor cells. The Journal of clinical investigation 122
Xia, T., Cheng, Y., Zhang, Q., Xiao, F., Liu, B., Chen, S., and Guo, F. (2012). S6K1 in the central nervous system regulates energy expenditure via MC4R/CRH pathways in response to deprivation of an essential amino acid. Diabetes 61
Cheng, Y., Zhang, Q., Meng, Q., Xia, T., Huang, Z., Wang, C., Liu, B., Chen, S., Xiao, F., Du, Y., et al. (2011). Leucine deprivation stimulates fat loss via increasing CRH expression in the hypothalamus and activating the sympathetic nervous system. Molecular endocrinology 25
Xiao, F., Huang, Z., Li, H., Yu, J., Wang, C., Chen, S., Meng, Q., Cheng, Y., Gao, X., Li, J., et al. (2011). Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways. Diabetes 60
Cheng, Y., Meng, Q., Wang, C., Li, H., Huang, Z., Chen, S., Xiao, F., and Guo, F. (2010). Leucine deprivation decreases fat mass by stimulation of lipolysis in white adipose tissue and upregulation of uncoupling protein 1 (UCP1) in brown adipose tissue. Diabetes 59
Wang, C., Huang, Z., Du, Y., Cheng, Y., Chen, S., and Guo, F. (2010). ATF4 regulates lipid metabolism and thermogenesis. Cell research 20
