婁曉敏,2009年12月開始 中國科學院北京基因組研究所 副研究員。
基本介紹
基本信息,簡 歷,主要研究領域,代表論著,
基本信息
婁曉敏 ( Xiaomin Lou )
職 稱: 副研究員
職 務: 碩士生導師
研究方向: 腫瘤蛋白質組學
簡 歷
2007年7月-2009年12月 中國科學院北京基因組研究所 助理研究員
主要研究領域
1、863計畫,腫瘤蛋白質分子標誌物的研究與開發,2012-2015,在研,子課題負責人;
2、973計畫,結腸癌及其相關巨噬細胞的分泌蛋白質組與腫瘤發展的相關性研究,2011-2015,在研,子課題負責人;
3、973計畫,腫瘤微環境分泌蛋白質與動物模型和臨床樣本的關聯分析,2011-2015,在研,子課題負責人;
4、國家自然基金,天冬氨酸組織蛋白酶 D 與細胞衰老的關係研究,2009-2011,結題,項目負責人;
5、973計畫,炎症反應信號通路對腫瘤轉移的影響,2009-2013,結題,學術骨幹。
代表論著
1. Liu Y, Ying W, Ren Z, Gu W, Zhang Y, Yan G, Yang P, Liu Y, Yin X, Chang C, Jiang J, Fan F, Zhang C, Xu P, Wang Q, Wen B, Lin L, Wang T, Du C, Zhong J, Wang T, He QY, Qian X*, Lou X*, Zhang G*, Zhong F*. Chromosome-8-Coded Proteome of Chinese Chromosome Proteome Data Set (CCPD) 2.0 with Partial Immunohistochemical Verifications. J Proteome Res
2. Wang Q, Wen B, Wang T, Xu Z, Yin X, Xu S, Ren Z, Hou G, Zhou R, Zhao H, Zi J, Zhang S, Gao H, Lou X, Sun H, Feng Q, Chang C, Qin P, Zhang C, Li N, Zhu Y, Gu W, Zhong J, Zhang G, Yang P, Yan G, Shen H, Liu X, Lu H, Zhong F, He QY, Xu P, Lin L, Liu S. The omics evidences: single nucleotide variants transmissions on Chromosome 20 in liver cancer cell lines. J Proteome Res
3. Zhang S, Wen B, Zhou B, Yang L, Cha C, Xu S, Qiu X, Wang Q, Sun H, Lou X, Zi J, Zhang Y, Lin L, Liu S. Correction to Quantitative Analysis of the Human AKR Family Members in Cancer Cell Lines Using the mTRAQ/MRM Approach. J Proteome Res
4. Sun H, Lou X, Shan Q, Zhang J, Zhu X, Zhang J, Wang Y, Xie Y, Xu N, Liu S. Proteolytic characteristics of cathepsin D related to the recognition and cleavage of its target proteins. PLoS One
5. Yang L, Zhang J, Zhang S, Dong W, Lou X, Liu S. Quantitative Evaluation of Aldo–keto Reductase Expression in Hepatocellular Carcinoma (HCC) Cell Lines. Genomics, Proteomics & Bioinformatics
6. Zhang S, Wen B, Zhou B, Yang L, Cha C, Xu S, Qiu X, Wang Q, Sun H, Lou X, Zi J, Zhang Y, Lin L, Liu S. Quantitative analysis of the human AKR family members in cancer cell lines using the mTRAQ/MRM approach. J Proteome Res
7. Wang Q, Wen B, Yan G, Wei J, Xie L, Xu S, Jiang D, Wang T, Lin L, Zi J, Zhang J, Zhou R, Zhao H, Ren Z, Qu N, Lou X, Sun H, Du C, Chen C, Zhang S, Tan F, Xian Y, Gao Z, He M, Chen L, Zhao X, Xu P, Zhu Y, Yin X, Shen H, Zhang Y, Jiang J, Zhang C, Li L, Chang C, Ma J, Yan G, Yao J, Lu H, Ying W, Zhong F, He QY, Liu S. Qualitative and quantitative expression status of the human chromosome 20 genes in cancer tissues and the representative cell lines. J Proteome Res.
8. Shan Q, Lou X, Xiao T, Zhang J, Sun H, Gao Y, Cheng S, Wu L, Xu N, Liu S. A cancer/testis antigen microarray to screen autoantibody biomarkers of non-small cell lung cancer. Cancer Lett
9. Zhang X, Wang Q, Lou X, Sun H, Roepstorff P, Liu S. An on-target desalting and concentration sample preparation protocol for MALDI-MS and MS/MS analysis. Methods Mol Biol.
10. Zhang J, Lou X, Yang S, He S, Yang L, Liu M, Zhu H, Shan Q, Su S, Zhan Q, Xu N, Liu S. BAG2 is a target of the c-Myc gene and is involved in cellular senescence via the p21(CIP1) pathway. Cancer Lett.
11. 房亞哲, 劉津, 吳琳, 婁曉敏, 趙冠飛, 張洪濤, 陳文明, 王清濤. 用尿液蛋白質組技術篩選多發性骨髓瘤相關蛋白的初步研究. 中國實驗診斷學,04期
12. Yan S, Zhou C, Lou X, Xiao Z, Zhu H, Wang Q, Wang Y, Lu N, He S, Zhan Q, Liu S, Xu N. PTTG overexpression promotes lymph node metastasis in human esophageal squamous cell carcinoma. Cancer Res
13. Lou X, Xiao T, Zhao K, Wang H, Zheng H, Lin D, Lu Y, Gao Y, Cheng S, Liu S, Xu N. Cathepsin D is secreted from M-BE cells: its potential role as a biomarker of lung cancer. J Proteome Res