唐海寶，2009年12月獲得美國喬治亞大學（University of Georgia）植物學博士學位。
現為福建農林大學海外引進人才（兼職），福建百人計畫，福建農林大學博士生導師，兼職教授。
2009年12月獲得美國喬治亞大學（University of Georgia）植物學博士學位。在古生物基因組學、比較基因組、資料庫開發等研究領域取得優異的成績，是基因組序列裝配、基因注釋、資料庫建設、基因組比較分析方面的專家。先後在《Science》、《Nature》、《PNAS》、《Nature Genetics》、《The Plant Cell 》、《Genome Research》等國際學術期刊發表文章39篇。
基本介紹
- 中文名：唐海寶
- 國籍：中國
- 民族：漢
- 職業：教授
- 畢業院校：復旦大學，喬治亞大學
人物生平,主要成就,出版著作,
人物生平
2000到2004年 復旦大學本科
2009年12月 獲得美國喬治亞大學（University of Georgia）植物學博士學位
主要成就
1. 發現並推測被子植物進化中發生的多次古代基因組複製（多倍化）事件並闡述單雙子葉植物基因組結構和基因家族的進化過程。該項研究對於推測基因組間同源區段以及同源基因有非常重要的意義。
2.在比較基因組學領域發明了新的算法和軟體，其中MCSCAN，QUOTA-ALIGN已經成為很多基因組項目用於基因組比較的必備軟體並被引用上百次。開發了高性能的生物信息學分析平台和資料庫，比如植物基因組複製資料庫(PGDD)，以及COGE比較基因組分析平台。
3. 參加了多項植物基因組裝配及分析工作，包括木瓜，高粱，苜蓿，白菜，花菜，油菜，番茄，棉花，柳樹，Amborella，蓮花等14項重要基因組項目。尤其對於雜合度高或者多倍體的複雜基因組裝配及分析處於領先水平。
4. 定位和克隆禾本科作物馴化過程中的重要基因。通過基因組關聯性分析和圖位克隆的手段，發現高粱的花期基因和脫粒基因。發現並闡明了在多倍體物種里亞基因組的相互作用和染色體間協同進化方式。
出版著作
39) Paterson, AH, …, Tang, H, …, Schmutz, J (2012) Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature, doi:10.1038/nature11798
38) Lee, TH, Tang, H, Wang, X, Paterson, AH (2012) PGDD: a database of gene and genome duplication in plants. Nucleic Acids Research, 1–7, doi:10.1093/nar/gks1104
36) Tang, H, Lyons, E (2012) The Evolution of Genome Structure. Int J Evol, 1:1 (Editorial)
35) Lu, J, Peatman, E, Tang, H, Lewis, J, Liu, Z (2012) Profiling of gene duplication patterns of sequenced teleost genomes: evidence for rapid lineage-specific genome expansionmediated by recent tandem duplications. BMC Genomics, 13: 246.
34) Sato, S, …, Tang, H, …, Klein Lankhorst, RM (2012) The tomato genome sequence provides insights into fleshy fruit evolution.Nature, 485: 635-641.
33) Tang, H, Woodhouse, MR, Cheng, F, Schnable, JC, Pedersen, BS, et al. (2012) Altered patterns of fractionation and exon deletions in Brassica rapa support a two-step model of paleohexaploidy. Genetics, 190:1563-1574 (First Author).
32) Wang, Y*, Tang, H*, Debarry, JD, Tan, X, Li, J, et al. (2012) MCScanX: a toolkit for detection and evolutionary analysis of gene synteny and collinearity. Nucleic Acids Research, 40: e49 (co-First Author).
31) Woodhouse, MR, Tang, H, Freeling, M. (2011) Different gene families inArabidopsis thalianatransposed in different epochs and at different frequencies throughout the rosids. Plant cell, 23: 4241-4253.
30) Wang, Y, Wang, X, Tang, H, Tan, X, Ficklin, SP, et al. (2011) Modes of Gene Duplication Contribute Differently to genetic novelty and redundancy, but show parallels across divergent angiosperms. PLoS One, 6: e28150.
29) Young, ND, …, Tang, H, …, Roe, B (2011) The medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 480: 520-524.
28) Wang, X, …, Tang, H, …, Zhang, Z (2011) The genome of the mesopolyploid crop species Brassica rapa. Nature Genetics, 43: 1035-1039.
27) Zuccolo, A, …, Tang, H, …, Leebens-Mack, J (2011) A physical map for the Amborella trichopoda genome sheds light on the evolution of angiosperm genome structure. Genome Biology, 12: R48.
26) Ratnaparkhe, MB, …, Tang, H, …, Paterson, AH (2011) Comparative analysis of peanut NBSLRR gene clusters suggests evolutionary innovation among duplicated domains and erosion of gene microsynteny. New Phytologist, 192: 164-178.
25) Lin, L, Tang, H, Compton, RO, Lemke, C, Rainville, LK, et al. (2011) Comparative analysis of Gossypium and Vitis genomes indicates genome duplication specific to the Gossypium lineage. Genomics, 97: 313-320.
24) Pedersen, BS, Tang, H, Freeling, M (2011) Gobe: an interactive, web-based tool for comparative genomic visualization.Bioinformatics, 27(7):1015-6.
23) Wang, X, Tang, H, Paterson, AH (2011) Seventy million years of concerted evolution of a homoeologous chromosome pair, in parallel, in major Poaceae lineages. Plant Cell, 23(1):27-37.
22) Tang, H, Lyons E, Pedersen B, Schnable JC, Paterson AH, Freeling M (2011) Screening synteny blocks in pairwise genome comparisons through integer programming. BMC Bioinformatics, 12: 102 (First Author).
21) Tang, H, Sezen, U, and Paterson, AH (2010) Domestication and plant genomes. Current Opinion in Plant Biology, 13(2):160-6(First Author).
20) Tang, H, Bowers, JE, Wang, X, and Paterson, AH (2010) Angiosperm genome comparisons reveal early polyploidy in the monocot lineage. PNAS, 107(1): 472-7 (First Author).
19) Lin, L, …, Tang, H, …, Paterson, AH (2010) A draft physical map of a D-genome cotton species (Gossypium raimondii). BMC Genomics, 11(1):395.
18) Paterson, AH, Freeling, M, Tang, H, Wang, X (2010) Insights from the comparison of plant genome sequences. Annual Review of Plant Biology, 61: 349-72.
17) Wang, J, …, Tang, H, …, Ming R (2010) Microcollinearity between autopolyploid sugarcane and diploid sorghum genomes. BMC Genomics, 11(1): 261.
16) Li, G, Ma, Q, Tang, H, Paterson, AH and Xu, Y (2009) QUBIC: a qualitative biclustering algorithm for analyses of gene expression data. Nucleic Acid Research, 37: e101.
15) Charles, M, Tang, H, Belcram H, Paterson A, Gornicki P, et al. (2009) Sixty million years in evolution of soft grain trait in grasses: emergence of the softness locus in the common ancestor of Pooideae and Ehrhartoideae, after their divergence from Panicoideae. Molecular Biology and Evolution, 26: 1651-1661.
14) Wang, X, Tang, H, Bowers, JE, Paterson, AH (2009) Comparative inference of illegitimate recombination between rice and sorghum duplicated genes produced by polyploidization. Genome Research, 19: 1026-1032.
13) Paterson, AH, Bowers, JE, Feltus, FA, Tang, H, Lin, L, Wang, X (2009) Comparative genomics of the grasses: Promising a bountiful harvest. Plant Physiology, 149, 125-131.
12) Paterson, AH, …, Tang, H, …, Rokhsar, DS (2009) The Sorghum bicolor genome and the diversification of grasses. Nature, 457, 551-556.
11) Wang, X, Gowik, U, Tang, H, Bowers, JE, Westhoff, P, Paterson, AH (2009) Comparative genomic analysis of C4 photosynthetic pathway evolution in grasses. Genome Biology, 10: R68.
10) Kim, C, Tang, H and Paterson, AH (2009) Duplication and Divergence of Grass Genomes: Integrating the Chloridoids. Tropical Plant Biology, 2, 51-62.
9) Che, D, Tang, H and Song, Y (2009) Haplotype inference using a genetic algorithm. Proceedings of IEEE Bioinformatics and Computational Biology, 31-37.
8) Lyons, E, …, Tang, H, …, Freeling, M (2008) Finding and Comparing Syntenic Regions among Arabidopsis and the Outgroups Papaya, Poplar, and Grape: CoGe with Rosids. Plant Physiology, 148, 1772-81.
7) Jang, CS, Kamps, TL, Tang, H, Bowers, JE, Lemke, C, Paterson, AH (2008) Evolutionary fate of rhizome-specific genes in a non-rhizomatous Sorghum genotype. Heredity 102: 266-273.
6) Tang H, Bowers JE, Wang X, Ming R, Alam M, Paterson AH (2008) Synteny and Collinearity in Plant Genomes, Science, 320, 486-488 (First Author).
5) Tang H, Wang X, Bowers JE, Ming R, Alam M, Paterson AH (2008) Unraveling ancient hexaploidy through multiply-aligned angiosperm gene maps, Genome Research, 18, 1944-1954 (First Author).
4) Ming, R, ..., Tang, H, …, Alam M (2008) The draft genome of the transgenic tropical fruit tree papaya (Carica papaya Linnaeus),Nature, 452, 991-996.
3) Wang, X, Tang, H, Bowers, JE, Feltus, FA, Paterson, AH (2007) Extensive concerted evolution of rice paralogs and the road to regaining independence, Genetics, 177, 1753-1763.
2) Liu, Q, Ge, S, Tang, H, Zhang, X, Zhu, G, Lu, BR (2006) Phylogenetic relationships in Elymus (Poaceae: Triticeae) based on the nuclear ribosomal internal transcribed spacer and chloroplast trnL-F sequences, New Phytologist, 170, 411-420.
1) Bowers, JE, …, Tang, H, Wing, RA, Paterson, AH. (2005) Comparative physical mapping links conservation of microsynteny to chromosome structure and recombination in grasses, PNAS, 102, 13206-13211
38) Lee, TH, Tang, H, Wang, X, Paterson, AH (2012) PGDD: a database of gene and genome duplication in plants. Nucleic Acids Research, 1–7, doi:10.1093/nar/gks1104
36) Tang, H, Lyons, E (2012) The Evolution of Genome Structure. Int J Evol, 1:1 (Editorial)
35) Lu, J, Peatman, E, Tang, H, Lewis, J, Liu, Z (2012) Profiling of gene duplication patterns of sequenced teleost genomes: evidence for rapid lineage-specific genome expansionmediated by recent tandem duplications. BMC Genomics, 13: 246.
34) Sato, S, …, Tang, H, …, Klein Lankhorst, RM (2012) The tomato genome sequence provides insights into fleshy fruit evolution.Nature, 485: 635-641.
33) Tang, H, Woodhouse, MR, Cheng, F, Schnable, JC, Pedersen, BS, et al. (2012) Altered patterns of fractionation and exon deletions in Brassica rapa support a two-step model of paleohexaploidy. Genetics, 190:1563-1574 (First Author).
32) Wang, Y*, Tang, H*, Debarry, JD, Tan, X, Li, J, et al. (2012) MCScanX: a toolkit for detection and evolutionary analysis of gene synteny and collinearity. Nucleic Acids Research, 40: e49 (co-First Author).
31) Woodhouse, MR, Tang, H, Freeling, M. (2011) Different gene families inArabidopsis thalianatransposed in different epochs and at different frequencies throughout the rosids. Plant cell, 23: 4241-4253.
30) Wang, Y, Wang, X, Tang, H, Tan, X, Ficklin, SP, et al. (2011) Modes of Gene Duplication Contribute Differently to genetic novelty and redundancy, but show parallels across divergent angiosperms. PLoS One, 6: e28150.
29) Young, ND, …, Tang, H, …, Roe, B (2011) The medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 480: 520-524.
28) Wang, X, …, Tang, H, …, Zhang, Z (2011) The genome of the mesopolyploid crop species Brassica rapa. Nature Genetics, 43: 1035-1039.
27) Zuccolo, A, …, Tang, H, …, Leebens-Mack, J (2011) A physical map for the Amborella trichopoda genome sheds light on the evolution of angiosperm genome structure. Genome Biology, 12: R48.
26) Ratnaparkhe, MB, …, Tang, H, …, Paterson, AH (2011) Comparative analysis of peanut NBSLRR gene clusters suggests evolutionary innovation among duplicated domains and erosion of gene microsynteny. New Phytologist, 192: 164-178.
25) Lin, L, Tang, H, Compton, RO, Lemke, C, Rainville, LK, et al. (2011) Comparative analysis of Gossypium and Vitis genomes indicates genome duplication specific to the Gossypium lineage. Genomics, 97: 313-320.
24) Pedersen, BS, Tang, H, Freeling, M (2011) Gobe: an interactive, web-based tool for comparative genomic visualization.Bioinformatics, 27(7):1015-6.
23) Wang, X, Tang, H, Paterson, AH (2011) Seventy million years of concerted evolution of a homoeologous chromosome pair, in parallel, in major Poaceae lineages. Plant Cell, 23(1):27-37.
22) Tang, H, Lyons E, Pedersen B, Schnable JC, Paterson AH, Freeling M (2011) Screening synteny blocks in pairwise genome comparisons through integer programming. BMC Bioinformatics, 12: 102 (First Author).
21) Tang, H, Sezen, U, and Paterson, AH (2010) Domestication and plant genomes. Current Opinion in Plant Biology, 13(2):160-6(First Author).
20) Tang, H, Bowers, JE, Wang, X, and Paterson, AH (2010) Angiosperm genome comparisons reveal early polyploidy in the monocot lineage. PNAS, 107(1): 472-7 (First Author).
19) Lin, L, …, Tang, H, …, Paterson, AH (2010) A draft physical map of a D-genome cotton species (Gossypium raimondii). BMC Genomics, 11(1):395.
18) Paterson, AH, Freeling, M, Tang, H, Wang, X (2010) Insights from the comparison of plant genome sequences. Annual Review of Plant Biology, 61: 349-72.
17) Wang, J, …, Tang, H, …, Ming R (2010) Microcollinearity between autopolyploid sugarcane and diploid sorghum genomes. BMC Genomics, 11(1): 261.
16) Li, G, Ma, Q, Tang, H, Paterson, AH and Xu, Y (2009) QUBIC: a qualitative biclustering algorithm for analyses of gene expression data. Nucleic Acid Research, 37: e101.
15) Charles, M, Tang, H, Belcram H, Paterson A, Gornicki P, et al. (2009) Sixty million years in evolution of soft grain trait in grasses: emergence of the softness locus in the common ancestor of Pooideae and Ehrhartoideae, after their divergence from Panicoideae. Molecular Biology and Evolution, 26: 1651-1661.
14) Wang, X, Tang, H, Bowers, JE, Paterson, AH (2009) Comparative inference of illegitimate recombination between rice and sorghum duplicated genes produced by polyploidization. Genome Research, 19: 1026-1032.
13) Paterson, AH, Bowers, JE, Feltus, FA, Tang, H, Lin, L, Wang, X (2009) Comparative genomics of the grasses: Promising a bountiful harvest. Plant Physiology, 149, 125-131.
12) Paterson, AH, …, Tang, H, …, Rokhsar, DS (2009) The Sorghum bicolor genome and the diversification of grasses. Nature, 457, 551-556.
11) Wang, X, Gowik, U, Tang, H, Bowers, JE, Westhoff, P, Paterson, AH (2009) Comparative genomic analysis of C4 photosynthetic pathway evolution in grasses. Genome Biology, 10: R68.
10) Kim, C, Tang, H and Paterson, AH (2009) Duplication and Divergence of Grass Genomes: Integrating the Chloridoids. Tropical Plant Biology, 2, 51-62.
9) Che, D, Tang, H and Song, Y (2009) Haplotype inference using a genetic algorithm. Proceedings of IEEE Bioinformatics and Computational Biology, 31-37.
8) Lyons, E, …, Tang, H, …, Freeling, M (2008) Finding and Comparing Syntenic Regions among Arabidopsis and the Outgroups Papaya, Poplar, and Grape: CoGe with Rosids. Plant Physiology, 148, 1772-81.
7) Jang, CS, Kamps, TL, Tang, H, Bowers, JE, Lemke, C, Paterson, AH (2008) Evolutionary fate of rhizome-specific genes in a non-rhizomatous Sorghum genotype. Heredity 102: 266-273.
6) Tang H, Bowers JE, Wang X, Ming R, Alam M, Paterson AH (2008) Synteny and Collinearity in Plant Genomes, Science, 320, 486-488 (First Author).
5) Tang H, Wang X, Bowers JE, Ming R, Alam M, Paterson AH (2008) Unraveling ancient hexaploidy through multiply-aligned angiosperm gene maps, Genome Research, 18, 1944-1954 (First Author).
4) Ming, R, ..., Tang, H, …, Alam M (2008) The draft genome of the transgenic tropical fruit tree papaya (Carica papaya Linnaeus),Nature, 452, 991-996.
3) Wang, X, Tang, H, Bowers, JE, Feltus, FA, Paterson, AH (2007) Extensive concerted evolution of rice paralogs and the road to regaining independence, Genetics, 177, 1753-1763.
2) Liu, Q, Ge, S, Tang, H, Zhang, X, Zhu, G, Lu, BR (2006) Phylogenetic relationships in Elymus (Poaceae: Triticeae) based on the nuclear ribosomal internal transcribed spacer and chloroplast trnL-F sequences, New Phytologist, 170, 411-420.
1) Bowers, JE, …, Tang, H, Wing, RA, Paterson, AH. (2005) Comparative physical mapping links conservation of microsynteny to chromosome structure and recombination in grasses, PNAS, 102, 13206-13211
