何承勇:人物經歷,主講課程,研究方向,學術成果,科研課題,改革項目,論文,

何承勇，畢業於廈門大學，博士，廈門大學生命科學學院副教授，主要研究方向為環境毒理學，納米毒理學等。

基本介紹

中文名：何承勇
畢業院校：廈門大學
學位/學歷：博士
職業：教師
專業方向：環境毒理學、納米毒理學、環境污染物毒性作用及機制研究
任職院校：廈門大學生命科學學院

人物經歷,主講課程,研究方向,學術成果,科研課題,改革項目,論文,

人物經歷

2003/09-2007/06，南京農業大學，無錫漁業學院，本科

2007/09–2009/09，廈門大學，生命科學學院，碩士研究生

2011/09–2012/08，Molecular and Environmental Toxicology Center, University of Wisconsin-Madison, USA國家留學基金委公派聯合培養博士

2009/09–2012/12，廈門大學，生命科學學院生物學系動物學，博士

2013/01–2017/07，廈門大學，公共衛生學院預防醫學系，助理教授

2017/08–2018/07，廈門大學，公共衛生學院預防醫學系，副教授

2018/08–至今，廈門大學，生命科學學院生物學系，副教授

主講課程

本科生課程：《動物生理學》《毒理學基礎》、《毒理學實驗技術與方法》、《公共衛生人文案例》、《環境生理學》、《環境因素與健康》等

研究生課：《生命科學前沿》《現代實驗預防醫學》、《毒理學教程》、《高級職業病學》等

研究方向

環境毒理學；納米毒理學

環境污染物毒性作用及機制研究；納米生物安全性評價

學術成果

科研課題

1. 國家自然科學基金面上項目，32071301，Kyn/AhR通路調控T細胞活化促進黑磷量子點誘導腎臟損傷的分子機制，2021/01-2024/12，在研，主持

2. 國家自然科學基金青年項目，81402648，多環芳烴通過NO介導的亞硝基化影響海馬神經發育的機制研究，2015/01-2017/12，已結題，主持

3. 廈門大學校長基金，20720180045，未摺疊蛋白反應ATF4通路調控內質網自噬介導量子點腎損傷機制研究與套用，2018/1-2020/12，在研，主持

4. 國家重點研究計畫，“肝癌高特異性近紅外納米成像探針的設計與合成”，2017-2020，在研，參加

改革項目

第三學期本科生系列學術沙龍的探索與實踐

論文

1. Chengyong He*, Fengkai Ruan, Shengwei Jiang, Jie Zeng, Hanying Yin, Rong Liu, Yongxing Zhang, Laiqiang Huang, Chonggang Wang, Shaohua Ma*, Zhenghong Zuo*. Black Phosphorus Quantum Dots Cause Nephrotoxicity in Organoids, Mice and Human Cells. Small. 2020, 2001371 (IF=11.4, JCR1區).

2. Chengyong He, Shengwei Jiang, Haijing Jin, Shuzhen Chen, Gan Lin, Huan Yao, Xiaoyong Wang, Peng Mi, Zhiliang Ji, Yuchun Lin*, Zhongning Lin*, Gang Liu*. Mitochondrial electron transport chain identified as a novel molecular target of SPIO nanoparticles mediated cancer-specific cytotoxicity. Biomaterials. 2016;83:102-114. (IF=10.3, JCR1區)

3.Fengkai Ruan, Rong Liu, Jie Zeng, Kai Wang, Zhenghong Zuo, Chengyong He*, Yongxing Zhang*, Cytotoxicity of black phosphorus quantum dots on lung-derived cells and the underlying mechanisms. Journal of Hazardous Materials. jhazmat.2020.122875 (IF=9.03, JCR1區)

4.Shengwei Jiang, Yuchun Lin, Huan Yao, Chuanli Yang, Liyin Zhang, Bing Luo, Zhao Lei, Liwei Cao, Naibo Lin, Xiangyang Liu*, Zhongning Lin*, Chengyong He*. The role of unfolded protein response and ER-phagy in quantum dots-induced nephrotoxicity: an in vitro and in vivo study. Archives of Toxicology. 2018;92(541) 1-14. (IF=5.05, JCR1區)

5.Chengyong He, Shengwei Jiang, Huan Yao, Liyin Zhang, Chuanli Yang, Denglin Zhan, Gan Lin, Yun Zeng, Yankai Xia, Zhongning Lin*, Gang Liu*, Yuchun Lin*. Endoplasmic reticulum stress mediates inflammatory response triggered by ultra-small superparamagnetic iron oxide nanoparticles in hepatocytes. Nanotoxicology. 2018;12(10): 1198-1214. (IF=4.92, JCR1區)

6.Chengyong He, Shengwei Jiang, Huan Yao, Liyin Zhang, Chuanli Yang, Shan Jiang, Fengkai Ruan, Denglin Zhan, Gang Liu, Zhongning Lin*, Yuchun Lin*,Xiaoyuan Chen. High-content analysis for mitophagy response to nanoparticles: A potential sensitive biomarker for nanosafety assessment. Nanomedicine-Nanotechnology Biology and Medicine. 2019 Jan;15(1):59-69. (IF=5.18, JCR1區)

7.Mei Chen, Shuzhen Chen, Chengyong He, Shiguang Mo, Xiaoyong Wang, Gang Liu*, and Nanfeng Zheng*, Safety profile of two-dimensional Pd nanosheets for photothermal therapy and photoacoustic imaging. Nano Research. 2017;10(4): 1234–1248. (IF=8.18, JCR1區)

8.Chengyong He, Yang Qiu, Peiyu Han, Yuanyuan Chen, Liyin Zhang, Quan Yuan, Tianying Zhang, Tong Cheng, Lunzhi Yuan, Chenghao Huang, Sheng Zhang, Zhenyu Yin, Xian-E Peng, Dong Liang, Xu Lin, Yuchun Lin*, Zhongning Lin*, and Ningshao Xia. ER stress regulating protein phosphatase 2A-B56γ, targeted by hepatitis B virus X protein, induces cell cycle arrest and apoptosis of hepatocytes. Cell Death & Disease. 2018. Jul 9;9(7):762. (IF=6.3, JCR2區)

9.Bing Luo, Yuchun Lin, Shengwei Jiang, Lianyun Huang, Huan Yao, Qunying Zhuang, Ran Zhao, Hengchuan Liu, Chengyong He*, Zhongning Lin*. Endoplasmic reticulum stress eIF2α-ATF4 pathway-mediated cyclooxygenase-2 induction regulates cadmium-induced autophagy in kidney. Cell Death & Disease. 2016;7: e2251; doi:10.1038/cddis.2016.78. (IF=6.3, JCR2區)

10.Chuanli Yang, Peiyu Han, Fengkai Ruan, Tengjian Zhou, Bing Luo, Yang Qiu, Yuchun Lin, Zhongning Lin*, Chengyong He*. Lactational exposure to environmentally relevant benzo(a)pyrene causes astrocytic activation and anxiety-like behavior in male mice. Chemosphere. 2019.221: 67e74. (IF=5.778, JCR2區)

11. Chen Tang, Chao Shen, Kongyang Zhu, Yixi Zhou, Yung-Jen Chuang, Chengyong He∗, Zhenghong Zuo*. Exposure to the AhR agonist cyprodinil impacts the cardiac development and function of zebrafish larvae. Ecotoxicology and Environmental Safety 201 (2020) 110808 (IF=4.87, JCR2區)

12. Naying Zheng, Jinhui Yan, Wang Qian, Chao Song, Zhenghong Zuo, Chengyong He*. Comparison of developmental toxicity of different surface modified CdSe/ZnS QDs in zebrafish embryos. Journal of Environmental Sciences-China 2021.10.1016/j.jes.2020.07.019 (IF=4.302, JCR2區)

13.Jinhui Yan, Shujing Chen, Zhenghong Zuo, Chengyong He*, Muqing Yi*. Graphene oxide quantum dot exposure induces abnormalities in locomotor activities and mechanisms in zebrafish (Danio rerio). Journal of Applied Toxicology. 2020;40:794–803. (IF=2.997, JCR2區)

14.Chengyong He, Zhenghong Zuo, Xiao Shi, Lingbin Sun, Chonggang Wang*, Pyrene exposure influences the thyroid development of Sebastiscus marmoratus embryos. Aquatic Toxicology. 2012:124-125C;28-33. (IF=4.344, JCR2區)

15.Chengyong He, Chonggang Wang, Bowen Li, Meifang Wu, Hong Geng, Yixin Chen, Zhenghong Zuo*. Exposure of Sebastiscus marmoratus embryos to pyrene results in neurodevelopmental defects and disturbs related mechanisms. Aquatic Toxicology. 2012;116-117: 109-115. (IF=4.344, JCR2區)

16.Chengyong He, Zhenghong Zuo, Xiao Shi, Ruixia Li, Donglei Chen, Xin Huang, Yixin Chen, Chonggang Wang*. Effects of Benzo(a)Pyrene on the skeletal development of Sebastiscus marmoratus embryos and the molecular mechanism involved. Aquatic Toxicology. 2011;101:335–341. (IF=4.344, JCR2區)

17.Chengyong He, Chonggang Wang, Yulin Zhou, Jian Li, Zhenghong Zuo*. Embryonic exposure to benzo(a)pyrene influences neural development and function in rockfish (Sebastiscus marmoratus). Neurotoxicology. 2012; 33:758-762. (IF=3.105, JCR3區)

18.Chengyong He, Chonggang Wang, Bowen Li, Fazhi Xie, Yixin Chen, Zhenghong Zuo*. Tissue-specific and embryonic expression of the retinoid X receptors in Sebastiscus marmoratus. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 2009; 154(2):221-228. (IF=2.219, JCR4區)

19.Junxia Shi, Chenyu Liu, Mingyue Chen, Jinhui Yan, Chonggang Wang, Zhenghong Zuo, Chengyong He*. The interference effects of bisphenol A on the synthesis of steroid hormones in human ovarian granulosa cells. Environmental Toxicology. (Nov. 2020, Accepted) (IF=3.118, JCR3區)

20.Kongyang Zhu, Chao Shen, Chen Tang, Yixi Zhou, Chengyong He*, Zhenghong Zuo*. Improvement in the screening performance of potential aryl hydrocarbon receptor ligands by using supervised machine learning. Chemosphere. (Nov. 2020, Accepted) (IF=5.778, JCR2區)

何承勇