ProSci Incorporated 於1998年成立於世界生物城之一的美國加州聖地亞哥市，從事抗體等科研試劑的研發、生產和銷售。
基本介紹
- 公司名稱：prosci
- 總部地點：美國加州聖地亞哥市
- 成立時間：1998年
- 經營範圍：抗體等科研試劑的研發
簡介,發展歷史,優勢,
簡介
1. ProSci Incorporated
ProSci是世界最早和最大的細胞凋亡抗體生產廠家和供應商，公司現擁有17000多種單、多克隆抗體，產品涵蓋了細胞凋亡、信號轉導、免疫、腫瘤、細胞生物、神經生物、傳染病等領域。公司的抗體大都經免疫親和層析純化，具有高純度、高親和力、特異性強等特點，所有的ProSci抗體都經過了嚴格的驗證測試和質量控制，已保證高質量的產品。
發展歷史
ProSci的抗體廣銷於世界30多個國家和地區，得到歐美日等生物醫學界科研人員和生物製藥公司的研發人員的廣泛接受。ProSci的產品已套用在1281篇SCI論文中，其中2011年的有228篇，ProSci的經銷商和客戶都對ProSci的產品質量和服務十分滿意。我們的抗體可用於免疫印跡（Western blot），免疫組織化學（IHC），免疫細胞化學（ICC），酶聯免疫吸附實驗（ELISA）和細胞流式分析（FACS）等方面。此外，ProSci還提供標記二抗，重組蛋白，細胞和組織裂解液，細胞塗片，組織切片，多肽等產品與抗體配套使用。ProSci在美國擁有完整的免疫學試劑開發、生產、檢測的生產線，包括自己的廠房和實驗動物基地，可為您的研究提供信得過的抗體等科研試劑。
2. 普賽生物（蘇州）有限公司
普賽生物（蘇州）有限公司是美國ProSci在國內的全資子公司，位於蘇州工業園區東南大學蘇州研究院。自2010年9月成立後短短的幾個月內，產品銷售已遍及全國。普賽生物擁有高品質和高覆蓋率的抗體庫，將為國內的科研單位提供所有美國公司原裝進口的優質抗體產品。
優勢
ProSci致力於給全世界生物醫藥領域的科學家們提供最好的抗體等科研試劑產品，並努力成為他們研究的首選和最好的夥伴。
這是我們一直為之努力的優質服務
·可靠的產品質量和全面的說明書
·詳細準確且不斷更新的數據資料
·豐富的線上資源和全面的技術支持
·快捷可靠的物流運輸
·專業的技術人員提供的優質售後服務
4. 質量保證和產品套用文獻
ProSci的客戶包括美國國立衛生研究院（NIH），美國國家疾控中心（CDC），麻省理工學院（MIT），耶魯大學以及諾華製藥等許多知名大學研究機構和製藥公司，國內的客戶有：中科院上海生科院，中國國家疾控中心，中國醫學科學院北京協和醫院，香港大學巴斯德研究所等等。ProSci的產品已套用在1281篇SCI論文中，其中2011年的有228篇，ProSci的經銷商和客戶都對ProSci的產品質量和服務十分滿意，ProSci公司在2003、2007、2010年度，都被《Nature》評為最佳抗體研發、生產和服務供應商。
發表雜誌名稱 | 套用文獻數 | 影響因子 |
Nature | 4 | 35.74 |
Cell | 7 | 32.4 |
Nature Immunology | 7 | 25.66 |
Journal of Experimental medicine | 8 | 14.77 |
Molecular Cell | 7 | 14.19 |
Journal of Molecular Cell Biology | 15 | 13.4 |
Genes & Development | 4 | 12.88 |
Gut | 8 | 10.61 |
Blood | 24 | 10.56 |
The EMBO Journal | 7 | 10.12 |
Journal of Cell Biology | 11 | 9.92 |
PNAS | 28 | 9.77 |
Circulation research | 6 | 9.5 |
Cell Death and Differentiation | 30 | 9.05 |
Cancer research | 63 | 8.23 |
Oncogene | 18 | 7.41 |
Journal of Neuroscience | 17 | 7.27 |
Faseb Journal | 6 | 6.5 |
Journal of Cell science | 8 | 6.29 |
Journal of Immunology | 34 | 5.75 |
The Journal of Biological chemistry | 93 | 5.33 |
Molecular cancer therapeutics | 11 | 5.22 |
The American Journal of Pathology | 10 | 5.22 |
Journal of Virology | 31 | 5.19 |
ProSci 2011年部分最新產品套用文獻
1. Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways. Liyun Sang et al. Cell,13 May 2011 145(4) pp. 513 - 528. TCTN2 antibody (ProSci, San Diego, California, USA)
2. Functional complementation between FADD and RIP1 in embryos and lymphocytes.Haibing Zhang et al. Nature, 2 March 2011 471, 373-376. RIP3 antibody (ProSci, San Diego, California, USA)
3. Mechanisms of necroptosis in T cells. Irene L. Ch’en et al.J. Exp. Med., Apr 2011; 208: 633 - 641.Ripk3 antibody (ProSci Inc.).
4. SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell. Xianpei Jia et al.J Mol Cell Biol, Aug 2011; 3: 230 - 238. Antibodies used included polyclonal anti-SOX2, STIM1 (ProSci Inc.), Orai1 (ProSci Inc.).
5. DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria.Lisa S. Shock et al.PNAS, Mar 2011; 108: 3630 - 3635. Cells were transfected using Polyjet liposomes (ProSci) (HCT116).
6. Disruption of Src function potentiates Chk1-inhibitor–induced apoptosis in human multiple myeloma cells in vitro and in vivo. Yun Dai et al.Blood, Feb 2011; 117: 1947 - 1957. expression of Bim using an antibody (ProSci).
7. Proteomic analysis identifies galectin-1 as a predictive biomarker for relapsed/refractory disease in classical Hodgkin lymphoma. Peter Kamper et al.Blood, Jun 2011; 117: 6638 - 6649. anti-GNAI3 (XW-7212; WB dilution 1:200 ProSci Incorporated).
8. Antiviral memory CD8 T-cell differentiation, maintenance, and secondary expansion occur independently of MyD88. Adeeb H. Rahman et al.Blood, Mar 2011; 117: 3123 - 3130.probed with rabbit anti-mouse MyD88 antibody (2127; ProSci).
9. Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-B–inducing kinase while activating both canonical and alternative nuclear factor-B pathways.Lan V. Pham et al.Blood, Jan 2011; 117: 200 - 210. polyclonal BR3 (ProSci).
10. Store-Operated Ca2+ Entry in Sensory Neurons: Functional Role and the Effect of Painful Nerve Injury. Geza Gemes et al.J. Neurosci., Mar 2011; 31: 3536 - 3549. anti-STIM1 rabbit polyclonal antibody (1:500; ProSci; catalog #4119), and anti-Orai1 rabbit polyclonal antibody (1:1000; ProSci, catalog #4281).
11. β-Agonist-associated Reduction in RGS5 Expression Promotes Airway Smooth Muscle Hyper-responsiveness.Zhao Yang et al.J. Biol. Chem., Apr 2011; 286: 11444 - 11455. anti-RGS5 primary antibody (Prosci, 1:250).
12. Bit-1 Mediates Integrin-dependent Cell Survival through Activation of the NFB Pathway. Genevieve S. Griffiths et al.J. Biol. Chem., Apr 2011; 286: 14713 - 14723. rabbit anti-Bit-1 polyclonal antibody (1:100; ProSci) or anti-FAK antibody (1:100; ProSci).
13. Painful Pathways Induced by TLR Stimulation of Dorsal Root Ganglion Neurons.Jia Qi et al.J. Immunol., Jun 2011; 186: 6417 - 6426. rabbit polyclonal Ab against TLR3, TLR7, and TLR9 (1:1000; Prosci, Poway, CA).
14. The C Proteins of Human Parainfluenza Virus Type 1 Limit Double-Stranded RNA Accumulation That Would Otherwise Trigger Activation of MDA5 and Protein Kinase R. Jim Boonyaratanakornkit et al.J. Virol., Feb 2011; 85: 1495 - 1506. HPIV1 C proteins shared by C, C Y1, and Y2 by ProSci (Poway, CA), against a synthetic peptide.
15. Phosphorylation of polynucleotide kinase/ phosphatase by DNA-dependent protein kinase and ataxia-telangiectasia mutated regulates its association with sites of DNA damage.Angela E. Zolner et al.Nucleic Acids Res., Aug 2011; 10.1093. phospho-specific antibodies to serine 114, (ProSci Inc).
16. The cyclin-dependent kinase inhibitor p21 is regulated by RNA-binding protein PCBP4 via mRNA stability.Ariane Scoumanne et al.Nucleic Acids Res., Jan 2011; 39: 213 - 224. Anti-PCBP4 was from ProSci Incorporated (Poway, CA, USA).
17. Cancer-Associated Loss-of-Function Mutations Implicate DAPK3 as a Tumor-Suppressing Kinase. John Brognard et al.Cancer Res., Apr 2011; 71: 3152 - 3161. DAPK3 (ZIPK) antibody was purchased from ProSci Incorporated.
18. MicroRNA-301 Mediates Proliferation and Invasion in Human Breast Cancer.Wei Shi et al.Cancer Res., Apr 2011; 71: 2926 - 2937. SKA2 protein was detected using a rabbit anti-SKA2 antibody (ProSci Inc.).
