《Rise and Fall of Epithelial Phenotype》是2005年Springer Verlag出版的圖書，作者是Savagner, Pierre。
基本介紹
- 中文名：Rise and Fall of Epithelial Phenotype
- 作者：Savagner, Pierre
- 出版社：Springer Verlag
- 出版時間：2005年7月
- 頁數：248 頁
- 定價：281.37 美元
- 裝幀：HRD
- ISBN：9780306482397
內容簡介
Epithelial phenotype is a dynamic stage of differentiation that can be modulated during several physiological or pathological events. The rapid conversion to a mesenchymal-like phenotype is called an epithelial-mesenchymal transition (EMT). "The Rise and Fall of Epithelial Phenotype" is the first book to comprehensively introduce the concept of EMT. The first part of this volume describes main examples and models and explains their physiological relevance. These examples include hydra morphogenesis, gastrulation in mouse, drosophila and sea urchin, as well as neural crest cell migration and heart morphogenesis in vertebrates. Part two reviews in detail, specific EMT molecular pathways covering extracellular induction, transduction and transcription response and modulation of cell-cell adhesion structures. It emphasizes new specific pathways with potential medical applications. EMTs can also be linked to pathological events such as wound healing and cancer progression, as detailed in this section of the book.
