Andrés RUIZ-LINARES

Andrés RUIZ-LINARES

Andrés RUIZ-LINARES,男,1962年出生,劍橋大學遺傳學博士,復旦大學生命科學學院特聘教授。

基本介紹

  • 畢業院校:劍橋大學
  • 學位/學歷:博士
  • 職業:教師
  • 專業方向:疾病和非疾病表型的基因分析和群體遺傳學研究
  • 任職院校:復旦大學生命科學學院
人物經歷,研究方向,學術成果,榮譽獎項,

人物經歷

1984年獲羅薩里奧大學醫學學士學位,1987年獲巴黎第七大學生物化學碩士學位,1991年獲劍橋大學遺傳學博士學位。1992-1994年在史丹福大學醫學院從事博士後研究,1994-1998年任哥倫比亞麥德林大學醫學院生物化學系助理教授,1998-2000年任英國倫敦帝國理工學院醫學院講師,2000-2006年任英國倫敦大學學院生物學系(高爾頓實驗室)講師、高級講師,2006-2017年任英國倫敦大學學院遺傳進化環境學系教授、名譽教授,2017年2月起任復旦大學生命科學學院特聘教授。

研究方向

疾病和非疾病表型的基因分析和群體遺傳學研究。自2012年以來,一直從事人類表型特徵的基因分析研究。通過拉丁美洲的混合人群樣本研究美洲原住民、非洲人和歐洲人的表型特徵的區別,並利用遺傳數據來推斷歐亞大陸、美洲和非洲次大陸的起源問題。

學術成果

1. Adhikari K, Chacon-Duque, Mendoza-Revilla J., Fuentes-Guajardo M., Ruiz-Linares A. (2017) The Genetic Diversity of the Americas. Annual Review of Genomics & Human Genetics. 18:277–96.
2. Adhikari K, Mendoza-Revilla J, Chacon-Duque JC, Fuentes-Guajardo M & Ruiz-Linares A (2016) Admixture in Latin America. Current opinion in genetics & development 41:106-114.
3. Adhikari K, Fuentes-Guajardo M, Quinto-Sanchez M, Mendoza-Revilla J, Camilo Chacon-Duque J, Acuna-Alonzo V, Jaramillo C, Arias W, Lozano RB, Perez GM, Gomez-Valdes J, Villamil-Ramirez H, Hunemeier T, Ramallo V, Silva de Cerqueira CC, Hurtado M, Villegas V, Granja V, Gallo C, Poletti G, Schuler-Faccini L, Salzano FM, Bortolini MC, Canizales-Quinteros S, Cheeseman M, Rosique J, Bedoya G, Rothhammer F, Headon D, Gonzalez-Jose R, Balding D & Ruiz-Linares A (2016) A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation. Nat Commun 7:11616.
4. Adhikari K, Fontanil T, Cal S, Mendoza-Revilla J, Fuentes-Guajardo M, Chacon-Duque JC, Al-Saadi F, Johansson JA, Quinto-Sanchez M, Acuna-Alonzo V, Jaramillo C, Arias W, Barquera Lozano R, Macin Perez G, Gomez-Valdes J, Villamil-Ramirez H, Hunemeier T, Ramallo V, Silva de Cerqueira CC, Hurtado M, Villegas V, Granja V, Gallo C, Poletti G, Schuler-Faccini L, Salzano FM, Bortolini MC, Canizales-Quinteros S, Rothhammer F, Bedoya G, Gonzalez-Jose R, Headon D, Lopez-Otin C, Tobin DJ, Balding D & Ruiz-Linares A (2016) A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features. Nat Commun 7:10815.
5. Adhikari K, Reales G, Smith AJ, Konka E, Palmen J, Quinto-Sanchez M, Acuna-Alonzo V, Jaramillo C, Arias W, Fuentes M, Pizarro M, Barquera Lozano R, Macin Perez G, Gomez-Valdes J, Villamil-Ramirez H, Hunemeier T, Ramallo V, Silva de Cerqueira CC, Hurtado M, Villegas V, Granja V, Gallo C, Poletti G, Schuler-Faccini L, Salzano FM, Bortolini MC, Canizales-Quinteros S, Rothhammer F, Bedoya G, Calderon R, Rosique J, Cheeseman M, Bhutta MF, Humphries SE, Gonzalez-Jose R, Headon D, Balding D & Ruiz-Linares A (2015) A genome-wide association study identifies multiple loci for variation in human ear morphology. Nat Commun 6:7500.
6. Ruiz-Linares A, Adhikari K, Acuna-Alonzo V, Quinto-Sanchez M, Jaramillo C, Arias W, Fuentes M, Pizarro M, Everardo P, de Avila F, Gomez-Valdes J, Leon-Mimila P, Hunemeier T, Ramallo V, Silva de Cerqueira CC, Burley MW, Konca E, de Oliveira MZ, Veronez MR, Rubio-Codina M, Attanasio O, Gibbon S, Ray N, Gallo C, Poletti G, Rosique J, Schuler-Faccini L, Salzano FM, Bortolini MC, Canizales-Quinteros S, Rothhammer F, Bedoya G, Balding D & Gonzalez-Jose R (2014) Admixture in Latin America: geographic structure, phenotypic diversity and self-perception of ancestry based on 7,342 individuals. PLoS Genet 10(9):e1004572.
7. Ruiz-Linares A (2014) How genes have illuminated the history of early Americans and Latino Americans. Cold Spring Harb Perspect Biol 7(6).

榮譽獎項

1986-1988. CESTA fellow of the French Ministry of Research.
1988-1991. Overseas Research Student (ORS) Award from the Vice-Chancellors and Principals of the Universities of the United Kingdom.
1993. Genetics Society of America award.
1995. Ciba (now Novartis) Foundation Fellow.
2002. Young Investigator Award. The National Alliance for Research on Schizophrenia and Depression (USA).
2002-2005. Editorial board member. Annals of Human Genetics.
2005-2007. Senior Editor. Annals of Human Genetics.
2008-2015. Editor in Chief. Annals of Human Genetics.
2014-2016. Nominations Committee member. American Society of Human Genetics.

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