齊緒峰,研究員,博士生導師,再生醫學教育部重點實驗室、發育與再生生物學系PI。入選廣東省傑青、廣東省特支計畫青年拔尖人才、珠江科技新星、廣東高校優秀青年創新人才培育計畫等。目前,已在Aging Cell、FASEB J、J Mol Cell Cardiol、Cell Death Dis、Br J Pharmacol、Sci Rep、J Cell Physiol、J Cell Mol Med、Mol Immunol、Toxicol Lett等國際期刊上發表了論文30餘篇,申請發明專利10餘項(已授權3項)。圍繞上述研究工作,已經主持:國家自然科學基金(3項)、國家重點研發計畫子課題、省部級科研項目共10餘項。
基本介紹
- 中文名:齊緒峰
- 職業:教師
- 畢業院校:韓國延世大學
- 學位/學歷:博士
- 專業方向:心臟衰老與再生機制及靶向干預、基因編輯與動物疾病模型研發
- 職務:暨南大學博士生導師
學習經歷,工作經歷,研究方向,學術成果,主要論文,承擔課題,發明專利,講授課程,榮譽獎勵,社會職務,
學習經歷
2010年8月,博士畢業於韓國延世大學
2006年7月,碩士畢業於華中農業大學
2003年7月,本科畢業於山東農業大學
工作經歷
2015.10--至今暨南大學再生醫學教育部重點實驗室、發育與再生生物學系研究員
2011.10-2015.09暨南大學再生醫學教育部重點實驗室、發育與再生生物學系副教授
2010.09-2011.09暨南大學再生醫學教育部重點實驗室講師
2011.10-2015.09暨南大學再生醫學教育部重點實驗室、發育與再生生物學系副教授
2010.09-2011.09暨南大學再生醫學教育部重點實驗室講師
研究方向
(1)心臟衰老與再生機制及靶向干預
(2)基因編輯技術與動物疾病模型研發
學術成果
主要論文
1.Mao CZ, Zheng L, Zhou YM, Wu HY, Xia JB, Liang CQ, Guo XF, Peng WT, Zhao H, Cai WB, Kim SK, Park KS, Cai DQ*,Qi XF*. CRISPR/Cas9-mediated efficient and precise targeted integration of donor DNA harboring double cleavage sites in Xenopus tropicalis. FASEB J. 2018:fj201800093.
2. Wang Z, Chen Y, Chen X, Zheng X, Xu G, Yuan Z, Zhao H, Chen W, Li L, Zheng N, Shen X, Li Y,Qi X*, Cai D*. The TrkB‐T1 receptor mediates BDNF‐induced migration of aged cardiac microvascular endothelial cells by recruiting Willin.Aging Cell. 2018,DOI: 10.1111/acel.12881.
3. Zhou DC, Su YH, Jiang FQ, Xia JB, Wu HY, Chang ZS, Peng WT, Song GH, Park KS, Kim SK, Cai DQ*, Zheng L*,Qi XF*. CpG oligodeoxynucleotide preconditioning improves cardiac function after myocardial infarction via modulation of energy metabolism and angiogenesis. J Cell Physiol. 2018, 233(5):4245-4257.
4. Xia JB, Wu HY, Lai BL, Zheng L, Zhou DC, Chang ZS, Mao CZ, Liu GH, Park KS, Zhao H, Kim SK, Song GH, Cai DQ*,Qi XF*. Gene delivery of hypoxia-inducible VEGF targeting collagen effectively improves cardiac function after myocardial infarction. Sci Rep. 2017, 7(1):13273.
5. Liu GH, Mao CZ, Wu HY, Zhou DC, Xia JB, Kim SK, Cai DQ, Zhao H,Qi XF*. Expression profile of rrbp1 genes during embryonic development and in adult tissues of Xenopus laevis. Gene Expr Patterns. 2017, 23-24:1-6.
6. Liao S, Dong W, Lv L, Guo H, Yang J, Zhao H, Huang R, Yuan Z, Chen Y, Feng S, Zheng X, Huang J, Huang W,Qi X*, Cai D*. Heart regeneration in adultXenopus tropicalisafter apical resection.Cell Biosci. 2017, 7: 70.
7. Xia JB, Liu GH, Chen ZY, Mao CZ, Zhou DC, Wu HY, Park KS, Zhao H, Kim SK, Cai DQ*,Qi XF*. Hypoxia/ischemia promotes CXCL10 expression in cardiac microvascular endothelial cells by NFkB activation. Cytokine. 2016, 81:63-70.
8. Xia JB, Mao CZ, Chen ZY, Liu GH, Wu HY, Zhou DC, Park KS, Zhao H, Kim SK, Cai DQ*,Qi XF*. The CXCL10/CXCR3 axis promotes cardiac microvascular endothelial cell migration via the p38/FAK pathway in a proliferation-independent manner. Exp Mol Pathol. 2016, 100(2):257-65.
9. Ignacio RM, Kim CS, Kim YD, Lee HM,Qi XF*, Kim SK*. Therapeutic effect of Active Hexose-Correlated Compound (AHCC) combined with CpG-ODN (oligodeoxynucleotide) in B16 melanoma murine model. Cytokine. 2015, 76(2):131-137.
10.Qi XF*, Chen ZY, Xia JB, Zheng L, Zhao H, Pi LQ, Park KS, Kim SK, Lee KJ, Cai DQ*. FoxO3a suppresses the senescence of cardiac microvascular endothelial cells by regulating the ROS-mediated cell cycle. J Mol Cell Cardiol. 2015, 81:114-26.
11.Qi XF*, Zheng L, Lee KJ, Kim DH, Kim CS, Cai DQ, Wu Z, Qin JW, Yu YH, Kim SK*. HMG-CoA reductase inhibitors induce apoptosis of lymphoma cells by promoting ROS generation and regulating Akt, Erk and p38 signals via suppression of mevalonate pathway. Cell Death & Disease, 2013, 4:e518.
12.Qi XF*, Kim DH, Lee KJ, Kim CS, Song SB, Cai DQ, Kim SK*. Autophagy contributes to apoptosis in A20 and EL4 lymphoma cells treated with fluvastatin. Cancer Cell Int. 2013, 13(1):111.
13.Qi XF*, Li YJ, Chen ZY, Kim SK, Lee KJ, Cai DQ*. Involvement of the FoxO3a pathway in the ischemia/reperfusion injury of cardiac microvascular endothelial cells. Exp Mol Pathol. 2013, 95(2):242-7.
14.Qi XF*, Zheng L, Kim CS, Lee KJ, Kim DH, Cai DQ, Qin JW, Yu YH, Wu Z, Kim SK*. CpG oligodeoxynucleotide induces apoptosis and cell cycle arrest in A20 lymphoma cells via TLR9-mediated pathways. Mol Immunol. 2013, 54(3-4):327-37.
15.Qi XF, Kim DH, Yoon YS, Song SB, Teng YC, Cai DQ, Lee KJ*. Bambusae caulis in Liquamen Suppresses the Expression of Thymus and Activation-Regulated Chemokine and Macrophage-Derived Chemokine in Human Keratinocytes due to Antioxidant Effect. Evid Based Complement Alternat Med. 2012;2012:617494.
16.Qi XF, Kim DH, Yoon YS, Kim SK, Cai DQ, Teng YC, Shim KY, Lee KJ*. Involvement of oxidative stress in simvastatin-induced apoptosis of murine CT26 colon carcinoma cells. Toxicol Lett. 2010 Dec 15;199(3):277-87.
17.Qi XF, Teng YC, Yoon YS, Kim DH, Cai DQ, Lee KJ*. Reactive oxygen species are involved in the IFN-γ-stimulated production of Th2 chemokines in HaCaT keratinocytes. J Cell Physiol. 2011 Jan;226(1):58-65.
18. Park SK,Qi XF*, Song SB, Kim DH, Teng YC, Yoon YS, Kim KY, Li JH, Jin D, Lee KJ*. Electrolyzed-reduced water inhibits acute ethanol-induced hangovers in Sprague-Dawley rats. Biomed Res. 2009 Oct;30(5):263-9.
19.Qi XF, Kim DH, Yoon YS, Li JH, Jin D, Teng YC, Kim SK, Lee KJ*. Fluvastatin inhibits expression of the chemokine MDC/CCL22 induced by interferon-gamma in HaCaT cells, a human keratinocyte cell line. Br J Pharmacol. 2009 Aug;157(8):1441-50.
20.Qi XF, Kim DH, Yoon YS, Jin D, Huang XZ, Li JH, Deung YK, Lee KJ*. Essential involvement of cross-talk between IFN-gamma and TNF-alpha in CXCL10 production in human THP-1 monocytes. J Cell Physiol. 2009 Sep;220(3):690-7.
21.Qi XF, Kim DH, Yoon YS, Li JH, Song SB, Jin D, Huang XZ, Teng YC, Lee KJ*. The adenylyl cyclase-cAMP system suppresses TARC/CCL17 and MDC/CCL22 production through p38 MAPK and NF-кB in HaCaT keratinocytes. Mol Immunol, 2009, 46(10): 1925-1934.
22.Qi XF, Kim DH, Yoon YS, Li JH, Jin D, Deung YK, Lee KJ*. Effects of Bambusae caulis in Liquamen on the development of atopic dermatitis-like skin lesions in hairless mice. J Ethnopharmacol, 2009, 123(2): 195-200.
承擔課題
1.國家自然科學基金-面上項目(81770240),2018.1-2021.12,主持。
2.國家自然科學基金-面上項目(81570222),2016.1-2019.12,主持。
3.國家自然科學基金-面上項目(81270183),2013.1-2016.12,主持。
4.國家自然科學基金-青年基金項目(81100079),2012.1-2014.12,主持。
5.國家自然科學基金-國際合作與交流項目(81211140351),2012.7-2014.6,主持。
6.廣東省自然科學基金-傑出青年基金項目(2014A030306011,2015.1-2019.1,主持。
7.廣東省科技計畫-協同創新與平台環境建設專項(2014A050503043),2015.10-2017.9,主持。
8.廣東省特支計畫-百千萬工程青年拔尖人才計畫入選者,2014年度。
9.廣東省自然科學基金-面上項目(S2013010013598),2013.10-2015.10,主持。
10.廣東省自然科學基金-博士啟動基金項目(S2011040003230),2011.10-2013.10,主持。
11.廣州市珠江科技新星專項(2014J2200002),2014.4-2017.3,主持。
12.教育部留學回國人員科研啟動基金(2013-693),2013.9-2016.8,主持。
13.國家重點研發計畫-戰略性國際科技創新合作重點專項(2016YFE0204700),2017,9-2020.8,方向負責人。
發明專利
1.HMG-CoA還原酶抑制劑氟伐他汀在製備抗淋巴瘤藥物中的套用.專利授權號:ZL201210439734.0(第一完成人)
2.一種有效抑制大鼠FoxO3a基因表達的shRNA及其製備方法與套用.專利授權號:ZL201410178685.9(第一完成人)
3.一種水循環自淨繁殖和養殖蛙的裝置.專利授權號:ZL201521112382.3(第三完成人)
講授課程
本科課程:《再生生物學》
碩士課程:《幹細胞研究進展》
博士課程:《再生醫學研究技術前沿》
榮譽獎勵
省級青年人才
社會職務
中國生物物理學會衰老生物學分會理事
廣東省醫學會細胞治療學分會青年委員
中國細胞生物學會會員