黃漫娜

黃漫娜,女,中山大學化學工程與技術學院副研究員。

基本介紹

  • 中文名:黃漫娜
  • 出生地:廣東潮州
  • 出生日期:1987年8月
  • 職業:教師
  • 畢業院校:中山大學
基本情況,教育經歷,科研方向,科研項目,論著一覽,

基本情況

出生年月:1987年8月
籍貫:廣東潮州
職位:博士,副研究員

教育經歷

2006年9月—2010年7月,中山大學,學士學位;
2010年9月—2015年7月,中山大學,博士學位,導師:萬一千教授;
2012年11月—2013年10月,美國北卡羅來納大學教堂山分校醫學院,訪問學者,合作導師:柯衡明教授。
工作經歷
2016/03 - 至今,中山大學,化學工程與技術學院,副研究員
2015/07 – 2016/03,中山大學,化學與化學工程學院,副研究員

科研方向

1)功能有機分子的設計與綠色合成;2)有機藥物化學

科研項目

1.新型抗耐藥菌藥物-NDM1抑制劑的研究(中山大學青年教師培育項目,主持)

論著一覽

Huang, M.; Yu, R.; Xu, K.; Ye, S.; Kuang S.; Zhu X.*;Wan, Y.*, An Arch-bridge-type Fluorophore for Bridging the Gap Between Aggregation-caused Quenching (ACQ) and Aggregation-induced Emission (AIE).Chem. Sci., 2016, DOI: 10.1039/C6SC01254J
Huang, M.; Shao, Y.; Hou, J.; Cui, W.; Liang, B.; Huang, Y.; Li, Z.; Wu, Y.; Zhu, X.; Liu, P.; Wan, Y.*; Ke, H.*; Luo, H.-B.*, Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor.Mol. pharmacol.2015,88(5), 836-45. (共同第一作者)
Huang, M.; Huang, D.; Zhu, X.*; Wan, Y.*, Copper-Catalyzed Domino Reactions for the Synthesis of Phenothiazines.Eur. J. Org. Chem.2015,2015(22), 4835-4839.
Shao, Y.-x.;Huang, M.; Cui, W.; Feng, L.-J.; Wu, Y.; Cai, Y.; Li, Z.; Zhu, X.; Liu, P.; Wan, Y.*; Ke, H.*; Luo, H.-B.*, Discovery of a Phosphodiesterase 9A Inhibitor as a Potential Hypoglycemic Agent.J. Med. Chem.2014,57(24), 10304-10313. (共同第一作者)
Huang, M.; Hou, J.; Yang, R.; Zhang, L.; Zhu, X.*; Wan, Y.*, A Catalyst System, Copper/N-Methoxy-1H-pyrrole-2-carboxamide, for the Synthesis of Phenothiazines in Poly(ethylene glycol).Synthesis2014,46(24), 3356-3364.
Tian, Y.; Cui, W.;Huang, M.; Robinson, H.; Wan, Y.; Wang, Y.*; Ke, H.*, Dual specificity and novel structural folding of yeast phosphodiesterase-1 for hydrolysis of second messengers cyclic adenosine and guanosine 3',5'-monophosphate.Biochemistry2014,53(30), 4938-4945. (共同第一作者)
Huang, M.; Wang, L.; Zhu, X.; Mao, Z.; Kuang, D.; Wan, Y.*, Amination of Aryl Halides by Using an Environmentally Benign, Recyclable Copper Catalyst.Eur. J. Org. Chem.2012, (26), 4897-4901.
Huang, M.; Lin, X.; Zhu, X.; Peng, W.; Xie, J.; Wan, Y.*, A Highly Versatile Catalytic System for N-Arylation of Amines with Aryl Chlorides in Water.Eur. J. Org. Chem.2011, 4523–4527.
Sun, G.; Ren, S.; Zhu, X.*;Huang, M.; Wan, Y., Direct Arylation of Pyrroles via Indirect Electroreductive C-H Functionalization Using Perylene Bisimide as an Electron-Transfer Mediator.Org. Lett.2016, 18 (3), 544-547.
Song, S.;Huang, M.; Li, W.; Zhu, X.; Wan, Y.*, Efficient synthesis of indoles from 2-alkynylaniline derivatives in water using a recyclable copper catalyst system.Tetrahedron2015, 71 (3), 451-456.
Shang, N.-N.; Shao, Y.-X.; Cai, Y.-H.; Guan, M.;Huang, M.; Cui, W.; He, L.; Yu, Y.-J.; Huang, L.; Li, Z.; Bu, X.-Z.*; Ke, H.*; Luo, H.-B.*, Discovery of 3-(4-hydroxybenzyl)-1-(thiophen-2-yl)chromeno[2,3-c]pyrrol-9(2H)-one as a phosphodiesterase-5 inhibitor and its complex crystal structure.Biochem. Pharmacol.2014, 89 (1), 86-98.
Wang, L.;Huang, M.; Zhu, X.; Wan, Y.*, Polyethylene glycol (PEG-200)-promoted sustainable one-pot three-component synthesis of 3-indole derivatives in water.Appl. Catal. A: Gen.2013, 454, 160-163.
Meng, F.; Hou, J.; Shao, Y. X.; Wu, P. Y.;Huang, M.; Zhu, X.; Cai, Y.; Li, Z.; Xu, J.; Liu, P.; Luo, H. B.*; Wan, Y.*; Ke, H.*, Structure-Based Discovery of Highly Selective Phosphodiesterase-9A Inhibitors and Implications for Inhibitor Design.J. Med. Chem.2012, 55 (19), 8549-8558.
Xie, J.; Tian, J.; Su, L.;Huang, M.; Zhu, X.; Ye, F.*; Wan, Y.*, Pyrrolo[2,3-c]azepine derivatives: A new class of potent protein tyrosine phosphatase 1B inhibitors.Bioorg Med. Chem. Lett.2011, 21 (14), 4306-4309.
Xie, J.; Zhu, X.;Huang, M.; Meng, F.; Wang, M.; Wan, Y.*, Sc(OTf)3, a highly efficient and renewable catalyst for Michael addition of indoles to nitroolefins in water.Synthetic Commun.2010, 40 (21), 3259-3267.
Xie, J.; Zhu, X.;Huang, M.; Meng, F.; Chen, W.; Wan, Y.*, Pyrrole-2-carbohydrazides as Ligands for Cu-Catalyzed Amination of Aryl Halides with Amines in Pure Water.Eur. J. Org. Chem.2010, (17), 3219-3223.

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