基本介紹
- 中文名：漢族
- 畢業院校：浙江大學，廣州中醫藥大學
- 性別：男
- 職稱：研究員
人物簡介,研究方向,科研成果,人物榮譽,代表論著,
人物簡介
研究方向
經皮新劑型與新技術：包括化學藥物/中藥有效成分經皮新劑型與新技術，經皮疫苗給藥研究。
生物技術藥物輸送系統研究：包括新型載體材料的製備，載體與大分子藥物的相互作用，載體給藥系統與生物屏障的相互作用，生物大分子黏膜給藥研究，以及大分子藥物靶向給藥研究。
科研成果
主要從事生物技術藥物製劑研究。在蛋白、基因類大分子給藥系統研究中取得系列研究成果。例如，使用透皮抗原實現疫苗非注射接種的研究發表於 Angewandte Chem. Int. Ed.,並且被該刊選為新聞亮點報導。此外，該研究還受到US New and World Report及其他媒體的關注和報導。至今共發表學術論文19篇（SCI 13篇，EI 1篇），參寫專著2部。
人物榮譽
2019年8月2日，入選2019年度國家傑出青年科學基金建議資助項目申請人名單。
代表論著
HY Wang, QQ Guo, YF Jiang, EG Liu, YX Zhao, HX Wang2, YP Li*, YZ Huang*. Co-delivery of Cell-permeable Chimeric Apoptosis AVPIR8 Peptide/p53 DNA for Cocktail Therapy. Advanced Functional Materials
QQ Guo, HY Wang, YX Zhao, HX Wang, F Zeng, HY Hua, Q Xu, YZ Huang*, Cell-penetrating albumin conjugates for enhanced doxorubicin delivery. Polymer Chemistry
Y Wang, EG Liu, XY Sun, P Huang, H Long, H Wang, YZ Huang*. Pluronic L61 as a long-circulating modifier for enhanced liposomal delivery of cancer drugs, Polymer Chemistry
YZ Huang*, YF Jiang, HY Wang, JX Wang, HN He, V Yang*. Curb Challenges of the "Trojan Horse" Approach: Smart Strategies in Achieving Effective yet SafeCell-penetrating Peptide-based Drug Delivery, Advanced Drug Delivery Reviews
L Yan, HY Wang, YF Jiang, JH Liu, Z Wang, YX Yang, SW Huang, YZ Huang*. Cell-penetrating Peptide-modified PLGA Nanoparticles for Enhanced Nose-to-brain Macromolecular Delivery, Macromolecular Research
YJ Sun, WB Dong, HY Wang, YZ Huang*, HK Gu, V Yang*, J Gong*. Template Synthesis of PMAA@Chitosan Hollow Nanorods for Docetaxel Delivery. Polymer Chemistry
HN He, JY Sheng, AE David, YM Kwon, J Zhang, YZ Huang, JX Wang*, VC Yang*. The use of low molecular weight protamine chemical chimera to enhance monomeric insulin intestinal absorption
JH Liu, YX Zhao, Q Guo, Z Wang, HY Wang, YX Yang, YZ Huang*, TAT-modified Nanosilver for Combating Multidrug-resistant Cancer. Biomaterials
M Shen, YZ Huang, LM Hana, J Qin, V Yang, JX Wang*. Multidisciplinary drug delivery system for targeting tumor and its acidic microenvironment. Journal of Controlled Release
YS Park, A David, YZ Huang, J Park, HN He, Y Byun, V Yang*. In vivo delivery of cell permeable antisense-HIF1a-oligonucleotide to adipose tissue reduces adiposity in obese mice. Journal of Controlled Release
YX Yang, YF Jiang, Z Wang, JH Liu, L Yan, JX Ye, YZ Huang*. Skin-permeable Quaternary Nanoparticles with Layer-by-layer Structure Enabling Improved Gene Delivery. Journal of Material Chemistry
JX Wang, YZ Huang, A David, B Chertok, L Zhang, FQ Yu, V Yang*. Magnetic nanoparticles for brain tumors imaging. Current Pharmaceutical Biotechnology.
S Wang, H Wang, WQ Liang*, YZ Huang*. An Injectable Hybrid Nanoparticle-in-Oil-in-Water Submicron Emulsion for Improved Delivery of Poorly Soluble Drugs. Nanoscale Research Letters
SY Dong, S Wang, CH Zheng, WQ Liang*, YZ Huang*. An in situ-forming, solid lipid/PLGA hybrid implant for long-acting antipsychotics. Soft Matter
YX Yang, Y Gao, LL Chen, YZ Huang*, YP Li*. Downregulation of survivin expression and enhanced chemosensitivity of MCF-7 cells to adriamycin by PDMAE/survivin shRNA complex nanoparticles. International Journal of Pharmaceutics.
YZ Huang, YF Rao, JL Chen, V Yang*, WQ Liang. Polysorbate cationic synthetic vesicle for gene delivery.Journal of Biomedical Materials Research - Part A.
YZ Huang, YS Park, C Moon, A David, HS Chung, V Yang*. Synthetic skin-permeable proteins enabling needleless immunization. Angewandte Chemie International Edition
YZ Huang, FQ Yu, YS Park, JX Wang, MC Shin, HS Chung, V Yang*. Co-administration of protein drugs with gold nanoparticles to enable percutaneous delivery. Biomaterials
FQ Yu, L Zhang, YZ Huang, A David, V Yang*, The magnetophoretic mobility and superparamagnetism of core-shell iron oxide nanoparticles with dual targeting and imaging functionality. Biomaterials
YS Park, YZ Huang, YJ Park, A David, L White, HN He, HS Chung, V Yang*. Specific down regulation of 3T3-L1 adipocyte differentiation by cell-permeable antisense HIF1á-oligonucleotide. Journal of Controlled Release.
XL Zheng, YZ Huang, CH Zheng*, SY Dong, WQ Liang. Alginate-Chitosan-PLGA composite microspheres enabling single-shot hepatitis B vaccination. The AAPS Journal.
YZ Huang, YS Park, JX Wang, C Moon, YM Kwon, HS Chung, V Yang*. ATTEMPTS system: a macromolecular prodrug strategy for cancer drug delivery. Current Pharmaceutical Design
