高衛平，男，畢業於青島化工學院，現任職於北京大學跨學部生物醫學工程系研究員。
基本介紹
- 中文名：高衛平
- 國籍：中國
- 畢業院校：青島化工學院
教育經歷,學術簡歷,研究方向,獲得榮譽,代表論文,
教育經歷
2000.09 - 2004.06 北京大學 高分子化學與物理專業博士；
1993.09 - 2000.06 青島化工學院高分子工程專業本科與碩士；
學術簡歷
2018.12 - ~ 北京大學跨學部生物醫學工程系研究員，博士生導師；
2011.10 - 2018.11 清華大學醫學院生物醫學工程系研究員，博士生導師；
2007.05 - 2011.08 美國杜克大學生物醫學工程系博士後；
2005.05 - 2007.04 日本京都大學化學研究所博士後。
研究方向
高分子/超分子生物材料（Polymeric/Supramolecular Biomaterials）；智慧型/仿生生物材料(Intelligent/Bioinspired Biomaterials)；蛋白質-高分子偶聯物（Protein-Polymer Conjugates）；癌症納米醫學（Cancer nanomedicine）
獲得榮譽
2017年 清華大學優秀博士學位論文一等獎導師獎；
2016年 拜耳研究員獎；
2012年 楊森研究員獎；
2007年 中國科協優秀學術論文獎；
1996年 化工部科技興化獎。
代表論文
22. Zhuoran Wang, Jianwen Guo, Jing Ning, Xiaoyu Feng, Xinyu Liu, Jiawei Sun, Xiangmei Chen, Fengmin Lu,Weiping Gao. One-month zero-order sustained release and tumor eradication after a single subcutaneous injection of interferon alpha fused with a body-temperature-responsive polypeptide.Biomater. Sci.2019,7, 104-112.
21. Pengyong Li, Mengmeng Sun, Zhikun Xu, Xinyu Liu, Wenguo Zhao,Weiping Gao. Site-selective in situ growth-induced self-assembly of protein-polymer conjugates into pH-responsive micelles for tumor microenvironment triggered fluorescence imaging.Biomacromolecules2018,19, 4472-4479.
20. Xinyu Liu, Mengmeng Sun, Jiawei Sun, Jin Hu, Zhuoran Wang, Jianwen Guo,Weiping Gao.Polymerization induced self-assembly of a site-specific interferona-block copolymer conjugate into micelles with remarkably enhanced pharmacology.J. Am. Chem. Soc.2018,140,10435-10438.
19. Mengmeng Sun, Jianwen Guo, Hanjun Hao, Tong Tong, Kun Wang,Weiping Gao*. Tumour-homing chimeric polypeptide-conjugated polypyrrole nanoparticles for imaging-guided synergistic photothermal and chemical therapy of cancer.Theranostics2018,8, 2634-2645.
18. Xinyu Liu, Jiawei Sun,Weiping Gao.Site-selective protein modification with polymers for advanced biomedical applications.Biomaterials2018, 178, 413-434.
17. Xinyu Liu, Jin Hu, Jianwen Guo, Guilin Wang,Weiping Gao. Temperature-responsive polymer conjugation of interferon-aenhances antitumor efficacy.Acta Polym. Sin.2018,1, 90-98.
16. Zhuoran Wang, Qiong He, Wenguo Zhao, Jianwen Luo,Weiping Gao. Tumor-homing, pH- and ultrasound-responsive polypeptide-doxorubicin nanoconjugates overcome doxorubicin resistance in cancer therapy.J. Control. Release2017,264,66-75.
15. Wenguo Zhao, Jin Hu,Weiping Gao*.Glucose oxidase-polymer nanogels for synergistic cancer-starving and oxidation therapy.ACS Appl. Mater. Interfaces2017,9，23528-23535.
14. Mengmeng Sun, Dong Peng, Hanjun Hao, Jin Hu, Dongliang Wang, Kun Wang, Jing Liu, Ximin Guo, Yen Wei,Weiping Gao*. Thermally triggered in situ assembly of gold nanoparticles for cancer multimodal imaging and photothermal therapy.ACS Appl. Mater. Interfaces2017,9,10453-10460.
13. Xinyu Liu,Weiping Gao*. In situ growth of self-assembled protein-polymer nanovesicles for enhanced intracellular protein delivery.ACS Appl. Mater. Interfaces2017,9, 2023-2028.
12. Guilin Wang, Jin Hu,Weiping Gao. Tuning the molecular size of site-specific interferon-polymer conjugate for optimized antitumor efficacy.Sci. China Mater.2017,60，563-570.
11. Jin Hu, Guilin Wang, Wenguo Zhao,Weiping Gao*.In situ growth of a C-terminal interferon-alpha conjugate of a phospholipid polymer that outperforms PEGASYS in cancer therapy.J. Control. Release2016,237, 71-77.
10. Jin Hu, Guilin Wang, Wenguo Zhao, Xinyu Liu, Libin Zhang,Weiping Gao*.Site-specific in situ growth of an interferon-polymer conjugate that outperforms PEGASYS in cancer therapy.Biomaterials2016,96, 84-92.
9. Mengmeng Sun, Fei Liu, Yukun Zhu, Wansheng Wang, Jin Hu, Jing Liu, Zhifei Dai, Kun Wang, Yen Wei, Jing Bai,Weiping Gao. Salt-induced Aggregation of Gold nanoparticles for photoacoustic imaging and photothermal therapy of cancer.Nanoscale2016,8, 4452-4457.
8. Jin Hu, Guilin Wang, Xinyu Liu,Weiping Gao. Enhancing pharmacokinetics, tumor accumulation and antitumor efficacy by elastin-like polypeptide fusion of interferon alpha.Adv. Mater.2015,27, 7320-7324.
7. Libin Zhang, Wenguo Zhao, Xinyu Liu, Guilin Wang, Yang Wang, Dong Li, Liangzhi Xie, Yan Gao, Haiteng Deng,Weiping Gao. Site-selective in situ growth of fluorescent polymer-antibody conjugates with enhanced antigen detection by signal amplification.Biomaterials2015,64, 2-9.
6. Jin Hu, Lining Xie, Wenguo Zhao, Mengmeng Sun, Xinyu Liu,Weiping GaoDesign of tumor-homing and pH-responsive polypeptide-doxorubicin nanoparticles with enhanced anticancer efficacy and reduced side effects.Chem. Commun.2015,51, 11405-11408.
5. Wenguo Zhao, Fei Liu, Yue Chen, Jing Bai,Weiping Gao. Synthesis of well-defined protein-polymer conjugates for biomedicine.Polymer2015,66, A1-A10.
4. Jin Hu, Wenguo Zhao, Yan Gao, Mengmeng Sun, Yen Wei, Haiteng Deng,Weiping Gao. Site-specific in situ growth of a cyclized protein-polymer conjugate with improved stability and tumor retention.Biomaterials2015,47, 13-19.
3.Weiping Gao, Wenge Liu, Trine Christensen, Michael R. Zalutsky, Ashutosh Chilkoti*.In situgrowth of a PEG-like polymer from the C-terminus of an intein fusion protein improves pharmacokinetics and tumor accumulation.Proc. Natl. Acad. Sci. USA2010,107, 16432-16437.
2.Weiping Gao, Wenge Liu, J. Andrew Mackay, Michael R. Zalutsky, Eric J. Toone, Ashutosh Chilkoti*.In situgrowth of a stoichiometric PEG-like conjugate at a protein’s N-terminus with significantly improved pharmacokinetics.Proc. Natl. Acad. Sci. USA2009,106, 15231–15236.
1. Weiping Gao, Yu Bai, Erqiang Chen*, Zichen Li*, Bingyong Han, Wantai Yang, QifengZhou*. Controlling vesicle formation via interpolymer hydrogen-bonding complexation between poly(ethylene oxide)-block-polybutadiene and poly(acrylic acid) in solution.Macromolecules2006,39, 4894-4898.
