馮亞凱，男，1966年12月出生，天津大學化工學院教授，博導。
天津市化工學會委員，天津市生物醫學工程學會委員
Polymers for Advanced Technologies, Journal of Cellular Biotechnology, International Journal of Polymer Science, The Scientific World Journal, Current Advances in Chemistry Research, Cardiovascular regenerative medicine, Research Journal of Chemistry and Environment，Frontiers of Chemical Science and Engineering，納米技術(NanoTechnology)，Open Journal of Polymer Chemistry，Chinese Journal of Engineering，合成化學研究，中國組織工程研究等期刊編委,“中國科技論文線上”評審專家
基本介紹
個人履歷,講授課程,代表論文,獲得專利,
個人履歷
1989和1992年於南開大學獲高分子專業本科和碩士學位。
1992年6月～1997年7月在天津大學化工學院工作，1997年獲得天津大學有機化工工學博士，1997年8月作為教育部公派訪問學者留學德國。
2000年10月獲得亞琛工業大學理學博士學位，從事醫用共分子材料研究。
2000-2001年在亞琛工業大學生物中心作博士後，
2001年10月-2003年9月德國ADIAM生命科學股份有限公司生物材料部主管，高分子家，2003年10月-2007年3月，德國GKSS研究中心高分子材料研究所和BCRT生物材料和再生治療技術研究中心化學家，負責眼科材料和多功能性材料的研發工作。
2003年4月，天津大學化工學院教授。2008年入選教育部新世紀優秀人才。
講授課程
高分子物理，生物材料與組織工程
研究領域（方向）:
多功能高分子材料，醫用高分子材料，藥物緩釋，
參加學術團體:
天津市化工學會委員，天津市生物醫學工程學會委員，美國化學會會員，Research Journal of Chemistry and Environment 海外編委
課題成果:
完成的項目：
1. 人工合成材料製作心臟瓣膜研究開發，ADIAM 生命科學技術有限公司資助項目
2. 人工合成材料製作細徑心血管研究開發，ADIAM 生命科學技術有限公司資助項目
3. 生物相容形狀記憶材料，德國聯邦教育研究部
4. 眼科材料和再生治療的研究，德國聯邦教育研究部
5. 生物材料研發和再生醫學研究，德國聯邦教育研究部
代表論文
曾在國內外刊物上發表論文40餘篇，24篇被SCI檢索，申請發明專利2項。有關的成果如下：
代表性論著：
研究論文
1. Armin Alteheld, Yakai Feng, Steffen Kelch, and Andreas Lendlein
Biodegradable Amorphous Copolyester-Urethane Networks Having Shape-Memory Properties
Angewandte Chemie International Edition 2005, 44, 1188-1192
2. Andreas Lendlein, Joerg Zotzmann,Yakai Feng, Armin Alteheld, Steffen Kelch
Controlling the switching temperature of biodegradable, amorphous shape-memory poly(rac-lactide)urethane networks by incorporation of different Comonomers, Biomacromolecules, 2009， 10 (4), 975–982
3. Marc Behl, Ute Ridder, Yakai Feng, Steffen Kelch, Andreas Lendlein, Shape-memory capability of binary multiblock copolymer blends with hard and switching domains provided by different components, Soft Matter, 2009, 5(3), 676-684
4. Yakai Feng, Marc Behl, Steffen Kelch, Andreas Lendlein
Biodegradable Multiblock Copolymers Based on Oligodepsipeptides with Shape-Memory Properties, Macromol. Biosci. 2009, 9(1), 45-54.
5. J. Zotzmann, M. Behl, Y. Feng, and A. Lendlein
Copolymer Networks Based on Poly(w-pentadecalactone) and Poly(e-caprolactone) Segments as a Versatile Triple-Shape Polymer System，Adv. Funct. Mater. 2010, 20(20), 3583–3594.
6. Yakai Feng, Shifeng Zhang, Li Zhang, Jintang Guo, and Yongshen Xu，Synthesis and Characterization of hydrophilic Polyester-PEO Networks with Shape-memory Properties， Polym. Adv. Technol. 2011, 22(12), 2430-2438
7. Yakai Feng, Jian Lu, Marc Behl, Andreas Lendlein, Degradable depsipeptide-based multiblock copolymers having polyester or polyetherester segments, The International Journal of Artificial Organs, 2011; 34(2): 103-109.
8. Yakai Feng, Haiyang Zhao, Licai Jiao, Jian Lu, Heyun Wang, Jintang Guo, Synthesis and Characterization of Biodegradable, Amorphous, Soft IPNs with Shape-memory Effect, Polymers for Advanced Technologies 2012, 23, 382-388
9. Heyun Wang, Yakai Feng, Bo An, Wencheng Zhang, Minglin Sun, Zichen Fang, Wenjie Yuan, Massuri Khan, Fabrication of PU/PEGMA crosslinked hybrid scaffolds by in situ UV photopolymerization favoring human endothelial cells growth for vascular tissue engineering, J Mater Sci: Mater Med, 2012.23(6):1499-1510
10. Yakai Feng, Haiyang Zhao, Marc Behl, Andreas Lendlein, Jintang Guo, and Dazhi Yang, Grafting of Poly(ethylene glycol) Monoacrylates on Polycarbonateurethane by UV Initiated Polymerization for Improving Hemocompatibility, Journal of Materials Science-Materials in Medicine, 2013,24, 61-70.
11. Li Zhang, Yakai Feng, Hong Tian, Miao Zhao, Musammir Khan, Jintang Guo, Amphiphilic Depsipeptide-Based Block Copolymers as Nanocarriers for Controlled Release of Ibuprofen with Doxorubicin, J. Polym. Sci., Part A: Polym. Chem. 2013, 51（15）, 3213–3226
12. Musammir Khan, Yakai Feng, Dazhi Yang, Wei Zhou, Hong Tian, Ying Han, Li Zhang, Wenjie Yuan, Jin Zhang, Jintang Guo, Wencheng Zhang, Biomimetic Design of Amphiphilic Polycations and Surface Grafting onto Polycarbonate Urethane Film as Effective Antibacterial Agents with Controlled Hemocompatibility, J. Polym. Sci., Part A: Polym. Chem. 2013, 51（15）, 3166–3176
13. Wenjie Yuan, Yakai Feng, Heyun Wang, Dazhi Yang, Bo An, Wencheng Zhang, Musammir Khan, Jintang Guo, Hemocompatible surface of electrospun nanofibrous scaffolds by ATRP modification，Materials Science and Engineering C 2013, 33（7）, 3644-3651
14. Li Zhang, Yakai Feng, Juan Lv, Jing Yang, Hong Tian, Changcan Shi, Miao Zhao, Jintang Guo, Controlled release of doxorubicin from amphiphilic depsipeptide-PDO-PEG-based copolymer nanosized microspheres, Reactive & Functional Polymers, 2013,73（9）, 1281–1289.
15. Cangcan Shi, Fanglian Yao, Jiawen Huang, Guoliang Han, Qian Li, Musammir Khan, Yakai Feng, Wencheng Zhang, Proliferation and Migration of Human Vascular Endothelial Cells Mediated by ZNF580 Gene Complexed with mPEG-b-P(MMD-co-GA)-g-PEI Microparticles, Journal of materials chemistry B, Materials for biology and medicine. 2014, 2(13), 1825-1837
16. Changcan Shi, Fanglian Yao, Jiawen Huang, Qian Li, Musammir Khan, Yakai Feng, Wencheng Zhang, Regulation of the Endothelialization by Human Vascular Endothelial Cells by ZNF580 Gene Complexed with Biodegradable Microparticles, Biomaterials, 2014, 35, 7133-7145
17. Miao Zhao, Yakai Feng, Guang Li, Yuan Li,Yalong Wang, Ying Han, Xujun Sun, Xiaohua Tan, Synthesis of An Adhesion-enhancing Polysiloxane Containing Epoxy Groups for Addition-cure Silicone Light Emitting Diodes (LEDs) Encapsulant, Polymers for Advanced Technologies, 2014, 25, 927-933.
1. Armin Alteheld, Yakai Feng, Steffen Kelch, and Andreas Lendlein
Biodegradable Amorphous Copolyester-Urethane Networks Having Shape-Memory Properties
Angewandte Chemie International Edition 2005, 44, 1188-1192
2. Andreas Lendlein, Joerg Zotzmann,Yakai Feng, Armin Alteheld, Steffen Kelch
Controlling the switching temperature of biodegradable, amorphous shape-memory poly(rac-lactide)urethane networks by incorporation of different Comonomers, Biomacromolecules, 2009， 10 (4), 975–982
3. Marc Behl, Ute Ridder, Yakai Feng, Steffen Kelch, Andreas Lendlein, Shape-memory capability of binary multiblock copolymer blends with hard and switching domains provided by different components, Soft Matter, 2009, 5(3), 676-684
4. Yakai Feng, Marc Behl, Steffen Kelch, Andreas Lendlein
Biodegradable Multiblock Copolymers Based on Oligodepsipeptides with Shape-Memory Properties, Macromol. Biosci. 2009, 9(1), 45-54.
5. J. Zotzmann, M. Behl, Y. Feng, and A. Lendlein
Copolymer Networks Based on Poly(w-pentadecalactone) and Poly(e-caprolactone) Segments as a Versatile Triple-Shape Polymer System，Adv. Funct. Mater. 2010, 20(20), 3583–3594.
6. Yakai Feng, Shifeng Zhang, Li Zhang, Jintang Guo, and Yongshen Xu，Synthesis and Characterization of hydrophilic Polyester-PEO Networks with Shape-memory Properties， Polym. Adv. Technol. 2011, 22(12), 2430-2438
7. Yakai Feng, Jian Lu, Marc Behl, Andreas Lendlein, Degradable depsipeptide-based multiblock copolymers having polyester or polyetherester segments, The International Journal of Artificial Organs, 2011; 34(2): 103-109.
8. Yakai Feng, Haiyang Zhao, Licai Jiao, Jian Lu, Heyun Wang, Jintang Guo, Synthesis and Characterization of Biodegradable, Amorphous, Soft IPNs with Shape-memory Effect, Polymers for Advanced Technologies 2012, 23, 382-388
9. Heyun Wang, Yakai Feng, Bo An, Wencheng Zhang, Minglin Sun, Zichen Fang, Wenjie Yuan, Massuri Khan, Fabrication of PU/PEGMA crosslinked hybrid scaffolds by in situ UV photopolymerization favoring human endothelial cells growth for vascular tissue engineering, J Mater Sci: Mater Med, 2012.23(6):1499-1510
10. Yakai Feng, Haiyang Zhao, Marc Behl, Andreas Lendlein, Jintang Guo, and Dazhi Yang, Grafting of Poly(ethylene glycol) Monoacrylates on Polycarbonateurethane by UV Initiated Polymerization for Improving Hemocompatibility, Journal of Materials Science-Materials in Medicine, 2013,24, 61-70.
11. Li Zhang, Yakai Feng, Hong Tian, Miao Zhao, Musammir Khan, Jintang Guo, Amphiphilic Depsipeptide-Based Block Copolymers as Nanocarriers for Controlled Release of Ibuprofen with Doxorubicin, J. Polym. Sci., Part A: Polym. Chem. 2013, 51（15）, 3213–3226
12. Musammir Khan, Yakai Feng, Dazhi Yang, Wei Zhou, Hong Tian, Ying Han, Li Zhang, Wenjie Yuan, Jin Zhang, Jintang Guo, Wencheng Zhang, Biomimetic Design of Amphiphilic Polycations and Surface Grafting onto Polycarbonate Urethane Film as Effective Antibacterial Agents with Controlled Hemocompatibility, J. Polym. Sci., Part A: Polym. Chem. 2013, 51（15）, 3166–3176
13. Wenjie Yuan, Yakai Feng, Heyun Wang, Dazhi Yang, Bo An, Wencheng Zhang, Musammir Khan, Jintang Guo, Hemocompatible surface of electrospun nanofibrous scaffolds by ATRP modification，Materials Science and Engineering C 2013, 33（7）, 3644-3651
14. Li Zhang, Yakai Feng, Juan Lv, Jing Yang, Hong Tian, Changcan Shi, Miao Zhao, Jintang Guo, Controlled release of doxorubicin from amphiphilic depsipeptide-PDO-PEG-based copolymer nanosized microspheres, Reactive & Functional Polymers, 2013,73（9）, 1281–1289.
15. Cangcan Shi, Fanglian Yao, Jiawen Huang, Guoliang Han, Qian Li, Musammir Khan, Yakai Feng, Wencheng Zhang, Proliferation and Migration of Human Vascular Endothelial Cells Mediated by ZNF580 Gene Complexed with mPEG-b-P(MMD-co-GA)-g-PEI Microparticles, Journal of materials chemistry B, Materials for biology and medicine. 2014, 2(13), 1825-1837
16. Changcan Shi, Fanglian Yao, Jiawen Huang, Qian Li, Musammir Khan, Yakai Feng, Wencheng Zhang, Regulation of the Endothelialization by Human Vascular Endothelial Cells by ZNF580 Gene Complexed with Biodegradable Microparticles, Biomaterials, 2014, 35, 7133-7145
17. Miao Zhao, Yakai Feng, Guang Li, Yuan Li,Yalong Wang, Ying Han, Xujun Sun, Xiaohua Tan, Synthesis of An Adhesion-enhancing Polysiloxane Containing Epoxy Groups for Addition-cure Silicone Light Emitting Diodes (LEDs) Encapsulant, Polymers for Advanced Technologies, 2014, 25, 927-933.
18. Miao Zhao, Yakai Feng, Yuan Li, Guang Li, Yalong Wang, Ying Han, Xujun Sun, Xiaohua Tan, Fabrication of Siloxane Hybrid Material with High Adhesion and High Refractive Index for Light Emitting Diodes (LEDs) Encapsulation, Journal of Macromolecular Science, Part A: Pure and Applied Chemistry, 2014, 51(8): 653-658.
19. Miao Zhao, Yakai Feng, Yuan Li, Guang Li, Yalong Wang, Ying Han, Xujun Sun, Xiaohua Tan, Preparation and Performance of Phenyl-Vinyl-POSS/Addition-type Curable Silicone Rubber Hybrid Material, Journal of Macromolecular Science, Part A: Pure and Applied Chemistry, 2014, 51(8): 639-645.
20. Li Zhang, Yakai Feng, Bibliometrics and visualization analysis of artificial blood vessel research, Current Science, 2014, 106(6), 816-822.
21. Li Yu, Xuefang Hao, Qian Li, Changcan Shi, Yakai Feng, Electrospun PLGA/SF modified with electrosprayed microparticles: a novel biomimetic composite scaffold for vascular tissue engineering, Adv. Mater. Res. 2014, 1015, 336-339.
22. Juan Lv, Li Zhang, Musammir Khan, Xiangkui Ren, Jintang Guo, Yakai Feng, Biodegradable depsipeptide-PDO-PEG-based block copolymer micelles as nanocarriers for controlled release of doxorubicin, Reactive and Functional Polymers, 2014, 82, 89-97.
23. 於麗，馮亞凱，石常燦，郝雪芳，嗎啉-2，5-二酮衍生物及其聚合物的研究進展, 高分子通報, 2015，3：18~25.
24. 周偉，馮亞凱, 靜電紡絲SF/PLGA纖維支架用於血管組織工程的研究, 化學工業與工程
25. Musammir Khan, Jing Yang, Changcan Shi, Yakai Feng,* Wencheng Zhang, Katie Gibney, Gregory N. Tew, Manipulation of polycarbonate urethane bulk properties via incorporated zwitterionic polynorbornene for tissue engineering application，RSC Advances, 2015, 5, 11284-11292.
26. Wei Zhou, Yakai Feng*, Jing Yang, Jiaxu Fan1, Juan Lv , Li Zhang, Jintang Guo, Xiangkui Ren*, WenchengZhang, Electrospun membranes of silk fibroin and poly(lactide-co-glycolide) as potential nonthrombogenic scaffolds for vascular tissue engineering application, Journal of Materials Science: Materials in Medicine. DOI 10.1007/s10856-015-5386-6
27. Changcan Shi, Fanglian, Yao, Wenjie Yuan, Musammir Khan, Qian Li, Yakai Feng,* Wencheng Zhang, Hydrophilic PCU scaffolds prepared by grafting PEGMA and immobilizing gelatin to enhance cell adhesion and proliferation, Material Science and Engineering C 50 (2015) 201–209.
28．Qian Li, Changcan Shi, Jiawen Huang, Jing Yang, Yakai Feng*, Wencheng Zhang, Marc Behl, and Andreas Lendlein, Self-assembly Complexed Gene Nanoparticles to Promote the Proliferation of Human Vascular Endothelial Cells, Advanced Healthcare Materials, DOI: 10.1002/adhm.201400817
29. Haixia Wang, Yakai Feng*, Jing Yang, Jintang Guo* and Wencheng Zhang*, Targeting REDV peptide functionalized polycationic gene carrier for enhancing the transfection and migration capability of human endothelial cells. Journal of Materials Chemistry B 2015, 3, 3379-3391
30. Li Yu, Yakai Feng*, Qian Li, Xuefang Hao, Wen Liu, Wei Zhou, Changcan Shi, Xiangkui Ren*, Wencheng Zhang*, PLGA/SF blend scaffolds modified with plasmid complexes for enhancing proliferation of endothelial cells. Reactive and Functional Polymers, 2015, 91-92, 19–27
31. Musammir Khan, Jing Yang, Changcan Shi, Yakai Feng*, Wencheng Zhang, Katie Gibney, Gregory N. Tew*, Surface Modification of Polycarbonate Urethane with Zwitterionic Polynorbornene via Thiol-ene Click-Reaction to Facilitate Cell Growth and Proliferation, Macromolecular Materials and Engineering, DOI:10.1002/mame.201500038
32. Musammir Khan, Jing Yang, Changcan Shi, Juan Lv, Yakai Feng *, Wencheng Zhang *, Surface tailoring for selective endothelialization and platelet inhibition via a combination of SI-ATRP and Click-chemistry using Cys-Ala-Gly-peptide, Acta Biomaterialia, 2015, 20, 69–81
33. Xiangkui Ren, Yakai Feng*, Jintang Guo, Haixia Wang, Qian Li, Jing Yang, Xuefang Hao, Juan Lv, Nan Ma*, Wenzhong Li, Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering application, Chemical Society Reviews，已接收
34. Xuefang Hao#, Qian Li #, Juan L, Li Yu, Xiangkui Ren, Li Zhang, Yakai Feng*, Wencheng Zhang*, CREDVW-linked polymeric micelles as a targeting gene transfer vector for selective transfection and proliferation of endothelial cells, ACS Appl. Mater. Interfaces, 已接收
獲得專利
Yakai Feng, Steffen Kelch, Andreas lendlein
Multiblockcopolymere mit Formgedächtniseigenschaften
2006, Nr. 10 2006 023365.4
