馬超美

馬超美

馬超美，女，內蒙古大學生命科學院生物系教授

1979.9-1983.7 北京醫學院藥學系（現北京大學藥學院）學士

1996.4-1998.3 日本富山醫科藥科大學（現與富山大學合併）藥學碩士

1998.4-2001.3 日本富山醫科藥科大學（現與富山大學合併）藥學博士

基本介紹

  • 中文名：馬超美
  • 國籍：中國
  • 民族：漢族
  • 畢業院校： 北京醫學院
研究領域,研究活動,教育,工作經歷,部分論文,

研究領域

天然藥物與功能食品研究
馬超美教授馬超美教授

研究活動

1．植物成分的提取、分離和結構測定。
如：鎖陽（Cynomorium songaricum）、文冠木（Xanthoceras sorbifolia）等中蒙藥的生物活性成分研究。
2．植物成分衍生物及類似物的合成和生物活性研究。
如：綠原酸衍生物和類似物的製備及生物活性，三萜類化合物的結構改造及生物活性等。
3．植物成分體內外代謝研究。
如：生物鹼的體內代謝產物的結構測定等。

教育

1998.4-2001.3 日本富山醫科藥科大學（現與富山大學合併）藥學博士
1996.4-1998.3 日本富山醫科藥科大學（現與富山大學合併）藥學碩士
1979.9-1983.7 北京醫學院藥學系（現北京大學藥學院）學士

工作經歷

2010.5- 內蒙古大學生命科學院生物系 教授
2006.7-2010.3 日本富山大學和漢醫藥學綜合研究所 副教授
2003.3-2006.7 加拿大紐芬蘭記念大學藥學院 博士後
2001.5-2003.3 北京大學藥學院 講師-副教授
1994.4-1996.3 日本富山醫科藥科大學和漢藥研究所 世川研修生-客員研究員
1983.8-1994.3 內蒙古醫學院藥學系 助教-講師

部分論文

  1. Jin J. S., Tobo T., Chung M. H., Ma, C. M.; Hattori M. Transformation of trachelogenin, an aglycone of tracheloside from safflower seeds, to phytoestrogenic (−)-enterolactone by human intestinal bacteria.Food Chem134: 74-80 (2012).
  2. Kitalong, C.; El-Halawany, A. M.; El-Dine, R. S.; Ma, C. M.; Hattori, M. Phenolics fromPhaleria nisidaiwith estrogenic activity.Rec Nat Prod6: 296-300. (2012).
  3. Zhong, Y.; Ma, C.M.; Shahidi, F. Antioxidant and antiviral activities of lipophilic epigallocatechin gallate (EGCG) derivatives.J Functional Foods.4: 87-93 (2012).
  4. Wang, Z. G.; Wang, X. J.; Sun, H.; Chen, L.; Ma, C.M.Determination of novel nitrogen-containing metabolite after oral administration of swertiamarin to rats.J Asian Nat Prod Res.14: 176-181 (2012).
  5. Nakamura, K.; Nishihata, T.; Jin, J-S.; Ma, C. M.; Komatsu, K.; Iwashima, M.; Hattori, M. TheC-glucosyl bond of puerarin was cleaved hydrolytically by a human intestinal bacterium strain PUE to yield its aglycone daidzein and an intact glucose.Chem PharmBull.59: 23-27 (2011).
  6. Ma, C-M.; Abe, T.; Komiyama, T.; Wang, W.; Hattori, M.; Daneshtalab, M. Synthesis, anti-fungal and 1,3-ß-D-glucan synthase inhibitory activities of caffeic and quinic acid derivatives.Bioorg Med Chem18: 7009-7014 (2010).
  7. Ma, C. M.; Kawahata, T.; Hattori, M.; Otake, T.;Wang, L.; Daneshtalab, M. Synthesis, anti-HIV and anti-oxidant activities of caffeoyl 5,6-anhydroquinic acid derivatives.Bioorg Med Chem18: 863-869 (2010).
  8. Ma, C. M.;Sato, N.; Li, X. Y.; Nakamura, N.; Hattori, M. Flavan-3-ol contents, anti-oxidative and -glucosidase inhibitory activities ofCynomorium songaricum.Food Chem118: 116-119 (2010).
  9. Ma, C. M.; Wei, Y.; Wang, Z. G.; Hattori, M. Triterpenes fromCynomorium songaricum—analysis of HCV protease inhibitory activity, quantification, and content change under the influence of heating.J Nat Med63: 9-14 (2009).
  10. Ma, C. M.; Hattori, M.; Daneshtalab, M.; Wang, L. Chlorogenic Acid Derivatives with Alkyl Chains of Different Lengths and Orientations: Potent a-Glucosidase Inhibitors.J Med Chem51: 6188-6194 (2008).
  11. Ma, C. M.; Hattori, M.; Chen, H. B.; Cai, S.-Q.; Daneshtalab, M.Profiling the Phenolic Compounds ofArtemisia pectinataby HPLC-PAD-MS.Phytochem Analysis19: 294-300 (2008).
  12. Ma, C. M.;Kully, M.; Khan, J. K.; Hattori, M.; Daneshtalab, M. Synthesis of chlorogenic acid derivatives with promising antifungal activity.Bioorg Med Chem.15: 6830-6833 (2007).
  13. Ma, C. M.;Winsor, L.; Daneshtalab, M.Quantification of spiroether isomers and herniarin of different parts ofMatricaria matricarioidesand flowers ofChamaemelum nobile. Phytochem Analysis. 18:42-49 (2007).
  14. Ma, C. M.;Takeda, S.; Hibino, S.; Daneshtalab,M. Synthesis of peptidomimetic analogues of echinocandines.Heterocycles,68: 721-732, (2006).）
  15. Ma, C. M.;Cai, S. Q.; Cui, J. R.; Wang, R. Q.; Tu, P. F.; Hattori, M.; Daneshtalab, M. The cytotoxic activity of ursolic acid derivatives.Eur J Med Chem40: 582-589 (2005).
  16. Wang, W.; Ma, C. M.; Hattori, M. Metabolism and Pharmacokinetics of Rhynchophylline in Rats.Bio Pharm Bull33: 669-676 (2010).
  17. Wang, W.; Ma, C. M.; Hattori, M. Simultaneous determination of rhynchophylline, isorhynchophylline, and their eight metabolites in rats.J Trad Med27: 15-29 (2010).
  18. Wei, Y.; Ma, C. M.; Hattori, M. Synthesis and evaluation of A-secotypetriterpenoids for anti-HIV-1 protease activity.Eur J Med Chem44: 4112-4120 (2009).
  19. Sato, N.; Ma, C. M.; Komatsu, K.; Hattori, M.Triterpene-farnesyl hydroquinone conjugates fromGanoderma sinense.J Nat Prod72: 958-961 (2009).
  20. Wei, Y.; Ma, C. M.; Hattori, M. Synthesis of dammarane-type triterpene derivatives and their ability to inhibit HIV and HCV proteases.Bioorg Med Chem17: 3003-3010 (2009).
  21. Wei, Y.; Ma, C. M.; Hattori, M. Anti-HIV protease triterpenoids from the acid hydrolysate ofPanax ginseng.Phytochemistry Letters2:63-66 (2009).
  22. Phuong, D. T.; Ma, C. M.; Hattori, M.; Jin, J. S. Inhibitory Effects of Antrodins A-E fromAntrodia cinnamomeaand Their Metabolites on Hepatitis C Virus Protease.Phytother Res23:582-584 (2009).
  23. Yu, J,; Ma, C. M.;Long, C. F.; Wang, X.; Shang, M. Y.; Cai, S. Q.; Hattori, M.; Namba, T. A new aristololactam fromAsarum maximum. Journal of Chinese Pharmaceutical Sciences18:183–185 (2009).
  24. Xu, Q.; Ma, C. M.; Wang, W.; Fu, X.; Tang C. Y.; Hattori, M. Study on the nitric oxide generating effects from aristolochic acidin vitro.Eur J Mass Spectrom14: 231-238(2008).
  25. Wei Y; Ma, C. M.; Chen D. Y; Hattori M.Anti-HIV-1 protease triterpenoids fromStauntonia obovatifoliolaHayata subsp.intermedia.Phytochemistry69: 1875-1879 (2008).
  26. Wang, Z. G.; Ma C. M.; Tang, S. H.; Xiao, H,;Kakiuchi, N.; Kida, H.; Hattori, M. Qualitative and Quantitative Analysis of Swertia Herbs by High Performance Liquid Chromatography-Diode Array Detector-Mass Spectrometry (HPLC-DAD-MS).Chem Pharm Bull56: 485-490 (2008).
  27. Lee, J. S.; Ma, C. M.; Hattori, M. Quantification of ergosterol and ergosterol peroxide in several medicinal fungi by high performance liquid chromatography monitored with a diode array detection-atmospheric pressure chemical ionization-ion trap mass spectrometer.J Trad Med25: 18-23 (2008).
  28. Lee, J. S.; Ma, C. M.; Park, D. K.; Yoshimi, Y.; Hatanaka, M.; Hattori, M. Transformation of ergosterol peroxide to cytotoxic substances by rat intestinal bacteria.Bio Pharm Bull31: 949-54 (2008).
  29. Dong, S. W.; Wang, X.; Shang, M.Y.; Ma, C. M.; Zhang, S. X.; Li, X. W.; Xu, M. J.; Cai, S. Q.; Namba, T. Sesquiterpene and Aristolochic Acid Derivatives from Thottea hainanensis,Helvetica Chimica Acta: 354 – 360. 2010.
  30. Wang, J.; Chung M. H.; Xue B.; Ma H.; Ma, C. M.; Hattori, M. Estrogenic and Antiestrogenic Activities of Phloridzin.Bio Pharm Bull33,592-597, 2010.
  31. El Dine, R. S.; El Halawany, A. M.; Ma, C. M.;Hattori, M. Inhibition of the dimerization and active site of HIV-1 protease by secondary metabolites from the Vietnamese mushroom Ganoderma colossum.J Nat Prod.72:2019-23 (2009).
  32. Sato, N.; Zhang, Q.; Ma, C. M.; Hattori, M. Anti-HIV-1 protease activity of new lanostain-type triterpenoids fromGanoderma sinense.Chem Pharm Bull57: 1076-1080 (2009).
  33. Zhang, Q.; Zuo, F.; Nakamura, N.; Ma, C. M.; Hattori, M.Metabolism and pharmacokinetics in rats of ganoderiol F, a highly cytotoxic and antitumor triterpene fromGanoderma lucidum.J Nat Med.63: 304-310 (2009).
  34. El Dine, R. S.; El Halawany, A. M.; Ma, C. M.;Hattori, M. Anti-HIV-1 Protease Activity of Lanostane Triterpenes from the Vietnamese MushroomGanoderma colossum. J. Nat. Prod.71: 1022-1026 (2008).
  35. Wang, Z. G.; Tang, S. H.; Ma C. M.; Toyooka,N.; Kida, H.; Kawasaki,M.; Hattori, M. Determination of novel nitrogen-containing metabolites after oral administration of swertiamarin to rats.J Trad Med25: 29-34 (2008).
  36. El Dine, R. S.; El Halawany, A. M.; Nakamura, N.; Ma, C. M.; Hattori, M. New lanostane triterpene lactones from the Vietnamese mushroomGanoderma colossum(FR.) C. F. BAKER.Chem Pharm Bull56: 642-646 (2008).
  37. El-Halawany, A. M.; Chung, M. H.; Ma, C. M.; Komatsu, K.; Nishihara, T.; Hattori, M. Anti-estrogenic activity of mansorins and mansonones from the heartwood ofMansonia gageiDRUMM.Chem Pharm Bull55: 1332-1337 (2007).
  38. El-Halawany, A. M.; Chung, M. H.; Nakamura, N.; Ma, C. M.; Nishihara, T.; Hattori,M. Estrogenic and anti-estrogenic activities ofCassia toraphenolic constituents.Chem. Pharm. Bull.Vol.55: 1476-1482 (2007).
  39. Sun, Q. Z.; Chen, D. F.; Ding, P. L.; Ma, C. M.; Hiroko Kakuda, Norio Nakamura and Masao Hattori. Three New Lignans, Longipedunins A—C, fromKadsura longipedunculataand Their Inhibitory Activity against HIV-1 Protease.ChemPharm Bull54: 129-132 (2006).
  40. Zhang,C. Y.; Wang, X.; Su, T.; Ma, C. M.; Wen, Y. J.; Shang, M. Y.; Li, X. M.; Liu, G. X.; Cai, S. Q. Aristololactam and renal cytotoxic constituents from the stem and leaves ofAristolochia contorta.Pharmazie,60: 785-788 (2005).
  41. Chou, G. X.; Nakamura, N.; Ma, C. M.; Wang Z. T.; Hattori, M..Isoquinoline Alkaloids fromLindera aggregate.Chinese Journal of Natural Medicines,3: 272-275 (2005).

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