人物經歷
陳韡於2010年、2012年在華中科技大學分別獲得學士與碩士學位,於2018年獲得美國紐約州立大學石溪分校博士學位。2018年至2023年先後在美國霍華德休斯醫學院Janelia研究園區和
加州大學伯克利分校從事博士後研究,合作導師為Na Ji (吉娜)教授。2022年獲國家優秀青年科學基金項目(海外)資助。
研究方向
主要成就
科研成果
主持承擔了國家優秀青年科學基金項目等國家級項目,參與了美國“
腦計畫”重點研發項目。已在“Nature Communications”, “Cell Metabolism”, “Molecular Psychiatry” , “Elife”等頂級期刊上發表多篇高水平論文,申請美國專利1項。
學術成果
代表性論文:
[1] Wei Chen, Xinxin Ge, Qinrong Zhang, Ryan Natan, Jianglan Fang, Massimo Scanziani, Na Ji, “High-throughput volumetric mapping of synaptic transmission”, (submitted), 2023. (Technology part see:bioRxiv 2022.03.05.483143; doi: https://doi.org/10.1101/2022.03.05.483143.)
[2] Qinrong Zhang*, Yuhan Yang*, Kevin Cao, Wei Chen, Santosh Paidi, Chun-Hong Xia, Richard H. Kramer, Xiaohua Gong, Na Ji, “Retinal microvascular and neuronal pathologies probed in vivo by adaptive optical twophoton fluorescence microscopy”, eLife, 2023
[3] Rika Ohkubo*, Chih Ling Wang*, Wei-Chieh Mu*, Wei Chen, Jiang Lan Fan, Zehan Song, Andrew Widjaja, Peter Sudmant, Angela Pisco, Dena Dubal, Na Ji, Danica Chen, “The Mitochondrial Protein Folding Stress Regulates Cognitive Aging”, Cell Metabolism, 2023
[4] Wei Chen, Ryan Natan, Yuhan Yang, Shih-Wei Chou, Qinrong Zhang, and Ehud Isacoff, Na Ji, “In vivo volumetric imaging of calcium and glutamate activity at synapses with high spatiotemporal resolution”, Nature Communications, 2021
[5] Yuhan Yang, Wei Chen, Jianglai Fang, Na Ji, “Adaptive optics enables aberration-free remote focusing for two-photon fluorescence microscopy”, Biomedical Optical Express, 12 (1), 354-366,2021
[6] Wei Chen, K. Park, Nora D. Volkow, Yingtian Pan, Alan P. Koretsky, Congwu Du, “Interactions between task-evoked cortical activity and spontaneous slow oscillations measured with neuronal calcium”, NeuroImage, 210, 116554,2020
[7] Wei Chen, Nora D Volkow, James Li, Yingtian Pan, Congwu Du, “Cocaine Decreases Spontaneous Neuronal Activity and Increases Low-Frequency Neuronal and Hemodynamic Cortical Oscillations”, Cerebral Cortex, 29 (4), 1594-1606,2018.
[8] Wei Chen, Congwu Du, Yingtian Pan, “Cerebral capillary flow imaging by wavelength-divisionmultiplexing swept-source optical Doppler tomography”, Journal of Biophotonics, 11 (8), 2018.
[9] Xiaochun Gu, Wei Chen, Nora Volkow, Alan Koretsky, Congwu Du, Yingtian Pan, “Synchronized Astrocytic Ca2+ Responses in Neurovascular Coupling during Somatosensory Stimulation and for the Resting State”, Cell Reports, 23 (13), 3878-3890,2018.
[10] Xiaochun Gu, Wei Chen, Jiang You, Alan P Koretsky, ND Volkow, Yingtian Pan, Congwu Du, “Longterm optical imaging of neurovascular coupling in mouse cortex using GCaMP6f and intrinsic hemodynamic signals”, NeuroImage, 165, 251-264,2018.
[11] Kicheon Park, Wei Chen, Nora D. Volkow, Craig P. Allen, Yingtian Pan, Congwu Du, “Hemodynamic and Neuronal Responses to Cocaine Differ in Awake versus Anesthetized Animals: Optical Brain Imaging Study”, NeuroImage, 188, 188-197,2018.
[12] Wei Chen*, Peng Liu*, Nora Volkow, Yingtian Pan, and Congwu Du, "Cocaine attenuates blood flow but not neuronal responses to stimulation while preserving neurovascular coupling for resting brain activity," Molecular Psychiatry, 21 (10), 1408-1416, 2016.
[13] Wei Chen, Kicheon Park, Nora Volkow, Yingtian Pan, and Congwu Du, "Cocaine Induced Abnormal Cerebral Hemodynamic Responses to Forepaw Stimulation Assessed by Integrated Multi-wavelength Spectroimaging and Laser Speckle Contrast Imaging," IEEE Journal of Selected Topics in Quantum Electronics, 22(4):6802608,2016.
代表性專利:
[1] Yingtian Pan, Wei Chen, Congwu Du, Wavelength-division-multiplexing swept-source optical doppler tomography, U. S. Patent: US20210196126A1.
獲獎記錄
2022 “Sculpted Light in the Brain”, 旅行獎
2010 湖北省大學生優秀科研成果三等獎(第一完成人)
2009 全國大學生光電設計大賽一等獎(第一完成人)
曾任SPIE Photonics West分會主席, 受邀擔任多個國際知名期刊(Optica, Neuroimage,Engineering,Biomedical Optics Express,Optics Express,Optics Letters等)審稿人。