陳維，男，博士，教授，博士生導師，就職於工學院製藥工程。
基本介紹
- 中文名：陳維
- 職業：博士生導師
個人簡介,個人經歷,課題組研究,論文發表期刊,代表性論文,授權專利,
個人簡介
陳維，博士，教授，博士生導師，2018年入選“江蘇特聘教授”
個人經歷
2010年蘇州大學套用化學專業碩士學位，並榮獲“江蘇省優秀碩士研究生學位論文”（導師：鐘志遠教授）；
2013年荷蘭特文特大學（University of Twente）高分子化學與生物材料專業博士學位（導師：Jan Feijen教授）。
2013-2017年德國柏林自由大學（Freie Universität Berlin）博士後研究（合作導師：Rainer Haag教授），擔任組內“新型微納結構”研究方向負責人；
2015年開始主持德國洪堡博士後基金項目。
2018年入選“江蘇省特聘教授”。
課題組研究
主要涉及“智慧型型可降解納米藥物”、“功能性生物表界面塗層材料”、“微流控或靜電紡技術製備功能性細胞支架”等
目前已獲得授權的歐洲專利、美國專利和中國專利4項。
論文發表期刊
Angew. Chem.
J. Control. Release
Biomaterials
Small
Macromolecules
Acta Biomater.
Chem. Commun.
Biomacromolecules
代表性論文
1.Y. Hou, W.Y. Xie, K. Achazi, J.L. Cuellar-Camacho, M.F. Melzig,W. Chen*, and R. Haag*, Injectable Degradable PVA Microgels Prepared by Microfluidic Technology for Controlled Osteogenic Differentiation of Mesenchymal Stem Cells,Acta Biomater.2018,77, 28-37.
2.D. Huang, H. Qian, H. Qiao,W. Chen*, J. Feijen, and Z. Zhong*, Bioresponsive Functional Nanogels as An Emerging Platform for Cancer Therapy,Expert Opin. Drug Deliv.2018,15, 703-716.
3.Z. Tu, H. Qiao, Y. Yan, G. Guday,W. Chen*, M. Adeli*, and R. Haag*, Directed Graphene-Based Nanoplatforms for Hyperthermia: Overcoming Multiple Drug Resistance,Angew. Chem.2018, 130, 11368 –11372(Angew. Chem. Int. Ed.2018, 57, 11198 –11202).
4.D.C. Huang,Q. Zhang,Y. Deng,Z. Luo,B. Li,X. Shen,Z.H. Qi,S.Y. Dong*,Y. Ge*andW. Chen*, Polymeric Crown Ethers: LCST Behavior in Water and Stimuli-Responsiveness,Polym. Chem.2018, 9, 2574-2579.
5.X Huang, Y Hou, LL Zhong, D Huang*, H Qian, M Karperien, andW Chen*, Promoted Chondrogenesis of Cocultured Chondrocytes and Mesenchymal Stem Cells under Hypoxia Using In-situ Forming Degradable Hydrogel Scaffolds,Biomacromolecules2018, 19, 94-102.
6.W. Chen*, Y. Hou, Z.X. Tu, L.Y. Gao, and R. Haag*, pH-Degradable PVA-Based Nanogels via Photo-Crosslinking of Thermo-Preinduced Nanoaggregates for Controlled Drug Delivery,J. Control. Release2017, 259, 160-167.
7.W. Chen (co-first author), Y. Zou, Z.Y. Zhong*, and R. Haag*, Cyclo(RGD)-decorated Reduction-responsive Nanogels Mediate Targeted Chemotherapy of Integrin Over-expressing Human Glioblastoma In Vivo,Small2017, 13, 1601997-1602005.
8.L.Y. Gao*, B. Zheng,W. Chen*, and C.A. Schalley, Enzyme-Responsive Pillar[5]arene-Based Polymer-SubstitutedAmphiphiles: Synthesis, Self-Assembly in Water, and Application in Controlled Drug Release,Chem. Commun.2015,51, 14901-14904.
9.W. Chen,F.H. Meng, R. Cheng, C. Deng, J. Feijen*, and Z.Y. Zhong*, Facile Construction of Dual-Bioresponsive Biodegradable Micelles with Superior Extracellular Stability and Activated Intracellular Drug Release,J. Control. Release2015,210, 125-133.
10.W. Chen, F.H. Meng, R Cheng, C. Deng, J. Feijen*, and Z.Y. Zhong*,Biodegradable Glycopolymer-b-Poly(ε-caprolactone) Block Copolymer Micelles: Versatile Construction, Tailored Lactose Functionality, and Hepatoma-Targeted Drug Delivery,J. Mater. Chem. B.2015,3, 2308-2317.
11.W. Chen, K. Achazi, B. Schade, and R. Haag*, Charge-Conversional and Reduction-Sensitive Poly(vinyl alcohol) Nanogels for Enhanced Cell Uptake and Efficient Intracellular Doxorubicin Release,J. Control. Release2015,205, 15-24.
12.W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen*, and Z.Y. Zhong*, Advanced Drug and Gene Delivery Systems Based on Functional Biodegradable Polycarbonates and Copolymers,J. Control. Release2014,190, 398-414.
13.W. Chen, Y. Zou, F.H. Meng, R. Cheng, C. Deng*,J. Feijen, and Z.Y. Zhong*, Glyco-Nanoparticles with Sheddable Saccharide Shells: A Unique and Potent Platform for Hepatoma-Targeting Drug Delivery,Biomacromolecules2014,15, 900-907.
14.W. Chen, M. Zheng, F.H. Meng, R. Cheng, C. Deng,J. Feijen, and Z.Y. Zhong*, In-Situ Forming Reduction-Sensitive Degradable Nanogels for Facile Loading and Triggered Intracellular Release of Proteins,Biomacromolecules2013,14, 1214-1222.
15.W. Chen, Y. Zou, J.N. Jia, F.H. Meng, R. Cheng, C. Deng,J. Feijen, and Z.Y. Zhong*, Functional Poly(ε-caprolactone)sviaCopolymerizing ε-Caprolactone with Pyridyldisulfide-Functionalized Cyclic Carbonate Monomer: Controlled Synthesis and Facile Access to Reduction-Sensitive Biodegradable Graft Copolymer Micelles,Macromolecules2013, 46, 699–707.
16.W. Chen, P. Zhong, F.H. Meng*, R. Cheng, C. Deng,J. Feijen, and Z.Y. Zhong*,Redox and pH-Responsive Degradable Micelles for Dually Activated Intracellular Anticancer Drug Release,J. Control. Release2013, 169, 171-179.
17.R. Wang,W. Chen(co-first author), F.H. Meng, R. Cheng, C. Deng,J. Feijen, and Z.Y. Zhong*, Unprecedented Access to Functional Biodegradable Polymers and Coatings,Macromolecules2011, 44, 6009–6016.
18.W. Chen, F.H. Meng*, R. Cheng, Z.Y. Zhong*,pH-Sensitive Degradable Polymersomes for Triggered Release of Anticancer Drugs: a Comparative Study with Micelles,J. Control. Release2010, 142, 40-46（引用：340次）.
19.W. Chen, H.C. Yang, R. Wang, R. Cheng, F.H. Meng*, W.X. Wei, and Z.Y. Zhong*, Versatile Synthesis of Functional Biodegradable Polymers by Combining Ring-Opening Polymerization and Post-polymerization Modification via Michael-type Conjugate Addition Reactions,Macromolecules2010, 43, 201-207.
20.W. Chen, F.H. Meng, F. Li, S.J. Ji, and Z.Y. Zhong*, pH-Responsive Biodegradable Micelles Based on Acid-Labile Polycarbonate Hydrophobe: Synthesis andTriggered Drug Release,Biomacromolecules2009, 7, 1727-1735.
授權專利
1.Wei Chen,Rong Wang, Fenghua Meng, and Zhiyuan Zhong, A Method of Making A Polymer Preferably An (Alkyl)Acryloyl Polycarbonate, The Polymer and (Alkyl)Acryloyl Polycarbonate Obtained, and A Biodevice Comprising Same, European patent, 2016, No: EP2456764.
2.Wei Chen, Fenghua Meng, Rong Wang, Ru Cheng, and Zhiyuan Zhong, Method of Making An (Alkyl)Acryloyl Polycarbonate, US Patent, 2015, No: US8927196.
3.鐘志遠，孟鳳華，杜銀鋒，陳維，一種酸敏感可降解聚合物囊泡及其製備和套用，中國專利，2014，公開（公告）號：CN102911326.
4.陳維，王榮，孟鳳華，鐘志遠，含有丙烯酸酯類功能基團的環碳酸酯單體及其製備和套用，中國專利，2013，公開（公告）號：CN101633654.
