陳曉華，中國科學院青島生物能源與過程研究所副研究員。1993年畢業於上海第二醫科大學臨床醫學專業， 1995年前往德國，在德國柏林洪堡大學先後獲得了分子生物學碩士及博士。2003年-2011年任職於德國柏林洪堡大學微生物基因工程研究室，從事有微生物的全基因組測序，功能基因（組）的鑑定及分析，菌株的改造，菌種的分類及次級代謝產物的研究。
基本介紹
- 中文名：陳曉華
- 國籍：中國
- 畢業院校：上海第二醫科大學
- 職稱：中國科學院青島生物能源所副研究員
研究方向,代表論著,
研究方向
分子生物學
代表論著
1. Borriss R, Chen XH, Rueckert C, Blom J , Becker A, Baumgarth B, Fan B, Pukall R, Schumann P, Spröer C, Junge H, Vater J, Pühler A, Klenk HP. Relationship of Bacillus amyloliquefaciens clades associated 1 with strains DSM 7T and FZB42: a proposal for Bacillus amyloliquefaciens subsp. amyloliquefaciens subsp. nov. and Bacillus amyloliquefaciens subsp. plantarum subsp. nov. based on their discriminating complete genome sequences. Int J Syst Evol Microbiol. 2010 Sep 3. [Epub ahead of print].
2. Fan B, Chen XH, Budiharjo A; Bleiss W, Vater J, Borriss R. Efficient colonization of plant roots by the plant growth promoting bacterium Bacillus amyloliquefaciens FZB42, engineered to express green fluorescent protein. J Biotechnol. 2011 Jan 13. [Epub ahead of print].
3. Rückert C, Blom J, Chen XH, Reva O, and Borriss R. Genome sequence of B. amyloliquefaciens type strain DSM7T reveals differences to plant-associated B. amyloliquefaciens FZB42. J Biotechnol. 2011 Jan 22. [Epub ahead of print].
4. Chen XH, Scholz R, Borriss M, Junge H, Mögel G, Kunz S, Borriss R. Difficidin and bacilysin produced by plant-associated Bacillus amyloliquefaciens are efficient in controlling fire blight disease. J Biotechnol. 2009 Mar 10; 140(1-2):38-44. Epub 2008 Nov 18.
5. Chen XH, Koumoutsi A, Scholz R, Schneider K, Vater J, Süssmuth R, Piel J, Borriss R. Genome analysis of Bacillus amyloliquefaciens FZB42 reveals its potential for biocontrol of plant pathogens. J Biotechnol. 2009 Mar 10; 140(1-2):27-37. Epub 2008 Nov 12.
6. Chen XH, Koumoutsi A, Scholz R, Borriss R. More than anticipated - production of antibiotics and other secondary metabolites by Bacillus amyloliquefaciens FZB42. J Mol Microbiol Biotechnol. 2009; 16(1-2):14-24. Epub 2008 Oct 29.
7. Moldenhauer J, Chen XH, Borriss R, Piel J. Biosynthesis of the antibiotic bacillaene, the product of a giant polyketide synthase complex of the trans-AT family. Angew Chem Int Ed Engl. 2007; 46(43):8195-7. No abstract available.
8. Schneider K*, Chen XH*, Vater J, Franke P, Nicholson G, Borriss R, Süssmuth RD. Macrolactin is the polyketide biosynthesis product of the pks2 cluster of Bacillus amyloliquefaciens FZB42. J Nat Prod. 2007 Sep; 70(9):1417-23. Epub 2007 Sep 11. (* both contribute the same)
9. Koumoutsi A, Chen XH, Vater J, Borriss R. DegU and YczE positively regulate the synthesis of bacillomycin D by Bacillus amyloliquefaciens strain FZB42. Appl Environ Microbiol. 2007 Nov; 73(21):6953-64. Epub 2007 Sep 7.
10. Chen XH, Koumoutsi A, Scholz R, Eisenreich A, Schneider K, Heinemeyer I, Morgenstern B, Voss B, Hess WR, Reva O, Junge H, Voigt B, Jungblut PR, Vater J, Süssmuth R, Liesegang H, Strittmatter A, Gottschalk G, Borriss R. Comparative analysis of the complete genome sequence of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42. Nat Biotechnol. 2007 Sep; 25(9):1007-14. Epub 2007 Aug 19.
11. Chen XH, Vater J, Piel J, Franke P, Scholz R, Schneider K, Koumoutsi A, Hitzeroth G, Grammel N, Strittmatter AW, Gottschalk G, Süssmuth RD, Borriss R. Structural and functional characterization of three polyketide synthase gene clusters in Bacillus amyloliquefaciens FZB 42. J Bacteriol. 2006 Jun; 188(11):4024-36.
12. Lund P, Weisshaupt K, Mikeska T, Jammas D, Chen XH, Kuban RJ, Ungethüm U, Krapfenbauer U, Herzel HP, Schäfer R, Walter J, Sers C. Oncogenic HRAS suppresses clusterin expression through promoter hypermethylation. Oncogene. 2006 Aug 10; 25(35):4890-903. Epub 2006 Mar 27
